Theranostics
·
2022
·
IF 11.6
Qiqi Xu,Yuetong Zhang,Zulu Yang,Guohui Jiang,Mingzhu Lv,Huan Wang,Chenghui Liu,Jiani Xie,Chengyan Wang,Kun Guo,Zhanjun Gu,Yuan Yong
Nanozyme-based tumor collaborative catalytic therapy has attracted a great deal of attention in recent years. However, their cooperative outcome remains a great challenge due to the unique characteristics of tumor microenvironment (TME), such as insufficient endogenous hydrogen peroxide (H 2 O 2 ) level, hypoxia, and overexpressed intracellular glutathione (GSH). Methods: Herein, a TME-activated atomic-level engineered PtN 4 C single-atom nanozyme (PtN 4 C-SAzyme) is fabricated to induce the “butterfly effect” of reactive oxygen species (ROS) through facilitating intracellular H 2 O 2 cycle accumulation and GSH deprivation as well as X-ray deposition for ROS-involving CDT and O 2 -dependent chemoradiotherapy. Results: In the paradigm, the SAzyme could boost substantial ∙OH generation by their admirable peroxidase-like activity as well as X-ray deposition capacity. Simultaneously, O 2 self-sufficiency, GSH elimination and elevated Pt 2+ release can be achieved through the self-cyclic valence alteration of Pt (IV) and Pt (II) for alleviating tumor hypoxia, overwhelming the anti-oxidation defense effect and overcoming drug-resistance. More importantly, the PtN 4 C-SAzyme could also convert O 2 ·- into H 2 O 2 by their superior superoxide dismutase-like activity and achieve the sustainable replenishment of endogenous H 2 O 2 , and H 2 O 2 can further react with the PtN 4 C-SAzyme for realizing the cyclic accumulation of ∙OH and O 2 at tumor site, thereby generating a “key” to unlock the multi enzymes-like properties of SAzymes for tumor-specific self-reinforcing CDT and chemoradiotherapy. Conclusions: This work not only provides a promising TME-activated SAzyme-based paradigm with H 2 O 2 self-supplement and O 2 -evolving capacity for intensive CDT and chemoradiotherapy but also opens new horizons for the construction and tumor catalytic therapy of other SAzymes.
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高影响因子
CORROSION SCIENCE
·
2020
·
IF 6.479
Junying Hu,Qi Xiong,Longjun Chen,Chenfeng Zhang,Ziqi Zheng,Shuai Geng,Zhi Yang,Xiankang Zhong
The corrosion inhibition of carbon steel in CO 2 -O 2 -containing environment is one of the biggest challenges in flue gas injection for enhanced oil recovery. Herein we report the possibility to use Bis(2-ehylhexyl) phosphate (BEP) to inhibit the corrosion in CO 2 -O 2 -containing solution and simultaneously the inhibition mechanisms are unmasked. The results show that the corrosion is greatly inhibited with 500 ppm BEP in 1 wt% NaCl solution with 0.02 MPa CO 2 and 3 mg/L O 2 . BEP could interact with Fe and corrosion products via the formation of P-O-Fe bond and P-Fe bond to generate a barrier layer, thus, offering a protective performance.
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BIOCONJUGATE CHEMISTRY
·
2021
·
IF 4.774
Chunxiao Sui,Rui Tan,Yiwen Chen,Guotao Yin,Ziyang Wang,Wengui Xu,Xiaofeng Li
Metal–organic frameworks (MOFs) derivatives had been widely explored in electronic and environmental fields, but rarely evaluated in the biomedical applications. Herein, Fe–N codoped carbon (FeNC) nanoparticles were synthesized and characterized via facile pyrolysis of precursor ZIF-8 (Fe/Zn) nanoparticles, and their potential applications in tumor therapy were assessed in this investigation both in vitro and in vivo. After PAA (sodium polyacrylate) modification, the FeNC@PAA nanoparticles were able to initiate a Fe-based Fenton-like reaction to generate ·OH and O2 for chemodynamic therapy (CDT) and O2 evolution. Meanwhile, the porphyrin-like metal center in the FeNC@PAA nanoparticles could be used as a photosensitizer for photodynamic therapy (PDT) of tumors, which could be enhanced by O2 generated in CDT. Furthermore, the FeNC@PAA nanoparticles were also found to be effective in photothermal therapy (PTT) with a photothermal conversion efficiency of 29.15%, owing to a high absorbance in the near-infrared region (NIR). In conclusion, the synthesized FeNC@PAA nanoparticles exhibited promising applications in O2 evolution and CDT/PDT/PTT synergistic treatment of tumors.
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高影响因子
JOURNAL OF POWER SOURCES
·
2020
·
IF 8.247
Ying Wang,Dan Li,Siqi Zhang,Ziye Kang,Haiming Xie,Jia Liu
Although dual redox mediators (RMs) largely promote the discharge capacity and decreases the charge overpotential in Li-O 2 batteries , the shuttle effect leads to a RM degradation and a serious deterioration of Li metal, which results in a poor sustainability. Here, a poly (3,4-ethylenedioxythiophene):poly (styrenesulfonate) (PEDOT:PSS) -decorated separator has been firstly introduced into a dual mixture RMs-involved Li-O 2 system, which restrains the shuttle effect via coulombic interactions. Benefiting from the advantages of as-prepared separator, a cell exhibits an enhanced cycling stability and a good reversibility associated with the Li 2 O 2 formation and decomposition during cell cycling. These results represent a promising progress in the development of an easy-to-operate modified separator for a highly efficient Li-O 2 battery.
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高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2018
·
IF 4.61
Sharafat Ali,Izaz Ali Shah,Aziz Ahmad,Javed Nawab,Haiou Huang
In this study, pristine multi-walled carbon nanotubes (MWCNTs) were functionalized by using Ar/O 2 plasma treatment technique, which enhanced adsorptive membrane filtration of zinc ions from water and wastewater. The XPS analysis showed that plasma treatment largely increased the surface oxygen groups content of MWCNTs from 2.78% to 6.79%. This change increased the surface negative charged, dispersion and adsorption properties of MWCNTs without causing any damages to the integrity of the nanotube pattern. Pressure-driven filtration of plasma-treated MWCNT (P-CNT) dispersion formed a stable layer inside the lumen of a hollow fiber membrane. The contact angle analysis demonstrated that after incorporation of P-CNT into the HF membrane increased membrane hydrophilicity. The P-CNT membrane effectively removed almost 100% of zinc from synthetic waters and approximately 80% of zinc from a wastewater effluent by surface complexation reaction. A follow-up regeneration study demonstrated that the adsorptive removal of zinc by the CNT membrane was reversible under selected conditions, thus making it possible to repeatedly use the membrane for long-term zinc filtration. This study suggests that HF membranes modified with P-CNTs possess superb adsorption properties for metal ions , allowing the operation of CNT membranes for water treatment .
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高影响因子
Journal of Materials Chemistry A
·
2021
·Vol. 9
·期 8
·4880-4889
·
IF 12.732
Wei Wu,Wang Lin,Hongjiang Chen,Keyan Wei,Zhitong Li,Haitao Yang,Mingxian Liu,Huaicheng Xiang,Libo Deng,Lei Yao
The development of high-performance solid-state batteries (SSBs) that integrate high safety with high energy density has long been pursued. However, conventional lithium-containing anode materials are unable to balance these two requirements, thereby necessitating the exploration of lithium-free anodes for SSBs. In the current study, a core–shell lithium-free α-Fe2O3@TiNb2O7 (TNO) nanofiber composite is synthesized and applied as an SSB anode. The confinement effect from the hollow TNO nanotubes on the encapsulated α-Fe2O3 nanoparticles can buffer the volume-change crushing during charging/discharging, leading to robust structural stability. Moreover, the high rate capability of TNO and high capacity of α-Fe2O3 work synergistically to provide superior electrochemical performances. The prepared α-Fe2O3@TNO composite delivers twice the reversible capacity (625 mA h g−1 at 0.1 A g−1) of pristine TNO as well as a remarkably prolonged cycle life (500 cycles with 79.2% capacity retention) and an improved rate performance (305 mA h g−1 at 3 A g−1) compared with those of α-Fe2O3, making this composite the most efficient TNO-based anode material ever reported. By pairing the composite with the high-energy Li[Ni0.8Co0.1Mn0.1]O2 (NCM811) cathode, the SSB full cell exhibits a high energy density of 400 W h kg−1. These results demonstrate the feasibility and great potential of the proposed lithium-free anode material in SSBs for practical applications.
研究领域:
材料科学
·
电化学
·
能源存储
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高影响因子
Catalysts
·
2025
·Vol. 15
·期 6
·545
·
IF 4
Xiaohong Yao,Jian Zhang,Chao Long
This study explored how pore size engineering in Nb-Mn/MCM-41 catalysts affects plasma-catalytic toluene oxidation. Adjusting the pore diameter (2.49–3.98 nm) modulated metal-support interactions and oxygen dynamics, with pore expansion to 3.73 nm (M3) optimizing the Mn4+/(Mn2++ Mn3+) ratio (XPS: 36.8%), the amount of lattice oxygen species (O2-TPD: 0.222 mmol/g), and crystallite size control (1.5 ± 0.2 nm, TEM). Smaller pores (M1: 2.49 nm) enhanced toluene adsorption but limited active site accessibility, while oversized pores (M4: 3.98 nm) reduced oxygen storage capacity (0.600→0.412 mmol/g). The Nb-Mn/M3 catalyst achieved superior performance with 96.8% toluene conversion, 55.0% CO2selectivity, and 85.4% carbon balance, while minimizing organic byproducts (GC-MS). Mechanistic studies revealed pore-mediated oxygen storage-transport cycles as critical for decoupling adsorption and oxidation steps. This study reveals fundamental mechanisms linking pore architecture to plasma-catalytic synergy in toluene oxidation, offering critical insights for the systematic design of energy-efficient, plasma-catalytic systems targeting industrial VOCs remediation.
研究领域:
催化化学
·
环境化学
·
材料科学
·
等离子体化学
·
纳米技术
·
表面科学
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APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Tong Zhou,Guohui Dong,Jiahao Geng,Kai Han,Chenyang Xiao
In this study, a novel Z-scheme + II-type ternary heterojunction nanocomposite was prepared by one-step solvothermal method using g-C 3 N 4 , FeS 2 and Fe 2 O 3 as raw materials. The successful preparation of this ternary heterojunction was confirmed by the structural analysis and the surface morphology study. Compared with g-C 3 N 4 , the ternary photocatalyst showed excellent photocatalytic performance for the degradation of tetracycline (TC). The enhancement of photocatalytic activity is mainly due to the increase of light absorption capacity, effective separation of carrier in space, and increase of electron transfer channels in this Z-Scheme + II-type composite system. The scavenger test and electron spin resonance spectroscopy show that O 2 − is the main oxidizing free radical in the photocatalytic system. Based on liquid chromatograph-mass spectrometer, a possible degradation pathway of TC was proposed. This study opens up a new idea for the design and synthesis of efficient Z-Scheme + II-type photocatalysts for environmental purification.
研究领域:
环境科学
·
材料科学
·
化学
·
光催化
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高影响因子
ENVIRONMENTAL TECHNOLOGY
·
2015
·
IF 1.56
Qunxing Huang,Xu Cai,Moussa Mallaye Alhadj Mallah,Yong Chi,Jianhua Yan
The high concentration of heavy metals in solid wastes may cause serious pollution during thermal treatment. We have investigated, theoretically and experimentally, the effects of several important flue gas species and mineral sorbents on the partitioning behaviour of four major heavy metals (cadmium, lead, zinc and copper) which are often present in municipal solid waste (MSW). Their concentrations in bottom ash, fly ash and flue gas were quantified when model MSW samples were treated thermally under different conditions. The evaporation ratio of the four metals, excluding Cu, increased with decreasing oxygen concentration. The presence of HCl promotes heavy metal evaporation by preventing the formation of stable metallic species, especially for Zn (evaporation of more than 20%). An increase in oxygen concentration has a negative influence on the effect of HCl. In the presence of SO2, Cd and Pb exhibited a higher evaporation ratio, while Zn and Cu were insensitive to the change. SO2 also inhibits Cd vaporization in an oxidative atmosphere. The effect of NH3 on reducing the metal volatilization rate was established indirectly. Calcium oxide addition enhances metal evaporation except for that of Zn (which shows a decrease of 38%). Although desulphurization by calcium injection decreases the volume of acid gas, calcium affects heavy metal pollution control adversely. The presence or addition of SiO2- or Al2O3-containing minerals can lead to the formation of stable metallic salts. This may favour the control of Cd, Pb, Zn and Cu volatilization up to 13%, 50%, 17.5% and 19%, respectively.
研究领域:
环境科学
·
废物处理
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高影响因子
Molecular Catalysis
·
2020
·
IF 3.687
Hai-Min Shen,Lei Liu,Bei Qi,Meng-Yun Hu,Hong-Liang Ye,Yuan-Bin She
Non-solvent and non-additive oxidation of secondary benzylic C–H bonds to aromatic ketones utilizing simple metalloporphyrins as catalysts and O 2 was investigated systematically. Based on systematical studies on reaction parameters, such as the structures of porphyrins, the types of central metals, the amount of catalyst, the pressure of oxygen, and the temperature, most aromatics with secondary benzylic C–H had been converted efficiently and selectively to their corresponding aromatic ketones catalyzed by the optimized metalloporphyrin catalyst T(2,3,6-triCl)PPCo. And the selectivity towards aromatic ketones reached up to 80 %–95 % with acceptable conversions in lower catalyst-loading (2.4 × 10 −3 %, mol/mol). The highest selectivity was achieved for substrate 1,2,3,4-tetrahydronaphthalene with the selectivity of 95.0 % in the conversion of 46.3 %. The superior catalytic performance of T(2,3,6-triCl)PPCo could be mainly ascribed to its excellent plane structure, superior ability for electron transfer and low positive charge around the central metal. All of above properties promoted the formation of catalytic active species high-valence cobalt-oxo complexes, and facilitated the approach of substrates to the catalytic active centers. This work presented an optimized balance among higher selectivity, milder conditions, lower catalyst-loading, and simpler catalysts compared with current documents, which was not only an efficient, practical and significant strategy to functionalize the widely available aromatics possessing secondary benzylic C H with high efficiency and selectivity under milder conditions, but also an important instance in the effective functionalization and utilization of other C H bonds employing optimized catalytic systems based on metalloporphyrins.
研究领域:
有机化学
·
催化化学
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Yingying Zhang,Qiang Huang,Ruoting Wang,Xinjie Du,Yu Yu,Zhe Chen
Modulating the coordination environment of single-atom catalysts (SACs) and designing architectures to maximize the exposure of active sites are pivotal strategies for enhancing peroxymonosulfate (PMS) activation. The fabrication of single-atom‑iron catalysts on support with particular coordination is essential but still remains challenge. Herein, we proposed the construction of single-atom‑iron embedded in graphitic carbon nitride nanosheets (SA-Fe@C 3 N 4 ) catalyst. The layer-confined synthesis strategy realized the loading of single-atom irons and ultrathin C 3 N 4 nanosheet formation in the interlayer of layered template RUB-15. XANES analysis corroborated that the isolated iron atoms are coordinated with three nitrogen and one oxygen atoms (Fe-N 3 O 1 ). Notably, the single iron atoms within the SA-Fe@C 3 N 4 matrix serve as the predominant active sites for PMS activation. The catalyst exhibited exceptional activity for the degradation of sulfamethoxazole (SMX), achieving a mass-normalized rate constant ( k Fe ) of 1.54 × 10 5 min −1 mol −1 with high selectivity toward 1 O 2 /•O 2 − .Theoretical calculations revealed that the Fe-N 3 O 1 moiety accelerated the PMS adsorption and reduced energy barriers for the activation of PMS, thus produce key *O intermediate SO 5 •- and form 1 O 2 /•O 2 − with nearly 100% selectivity. This study supplied a simple avenue to fabricate single-atom‑iron on C 3 N 4 with regulated coordination for wastewater treatment.
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ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2025
·
IF 11.3
Hao Liu,Siqing Cheng,Jianjun Chen,Xiaoping Chen,Shangchao Xiong,Fang Huang,Houfeng Liu,Junhua Li,Chuanzhi Sun
Mitigating industrial nitrous oxide (N2O) emissions is critical for climate action, yet developing efficient low-temperature N2O decomposition catalysts under O2-containing conditions remains challenging. The weak oxygen–support interaction leads to unsatisfactory N2O decomposition performance in the supported Co3O4/CeO2 catalyst. This study aims to enhance the electronic oxide–support interaction in the Co3O4/CeO2 catalyst through Zn doping, thereby improving its catalytic performance for N2O decomposition under O2-rich conditions. The results demonstrate that, in the presence of 5% O2, the activation energy of the catalyst sharply decreases from 117.5 to 60.4 kJ·mol–1 after Zn doping (Co2.4Zn0.6O4/CeO2). Additionally, the doped catalyst exhibits strong durability to the O2 + H2O + NOx impurity gas components. Advanced spectral characterization and density functional theory calculations reveal that Zn doping modulates the geometry and electronic structure of active cobalt sites, optimizing the adsorption and activation capabilities of N2O molecules. This study elucidates the mechanism of N2O decomposition over the catalysts and establishes a clear structure–activity relationship between the atomic-scale configuration of active sites and their performance. These findings provide critical insights for designing efficient supported oxide catalysts through targeted doping strategies and offer new perspectives for developing highly efficient and low-energy N2O decomposition catalysts.
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