TALANTA
·
2017
·
IF 4.162
Quanqing Zhang,Yuanyu Huang,Haofan Sun,Yangyang Gan,Huali Shen,Bin Jia,Pengyuan Yang
Novel 3-D floor-like ordered mesoporous carbon functionalized graphene composites, FLOMC-GO, with high graphitized carbon contents were successfully synthesized using a soft template method. The one-pot sol-gel method was employed to prepare the silica soft template. Then, the sandwich-like composites were further combined together to form a 3-D structure through pre-carbonization and carbonization . During these procedures, the sulphonyl and sulfide bridges were formed by cross-linking processes to connect the phenyl rings. The prepared FLOMC-GO was confirmed to have a large pore volume (1.03 cm 3 g −1 ), high BET surface area (544.99 m 2 g −1 ) and well-ordered mesoporous structure with a narrow pore-size concentrated at 3.74 nm. The content of carbon reached 80% and was highly graphitized. By taking advantage of the interactions between carbon and glycans, FLOMC-GO was utilized to enrich N-linked glycans from OVA and human serum. As expected, excellent size-exclusion was found during the enrichment of N-glycans released from OVA, and 25 N-linked glycans were identified. The intensity of glycans enriched by FLOMC-GO was 7 times to the result of active carbon, while the ratio of OVA digestion to BSA interfering proteins increased to 1:50. Additionally, 31 N-linked glycans in total were enriched from human serum. The relatively easy synthesis as well as ability to enrich N-linked glycans with high selectivity and efficiency makes FLOMC-GO a promising adsorbent material for the discovery of human serum biomarkers for disease diagnosis.
研究领域:
生物材料学
·
糖组学
·
分子诊断
·
纳米医学
·
生物分离技术
✓ 已验证
DOI
高影响因子
Materials Research Express
·
2022
·Vol. 9
·期 9
·095001
·
IF 2.025
Wanshu Yan,Pingping Hu,Yiguo Jiang,Xiuquan Xu,Xianfeng Ma,Mengru Wang,Xinyue Bao
Photocatalytic inactivation has been proved to be an effective strategy to eliminate pathogenic bacteria in water. Herein, a novel 0D/2D p-n heterojunction of Ag2S-anchored P-doped g-C3N4 (Ag2S/PCN) were constructed by a simple two-step process coupling one-pot calcination and ultrasonic-assisted synthesis. The photocatalytic performance of as-prepared Ag2S/PCN composites was investigated by inactivating multidrug-resistant E. coli under visible light irradiation. The results indicated that Ag2S/PCN-5 possessed outstanding photocatalytic inactivation activity and superior stability, which could completely inactivate 7.0 log E. coli cells within 60 min. The enhanced photocatalytic activity of Ag2S/PCN-5 was mainly attributed to the elevated visible-light response and improved production and transfer of photoexcited charges. In addition, the free radicals trapping experiments results revealed that h+ and •O2− were predominantly responsible for the efficient inactivation activity. Finally, according to the 0D/2D structure and energy band configuration analysis, the enhanced p-n type heterojunction photocatalytic inactivation mechanism of Ag2S/PCN was discussed in detail.
研究领域:
环境科学
·
微生物学
·
材料科学
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DOI
高影响因子
Advanced Sustainable Systems
·
2022
·Vol. 6
·期 3
·2100380
·
IF 6.737
Zhengyi Li,Hu Li,Song Yang
Catalytic upgrading of CO 2 into value-added chemicals to build the excess carbon cycle is of great significance. In this work, carboxylate-functionalized zeolitic imidazolate framework (F-ZIF-90) with good crystallinity and porosity is constructed from ZIF-90 and employed as a robust heterogeneous catalyst to boost the reductive N -functionalization of various amines with CO 2 to furnish N -formyl compounds (up to 99% yield) in the presence of PhSiH 3 under an ambient environment. The imidazole carboxylate species ( COO - ) can not only activate hydrosilane and CO 2 to form the key intermediate formoxysliane but also activate amines to participate in the N -formylation reaction to obtain the target product. Moreover, it can enhance the catalyst capture and exchange ability toward ambient CO 2 . The powerful adsorption capacity of the F-ZIF-90 catalyst toward CO 2 is conducive to elevating CO 2 concentration around the active species. Theoretical calculations show that the carboxylate-mediated conversion path undergoes the transition state of hydrosilane activation with a relatively lower energy barrier (Δ G = 26.9 kcal mol –1 ). F-ZIF-90 exhibits good thermochemical stability with no obvious activity attenuation after repeated use 5 times. This strategy opens a new avenue based on ZIFs to develop heterogeneous catalysts for reductive upgrading of CO 2 .
研究领域:
催化
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材料科学
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化学工程
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环境化学
✓ 已验证
DOI
高影响因子
International Journal of Applied Mechanics
·
2024
·
IF 2.9
Shahao Li,Yang Chen,Xiaofeng Li,Hongyan Yang,Mengze Lu,Wei Zhang,Chuanxia Jiang,Shuming Cui,Junkai Liang,Liqun Tang,Taolin Sun
Recently, vitrimers with a reversible N → B coordination dynamic structure have garnered interest not only for their self-healing and reprocessable properties but also for their hydrolytic stability. Reported vitrimers with N → B internal coordination dynamic structure were excessively rigid, limiting their stretchability and toughness. This study synthesized a cross-linking agent (DNCB) with a cyclic nitrogen-boron coordination structure. This agent was then used in copolymerization with n-butyl acrylate (BA) and 4-vinylphenylboronic acid (BOH) to create soft vitrimers. By systematically tuning the composition, soft vitrimers exhibit water resistance along with high viscoelasticity, stretchability, toughness, and adhesive properties against various substrates. The observed mechanical behavior is attributed to the rapid relaxation of N → B coordination bonds and slow relaxation of B-O bonds in boroxine within the polymer network. It is anticipated that these soft vitrimers will be applied in adhesives, flexible electronics, and soft robotics due to their favorable properties.
研究领域:
材料科学
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高分子化学
·
软物质物理
·
胶粘剂技术
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柔性电子学
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机器人学
✓ 已验证
DOI
高影响因子
JOURNAL OF POLYMER RESEARCH
·
2017
·Vol. 25
·期 1
·1-12
·
IF 1.615
Li Yuesheng,Qin Jiangtao,Bao Huaxi,Han Yan,Zeng Xianglin,Zheng Hua,Huang Yaqiong,Xia Xiangxiang,Dong Zhibing,Hu Renhuo,Liu Yi
As a temperature-sensitive-discoloration hydrogel based on NIPAAm/HHPC was fabricated via two steps of electron beam radiation. Small nanomaterial such as GO and Fe 2 O 3 were also added severally into the system of hydrogel as chromogenic agent. Different colors can be displayed in nanocomposite hydrogel system at the low, medium and high temperature respectively. The LCST of hydrogel system can be also adjusted precisely by the changes of irradiation dose of the prepolymer and composition ratio. Experimental results showed that the hydrogel can be changed quickly itself color in its near LCST. The microstructure and composition of nanocomposite hydrogel were characterized further by NMR, FTIR, TG, DSC, XRD, FE-SEM and XPS so as to reveal the mechanism of temperature-sensitive- discoloration. The novel NIPAAm/HHPC-based nanocomposite hydrogel is suitable especially to indicate different fever temperatures for fever patients and can be expected to as a new type of temperature-sensitive sensor and replace the traditional clinical thermometer.
( A ) SEM images of different hydrogels (previous row). ( B ) The reversible temperature-sensitive-discoloration process of different hydrogels ( bottom left ). ( C ) DSC thermograms of different hydrogels ( bottom right ).
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
·
2020
·Vol. 31
·期 8
·1-9
·
IF 2.489
Li Wan,Hu Xueying,Chen Jiawei,Wei Zhengnan,Song Chengwu,Huang Rongzeng
The intrinsic fragility of hydroxyapatite (HAP) restricts its wider applications for local delivery of antibiotics. The composites formed by integrating HAP with hydrogels can improve the properties of HAP. However, these reported composites not only require tedious preparation and employ organic solvent and toxic reagents, but also hardly have inherent antimicrobial property. In this study, N-(9-Fluorenylmethoxycarbonyl)-L-Phenylalanine/nano-hydroxyapatite (Fmoc-L-Phe/nHAP) hybrid supramolecular hydrogels with antibacterial property and cytocompatibility was prepared by integrating nHAP as reinforcement with Fmoc-L-Phe supramolecular hydrogels. The results showed that nHAP bounds in the chamber of the gel network and adheres to the fiber of Fmoc-L-Phe due to intermolecular interaction, remarkably improving the mechanical strength of Fmoc-L-Phe supramolecular hydrogels. The results of inhibition zone experiment and MTT experiment showed that the Fmoc-L-Phe/nHAP hybrid supramolecular hydrogels possess antimicrobial property and cytocompatibility. In vitro release experiment of chlorogenic acid (CGA) from the hybrid supramolecular hydrogels was performed. The study of the release kinetics indicated that the release behavior of CGA from the hybrid supramolecular hydrogels is following Weibull model and release mechanism involved Fickian diffusion and erosion of the surface of hydrogel matrix. The release of CGA shows a good inhibition effect on S. aureus . The results show that the Fmoc-L-Phe/nHAP hybrid hydrogels with antibacterial property and cytocompatibility have promising applications as drug delivery carrier.
Due to the intrinsic fragility of hydroxyapatite (HAP), the properties of HAP could be improved by incorporation into hydrogels. However, these reported composites not only require tedious preparation and employ organic solvent and toxic reagents, but also hardly have inherent antimicrobial property. We prepared N-(9-Fluorenylmethoxycarbonyl)-L-Phenylalanine/nano-hydroxyapatite (Fmoc-L-Phe/nHAP) hybrid supramolecular hydrogels by integrating nHAP as reinforcement with Fmoc-L-Phe supramolecular hydrogels. The results showed that nHAP bounds in the chamber of the gel network and adheres to the fiber of Fmoc-L-Phe due to intermolecular interaction, remarkably improving the mechanical strength of Fmoc-L-Phe supramolecular hydrogels. The results of inhibition zone experiment and MTT experiment showed that the Fmoc-L-Phe/nHAP hybrid supramolecular hydrogels possess antibacterial property and cytocompatibility. In vitro release experiment of chlorogenic acid (CGA) from the hybrid supramolecular hydrogels was performed. The study of the release kinetics indicated that the release behavior of CGA from the hybrid supramolecular hydrogels is following Weibull model and release mechanism involved Fickian diffusion and erosion of the surface of hydrogel matrix. The release of CGA shows a good inhibition effect on S. aureus . The results show that the Fmoc-L-Phe/nHAP hybrid hydrogels with antibacterial property and cytocompatibility have promising applications as drug delivery carrier.
研究领域:
材料科学
·
生物医学工程
·
药学
✓ 已验证
DOI
高影响因子
FISH & SHELLFISH IMMUNOLOGY
·
2016
·
IF 3.025
Shiwei Xie,Weiwen Zhou,Lixia Tian,Jin Niu,Yongjian Liu
An 8-week feeding trial was conducted to evaluate the effect of N -acetyl cysteine (NAC) and glycine supplementation on growth performance, glutathione (GSH) synthesis, anti-oxidative and immune ability of Nile tilapia , Oreochromis niloticus . Four practical diets were formulated, control, control +0.2% NAC, control +0.5% glycine, control +0.2% NAC +0.5% glycine. Each diet was randomly assigned to quadruplicate groups of 30 fish (approximately 9.5 g). The weight gain and specific growth rate were significantly increased with the supplementation of NAC and glycine. While they had no effect on feed efficiency feed intake and survival. Glutathion peroxidase (GPx) was increased by NAC and γ-glutamine cysteine synthase (γ-GCS) in plasma were increased by glycine. After the feeding trail, fish were challenged by Streptococcus iniae , fish fed the diet supplemented with NAC obtained significantly higher survival rate after 72 h challenge test. NAC also decreased malonaldehyde (MDA) in liver, increased glutathione S-transferase (GST) activity in plasma, up-regulated mRNA expression of Superoxide dismutase (SOD) and GPx in liver and headkidney. Dietary supplementation of glycine increased the anti-oxidative ability of tilapia through increase anti-oxidative enzyme activity (SOD, glutathione reductase , myeloperoxidase) and up-regulate anti-oxidative gene expression (SOD). Immune ability only enhanced by the supplementation of NAC through increased interleukin-1β (IL-1β) mRNA expression. These results clearly indicated that the supplementation of NAC and glycine can significantly improve the growth performance of tilapia, and NAC also enhance the anti-oxidative and immune capacity of tilapia, glycine could only enhance the anti-oxidative ability.
研究领域:
水产养殖
·
营养学
·
免疫学
·
生物化学
✓ 已验证
DOI
PubMed
高影响因子
iScience
·
2023
·
IF 5.8
Jiancheng Zhao,Christian Marcus Pedersen,Honghong Chang,Xianglin Hou,Yingxiong Wang,Yan Qiao
Herein, we report choline chloride-based deep eutectic solvents (DESs) promoted conversion of N -acetyl- d -glucosamine (GlcNAc) into nitrogen-containing compounds, i.e., 3-acetamido-5-(1′,2′-dihydroxyethyl) furan (Chromogen III) and 3-acetamido-5-acetylfuran (3A5AF). The binary deep eutectic solvent choline chloride-glycerin (ChCl-Gly), was found to promote the dehydration of GlcNAc to form Chromogen III, which reaches a maximum yield of 31.1%. On the other hand, the ternary deep eutectic solvent, choline chloride-glycerol-B(OH) 3 (ChCl-Gly-B(OH) 3 ), promoted the further dehydration of GlcNAc into 3A5AF with a maximum yield of 39.2%. In addition, the reaction intermediate, 2-acetamido-2,3-dideoxy- d - erythro -hex-2-enofuranose (Chromogen I), was detected by in situ nuclear magnetic resonance (NMR) techniques when promoted by ChCl-Gly-B(OH) 3 . The experimental results of the 1 H NMR chemical shift titration showed ChCl-Gly interactions with α-OH-3 and α-OH-4 of GlcNAc, which is responsible for promoting the dehydration reaction. Meanwhile, the strong interaction between Cl − and GlcNAc was demonstrated by 35 Cl NMR.
研究领域:
化学工程
·
有机化学
·
催化
·
可持续化学
✓ 已验证
DOI
PubMed
高影响因子
TETRAHEDRON-ASYMMETRY
·
2010
·
IF 2.625
Zhen-Wei Zhang,Gui Lu,Miao-Miao Chen,Ning Lin,Yong-Bo Li,Tamio Hayashi,Albert S.C. Chan
The first asymmetric Mannich-type reaction of methyl isocyanoacetate with N -sulfonylimines catalyzed by cinchona alkaloid derivatives yielded 2-imidazolines with high diastereoselectivities and good enantioselectivities (up to >99:1 dr and 70% ee). This reaction provided a convenient route to access various substituted 2-imidazoline-4-carboxylates and related α,β-diamino acids in high enantiomeric purities.
研究领域:
有机化学
·
药物化学
·
不对称合成
·
催化化学
·
生物有机化学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2020
·Vol. 10
·期 44
·26142-26150
·
IF 3.119
Binyu Xu,Samuthirarajan Senthilkumar,Wei Zhong,Zhongquan Shen,Chunxin Lu,Xiaoming Liu
In this work, core–shell Fe3O4@Cu2O and Fe3O4@Cu2O–Cu nanomaterials for aerobic oxidation of benzylic alcohols are reported with 2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPO) and N-methylimidazole (NMI) as the co-catalysts. To anchor Cu2O nanoparticles around the magnetic particles under solvothermal conditions, the magnetic material Fe3O4 was modified by grafting a layer of L-lysine (L-Lys) to introduce –NH2 groups at the surface of the magnetic particles. With amine groups as the anchor, Cu(NO3)2 was used to co-precipitate the desired Cu2O by using ethylene glycol as the reducing agent. Prolonging the reaction time would lead to over-reduced forms of the magnetic materials in the presence of copper, Fe3O4@Cu2O–Cu. The nanomaterials and its precursors were fully characterized by a variety of spectroscopic techniques. In combination with both TEMPO and NMI, these materials showed excellent catalytic activities in aerobic oxidation of benzylic alcohols under ambient conditions. For most of the benzylic alcohols, the conversion into aldehydes was nearly quantitative with aldehydes as the sole product. The materials were recyclable and robust. Up to 7 repeat runs, its activity dropped less than 10%. The over-reduced materials, Fe3O4@Cu2O–Cu, exhibited slightly better performance in durability. The magnetic properties allowed easy separation after reaction by simply applying an external magnet.
研究领域:
材料科学
·
催化
·
化学工程
·
纳米技术
✓ 已验证
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Yuanliang Gu,Zinan Zhang,Shengshen Gu,Qi Zhang,Meng Guo,Yang Pan,Genghao Gong,Zhaoliang Cui,Xiuxiu Ren,Jing Zhong
1,2-bis(triethoxysilyl)ethane (BTESE)-derived organosilica membranes have good acid-resistant stability in the application of acetic acid dehydration via pervaporation technology. To enhance the separation performance of water (0.26 nm) and acetic acid (0.43 nm), graphitic carbon nitride (g-C 3 N 4 ) distinguished by its periodic nanoporosity (0.31-0.34 nm) and hydrophilic functionality, offers exceptional potential for organosilica-based membranes improvement. Herein, we tailored g-C 3 N 4 nanostructures as 2D nanosheets (4 nm thickness) and 0D quantum dots (4 nm diameter), and embedded them into BTESE membranes. For their thermal stability, the nanosheets enhanced structural integrity due to interlayer covalent/hydrogen bonding networks, while quantum dots exhibited a larger weight loss but preserved more residues at 800 o C. Nanosheets incorporated BTESE/g-C 3 N 4 composites reduced BTESE pore size, amplified surface hydrophilicity and membrane thickness, whereas quantum dots with abundant functional groups minimally altered BTESE matrix structures. In pervaporation of acetic acid/water, BTESE performance was improved by both morphologies of g-C 3 N 4 fillers at the same optimal loading. The nanosheet-incorporated membrane (BTESE/CN-NSs-3) achieved a separation factor of 2327 with a flux of 2.35 kg/m 2 ·h, while quantum dots-incorporated membrane (BTESE/CN-QDs-3) exhibited a higher flux of 2.52 kg/m 2 ·h but a lower separation factor of 1352. In feed concentration (50–90 wt% AcOH) and temperature dependent (55–95 °C) operations, nanosheets facilitated molecule sieving through interlayer channels, whereas quantum dots enabled lower-resistance pathways by diffusivity dominated permeation. This work establishes g-C 3 N 4 dimensionality modulating organosilica membrane’s transport hierarchy, providing a selection for developing acid-resistant membranes in improving flux and separation factor.
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF ENERGY RESEARCH
·
2022
·Vol. 46
·期 11
·15174-15181
·
IF 4.672
Yang Liu,Xuesong Cai,Dinggui Chen,Yan Qin,Yuan Chen,Jinxiang Chen,Chenglu Liang
Summary The large-scale applications of energy storage system via lithium-ion batteries (LIBs) put forward demands for high capacity, high safety, and low cost of materials. Covalent organic polymers have attracted extensive attention because of their high capacity, flexible structural design, high safety, abundance, and low cost. Here, 2,3,5,6-tetraamino-p-benzoquinone and hexaketocyclohexane octahydrate were chosen as monomers to construct the covalent organic framework (TH-COF) cathode materials with active C=O and C=N groups. The TH-COF was further composed with reduced graphene oxide (rGO) and the prepared TH-COF/rGO cathode provided a capacity of 135 mAh g −1 after 600 cycles at 1 C current density. In addition, after 100 cycles, the cathode delivered capacities of 118 and 73 mAh g −1 at the high current densities of 5 C and 20 C, respectively, displaying superior rate performances. The TH-COF/rGO electrode exhibited high capacity and stability, making it a promising cathode material for the next generation LIBs.
研究领域:
材料科学
·
能量存储
·
电化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）