DALTON TRANSACTIONS
·
2024
·
IF 3.5
Na Lin,Yun-Xia Li,Yu Liu,Kai-Qi Sun,Hong-Yan Zhang,Xiao-Wu Lei,Zhi-Wei Chen
Low-dimensional organic–inorganic hybrid lead halide perovskites have attracted much interest in solid-state lighting and displays, but the toxicity and instability of lead halide are obstacles to their industrial applications, which must be overcome. As an alternative, Cu(I)-based hybrid metal halides have emerged as a new type of luminescent material owing to their diversified structure, adjustable luminescence, low toxicity and low cost. Herein, we report three one-dimensional (1D) hybrid Cu(I)-based halides with the general formula ACu2Br4 (A = [(Me)4-Pipz]2+ and [BuDA]2+ and [TMEDA]2+). These 1D hybrid Cu(I) halides display stable broadband blue emission with maximum emission peaks in the range of 445–474 nm and the highest photoluminescence quantum yield of 37.8%. Furthermore, in-depth experimental and theoretical investigations revealed that the broadband blue emissions originate from the radiative recombination of self-trapped excitons. Most importantly, there is no structural degradation and attenuation of emission intensity even after continuously soaking these halides in water for at least two months, demonstrating their ultra-high anti-water stability. Hirshfeld surface analysis shows that a large number of weak hydrogen bonds can protect the inorganic skeleton from degradation due to water. This work provides a new strategy for the design of water-stable Cu(I)-based halides with efficient blue emission and wide potential applications in humid environments.
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高影响因子
ORGANOMETALLICS
·
2012
·
IF 3.963
Mei-Jin Li,Xing Liu,Mei-Juan Nie,Zhao-Zhen Wu,Chang-Qing Yi,Guo-Nan Chen,Vivian Wing-Wah Yam
A series of the luminescent Re(I) complexes, [Re(bpy-(CH2OH)2)(CO)3(L1)], [Re(bpy-(CH2OH)2)(CO)3(L2)]+, [Re(bpy-(CH2OH)2)(CO)3(L3)]+, and [Re(bpy-(CH2OH)2)(CO)3(L4)] ((bpy-(CH2OH)2 = 4,4′-bis(hydroxymethyl)-2,2′-bipyridine; L1 = 4-pyridylmethyl lipoate; L2 = [1,2]dithiolane-3-pentyl 4-pyrindylacetate; L3 = 4-pyridinyl-methanol; L4 = 4-pyridinylmethyl pentanoate), were synthesized and characterized. The photophysical properties and cytotoxicity of the complexes and the sensing of esterase based on the gold nanoparticles (Au-NPs) modified with the complexes were also studied. The intense luminescence of the Re(I) complexes was quenched efficiently by Au-NPs due to the energy and electron transfer between the Re(I) fluorophores and Au-NPs. Upon addition of esterase to the mixture, the emission of the Re(I) complexes 1 and 2 system was enhanced significantly by the release of the Re(I) complexes from the surface of the Au-NPs.
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Marine Drugs
·
2017
·Vol. 15
·期 7
·217
·
IF 3.503
Lan-Ting Xin,Lu Liu,Chang-Lun Shao,Ri-Lei Yu,Fang-Ling Chen,Shi-Jun Yue,Mei Wang,Zhong-Long Guo,Ya-Chu Fan,Hua-Shi Guan,Chang-Yun Wang
Currently, DNA topoisomerase I (Topo I) inhibitors constitute a family of antitumor agents with demonstrated clinical effects on human malignancies. However, the clinical uses of these agents have been greatly limited due to their severe toxic effects. Therefore, it is urgent to find and develop novel low toxic Topo I inhibitors. In recent years, during our ongoing research on natural antitumor products, a collection of low cytotoxic or non-cytotoxic compounds with various structures were identified from marine invertebrates, plants, and their symbiotic microorganisms. In the present study, new Topo I inhibitors were discovered from low cytotoxic and non-cytotoxic natural products by virtual screening with docking simulations in combination with bioassay test. In total, eight potent Topo I inhibitors were found from 138 low cytotoxic or non-cytotoxic compounds from coral-derived fungi and plants. All of these Topo I inhibitors demonstrated activities against Topo I-mediated relaxation of supercoiled DNA at the concentrations of 5–100 µM. Notably, the flavonoids showed higher Topo I inhibitory activities than other compounds. These newly discovered Topo I inhibitors exhibited structurally diverse and could be considered as a good starting point for the development of new antitumor lead compounds.Keywords:virtual screening;molecular docking;Topo I inhibitor;low toxic;natural product
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Cheng Zhang,Kui Zhang,Tingting Zhao,Bianhua Liu,Zhenyang Wang,Zhongping Zhang
Pesticides abuse has drawn considerable attention in agriculture, environment and food safety in recent years. How to selective and on-site detection of pesticide residues with rapid operation and low cost is still a hot topic. In this work, we report a novel method for the detection of pesticide thiram using phosphorescent Mn-doped ZnS quantum dots (ZnS:Mn 2+ QDs) combined by an affinity reaction between thiram and Ag + ions. On the one hand, the phosphorescence of as-prepared ZnS:Mn 2+ QDs at 590 nm can be effectively quenched by Ag + ions due to the direct cation-exchange reaction at the surface of QDs. On the other hand, the presence of thiram can inhibit phosphorescence quenching through the formation of stable Ag-thiram complex. This inhibition resulted in a linear recovery in emission intensity with increasing the amount of thiram, which enables thiram residues to be identified under the UV light illumination. In buffer condition, thiram could be detected within the concentration range of 50 nM–2.5 μM with a detection limit of 25 nM. Moreover, the proposed method has been successfully applied to thiram residues identification at fresh fruit peels. The investigation provides a profile for instant and visual detection of surface residues using doped quantum dots.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2017
·
IF 2.843
Yongli Sun,Hanrong Bi,Haozhen Dou,Huawei Yang,Zhaohe Huang,Baoyu Wang,Rong Deng,Luhong Zhang
For the separation of an ethylene/ethane mixture, a novel copper(I)-based supported ionic liquid membrane (SILM) with high permeability has been fabricated. This SILM was prepared from a polyvinylidene fluoride microporous membrane impregnating the copper(I) based IL which formed by the cuprous chloride (CuCl) and 1-butyl-3-methylimidazolium chloride ([Bmim][Cl]). Scanning electron microscopy, attenuated total reflection Fourier transform infrared spectroscopy, and time of flight mass spectroscopy were used to characterize the SILM. Pure and mixed gas permeation experiments were carried out to investigate the influences of ILs composition, trans-membrane pressure, temperature, and time upon the separation performance. This SILM showed comparable C2H4 permselectivity but outstanding permeability with a long-term stability beyond the reported polymeric membrane upper bound. At the CuCl/[Bmim][Cl] ratio of 2, the C2H4 permeability and permselectivity reached 2653 barrer and 11.8, respectively. Furthermore, the facilitated transport effect was studied by 1H NMR and quantum mechanical calculations. The anionic species formed by sp hybridization of Cu+ possesses unfilled attachment sites to selectively complex with C2H4 and weaken the interionic hydrogen bond of [Bmim][Cl], thus lowering the system’s viscosity.
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高影响因子
CRYSTAL GROWTH & DESIGN
·
2015
·
IF 4.891
Min Xue,Yanchao Lü,Qingqing Sun,Kaiqiang Liu,Zhen Liu,Ping Sun
Three Schiff base ligands containing two pyridine rings, S1, S2, and S3, show strong gelation abilities with AgNO3 in several pure or mixed solvents at room temperature. 1H NMR and Fourier transform infrared spectroscopy measurements not only demonstrated the coordination interaction between silver ion and nitrogen atom of the pyridine ring of the S2 ligand in S2-Ag metallogel, but also showed that hydrogen bonding contributes to the formation of the metallogels. In particular, S2-Ag metallogel shows a super smart and fully reversible thixotropic property, which has been rarely reported before in metallogels. X-ray diffraction (XRD) analysis revealed that S2-Ag metallogel in DMF takes a mixture of hexagonal and tetragonal packing modes. On the basis of the results of XRD and mass spectrometry analysis, a possible structure evolution process for the gel was proposed. And this model was further demonstrated by the results of polarizing microscopy and thermogravimetric analysis of S2-Ag metallogel.
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2017
·
IF 2.714
Yong Cheng,Feifei Sun,Qichun Feng,Qiang Zhao,Yinghua Zhou
In this study, we describe the successful fabrication of silver nanoparticles (AgNPs) within Ag(I)-AMTD metal-organic gel matrix. The resulting composite (AgNPs@Ag(I)-AMTD) was characterized by 1 H NMR, IR, SPR, SEM, TEM, EDX, XPS, and XRD. This material exhibited a remarkable and durable activity for the catalytic reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP) and other nitroarenes by NaBH 4 in aqueous solution. This method affords a facile means of embedding the active silver nanoparticles within the metal-organic gel matrix and offers the necessary stability of the resulting silver nanostructure for catalytic transformation.
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高影响因子
NANO
·
2015
·
IF 1.09
Yu Cao,Zhihui Fang,Duanguang Yang,Yong Gao,Huaming Li
We reported a sensitive voltammetric sensor for Sudan I determination by modifying glassy carbon electrode (GCE) with single-walled carbon nanotubes (SWCNTs)/β-cyclodextrin conjugate. The cyclic voltammetry results showed that the modified GCE exhibited strong catalytic activity toward the electro-reduction of Sudan I with a well-defined cyclic voltammetric peak at -673 mV. Differential pulse voltammetry measurement showed that the response current exhibited a linear range between 50 nM and 5 μM, and the detection limit was as low as 2.22 nM (S/N = 3). The enhanced electrochemical performance of the fabricated sensor was attributed to the combination of the excellent electrocatalytic properties of SWCNTs and the molecular recognition ability of β-cyclodextrin to Sudan I. The sensor was successfully applied to determine Sudan I in real food samples with satisfactory results.
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高影响因子
Analytical Methods
·
2024
·Vol. 16
·期 26
·4402-4408
·
IF 2.7
Yan Tang,Fuzhong Chen,Wei Lv,Zixuan Zhou,Yulin Fu,Yuan Qin,Xueqin Zhao,Junhong Wang,Biao Huang
Myocardial infarction occurs rapidly, and thus the rapid detection of cTnI levels is the key to its diagnosis. Most current assays take 10–30 min. In this study, we developed a method for accurately measuring cardiac troponin I (cTnI) levels in human sera with amplified luminescence neighborhood homogeneous assay (AlphaLISA). The method involves coupling two cTnI antibodies targeting different epitopes to the surface of carboxylated donor and acceptor beads. The final signal values were detected by the double-antibody sandwich method, and the best reaction conditions were obtained by optimizing the experimental conditions. The sensitivity, specificity, accuracy, and precision of the method were evaluated. Results showed that the method requires only 3 min to produce the results, the detection sensitivity is 27.06 ng L−1, and the measurement range is 34.56–62 500 ng L−1. cTnI-AlphaLISA has an intra-assay precision of 2.18–4.57% (<10%) and an inter-assay precision of 5.60–6.95% (<10%). The relative recovery rates are within reasonable limits. In addition, the serum assay results of the method were compared with chemiluminescence immunoassay, and the results are in agreement with one another (ρ = 0.8803; P < 0.0001). The method is expected to be developed as a routine method, but further studies and evaluations are needed.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2024
·
IF 8
Linge Nian,Wenhua Li,Minhui Dai,Chunxia Zhang,Lu Li,Guangrui Zhang,Jianxi Xiao
The precise detection of pathological type I collagen is critical for diagnosing and prognosticating various diseases such as fibrosis and tumors. Surface-enhanced Raman scattering (SERS) is emerging as a promising high-resolution imaging technique, yet the intricate process of covalently modifying antibodies often results in SERS probes with diminished selectivity. We herein for the first time report the development of dual SERS peptide probes, Ag@R1@PCTP (S-P) and Ag@R2@ICTP (S-I), which integrate collagen targeting peptides (CTPs), Raman reporters, and silver nanoparticles (Ag NPs) for specific imaging of pathological type I collagen in connective tissues. The S-P/S-I dual SERS peptide probes displayed distinct peaks at 2154 cm −1 and 2227 cm −1 in the Raman silent region with no overlap, showcasing their capability for multiplex imaging free from cross-interference. The SERS peptide probe S-P is specifically tuned to target pathological collagen, excluding intact collagen, while S-I effectively recognizes type I collagen in both its pathological and healthy states. The S-P/S-I probes have exhibited outstanding effectiveness in identifying pathological type I collagen across various connective tissues and have been successfully applied for imaging this collagen in a variety of cancer tissues. The innovative dual SERS peptide probes offer a highly specific and robust tool for imaging pathological type I collagen in tissues, presenting significant potential for the accurate diagnosis and treatment of a range of collagen-related diseases.
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INORGANIC CHEMISTRY
·
2024
·
IF 4.3
Xing Liu,Ting Zhang,Lei Zhou,Ming Li,Rongxing He
A highly luminescent (C13H28N2)2Cu4I8 single crystal containing isolated γ-[Cu4I8]4– anionic cluster was synthesized without the use of unsaturated cations. To the best of our knowledge, compounds bearing such like anions are not dual-emitting under UV excitation. However, dual emission does occur in (C13H28N2)2Cu4I8. Moreover, the emission bands were found to be temperature-sensitive, allowing tuning of the emission colors from blue (0.19, 0.20) to green (0.33, 0.47) in the Commission International de L’ Eclairage (CIE) chromaticity coordinates. Remarkably, the color could be restored on returning to the initial temperature, confirming an efficient and reversible luminescent thermochromic effect in (C13H28N2)2Cu4I8. The origin of this excellent optical performance is discussed, and the difference in the mechanism with the dual-emissive Cu(I) halide complexes is also elucidated. Overall, our work provides a promising way to achieve efficient luminescent thermochromism. The developed (C13H28N2)2Cu4I8 represents one of the viable alternatives for eco-friendly luminescent thermochromic materials.
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高影响因子
Chemosensors
·
2024
·Vol. 12
·期 10
·214
·
IF 3.7
Yun Hui,Weijun Kong,Weiliang Shu,Zhiting Peng,Fengshan Shen,Mingyang Jiang,Zhen Xu,Tianzhun Wu,Wenhua Zhou,Xue-Feng Yu
The measurement of cardiac troponin I (cTnI) is of vital importance for the early diagnosis of acute myocardial infarction. In this study, an enhanced electrochemiluminescent immunoassay for the highly sensitive and precise determination of cTnI was reported. A biomimetic chip with nepenthes peristome surface microstructures to achieve single-layer microbead arrays and integrated microelectrode arrays (MEAs) for ECL detection was microfabricated. Ru@SiO2nanoparticles were prepared as signal amplificators labeling immunomagnetic beads. Dendrimer-encapsulated platinum nanoparticles (Pt DENs) were electrochemically modified on ITO MEAs. The resulting Pt DEN-modified ITO MEAs preserved good optical transparency and exhibited an approximately 20-fold ECL signal amplification compared to that obtained from bare ITO. The method made full use of the biomimetic chip with Pt DENs to develop single-layer immunomagnetic bead arrays with increasingly catalyzed electrochemical oxidation of the [Ru(bpy)3]2+–TPA system. Consequently, a limit of detection calculated as 0.38 pg/mL (S/N = 3) was obtained with excellent selectivity, demonstrating significant potential for the detection of cTnI in clinical diagnostics.
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