Scientific Reports
·
2020
·Vol. 10
·期 1
·1-10
·
IF 3.998
Liu Shuanglin,Cheng Xiaodong,Li XiaoFei,Kong Yuanfang,Jiang Shiqing,Dong Chunhong,Wang Guoqing
Catalpol has gained increasing attention for its potential contributions in controlling glycolipid metabolism and diabetic complications, which makes used as a very promising scaffold for seeking new anti-diabetic drug candidates. Acylation derivatives of catalpol crotonate (CCs) were designed as drug ligands of glutathione peroxidase (GSH-Px) based on molecular docking (MD) using Surfex-Docking method. Catalpol hexacrotonate (CC-6) was synthesized using microwave assisted method and characterized by FT-IR, NMR, HPLC and HRMS. The MD results indicate that with the increasing of esterification degree of hydroxyl, the C log P of CCs increased significantly, and the calculated total scores (Total_score) of CCs are all higher than that of catalpol. It shows that CCs maybe served as potential lead compounds for neuroprotective agents. It was found that the maximum Total_score of isomers in one group CCs is often not that the molecule with minimum energy. MD calculations show that there are five hydrogen bonds formed between CC-6 and the surrounding amino acid residues. Molecular dynamics simulation results show that the binding of CC-6 with GSH-Px is stable. CC-6 was screened for SH-SY5Y cells viability by MTT (3-(4, 5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide) assay, the result indicates CC-6 can effectively reverse SZT induced cells apoptosis with dose-dependent manner, which can indirectly show that CC-6 is a potential neuroprotective agent.
研究领域:
药物化学
·
分子生物学
·
神经科学
✓ 已验证
DOI
PubMed
高影响因子
International Journal of Industrial Chemistry
·
2020
·Vol. 11
·期 2
·133-145
·
IF 0
Mpelwa Musa,Tang Shanfa,Jin Lijun
Mineral scale deposit is one of the major problems incessantly faced in the oil and gas producing wells and surface facilities, and if not well-handled can cause an unsuccessful petroleum production. To eradicate scale deposits, scale inhibitors (SIs) are commonly deployed into industrial water systems. Because of effectiveness and long squeeze lifetimes, organic phosphonate SIs are extensively used for preventing mineral scale formation in industrial water systems. However, they usually exhibit lower Ca 2+ and Mg 2+ tolerances that restrict their applications in harsh conditions where high inhibitory dosages are needed. In this paper, a multifunctional aminoalkylenephosphonate-based antiscalant having higher Ca 2+ and Mg 2+ tolerances is studied. The antiscalant was synthesized, characterized (FTIR and NMR spectroscopies), and evaluated in accordance with the NACE Standard Method (TM0374) for preventing CaSO 4 and CaCO 3 formation in the petroleum industry. The effects of inhibitory dosages, water hardness, temperature, incubation period, and pH were studied. We further tested the performance of the antiscalant in simulated field waters. Experimental results show that the multifunctional aminoalkylenephosphonate-based antiscalant has better inhibitory properties as compared to conventional aminoalkylenephosphonate-based SIs. The incorporation of the sulfonate group into the molecule significantly improved the solubility of the antiscalant and hence its tolerances to Ca 2+ and Mg 2+ ions. Also, it bolstered thermal stability of the inhibitor. The results from simulated field conditions are promising. The synthesized antiscalant performed superbly than the conventionally aminomethylenephosphonate antiscalants where Ca 2+ and Mg 2+ concentrations are challenging.
研究领域:
化学工程
·
石油工程
✓ 已验证
DOI
Frontiers of Materials Science
·
2015
·Vol. 10
·期 1
·73-79
·
IF 1
Gao Rui,Ge Wen-jun,Miao Shu,Zhang Tao,Wang Xian-ping,Fang Qian-feng
The grain morphology, nano-oxide particles and mechanical properties of oxide dispersion strengthened (ODS)-316L austenitic steel synthesized by electron beam selective melting (EBSM) technique with different post-working processes, were explored in this study. The ODS-316L austenitic steel with superfine nano-sized oxide particles of 30–40 nm exhibits good tensile strength (412 MPa) and large total elongation (about 51%) due to the pinning effect of uniform distributed oxide particles on dislocations. After hot rolling, the specimen exhibits a higher tensile strength of 482 MPa, but the elongation decreases to 31.8% owing to the introduction of high-density dislocations. The subsequent heat treatment eliminates the grain defects induced by hot rolling and increases the randomly orientated grains, which further improves the strength and ductility of EBSM ODS-316L steel.
研究领域:
材料科学
·
冶金工程
✓ 已验证
DOI
高影响因子
Chemical and Biological Technologies in Agriculture
·
2023
·Vol. 10
·期 1
·1-14
·
IF 6.6
Zhou Shiyang,Huang Gangliang
In recent years, the biological activity of plant polysaccharides has attracted more and more attention. Juglans regia was one of the four-dry fruits in the world, it has very high value in nutrition and health care value was very high. To better develop the nutritional and health effects of the J. regia shell polysaccharide, J. regia shell was used as raw material to prepare polysaccharide by the water extraction and alcohol precipitation method. The molecular weight, monosaccharide components, molecular structure characteristics and antioxidant activities of its derivatives were studied. Then, a series of meaningful data information for the study of the J. regia shell polysaccharide and its derivatives were obtained. The molecular weight of the polysaccharide was 9.45 × 10 4 Da after the separation and purification by DEAE-52 and Sephadex G-100. The polysaccharides contained rhamnose, arabinose, galactose, glucose, xylose and galacturonic acid, and the molar ratio of each monosaccharide component was 6.7%: 16.5%: 28.3%: 11.2%: 12.5%: 24.8%. The molecular structure of J. regia shell polysaccharide contains β-glucoside bond, its structure may be → 4)- α -D-Gal p -(1 → 4)- β -D-GalAp-(1 → 4)- α -D-Xyl p -(1 → glycosidic bond). The study of antioxidant activity, J. regia shell polysaccharide and its derivatives showed good biological activities, especially the phosphorylated J. regia shell polysaccharide. The study of J. regia shell polysaccharide has important practical significance for improving the quality and efficiency of the J. regia industry chain. Graphical Abstract
研究领域:
食品科学
·
植物化学
·
营养学
✓ 已验证
DOI
高影响因子
CATALYSIS LETTERS
·
2018
·Vol. 148
·期 9
·2765-2776
·
IF 2.911
Chang Libin,Zhu Gangqiang,Lu Huan,Hojamberdiev Mirabbos,Zhang Zengping,Gao Jianzhi,Wang Chenghui,Yang Woochul
Abstract The Ag 2 S/CdS composite photocatalyst with a leaf-like structure was synthesized by loading the Ag 2 S nanoparticles on the surface of the hydrothermally synthesized CdS particles. The UV–Vis–NIR absorption spectroscopy results reveal that the Ag 2 S/CdS composite photocatalyst exhibits a wide-spectrum response from ultraviolet (UV) to near-infrared (NIR), demonstrating its potential for effective utilization of solar energy. The scanning and transmission electron microscopic observations show that Ag 2 S nanoparticles with the size of about 20 nm are successfully embedded on the surface of leaf-like structure of CdS. Among the samples loaded with different molar percentages of Ag 2 S nanoparticles, the 5%-Ag 2 S/CdS composite photocatalyst exhibits a higher photocatalytic efficiency than the individually synthesized CdS and Ag 2 S for the degradation of Rhodamine B (RhB) and methyl orange (MO) under LED visible light irradiation. Furthermore, the 5%-Ag 2 S/CdS composite photocatalyst also exhibits a photocatalytic activity for the degradation of RhB under 850 and 940 nm monochromatic light irradiation. The results of the photocatalytic activity tests performed with various scavengers confirm that ·O 2 − plays a key role in the photodegradation of RhB. An enhanced photocatalytic performance of the Ag 2 S/CdS composite photocatalyst is directly attributed to the formation of a heterojunction between Ag 2 S and CdS. The developed composite photocatalyst can harness a greater share of the solar spectrum from visible to near infrared region and generate the photoinduced charge carriers more efficiently. Graphical Abstract
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2021
·Vol. 329
·期 2
·1125-1133
·
IF 1.371
Wu Fan,Zhang Zhibin,Cheng Zhongping,Zhou Runze,Lin Yuling,Liu Yuhui,Wang Youqun,Cao Xiaohong,Liu Mingguang,Liu Yunhai
The photocatalytic reduction of soluble \({\text{UO}}_{2}^{2 + }\) from radioactive wastewater is becoming an effective method to reduce radioactive pollution, while available catalysts are considerable limitation. Herein, the ZnS@g-C 3 N 4 (ZSGCN) heterojunctions complexes were compounded as catalysts to reduce \({\text{UO}}_{2}^{2 + }\) . The results from TEM, XRD, XPS, EIS, DRS and PL showed that the ZnS nanoparticles combined with graphite carbon nitride (GCN), which is the construction of heterojunctions broadened the absorption range of sunlight. The ZSGCN-5 presented the optimal photocatalytic reduction activity to \({\text{UO}}_{2}^{2 + }\) , which was 4.34 times than that of pristine GCN. The ZSGCN-5 heterojunction becomes a promising photocatalyst for radioactive environment remediation.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2019
·Vol. 23
·期 12
·3383-3389
·
IF 2.531
Potapenko Anna V.,Wu Mengqiang,Kirillov Sviatoslav A.
Lithium-manganese-rich–lithiated nickel-manganese-cobalt oxides are advantageous for using in lithium-ion batteries due to low toxicity and high specific capacity but suffer from low high-rate capability. In this paper, characterization and electrochemical testing of 0.5Li 2 MnO 3 ·0.5LiNi 0.5 Mn 0.3 Co 0.2 O 2 (Li 1.2 Ni 0.2 Mn 0.52 Co 0.08 O 2 ) obtained by means of a citric acid–aided route is described. It demonstrates excellent electrochemical performance possessing specific capacity equal to the theoretical value (280 mAh g −1 ), being able to be discharged with currents of 2240 mA g −1 (8 C), having high coulombic efficiency (~ 99%) even after high-rate tests, and manifesting low capacity fade after high current loads and upon further cycling by 0.1 C currents (0.144 mAh g −1 per cycle).
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
Chemistry of Heterocyclic Compounds
·
2020
·Vol. 56
·期 2
·219-225
·
IF 1.519
Li Shengling,Cao Duanlin,Hu Zhiyong,Li Zhichun,Meng Xianjiao,Han Xinghua,Ma Wenbing
In this study, three carbazole-coumarin hybrid dyes were successfully synthesized, and their UV-vis absorption spectra, fluorescence spectra, and structural properties were investigated. The results indicated that diethyl 12-hexyl-2,9-dioxo-9,12-dihydro-2 H -dipyrano[2,3- b :3',2'- h ]-carbazole-3,8-dicarboxylate showed a slight red shift of the maximum absorption wavelength, and its fluorescence intensity was above 4000 arb units, about 22 times higher than that of ethyl 10-hexyl-8-hydroxy-2-oxo-2,10-dihydropyrano[2,3- b ]carbazole-3-carboxylate and ethyl 10-hexyl-8-(hexyloxy)-2-oxo-2,10-dihydropyrano[2,3- b ]carbazole-3-carboxylate in CHCl 3 . The fluorescence intensity of the three compounds first increases and then decreases with the rise of concentration, and the maximum emission wavelength shows a slight red shift. The stability pH range of diethyl 12-hexyl-2,9-dioxo-9,12-dihydro-2 H -dipyrano[2,3- b :3',2'- h ]carbazole-3,8-dicarboxylate in THF was 2–10.
研究领域:
有机化学
·
光化学
·
材料科学
✓ 已验证
DOI
高影响因子
Nano Research
·
2022
·Vol. 16
·期 4
·4634-4642
·
IF 10.269
Zhou Xinyan,Song Kexin,Feng Yu,Jiang Chao,Chen Zhongjun,Wang Zizhun,Yue Nailin,Ge Xin,Zhang Wei,Zheng Weitao
It is challenging for precise governing of electronic configuration of the individually-atomic catalysts toward optimal electrocatalysis, as d-band configuration of a metal center determines the adsorption behavior of reactive species to the center in oxygen reduction reaction (ORR). The addition of Cu atom modifies the d-band center position of Fe central atom, thus strengthening the d—π* orbital interactions. Herein, FeCu-NC catalyst in the nitrogen-doped carbon (NC) support containing individual dual-metal CuN 4 /FeN 4 sites was prepared by the surface confinement strategy of zeolitic imidazolate framework (ZIF), treated as a model catalyst. Experimentally and theoretically co-verified dual-metal CuN 4 /FeN 4 sites highly dispersed in the NC support, enable transferring more electrons from FeN 4 sites to *OH intermediates, thereby accelerating the desorption process of *OH species. Superior to those commercial Pt/C, Our FeCu-NC catalyst exhibited extraordinary ORR activity (with a E 1/2 as high as 0.87 V) and cycling stability in 0.1 M KOH electrolyte, and thereof demonstrated excellent discharge performance in zinc-air batteries. Our construction of dual-atom catalysts (DACs) provides a strategy for atom-by-atom designing high-efficiency catalysts via orbital regulation.
研究领域:
材料科学
·
电化学
·
催化科学
✓ 已验证
DOI
高影响因子
Frontiers in Energy
·
2021
·Vol. 16
·期 6
·931-942
·
IF 2.709
Sun Jing,Yu Guanqun,An Kui,Wang Wenlong,Wang Biao,Jiang Zhenyu,Sun Chenggong,Mao Yanpeng,Zhao Xiqiang,Song Zhanlong
Diverse interactions between microwaves and irradiated media provide a solid foundation for identifying novel organization pathways for energy flow. In this study, a high-energy-site phenomenon and targeted-energy transition mechanism were identified in a particular microwave heating (MH) process. Intense discharges were observed when microwaves were imposed on irregularly sized SiC particles, producing tremendous heat that was 8-fold the amount generated in the discharge-free case. Energy efficiency was thereby greatly improved in the electricity-microwaves-effective heat transition. Meanwhile, the dispersed microwave field energy concentrated in small sites, where local temperatures could reach 2000°C–4000°C, with the energy density reaching up to 4.0 × 10 5 W/kg. This can be called a high-energy site phenomenon which could induce further processes or reactions enhancement by coupling effects of heat, light, and plasma. The whole process, including microwave energy concentration and intense site-energy release, shapes a targeted-energy transition mechanism that can be optimized in a controlled manner through morphology design. In particular, the discharge intensity, frequency, and high-energy sites were strengthened through the fabrication of sharp nano/microstructures, conferring twice the energy efficiency of untreated metal wires. The microwave-induced high-energy sites and targeted energy transition provide an important pathway for high-efficiency energy deployment and may lead to promising applications.
研究领域:
能源科学
·
材料科学
·
物理学
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 27
·13097-13108
·
IF 4.682
Feng Peiyuan,Wang Xiwen,Yang Jin
Cellulose-based aerogels have become a great potential for oil absorption applications due to their wide range of sources, low density, and good adsorption properties. However, many reported cellulose-based aerogels to have the drawbacks of low oil recovery rate and poor mechanical, which limit their application. In this study, high reusable and excellent mechanical properties silylated TEMPO-oxidized nanofibers/polyvinyl alcohol aerogels (STPA) were fabricated through a three-step process of aqueous silylation, bidirectional freezing, and freeze-drying. A bidirectional freezing technique was employed to obtain two unique structural aerogels by adjusting the methyltrimethoxysilane concentration. The STPA possessed many excellent physical properties, such as ultralight (9.79 mg/cm3), hydrophobicity (136°), and compressibility; as an adsorbent, STPA showed high adsorption capacity (51–111 g/g) for various types of organic solvents. Furthermore, the excellent compressibility enables STPA fast and highly efficient recovery of the absorbed oil by simple mechanical squeeze. It possesses an excellent oil recovery rate of 80% and maintains around 90% of its initial saturated absorption capacity after 50 cycles of absorption–squeezing. Therefore, the successful microstructure design of the biomass-aerogel through bidirectional freezing could provide new thoughts for the design of multifunctional oil absorbents and STPA with good mechanical properties and reusability showing promising prospects in the field of water treatment. Graphical abstract
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
JOURNAL OF SURFACTANTS AND DETERGENTS
·
2009
·Vol. 13
·期 2
·155-158
·
IF 0.886
Zhang Jiaoxia,Zheng Yaping,Yu Peiying,He Lin,Wang Huining,Wang Rumin
A trimeric quaternary ammonium salt surfactant containing polyoxyethylene chains was synthesized from fatty alcohol polyoxyethylene ether, pentamethyldiethylenetriamine and thionyl chloride by a two-step process. Its chemical structure was characterized, and the surface activity in aqueous solution was studied at different temperatures. The results showed that when the concentration attains the CMC (1.0 mmol/L), the surface tension is 38.9 mN m −1 and the conductivity is 105.3μS cm −1 at 25 °C. These show that the trimeric quaternary ammonium salt surfactant containing polyoxyethylene chains exhibits high surface activity and effectively reduces the surface tension of water.
研究领域:
化学
·
材料科学
·
表面科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）