ACS Applied Polymer Materials
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2025
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IF 4.7
Yingqi Wei,Hao Wang,Yaxi Zhu,Guancheng Zhan,Lihuan Zhang,Huichang Gao,Longyang Jin,Ruobing Feng
Peripheral nerve injury frequently occurs alongside vascular injury due to the incorporation of vascular tissue within the nerve bundle. During the repair process of peripheral nerve injuries, the concurrent regeneration of capillaries within the nerve bundles is crucial for facilitating nerve regeneration. However, current studies often overlook the regeneration of blood vessels in nerve bundles when designing nerve repair scaffolds, leading to suboptimal nerve regeneration outcomes. To address this limitation, amino-modified Cu-doped mesoporous bioactive glass (Cu-MBG) was developed as a nanodelivery carrier for miR-29a to construct miR-29a@Cu-MBG nanoparticles, which exhibit dual functionality in promoting nerve regeneration and inducing vascular regeneration. Subsequently, miR-29a@Cu-MBG was incorporated into a CS/GelMA hydrogel to create an engineered multifunctional nerve conduit through the ionic cross-linking of chitosan and the optical cross-linking of GelMA, which demonstrated excellent mechanical properties and biocompatibility. In vitro cell experiments indicated that the sustained release of miR-29a@Cu-MBG from the conduit effectively delivered miR-29a into PC12 cells, leading to the upregulation of nerve regeneration-associated genes (GAP-43 and NF-200) and the outgrowth of neurite. Additionally, Cu-MBG was found to enhance the migration of HUVECs and upregulate genes related to angiogenesis (HIF-α, ANG, eNOS, and KDR), promoting the tube formation of HUVECs. These findings offer a perspective for the design of nerve conduits capable of promoting both nerve and vascular regeneration.
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高影响因子
MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 5
·1-9
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IF 5.3
Li Rui,Que Wenzhong,Han Haiyan,Shi Honghui,Wang Rongfeng,Qiu Bin
IL-17 (interleukin-17) is a common proinflammatory cytokine and can be adopted as an important biomarker for several diseases; it is thus very necessary to design an effective method for monitoring IL-17. Herein, by preparing silver nanoparticles/graphdiyne (Ag/GDY) with simple electroless deposition as the sensing platform and methylene blue/UiO-66-NH 2 MOFs (MB/MOFs) as the signaling-amplifier, a highly efficient sandwich-like electrochemical immunosensing (SLEI) platform was designed for IL-17 detection. The superior electrical property, easy preparation, large surface area, and high stability of Ag/GDY make it a desirable substrate to immobilize primary antibody of IL-17. Meanwhile, the unique structure of UiO-66-NH 2 is beneficial to immobilize MB probe and secondary antibody. By optimizing experimental conditions, the MB current obtained at the as-designed SLEI platform increases along with IL-17 increase, and the related linearity is 1.0 pg mL −1 –1.0 ng mL −1 coupled with a low detection limit of 0.3 pg mL −1 . It is expected that the SLEI platform based on Ag/GDY and MB/MOFs shows some potential application for IL-17 detection. Graphical abstract
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高影响因子
ENVIRONMENTAL RESEARCH
·
2024
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IF 7.7
Ya Jiao,Xian Li,Guohao Cheng,Jingfan Chen,Li Wang,Yongli Liu,Guifen Zhu
Metal–organic frameworks (MOFs) are used as novel adsorption materials owing to their large surface area and tunable pore size. However, the lack of selectivity considerably limits their application. Consequently, designing functionalized MOFs with specific recognition abilities is essential for enhancing their adsorption performance. Herein, we synthesized a functionalized NH 2 -UiO-66 composite modified by molecularly imprinted polymers (MIP@NH 2 -UiO-66) via a one-step polymerization process in which NH 2 -UiO-66 and MIP were formed simultaneously. Results demonstrate that MIP@NH 2 -UiO-66 effectively recognized sulfamethoxazole (SMX) in complex matrices. The adsorption equilibrium was reached in only 30 min, and this fast SMX adsorption on MIP@NH 2 -UiO-66 was described by the Avrami kinetic model, which indicates a spontaneous and exothermic adsorption process. Within the pH range of 3.0–10.0, MIP@NH 2 -UiO-66 exhibited an optimal binding capacity for SMX, and the maximum adsorption of SMX was 68.36 mg g −1 at 25°C, which exceeded those of existing adsorption materials (< 60.10 mg g −1 ). Additionally, MIP@NH 2 -UiO-66 was regenerated for ∼17 cycles compared to less than eight cycles for the other adsorbents. MIP@NH 2 -UiO-66 effectively removed 90.58%–99.60% of SMX from river water, rainwater, soil, sediment, chicken, pork, and milk samples, with a relative standard deviation of less than 4.43%. The superior adsorption of SMX on MIP@NH 2 -UiO-66 was primarily driven by the synergistic effects of the imprinting sites, hydrogen bonding, and electrostatic forces. The one-step polymerization method substantially simplified the synthesis process and reduced the costs, which are promising factors for the synthesis of MOFs with high selectivity.
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高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2025
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IF 8.3
Jun-Qing Ye,Bin Cheng,Yunfei Bu,Jun-Feng Qian,Qian Liang,Ming-Yang He,Qun Chen
The development of high-efficiency photocatalysts for water splitting to hydrogen (H 2 ) is crucial for alleviating energy crisis and environmental problems. In this study, a novel type-II ternary heterojunction photocatalyst, CDs/NH 2 -MIL-125 (Ti)/Cu 2 O, was fabricated through the integration of NH 2 -MIL-125 (Ti) with Cu 2 O and carbon dots (CDs), exhibited excellent photocatalytic H 2 production rate of 12817.1 μmol/g/h with apparent quantum efficiency (AQE) of 17.13 % under visible light irradiation. Characterization revealed a uniform and dense structural integration with a high Brunauer-Emmett-Teller (BET) surface area of 275.9 m 2 g −1 and a suitable energy band gap of 2.18 eV. Furthermore, the heterostructures promoted efficient photo-generated carrier separation and enhanced reduction capabilities . Notably, CDs, serving as cocatalysts or electron acceptors, improved visible light utilization and electron migration, significantly boosting H 2 production. Insights from electron spin resonance (ESR) and density functional theory (DFT) calculations supported the migration mechanisms of electrons. This work presents a significant advance in photocatalytic technology for sustainable energy by designing high-performance CDs-modified heterojunction photocatalysts.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Jing Meng,Moustafa Zahran,Ahmed S. Abou-Elyazed,Xiaolin Li
Herein, we report a novel electrochemical sensor for determining glucose in sweat, employing a graphene/metal–organic framework (MOF) as a modifier for stainless steel (SS) electrode. The MOF structures, MIL-101(Cr), MIL-101(Cr)-NO 2 , and MIL-101(Cr)-NH 2 , were hydrothermally synthesized and then characterized using X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, N 2 adsorption/desorption isotherms, and scanning electron microscopy (SEM). XRD and SEM results proved the formation of the crystalline MIL-101(Cr) and MIL-101(Cr)-NO 2 , and the amorphous MIL-101(Cr)-NH 2 . Additionally, FT-IR and isotherms confirmed their composition and mesoporosity, respectively. The amorphous MIL-101(Cr)-NH 2 showed the best electrocatalytic activity towards glucose oxidation among the fabricated MOFs. The electrocatalytic activity was also boosted after incorporating conductive graphene. Under optimized conditions, graphene/MIL-101(Cr)-NH 2 /SS was used for glucose determination using square wave voltammetry and chronoamperometry with detection limits of 0.004 and 0.01 mM, respectively. Moreover, the modified electrode showed acceptable recovery values when it was applied to detect glucose in artificial sweat samples.
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高影响因子
DESALINATION
·
2025
·
IF 9.8
Xinyue Zhang,Shichen Xiao,Zerong Miao,Xudong Wang,Jin Wang,Jiajin Hao,Junwei Xin,Huihui Zhang,Lei Wang
The selective recovery of lithium from salt-lake brines using functionalized polyamide nanofiltration (NF) membranes offers a promising strategy to alleviate the global lithium resource shortage. However, the structural controllability of functional fillers and their interfacial compatibility remain critical challenges in constructing high-performance NF membranes. In this study, a polyamide NF membrane was modified with defect-engineered and gel-state UiO-66-NH 2 nanoparticles, combined with an external electric field, to achieve efficient Li + /Mg 2+ separation. By tuning the HCl/HAc ratio, the nucleation and growth of UiO-66-NH 2 were regulated, yielding gel-state nanoparticles with abundant defects (defect coordination number ~ 0.73), excellent dispersibility, and high protonation, facilitating interfacial integration with the polyamide matrix. In situ characterization revealed that defect-engineered and gel-state UiO-66-NH 2 enhanced the membrane's positive surface charge and formed a “spinal-like” microstructure. Under the optimal acid ratio, the nanoparticles promoted higher polyamide cross-linking, reducing the average effective pore size from 0.54 to 0.46 nm, enabling synergistic control of both physical and chemical membrane properties. With an applied electric field, monovalent ion dehydration and migration were accelerated, enhancing ion decoupling and achieving a separation factor of 83.87 for Li + /Mg 2+ at an applied current of 6 mA. This work demonstrates a triple synergistic mechanism involving interface regulation, structural optimization, and electric-field coupling, highlighting the pivotal role of gel-state defect-engineered MOFs in tuning membrane microstructure and surface charge. This finding provides new theoretical guidance and design strategies for efficient lithium recovery using electric-field assisted functional nanofiber membranes.
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CHEMICAL ENGINEERING JOURNAL
·
2025
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IF 13.2
Yongxin Guo,Jiaoyang Ji,Gang Wang,Sitong Zhang,Yong Yu
Microplastics (MPs) pollution and freshwater scarcity have emerged as one of the most severe global environmental crises, while conventional removal methods often suffer from inefficiency and secondary pollution. Here we developed an interfacial solar evaporator composed of a functional pectin-NH 2 /sorghum stalk (PUS) hydrogel for simultaneous freshwater production and MPs removal. The PUS system achieved evaporation rates of 3.48 ± 0.15 and 3.29 ± 0.07 kg·m −2 ·h −1 in realistic seawater and influent wastewater, respectively. Notably, flow cytometry and in-situ Raman analysis confirmed the effective removal of MPs in seawater (90.24 %) and wastewater (87.14 %). Further long-term experiments (30 d) exhibited evaporation rates of 19.45 ± 1.61 and 19.19 ± 1.43 kg m −2 ·d −1 in seawater and wastewater, respectively. Density functional theory (DFT) and molecular dynamics (MD) simulations identified that van der Waals interactions and hydrogen bonding (NH…O=C and NH…O–C) synergistically govern MPs capture and PUS structural stabilization. Techno-economic analysis (TEA) confirmed a competitive freshwater production cost of 0.12 USD/kg, underscoring the feasibility of large-scale MPs-removing solar evaporation technique. This study reveals the industrial potential of natural functional polysaccharide hydrogels and lignocellulose in freshwater production and deeps the adsorption mechanisms of functional pectin with MPs, which provides new strategies to remove MPs and produce fresh water.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2025
·
IF 2.8
Ke Liu,Qisong Liu,Rui Fan,Hongfa Huang,Hua Yi,Chao Hu
Mixed matrix membranes (MMMs) incorporating metal–organic frameworks (MOFs) as fillers show attractive selectivity and permeability for gas separation. However, the performance improvement is restricted by undesirable interfacial interaction and inhomogeneous dispersion of MOFs in the membrane matrix. In this paper, amino-functionalized UIO-66 (U6N) with high porosity was employed as a filler and further regulated by a controlled plant polyphenol-induced surface modification strategy. The process involved the formation of tannic acid-iron(III) complex (TA-Fe(III)) on the U6N surface, which improved interfacial compatibility with the polyimide matrix while introducing abundant hydroxyl groups to enhance gas transport properties. Accordingly, the modified MMMs containing 30 wt.% U6N@TA-Fe(III) achieved optimized gas separation performance. Specifically, the CO 2 permeability increased to about 2495.9 Barrer with a CO 2 /CH 4 selectivity of 19.32, which exceeded the 2008 Robeson upper limit and showed an increase of 22.1% and 25.6%, respectively, compared to the MMMs embedded with unmodified U6N. Moreover, the improved dispersion of the U6N@TA-Fe(III) within the membrane structure is conducive to improving separation performance for CO 2 /N 2 and O 2 /N 2 . Therefore, this work provides a novel insight into the rational design of the MMMs via a facile modification strategy, which can further improve the gas separation performance of the MMMs.
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高影响因子
TOPICS IN CATALYSIS
·
2025
·
IF 3
Guan Yueyue,Zeng Xianglong,Liu Shuming,Yao Kai,Hu Zhenhui,Xiao Longhao,Fang Zheng,Yang Yongsheng,Liu Hongjun
To address the issue of limited degradation efficiency due to rapid carrier recombination in piezoelectric catalysis, this study designed a ternary heterojunction structure of ZnO/CuO@UiO-66-NH 2 . A ZnO/CuO heterointerface was constructed on the surface of UiO-66-NH 2 via a hydrothermal method, forming a composite piezoelectric catalytic system with abundant active sites and enhanced built-in electric fields. Theoretical analysis indicated that UiO-66-NH 2 , as a carrier, not only significantly increased the specific surface area of the material but also cooperatively regulated the charge distribution in the heterojunction region. Under ultrasonic vibration, the piezoelectric potential generated by the ZnO/CuO heterojunction effectively drove carrier separation, thereby significantly enhancing the redox reaction efficiency. Under dark conditions, the 30-minute degradation rate of RhB by this material reached 99.7%, with a rate constant of 0.09435 min⁻¹, far superior to the pure ZnO/CuO system. Additionally, ZnO/CuO@UiO-66-NH 2 demonstrated excellent catalytic performance and cycling stability in the degradation of methyl orange and methylene blue. Band structure and radical trapping experiments confirmed that hydrogen radicals (·H) and superoxide radicals (·O 2 ⁻) were the main active species in the degradation process. This research provides new material ideas for the development of efficient and stable heterojunction piezoelectric catalysts and offers potential pathways for the construction of integrated systems for dye wastewater treatment and energy conversion. Graphical
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高影响因子
LANGMUIR
·
2022
·
IF 4.331
Saijie Song,Minghui Wan,Wenli Feng,Yu Tian,Xuefeng Jiang,Yi Luo,Jian Shen
The stimuli responsive pesticide delivery system (PDS) has drawn increasing attention in recent years, a system which can effectively improve the utilization of pesticides. In the current research, we report a pH responsive PDS by using carboxymethyl cellulose (CMC) modified Zr-based metal organic frameworks (UiO-66-NH2) as the nanocarrier for acetamiprid (ATP). UiO-66-NH2-CMC possesses a large surface area and abundant pores, which can effectively load ATP, and the loading rate is as high as 90.79%. Compared with free ATP, the ATP@UiO-66-NH2-CMC nanopesticide exhibits pH responsive controlled release behavior, and the pesticide can sustained release to the medium. In addition, it also shows improved leaf affinity, which makes it easier to wet the leaf surface and improve the utilization of pesticide. Therefore, ATP@UiO-66-NH2-CMC displays better antipest activity against aphids than free ATP does. Meanwhile, ATP@UiO-66-NH2-CMC shows no negative effects on the germination and growth of maize, showing good biosafety. Moreover, the ATP@UiO-66-NH2-CMC nanopesticide does not contain any toxic organic solvents or additives. Therefore, we hope that it can be a suitable candidate for plant protection and sustainable agriculture.
研究领域:
农业科学
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材料科学
·
环境科学
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高影响因子
MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Fujian Xu,Jinyi Zhang,Xiaoliang Zeng,Zhou Long,Xiandeng Hou
Alkaline phosphatase (ALP) is now a well acknowledged indicator for diverse clinical diseases correlated with its abnormal expression. Compared to the assays by traditional and lately emerging methods, the fluorescent (FL) sensing, especially in the turn-on mode, has become more favored due to its simplicity, low cost, and high sensitivity and precision. However, the feasible FL probes are still limited and suffering from poor biological compatibility, complex preparation, additional modification or function-alization. Herein, we found that one common metal–organic framework, UiO-66-NH 2 at nanoscale, could act as a new and label-free FL probe for facile sensing of ALP in the turn-on mode, based on the simple aid by phenyl phosphate which could be hydro-lyzed by ALP, with the product of phosphate ion enhancing the FL emission of UiO-66-NH 2 via simple adsorption. Unlike many other FL probes in the turn-on mode, it was unnecessary to quench the FL of the probes in advance, greatly simplifying the sensor design. Moreover, by use of a new method based on dielectric barrier discharge (DBD), the UiO-66-NH 2 could be prepared in 10 min, much shorter than that (usually hours) for preparing most other FL probes for ALP assay. The limit of detection was 0.4 U L -1 , superior or at least rivalrous to the previously reported ones, and the ALP assay was also accomplished for real serum samples, with the analytical results highly consistent with those obtained by the clinical procedures, revealing its high practical utility.
研究领域:
分析化学
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生物传感器
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材料科学
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医学诊断
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高影响因子
Chemosensors
·
2026
·Vol. 14
·期 7
·156
·
IF 4.4
Tong Xiang,Chongyang Zhang,Qiongqiong Ren,Jinlong Chang,Linyan Xie,Xuming Sun
Nitrite (NO2−) is a crucial environmental and food safety indicator, and excessive intake poses severe threats to human health; thus, highly sensitive and selective detection methods are urgently needed. Herein, a ratiometric fluorescent nanosensor based on N-CDs@UiO-66-NH2was constructed via a facile assembly strategy for sensitive and selective nitrite detection. The composite demonstrated dual-emission fluorescence at 456 nm and 730 nm under 365 nm excitation, originating from UiO-66-NH2and N-CDs, respectively, enabling an intrinsic self-referencing signal. The fluorescence intensity ratio exhibited a good linear response toward nitrite in the range of 10–100 μM and 100–450 μM with a limit of detection (LOD) 1.76 μM. The nanosensor showed high selectivity and anti-interference ability against various ions and molecules. Furthermore, it was successfully applied to nitrite detection in lake water samples with satisfactory recoveries (97–101%) and low relative standard deviations (<1.8%). This work provides a simple and effective approach for nitrite monitoring in environmental samples.
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