COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
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IF 5.518
Jing Kong,Sufen Zhang,Ming Shen,Jingui Zhang,Sabesan Yoganathan
Antibiotic resistance is a serious problem all over the world. Inorganic metal oxide nanoparticles are suitable substitutional treatments for organic antibiotic-resistant bacterial infections. Various copper dopped ZnO nanocomposites were prepared with chemical deposition method in aqueous solution. X-ray diffraction (XRD) coupled with energy dispersive spectroscopy results reveals that cuprous oxide is uniformly doped on the surface of ZnO nanoparticles , forming Cu 2 O/ZnO nanocomposites. In addition, from Transmission electron microscopy (TEM) and scanning electron microscopy analysis , the average size of prepared Cu 2 O/ZnO composite is about 30 nm. The antibacterial activity of the Cu 2 O/ZnO composite was examined on two bacteria strains: Gram-positive Staphylococcus aureus ( S. aureus ) and Gram-negative Escherichia coli ( E. coli ). When the doping amount of Cu 2 O reaches more than 5%, a 3.58 log-reduction of S. aureus growth under visible light within 30 mins treatment was observed. The antibacterial activity of Cu 2 O/ZnO is 2.7-fold higher than pure ZnO and killing bacteria on E. coli with a 1.0 log-reduction in viability. Meanwhile, the bacteriological properties of Cu doped ZnO composites with different valence states (Cu 2+ , CuO, Cu 2 O, and Cu 0 ) were compared. Furthermore, the antibacterial mechanism was further discussed in this paper.
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NANOTECHNOLOGY
·
2022
·Vol. 33
·期 17
·175603
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IF 3.953
Chen Chen,Lei Nie,Yizhe Huang,Shuang Xi,Xingyue Liu,Xiwen Zhang,Tielin Shi,Guanglan Liao,Shiyuan Liu,Zirong Tang
Herein, we develop a novel strategy for preparing all-inorganic cesium lead halide (CsPbX3, X = Cl, Br, I) perovskite nanocrystals (NCs)@Zn-based metal-organic framework (MOF) composites through interfacial synthesis. The successful embedding of fluorescent perovskite NCs in Zn-MOFs is due to the in situ confined growth, which is attributed to the re-nucleation of water-triggered phase transformation from Cs4PbBr6 to CsPbBr3. The controllable synthesis of mixed-halide based composites with various emission wavelength can be achieved by adding the desired amount of halide (Cl or I) salts in the re-nucleation process. More importantly, the anion exchange reaction is inhibited among various composites with different halogen atoms by being trapped in MOFs. Besides, a white light-emitting diode (WLED) is produced using a blue LED chip with the green-emitting and red-emitting composites, which has a color coordinate of (0.3291, 0.3272) and a wide color gamut. This work provides a novel route to achieving perovskite NCs growth in MOFs, which also can be extended to the other NCs embedded in frames as well.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2022
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IF 9.136
Fei Yu,Xueting Bai,Mingxing Liang,Jie Ma
Considering the increasingly serious levels of antibiotic pollution, it is necessary to find new and efficient adsorbents. In this study, the adsorptive removal of a model quinolone antibiotic, ciprofloxacin (CIP), from wastewater is presented using a metal–organic framework (MOF)-derived carbon. HKUST-1-derived carbon (HDC-1100) was obtained by high-temperature carbonization of the HKUST-1 precursor at 1100 °C. HDC-1100 has a regular octahedron shape decorated with Cu/Cu 2 O particles and has a microporous and mesoporous structure with abundant oxygen-containing functional groups on the surface. Within 48 h, HDC-1100 could reach adsorption equilibrium for 30 mg·L -1 CIP, and the kinetic data were fitted with a pseudo-first-order model and a pseudo-second-order model. In this study, the maximum adsorption capacity of HDC-1100 for CIP was as high as 592 mg·g −1 . The high adsorption capacity is attributed mainly to metal–organic complexation, electrostatic interactions, and hydrogen bonding. Also, the effects of environmental factors, such as pH, ionic strength, and humic acid, on the adsorption capacity were considered. This study is significant for the treatment of high-concentration antibiotic-polluted wastewater.
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CHEMICAL ENGINEERING JOURNAL
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2022
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IF 16.744
Jian Liu,Xin Wang,Fengyuan Ma,Xuechun Yang,Yunjia Liu,Xiaoyi Zhang,Shien Guo,Zhipeng Wang,Shenghong Yang,Rusong Zhao
Pursuing a selective and stable optical sensor for the reliable detection of perfluorooctane sulfonate (PFOS) is critical to controlling and reducing the risk of exposure to human. Here, we elaborately prepared an atomic copper(I)-carbon nitride (Cu-CN) peroxidase-mimic catalyst and therefore developed a reliable and accessible PFOS detection method. Well-distributed Cu(I) atoms are exclusively anchored within CN nanosized matrix as identified Cu-CN single-site active centers. Benefiting from the high peroxidase-mimic catalytic capability and colloidal stability, Cu-CN exhibits outstanding detection of PFOS selectively in the range of 0.07 to 3 μM coupled with the detection limit of 14.9 nM. The occupation of atomic Cu(I) specific catalytic sites caused by strong PFOS coordination and the fluorophilic interaction between PFOS should be responsible for the damping of TMB oxidation. Moreover, this detection platform was also used successfully to detect PFOS in three real water samples with RSD ≤ 8.37%. This well-established colorimetric sensing system based on peroxidase-mimic capability of single-atom catalyst is promising for the detection of other hazards in aquatic environment.
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Journal of Materials Chemistry C
·
2023
·Vol. 12
·期 3
·922-929
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IF 6.4
Xiangshi Bin,Jiaxing Liu,Ruosheng Zeng,Hongbang Liu,Jialong Zhao,Tao Lin
Fast and convenient synthesis of zero-dimensional (0D) cesium-copper(I) halide (Cs3Cu2X5 (X = Cl, I)) single crystals (SCs) is critical to achieve practical radiography. In this study, rapid growth of high-quality Cs3Cu2X5 (X = Cl, I) SCs with sizes reaching centimeter scale were achieved within 24 hours using scalable solution-phased methods. These crystals exhibited highly effective emission with large Stokes shifts, excellent PL linearity, and PLQYs exceeding 86%. Additionally, post-treated Cs3Cu2X5–PMMA films demonstrated outstanding scintillation performance, including excellent stabilities, light yield surpassing 36 000 photons per MeV, and spatial resolution up to 6.5 lp per mm in X-ray imaging tests. The high scintillation efficiency can be attributed to their compact 0D crystalline structure, resulting in a small defect density and strong exciton localization.
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npj Regenerative Medicine
·
2023
·Vol. 8
·期 1
·1-18
·
IF 7.2
Tu Tian,Shi Yuan,Zhou Boya,Wang Xiaoyu,Zhang Wenjie,Zhou Guangdong,Mo Xiumei,Wang Wenbo,Wu Jinglei,Liu Wei
Our previous work demonstrated the tendon-derived extracellular matrix (ECM) extracts as vital niches to specifically direct mesenchymal stem cells towards tenogenic differentiation. This study aims to further define the effective ECM molecules capable of teno-lineage induction on human adipose-derived stem cells (hASCs) and test their function for tendon engineering. By detecting the teno-markers expression levels in hASCs exposed to various substrate coatings, collagen I (COL1) and fibromodulin (FMOD) were identified to be the key molecules as a combination and further employed to the modification of poly(L-lactide- co -ε-caprolactone) electrospun nanoyarns, which showed advantages in inducting seeded hASCs for teno-lineage specific differentiation. Under dynamic mechanical loading, modified scaffold seeded with hASCs formed neo-tendon in vitro at the histological level and formed better tendon tissue in vivo with mature histology and enhanced mechanical properties. Primary mechanistic investigation with RNA sequencing demonstrated that the inductive mechanism of these two molecules for hASCs tenogenic differentiation was directly correlated with positive regulation of peptidase activity, regulation of cell-substrate adhesion and regulation of cytoskeletal organization. These biological processes were potentially affected by LOC101929398/has-miR-197-3p/TENM4 ceRNA regulation axis. In summary, COL1 and FMOD in combination are the major bioactive molecules in tendon ECM for likely directing tenogenic phenotype of hASCs and certainly valuable for hASCs-based tendon engineering.
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International Journal of Polymer Science
·
2023
·
IF 3.3
Chunhai Ke,Xuanyuan Lu,Jiahua Ni,Ruicong Li,Qi Chen,Zhaoxiang Peng
There has been an increase in the incidence of meniscus injuries worldwide, as well as growing needs for injectable hydrogels with the potentials to promote in situ meniscal tissue repair. This work developed poly(N-isopropylacrylamide)-collagen I composite hydrogels, with a series of different collagen I contents. The hydrogels were injectable under room temperature and started to solidify around 32°C due to their thermosensitivities, meeting the requirements of the intended applications. The addition of collagen I to the poly(N-isopropylacrylamide) provided physical reinforcement to the hydrogels. Rheological characterizations showed that, under room temperature, the complex viscosity, the storage modulus, and the loss modulus, respectively, increased from Pa•s to Pa•s, from Pa to Pa, and from Pa to Pa, as the collagen I content in the hydrogel increased from 0% to 1%. Cell proliferation tests and high-density culture also revealed that collagen I promoted bioactivity of the hydrogels and induced fibrochondrocyte phenotype of the chondrocytes. The expressions of collagen I protein and collagen I a1 gene in the PNIPAm-0.5Coll group were 3.50-fold and 3.64-fold of those in the PNIPAm group. In contrast, the expressions of collagen II protein and collagen II a1 gene were less prominent (respectively, 2.36-fold and 3.34-fold in the PNIPAm-0.5Coll group compared with the PNIPAm group). This phenotyping was believed to be conducive to the regeneration of meniscal tissues. The findings of this study have provided an important basis for future in vivo studies and clinical applications of this type of composite hydrogels.
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MICROCHEMICAL JOURNAL
·
2023
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IF 4.8
Shuqian Wang,Jinli Qin,Yin Liang,Youai Ye,Shushu Li,Yamei Guo,Xiao Yang,Yong Liang
This paper proposes a selective strategy for quantitative detecting cardiac troponin I (cTnI) in clinical serum samples by using Raman spectroscopy combined with magnetic molecularly imprinted polymers (MMIPs). The signature peptide was selected as a template for molecular imprinting due to its chemical stability and small molecular mass. MMIPs were synthetized with the signature peptide as template and methylacrylic acid as monomer in presence of vinyl-modified magnetic particles. MMIPs with high magnetic character and adsorption properties were able to be stained by Coomassie Brilliant Blue G-250 after the target template was specifically captured, which showing a characteristic absorption peak at Raman shift 1610 cm −1 . The Raman signal intensity at 1610 cm −1 showed a linear relationship in the 0.01 to 100 ng·mL −1 concentration range. The recovery of cTnI in serum were 92.7–111.2 % with relative standard deviation in the range of 2.51 % to 8.52 %. This paper has important practical application for preliminary rapid detection of cTnI in clinical serum samples.
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NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
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2023
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IF 3.6
Deng Shanshan,Gao Yuan,Lv Mengting,Li Xinyu,Ma Yulin,Guo Yuchen,Li Tiejun,Zhang Yuefan
Chronic cerebral hypoperfusion (CCH) is the leading cause of chronic cerebral dysfunction syndrome with its complex pathological mechanisms involving cortical and hippocampal neuronal loss, white matter lesions, and neuroinflammation. I-C-F-6 is a septapeptide, which has anti-inflammatory and anti-fibrotic effects. This study aimed to evaluate the neuroprotective effect of I-C-F-6 in chronic cerebral hypoperfusion (CCH)-induced neurological injury. C57BL/6 J mice were subjected to bilateral common carotid artery stenosis (BCAS), and BV2 microglia cells were induced with oxygen-glucose deprivation (OGD). In vivo, mice were divided randomly into four groups: Sham, BCAS, GBE (30 mg/kg), and I-C-F-6 (0.5 mg/kg). In vitro, microglia were divided randomly into four groups: control, OGD, I-C-F-6 (25 μg/mL), and Shikonin (800 nmol/L). Through LFB, TUNEL, and NeuN staining, we found that I-C-F-6 was able to mitigate myelin pathology and reduce the number of apoptotic neurons. Furthermore, immunofluorescence staining revealed that I-C-F-6 was able to reduce microglia clustering and downregulate NF-κB p65. We also observed a significant downregulation of M1 phenotype microglia signature genes, such as TNF-α, iNOS, and upregulation of anti-inflammatory cytokines, such as Arg-1 and IL-10, indicating that I-C-F-6 may mainly reduce polarization towards the M1 phenotype in microglia. Notably, I-C-F-6 downregulated the expression of NF-κB signaling pathway-related proteins IKK-β and NF-κB p65, as well as pro-inflammatory cytokines IL-1β and iNOS. In conclusion, I-C-F-6 can improve neurological damage, alleviate neuroinflammation, and inhibit microglia polarization to the M1 phenotype via the NF-κB signaling pathway.
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SCIENCE OF THE TOTAL ENVIRONMENT
·
2023
·
IF 9.8
Zhishuang Yang,Tianjing Lan,Hongyan Luo,Pei Li,Mingshu Wang,Renyong Jia,Shun Chen,Mafeng Liu,Xinxin Zhao,Qiao Yang,Ying Wu,Shaqiu Zhang,Juan Huang,Xumin Ou,Sai Mao,Qun Gao,Di Sun,Bin Tian,Anchun Cheng,Dekang Zhu
Antimicrobial resistance remains an utmost concern in human and veterinary medicine, impacting humans, animals, and the environment while significantly influencing the principles of One Health. While Riemerella anatipestifer ( R. anatipestifer ) is recognized as a waterfowl pathogen with multidrug-resistant properties, the specifics of its lincosamide resistance mechanism are inadequately understood. In this study, we identified a novel lincosamide resistance gene, lnu (I), in R. anatipestifer RCAD0121, and investigated its potential origin, transfer mechanisms, and dissemination status through genomic epidemiology. This exhibited 74.80 % amino acid identity with a previously reported gene, lnu (H). PCR analysis revealed lnu (I) prevalence in at least 44 R. anatipestifer isolates collected from multiple provinces in China. Furthermore, genomic mining unveiled 56 lnu (I) sequences within publicly available databases, primarily originating from environmental sources. In addition, members of the family Flavobacteriaceae were the dominant (16/56, 28.57 %) bacteria carrying the lnu (I) gene, with Flavobacterium exhibiting a similar GC content as lnu (I). Notably, specific instances of the lnu (I) gene were linked to mobile genetic elements within human and animal pathogenic bacteria. These findings suggest that Flavobacterium species within the environment could serve as potential ancestral sources of the novel lnu (I) gene, which has undergone mobilization events toward pathogenic bacteria.
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DALTON TRANSACTIONS
·
2023
·
IF 4
Shuang Wang,Mengjie Yao,Yuye Cheng,Kai Ding,Minghao Dou,Hongyu Shao,Shuaitong Xue,Shenjie Li,Yanyan Chen
By providing the spatial separation of the active sites and retaining high oxidative and reducing capacity, the direct Z-scheme heterostructure is considered the most potential structure for yielding photo-electric response. However, challenges still exist in the directional transfer of charge carriers between two semiconductors in direct Z-scheme structures. In this regard, by constructing the Vzn defect and p–n junction, a direct Z-scheme ZnxCd1−xS@ZnS-NiS heterostructure was obtained for the regulated electronic structure, which ensured high-yield hydrogen properties. The Zn vacancy in the partially-coated ZnS shell led to the Vzn energy level, and the addition of NiS led to the p–n structure, which caused a drastic downshift of the band edge potentials in comparison to that of pristine CdS. This variation gave rise to a staggered band edge alignment between ZnxCd1−xS and NiS, resulting in the variation of charge transfer kinetics from type-I to direct Z-scheme. Through careful characterization, it was found that the optimal photocatalytic hydrogen precipitation activity reached 16 683.6 μmol g−1 h−1, which was 70 times that of CdS, and this improvement was considered to form a spatial barrier, providing a clear direction and path for carrier transmission.
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JOURNAL OF ORGANOMETALLIC CHEMISTRY
·
2023
·
IF 2.3
Yi-Fan Tan,Guang-Min Liang,Kun Zhou,Jiu-Yu Ji,Li-Ping Zhao
A new three-dimensional (3D) supramolecular compound, [Ag(dppe)(CF 3 COO)] n ( 1 ), was prepared by using Ag(I) as the silver source and dppe as the organic ligand through the self-assembly approach. The bridging dppe ligand makes compound 1 appear as a one-dimensional (1D) wavy chain consolidated by the intramolecular hydrogen bonds. Two adjacent 1D chains are expanded to a two-dimensional (2D) layer passing through the intermolecular C H···π interaction between the dppe ligands, and the 2D layers further weave into a 3D supramolecular structure via another intermolecular C H···π interactions between the dppe ligands. The precise structure of 1 was determined by single crystal X-ray diffractometer (SCXRD), and it was well-characterized by Fourier transform infrared spectroscopy (FT-IR), nuclear magnetic resonance (NMR) spectroscopy, powder X-ray diffraction (PXRD), thermogravimetric analysis (TG) and differential thermogravimetry analysis (DTG), and UV–vis diffuse reflectance spectrum. In addition, the photocurrent response, electrochemistry characteristic and photodegradation of 1 were investigated. The degradation efficiency (82 %) of 1 as catalyst to degrade methylene blue (MB) was significantly higher than that without catalyst.
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