ANALYST
·
2014
·Vol. 139
·期 19
·4934-4939
·
IF 3.906
Zhenyu Zhou,Linru Xu,Suozhu Wu,Bin Su
Electrochemiluminescence (ECL) imaging provides a superior approach to achieve array detection because of its ability for ultrasensitive multiplex analysis. In this paper, we reported a novel ECL imaging biosensor array modified with an enzyme/carbon nanotubes/chitosan composite film for the determination of glucose, choline and lactate. The biosensor array was constructed by integrating a patterned indium tin oxide (ITO) glass plate with six perforated poly(dimethylsiloxane) (PDMS) covers. ECL is generated by the electrochemical reaction between luminol and hydrogen peroxide that is produced by the enzyme catalysed oxidation of different substrates with molecular oxygen, and ECL images were captured by a charge-coupled device (CCD) camera. The separated electrochemical micro-cells enabled simultaneous assay of six samples at different concentrations. From the established calibration curves, the detection limits were 14 μM for glucose, 40 μM for lactate and 97 μM for choline, respectively. Moreover, multicomponent assays and cross reactivity were also studied, both of which were satisfied for the analysis. This biosensing platform based on ECL imaging shows many distinct advantages, including miniaturization, low cost, and multi-functionalization. We believe that this novel ECL imaging biosensor platform will have potential applications in clinical diagnostics, medicine and food inspection.
研究领域:
分析化学
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生物传感器
·
电化学
·
医学诊断
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PubMed
高影响因子
INTERNATIONAL COMMUNICATIONS IN HEAT AND MASS TRANSFER
·
2024
·
IF 6.4
Junhui Fan,Dahai Zhu,Yifan Li,Changqing Liu,Huaqing Xie,Wei Yu
Thermal interface materials (TIMs) play a crucial role in addressing the heat dissipation challenges associated with high-power electrical equipment. Apart from possessing excellent thermal conductivity, and they must also exhibit low contact thermal resistance to facilitate efficient heat transfer at the interface. In this study, a novel composite with a dual-network structure was prepared by interfacial grafting to achieve superior thermal conductivity. The composite comprises polydimethylsiloxane (PDMS), functionalized boron nitride ( f -BN), and liquid metal (LM). This dual network structure effectively enhances phonon transportation and significantly improves the thermal transport performance of the composite. The thermal conductivity of the obtained composite can achieve 4.4 W/m·K, accompanied by a low contact thermal resistance of 0.32 °C·cm 2 /W. Furthermore, the dual network structure ensures the flexibility of the composite, as evidenced by the maximum elongation reaching 267.43% at a tensile strength of 0.35 MPa. This exceptional mechanical performance is expected to alleviate stress concentration issues arising from thermal expansion mismatch, thereby enhancing the practical applicability of the prepared TIMs. Overall, this study introduces a novel approach for fabricating flexible composites with high thermal conductivity and low contact thermal resistance, offering new insights into the preparation of TIMs.
研究领域:
材料科学
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热管理技术
·
柔性电子
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DOI
高影响因子
Membranes
·
2025
·Vol. 15
·期 10
·316
·
IF 3.6
Yuan Zhai,Zimeng Zheng,Xinhao Cui,Kun Jiang,Ao Sheng,Heyun Wang
In this study, hydrophilic covalent organic framework (COF) nanosheets with triazine structures and hydrophobic COF nanosheets with fluorinated imine skeletons were designed to enhance the membrane separation process for ethanol pervaporation. The mass transfer of ethanol–water mixtures within the confined structures of COF nanosheets was investigated through experimental characterization and computational simulations, establishing a quantitative relationship between mass transfer performance and the pore size/chemical properties of COF nanosheets. These COF nanosheets were employed to optimize the confined architecture of mixed matrix membranes (MMMs), effectively regulating the critical parameters of MMMs and improving their separation performance. Through systematic investigation of formation mechanisms and modulation principles, we revealed the correlation between confined structural parameters and membrane separation efficiency. This work develops methodologies and foundational theories to overcome the permeability-selectivity trade-off effect, providing theoretical guidance for designing novel membrane materials with ethanol-permelective COF-based MMMs.
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PubMed
高影响因子
PROGRESS IN ORGANIC COATINGS
·
2025
·
IF 7.3
Mengnan Li,Jiawen Sun,Xiaofan Zhai,Jing Yang,Hongmei Ding,Jianrong Song,Sujuan Ye,Jizhou Duan
Marine biofouling presents a significant global challenge today. Silicone-based coatings have garnered considerable interest due to their low surface energy characteristics. However, their practical applications are limited by poor mechanical properties, weak adhesion, and poor static antifouling performance. In response to these inherent limitations, this study innovatively proposed a novel strategy of synergistic nano enzyme-catalyzed sterilization and low surface energy antifouling. A nanocomposite coating, PDMS-PUA-F-Cu, was developed by incorporating peroxidase-like copper nanoparticles (Cu NPs) into a silicone-based polyurethane (PDMS-PUA). The PDMS-PUA was first synthesized through a two-step process using isophorone diisocyanate (IPDI), hydroxy-terminated polydimethylsiloxane (HO-PDMS-OH), and 4,4′-methylenebis(3-chloro-2,6-diethylaniline) (MCDEA) as raw materials. Subsequently, Cu NPs modified with IPDI and polyethylene glycol (PEG) were incorporated into PDMS-PUA to obtain the PDMS-PUA-F-Cu. The resulting coating exhibited enhanced hardness (∼21 MPa) and strong substrate adhesion (∼1.75 MPa) while retaining hydrophobicity and low surface energy. More importantly, the peroxidase-like activity of Cu NPs catalyzed the generation of reactive oxygen species (·OH and ·O 2 − ), enabling dynamic sterilization that significantly enhances the antifouling performance. Experimental results demonstrated outstanding antibacterial rates of ∼98.6 % against Pseudomonas aeruginosa and ∼98.8 % against Staphylococcus aureus , along with remarkable inhibition of Chlorella. adhesion (∼97.4 %). Mechanistic studies confirmed that the synergy between nano enzyme-driven biocidal activity and low surface energy effectively overcame the static antifouling limitations of traditional silicone coatings. This work provides a viable approach for developing high-performance antifouling coatings by combining catalytic sterilization with low-surface-energy coatings.
研究领域:
材料科学
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海洋生物学
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生物医学工程
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DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2022
·
IF 4.831
Zhengdong Zhu,Xiaoyi Shi,Yating Feng,Meng He,Cheng Ye,Hongyang Zhou,Maofeng Zhang,Wei Zhang,Jianhua Li,Changlong Jiang
Conventional surface-enhanced Raman scattering (SERS) molecular detection are based on hard and brittle substrate, which are not suitable for in-situ detection of analytes adsorbed on nonplanar surfaces. Here, we report a simple biomimetic synthesis method to fabricate lotus leaf mastoid structured AgNPs micro/nanoarrays as reliable SERS substrate. By ideal replicating mastoid structure of lotus leaf into a flexible and transparent PDMS film, followed by depositing plasmonic AgNPs, a powerful chemical sensor with high sensitivity and multiplex detecting capability is demonstrated. The employ of periodic mastoid structure array endows the sensor with high signal repeatability (RSD ∼ 8.6 %), solving the general repeatability problem of SERS substrates. In addition, the detailed designed flexible and transparent PDMS substrate is capable of identifying trace analytes on curved surfaces with excellent durability. In the proof-of-concept experiment, a limit of detection (LOD) of (10 −5 M to 10 −7 M) was achieved on a portable Raman device for three common pesticides residues (thiram, fonofos and triadophos) on dendrobium leaves and stem according to the molecular fingerprint, indicating its excellent in-situ detection capability. Further, the multiplex detection ability of the Ag/PDMS film is also demonstrated by analyzing the mixture of four typical analytes. Benefiting from its high signal uniformity, this flexible Ag/PDMS substrate also showed good quantitative detection capabilities.
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PubMed
高影响因子
Analytical Methods
·
2023
·Vol. 15
·期 35
·4582-4590
·
IF 3.1
Xiurui Ke,Jinran Chen,Lin Chang,Zhou Zhou,Wei Zhang
p-Nitrophenol (PNP) is widely used in pesticides, pharmaceuticals, and dyestuffs. It is vital to detect trace PNP in the environment, because it poses significant environmental hazards due to its high toxicity. In this paper, a new method was reported for preparing a SERS substrate with excellent SERS activity by combining self-assembly techniques and flexible materials. First, the three-dimensional (3D) polystyrene (PS) photonic crystal (PC) structural master was fabricated by stacking two layers of self-assembled PS nanospheres with different diameters. Polydimethylsiloxane (PDMS) with a complementary structure to the master was obtained by casting, curing and peeling off. Finally, the PDMS–Ag substrate was fabricated by sputtering a thin Ag layer on the PDMS structure. The enhancement factor (EF) of the PDMS–Ag substrate was calculated to be 2.90 × 109 by using 4-amino thiophenol (ATP) as the probe molecule, and the limit of detection (LOD) for ATP can reach 10−11 M. And the RSD of the SERS intensity for the peak at 1078 cm−1 on the PDMS–Ag substrates from batch to batch was within 2%, indicating the high reproducibility of the as-prepared substrate. The quantitative analysis of PNP was achieved with a LOD of 10−8 M. Therefore, the PDMS–Ag substrate exhibits high sensitivity and reproducibility, and it can detect PNP in trace amounts, with great potential for detecting other contaminants.
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PubMed
高影响因子
LANGMUIR
·
2019
·
IF 3.683
Dong Zhang,Yuzheng Xia,Xiaonong Chen,Shuxian Shi,Lei Lei
Advanced liquid-repelling materials that resist both water-based and oil-based contaminants have significant applications in many fields. Herein, a novel protocol for the fabrication of a robust poly(high internal phase emulsion) (polyHIPE)-based slippery liquid-infused porous surface (SLIPS) system with combined self-repairing and self-cleaning properties is developed. Specifically, polystyrene-based polyHIPE (PS-HIPE) membranes with an interconnected porous structure were prepared from polymerization of the continuous oil phase in the water-in-oil HIPE templates. These polyHIPE membranes were used, for the first time, as porous substrates for loading low surface tension silicone oils as lubricating liquids for the fabrication of polyHIPE-based SLIPS membranes. These polyHIPE-based SLIPS membranes could easily repel both water- and oil-based contaminants (e.g., ink, milk, and coffee) with very low sliding angles (3.0 ? 1.3?) and could even repel solid contaminants (e.g., dust) upon washing with water. Meanwhile, such membranes exhibit excellent self-repairing properties so that physical scratching damage, such as cutting a trench, does not affect the liquid-repelling performance. The liquid-repelling ability could be recovered completely within 10 s. More significantly, such a SLIPS membrane shows excellent durability so that the water sliding angle of the SLIPS could be maintained at less than 5.0? for about 80 cycles owing to the regenerated poly(dimethylsiloxane) layer on the surface. This work represents a robust methodology to enrich the development of hydrophobic and oleophobic slippery surfaces, which is promising for many areas, such as biomedical, self-cleaning, antifouling, and self-repairing materials.
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DOI
PubMed
高影响因子
JOURNAL OF POLYMER RESEARCH
·
2016
·Vol. 23
·期 12
·1-8
·
IF 1.969
Kong Zhineng,Wu Wenting,Yan Jing,Wu Baoying,Zhou Yan,Du Wenqi,Qi Zhengjian
Amphiphilic triblock copolymers containing PDMS and PEG segments were synthesized here by metal-free click chemistry. The structures of PEG-b-PDMS-b-PEG copolymers were characterized through FT-IR, 1 H NMR and GPC. The synthesis procedures of copolymers were carried out under benign conditions without any metal participation. And the self-assembly properties were discussed by fluorescent probe, DLS and TEM result in a lower critical aggregation concentration (CAC), nanoparticles size ranging from 127 nm to 172 nm and formulation of vesicle-like nanoparticles, respectively. Additionally, TGA shows that copolymers exhibits good thermal stability.
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2020
·Vol. 138
·期 19
·50392
·
IF 2.52
Xing Cao,Xiangli Liu,Yan Liu,Rui Ma,Shichang Sun
Numerous cells grow in columnar tissues and organs with different curvatures and curvature gradients. Therefore, it is necessary to study the effect of curvature on cell behavior to control and promote cell development. Herein, we prepared polydimethylsiloxane (PDMS) with different micro-nano patterns using ultraviolet soft lithography. Hydrophilic polydopamine (PDA) was modified on the PDMS surface to prepare PDMS/PDA to improve its biocompatibility. The PDMS/PDA was characterized by contact angle tester and scanning electron microscopy (SEM). The effect of curvature on bone cell migration and differentiation was studied through SEM, inverted phase contrast microscope and fluorescence microscopy. We found that different curvatures had different effects on the bone cell migration and differentiation. Chondrocytes migrated rapidly in grooves with a curvature range of 1/575–1/875 μm −1 . Bone mesenchymal stem cells (BMSCs) had high efficiency of differentiation into chondrocytes in the grooves with a curvature range of 1/775–1/1375 μm −1 . Furthermore, BMSCs showed high efficiency of differentiation into chondrocytes at the edges of micro-nano patterns with different perimeter curvatures, and the differentiation efficiency was the highest at 120° convex curvature. This work shows that curvature is a principle to be considered in bone tissue regeneration engineering and provides inspiration for future biomaterials design.
研究领域:
生物医学工程
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细胞生物学
·
组织工程
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DOI
高影响因子
ACS Photonics
·
2025
·
IF 6.7
Zijun Yan,Yuhui Wang,Shibiao Liu,Wenan Guo,Guolong Chen,Xiaotong Fan,Yue Lin,Shuli Wang,Hao-Chung Kuo,Zhong Chen,Tingzhu Wu
Quantum dot (QD) color conversion layers (CCLs) present an economical and reliable approach to achieve full-color micro-LED displays. Microfluidic technology demonstrates significant advantages for patterning and integrating multicolor QDs, including high precision, rapid processing, low material consumption, and low fabrication costs. However, preparing high-resolution CCLs with low optical crosstalk remains challenging due to limitations in microfluidic chip design induced by swelling of polydimethylsiloxane (PDMS) microchannels in nonpolar solvents utilized for QD dispersion. In this study, we developed a QD solution with a polymer additive that effectively suppresses PDMS swelling, making injection of QD solution into small-sized PDMS microchannels on chromium-patterned microhole glass substrates possible. The resulting QD CCLs exhibit high luminescence uniformity and a high resolution of 1285 ppi, with a subpixel dimension of 5 μm × 5 μm, which is the smallest dimension reported for CCLs fabricated by microfluidic technology. Furthermore, our innovative integration of chromium-patterned microhole glass substrates within a microfluidic device provides unprecedented optical isolation, effectively eliminating intersubpixel crosstalk in CCLs. By integrating optimized red and green QD CCLs with a blue GaN micro-LED array, we successfully fabricated a full-color micro-LED prototype with a resolution of 600 ppi and a wide color gamut of 115% NTSC. Owing to their high resolution, uniform luminescence, and low optical crosstalk, the proposed microfluidic technology holds significant promise for advancing next-generation full-color micro-LED displays.
研究领域:
材料科学
·
纳米技术
·
显示技术
·
微流控技术
·
光电子学
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DOI
高影响因子
Processes
·
2025
·Vol. 13
·期 9
·2757
·
IF 2.8
Xiaozhong Shen,Weibin Yu,Zihao Zhang,Lu Lu,Weiqi Zhang,Huiyuan Liu,Huaneng Su,Lei Xing,Qian Xu
This study employs hydrophobic modification of the current collector to optimize cathode water management and enhance the performance of passive DMFCs. The surface of the cathode current collector was hydrophobized by polytetrafluoroethylene (PTFE) coating and titanium dioxide/polydimethylsiloxane (PDMS) composite coating. The experimental results showed that the surface hydrophobic treatment significantly improved the cell performance at low methanol concentration and marginally improved the cell performance at high methanol concentration. Among them, the DMFC with bilayer TiO2/PDMS hydrophobic-treated cathode current collector with a contact angle of 153.2° showed the best performance, which achieved superhydrophobicity and led to a peak power density that was 27.25% higher compared to the DMFC with an untreated current collector. With the gradient-based hydrophobic treatment for the cathode current collector, the best performance was achieved when double-layer TiO2/PDMS was used on the MEA side and PTFE coating on the air side.
研究领域:
能源工程
·
燃料电池技术
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表面化学
·
材料科学
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DOI
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Lili Li,Yingdan Song,Hongxin Song,Kaige Cheng,Qiang Xu,Lei Zhao
The light waveguiding effect of transparent glass ceramics (GCs) on mechanoluminescence (ML) signals is highly attractive for remote stress sensing and structural health monitoring applications. However, a prerequisite for generating ML in GCs is pre-irradiation with high-energy rays, which not only increases application costs but also poses a risk of GCs devitrification. Herein, we propose a safe, non-destructive, and convenient charging method for the ML of KMgF 3 : Tb 3+ GCs, namely ultraviolet (UV) light charging. By effectively filling the intrinsic defects in KMgF 3 : Tb 3+ nanocrystal using UV light, we achieved trap-controlled ML in rigid GCs. Moreover, this ML is attributed to thermoluminescence (TL) induced by frictional heating during mechanical stimulation. Additionally, when the GCs powder is combined with flexible polydimethylsiloxane (PDMS), a self-powered (without any pre-charging) ML induced by interfacial triboelectricity can also be achieved, which is similar to the results observed in most flexible ML systems. This work proposes a more straightforward and safer approach for applications such as mechanical sensing based on the ML of transparent GCs.
研究领域:
材料科学
·
光学
·
传感技术
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DOI
高影响因子
危险品化学品经营许可证（带存储）