APPLIED SURFACE SCIENCE
·
2014
·
IF 2.538
Yanling Hao,Zhixing Gan,Jiaqing Xu,Xinglong Wu,Paul K. Chu
Although carbon quantum dots (CQDs) possess excellent luminescence properties, it is a challenge to apply water-soluble CQDs to tunable luminescent devices. Herein, quaternary CQDs are incorporated into poly(ethylene glycol) to produce poly(ethylene glycol)/CQD composite solid films which exhibit strong and tunable blue–red emission. The fluorescent quantum yield reaches 12.6% which is comparable to that of many liquid CQDs and the photoluminescence characteristics are determined to elucidate the fluorescence mechanism. The CQD solid films with tunable optical properties bode well for photoelectric devices especially displays.
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DOI
高影响因子
ENERGY & FUELS
·
2019
·
IF 3.021
Shuang Zhu,Jiaolai Xu,Hanlin Cheng,Jiajun Gao,Xingmao Jiang,Chunxi Li,Weimin Yang
Poly(ethylene glycol) diacid [dcPEG, HOOCCH2(OCH2CH2)nOCH2COOH] can form a deep eutectic solvent (DES) with tetraethylammonium chloride (TEACl). The dcPEG-based DES (dcPEG-250/TEACl) as extractant (Ex) showed high performance for both basic and nonbasic N-species. In n-octane model oil, N-distribution coefficient [DN, (μgN·gEx–1)/(μgN·goil–1)] can be more than 100 for both indole and pyridine. In real oils, the DES was still effective (DN > 2.0; oil yield > 96.0%). The excellent performance was due to contributions of TEACl: (1) weakening the intermolecular interaction of dcPEG; (2) releasing Lewis basic −(OCH2CH2)n–; (3) intensifying polarity of the extractant. Extractive behaviors for the both N-species can be reflected by Freundlich- or Langmuir-like relationships between equilibrium N-contents in the extractant and the oil phases, respectively. It was interesting that, from dcPEG-250 to dcPEG-250/TEACl, the behaviors significantly changed. For the nonbasic, the extraction changed from chemical behavior with H-bonding to pseudo-physical one caused by solvent polarization. For the basic, it moved away from reactive behavior and changed to the chemical one involving acid–base interaction.
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
·
2013
·Vol. 25
·期 3
·723-731
·
IF 2.141
Shi Zhonggen,Guo Rui,Li Weichang,Zhang Yi,Xue Wei,Tang Yu,Zhang Yuanming
Chitosan (CS) was first modified hydrophobically with deoxycholic acid (DCA) and then with polyethylene glycol (PEG) to obtain a novel amphiphilic polymer (CS–DCA–PEG). This was covalently bound to folic acid (FA) to develop nanoparticles (CS–DCA–PEG–FA) with tumor cell targeting property. The structure of the conjugates was characterised using Fourier transform infrared and 1 H nuclear magnetic resonance spectroscopy and X-ray diffraction. Based on self-aggregation, the conjugates formed nanoparticles with a low critical aggregation concentration of 0.035 mg/ml. The anti-cancer drug doxorubicin (DOX) was encapsulated into the nanoparticles with a drug-loading capacity of 30.2 wt%. The mean diameter of the DOX-loaded nanoparticles was about 200 nm, with a narrow size distribution. Transmission electron microscopy images showed that the DOX-loaded nanoparticles were spherical. The drug release was studied under different conditions. Furthermore, the cytotoxic activities of DOX in CS–DCA–PEG–FA nanoparticles against folate receptor (FR)-positive HeLa cells and FR-negative fibroblast 3T3 cells were evaluated. These results suggested that the CS–DCA–PEG–FA nanoparticles may be a promising vehicle for the targeting anticancer drug to tumor cells.
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DOI
PubMed
高影响因子
Catalysis Science & Technology
·
2019
·Vol. 9
·期 23
·6749-6759
·
IF 5.726
Wei Chen,Tongyang Song,Jingxia Tian,Peng Wu,Xiaohong Li
Indirect CO2 conversion to ethylene glycol (EG) and methanol (ME) via CO2-derived ethylene carbonate (EC) as the intermediate is an attractive and promising approach. Cu-Based catalysts have been regarded as effective catalysts for the hydrogenation of EC to yield ME and EG. In this work, we prepared Cu/SiO2 catalysts through different methods for the hydrogenation of EC to yield ME and EG. The results show that Cu/SiO2-AE catalysts prepared by an ammonia evaporation (AE) method are superior to Cu/SiO2-DP catalysts prepared by a deposition–precipitation (DP) method. After modification using glucose with an optimal amount, the Cu8G1/SiO2-AE catalysts showed enhanced catalytic performance, furnishing 86% selectivity to ME and 99% selectivity to EG at almost full conversion of EC, with a TOF value for ME formation reaching about 39 h−1. A series of techniques such as N2 sorption, ICP-AES, FT-IR, H2-TPR, H2-TPD, TEM, and XPS were adopted to characterize the physicochemical properties of relevant catalysts. It was found that the Cu/SiO2-AE catalyst had a smaller Cu particle size. After modification with glucose, the Cu8G1/SiO2-AE catalyst had the smallest Cu particle size, the highest hydrogen adsorption ability, and the strongest interaction of Cu with SiO2 so that the highest Cu+/(Cu0 + Cu+) molar ratio was detected. In addition, upon investigation of catalyst stability and reusability, it was found that glucose modification for the Cu/SiO2-AE catalyst can also alleviate the deactivation distinctly.
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高影响因子
Nanoscale Research Letters
·
2018
·Vol. 13
·期 1
·1-10
·
IF 3.125
Cao Hongyan,Guo Fenghao,Chen Zhiyong,Kong Xiang Zheng
Stimuli-responsive polymers have received growing attention in recent years owing to their wide applications in diverse fields. A novel stimuli-responsive polymer, based on oligo(ethylene glycol) diacrylate (OEGDA) and methacrylic acid (MAA), P(OEGDA-MAA), is prepared by precipitation polymerization and is shown to have a LCST-type VPTT (volume phase transition temperature) at 33 °C in water and a UCST-type VPTT at 43 °C in ethanol, all at concentration of 1 mg/mL. Both VPTTs are strongly concentration and pH dependent, providing an easy way to tune the phase transition temperature. The polymer is characterized with regard to its composition and its morphology in water and in ethanol at different concentration. The two transitions are studied and interpreted based on the results. This work provides a novel way for the preparation of a new type of stimuli-responsive polymer with great potential for different applications, particularly those in biomedical areas because PEG-based stimuli-responsive polymers are known to be nontoxic and non-immunogenic.
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DOI
高影响因子
MATERIALS & DESIGN
·
2018
·
IF 4.525
Bing Cong,Youxin Song,Naiqing Ren,Gongshan Xie,Can Tao,Yiping Huang,Gewen Xu,Junjie Bao
An environmental friendly waterborne polyurethane (WPU) dispersion was synthesized from polyethylene glycol (PEG), hexamethylene diisocyanate (HDI), diethylene glycol (DEG) and dimethylol propionic acid (DMPA). Solid polymer electrolytes based on WPU and LiTFSI were fabricated via an organic solvent free process. The LiTFSI salts were found to be dissolved in WPU by the coordination of Li + ion with carbonyl and ether group in WPU. The as-prepared WPU showed a semi-crystalline structure and became amorphous after adding lithium salts. The ionic conductivities increased with the increase of salt concentration and followed the Arrhenius behavior. The 20 wt% LiTFSI in WPU electrolyte showed a superior comprehensive performance with an ionic conductivity of 7.3 × 10 −4 and 2.2 × 10 −3 S cm −1 at 60 °C and 80 °C. All-solid-state LiFePO 4 /SPE/Li cell using this electrolyte exhibited an initial discharge capacity of 151 mAh g −1 at 0.1C under 60 °C. All of these results demonstrate that this new WPU-based solid polymer electrolyte is a promising environmentally friendly candidate for all-solid-state lithium ion batteries .
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2025
·
IF 2.8
Mengyuan Li,Jinling Guo,Jiaming Ge,Jingwen Yao,Lin Ma,Zheng Li,Xiangli Han,Ming Liu,Fei Tian,Jing Zhao
The application prospects of magnetic nanocomposites in cancer treatment and diagnosis are extensive, as they enable targeted drug delivery to tumors. Herein, a novel therapeutic strategy was proposed for oral squamous cell carcinoma (OSCC), in which polyethylene glycol-folic acid (FA-PEG) was modified on nanocomposites by combining Fe 3 O 4 and layered double hydroxide (LDH) to obtain a drug carrier for the targeted delivery of the anticancer drug berberine (Ber). We have confirmed that FA-PEG/Fe 3 O 4 @LDH exhibited a high drug loading capacity for Ber and excellent biocompatibility. Moreover, it demonstrated remarkable pH-responsive drug release (Ber release of 3.87% and 53.77% within 48 h at pH 7.4 and 5.0, respectively). The cellular experiments demonstrated that FA-PEG/Fe 3 O 4 @LDH@Ber exhibited significant inhibition of cellular activity, while the targeted release of Ber effectively depleted the overexpressed GSH and promoted ROS generation, thereby facilitating oxidative stress and inducing mitochondrial dysfunction in CAL27 cells, thus promoting apoptosis of CAL27 cells. Therefore, FA-PEG/Fe 3 O 4 @LDH can be used as a potential pH-controlled release drug delivery system which has great significance for the targeted therapy of OSCC.
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Ping Jiang,Zhenyu Lei,Liang Chen,Xuecheng Shao,Xinmiao Liang,Jun Zhang,Yanchao Wang,Jiujun Zhang,Zhaoping Liu,Jiwen Feng
Vanadium hexacyanoferrate (VHCF) with an open-framework crystal structure is a promising cathode material for rechargeable aqueous metal-ion batteries owing to its high electrochemical performance and easy synthesis. In this paper, vanadium hexacyanoferrate cathodes were first used for constructing rechargeable aqueous sodium-ion batteries (VHCF/WO3) and tested in the new-type electrolyte (NaP-4.6) consisting of a polyethylene glycol (PEG)/H2O/NaClO4 electrolyte with a low H+ concentration (molar ratio of [H2O]/[Na+] is 4.6), which has high stability at a high current density as high as 1000 mA g–1 with a capacity retention of 90.3% after 2000 cycles at high coulombic efficiency (above 97.8%). To understand their outstanding performance, the proton-assisted sodium-ion storage mechanism and interphase chemistry of VHCF are investigated by solid-state NMR (ssNMR) technology. It is suggested that the H+ storage reaction is accompanied by the redox of vanadium atoms and Na+ intercalation is accompanied by the redox of iron atoms. It is also observed that the complex of polyethylene glycol (PEG) with Na+ (PEG–Na+) exists on the VHCF surface, which facilitates the stability of VHCF and promotes the alkali-ion transfer at a high current density. The results of the ssNMR study offer new insights into the intercalation chemistry of Prussian blue analogues with open-framework-structured compounds, which can greatly broaden our horizons for battery research.
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2022
·
IF 10.53
Guoxiu Wang,Yonglei Chen,Congjie Pan,Hongli Chen,Sanyuan Ding,Xingguo Chen
Owing to their high specific surface area , tunable pore sizes, excellent chemical/thermal stability and ability to allow easy modification of the nature of the surface, covalent organic frameworks (COFs) have shown great promise in membrane separation . However, until now, rapid preparation of self-standing COFs membrane has still been a great challenge. In this work, a polyethylene glycol-assisted space-confined strategy for rapid and simple synthesis of imine-linked self-standing COF (TB-DA COF) membranes was developed for the first time. By using this strategy, the molecular organic building unit 1,3,5-tri-(4-aminophenyl)benzene (TB) is confined in a thin layer of polyethylene glycol in conjunction with molecular organic building unit 2,5-dimethoxyterephthalaldehyde (DA). Therefore, the condensation reaction between TB and DA can occur directly without slow diffusion process. In addition, the amorphous-to-crystalline interconversion process can be completed rapidly. Based on this, the imine-based TB-DA COF membrane with high crystallinity can be synthesized within 2 min, which has been the fastest strategy for preparation of COFs membrane to date. The synthesized TB-DA COF 2 membrane showed an excellent rejection (>96%) for dye molecules. This work opens a new fabrication route for COF-based membranes.
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高影响因子
CHINESE CHEMICAL LETTERS
·
2014
·
IF 1.178
Chang-Lei Liu,Gang Wu,Si-Chong Chen,Jiao You,Yu-Zhong Wang
Poly( p -dioxanone)-block-polyethylene glycol diblock copolymers functionalized with pyrene moieties (Py-PPDO-b-PEG) at the chain ends of PPDO blocks were synthesized for preparing anisotropic micelles with improved stability. The micellization and crystallization of the copolymers were investigated by nano differential scanning calorimetry (Nano DSC), transmission electron microscopy (TEM), UV–vis spectrophotometery, fluorophotometer, and dynamic light scattering (DLS), respectively. The results indicated that the aggregation of pyrene induced by intermolecular interaction lead to micellization of Py-PPDO-b-PEG at much lower concentrations than those of PPDO-b-PEG copolymers without pyrene moieties. The aggregation of pyrene moieties may also serve as nucleation agent and therefore enhance the crystallization rate of PPDO blocks. Fluorescence measurements by using Nile Red as the fluorescent agent indicated that the micelles of Py-PPDO-b-PEG have high stability and load capacity for hydrophobic molecules.
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高影响因子
Acta Biomaterialia
·
2016
·
IF 6.008
Jiang Wu,Zecong Xiao,Chaochao He,Jingjing Zhu,Guanglong Ma,Guangzhi Wang,Hongyu Zhang,Jian Xiao,Shengfu Chen
Nonfouling materials such as neutral poly(ethylene glycol) (PEG) and zwitterionic poly(sulfobetaine methacrylate) (pSBMA) are ideal biocompatible materials for drug, especially protein drug delivery. The interaction behavior of protein between the nonfouling materials could cause great impact on their future applications, such as controlled release drug delivery systems. In this work, we investigated the diffusion behavior of the fluorescence-labeled model proteins (bovine serum albumin (BSA) and lysozyme (LYZ)) in nonfouling PEG, pSBMA and mixed PEG-SBMA hydrogels (SBMA:PEG 4:1, SBMA:PEG 1:4). It was observed that these four hydrogels showed varied diffusion behavior for either negatively charged BSA or positively charged LYZ due to protein-polymer interaction and the free water content in hydrogel matrix. The relatively stronger interaction between protein-PEG than protein-pSBMA could increase protein loading efficiency and control release rate by changing ratio of PEG to SBMA in the hybrid hydrogel. Moreover, it is further demonstrated the free water (freezable water) content in low cross-linked hydrogel, not the equilibrium water content (EWC), is a more accurate parameter to reflect the diffusion behavior of protein molecules . Thus, these results together provide new insights of the interactions between protein molecules and nonfouling polymers as well as the bio applications of the nonfouling polymeric hydrogels. Statement of Significance This work shows that the relative stronger interaction between protein-PEG than protein-pSBMA could increase protein loading efficiency and control release rate by the change ratio of PEG to SBMA in the hydrogel, while the free water (freezable water) content in low cross-linked hydrogel, not the equilibrium water content (EWC), is a more accurate parameter to reflect the diffusion behavior of protein molecules. The impact of this work (i) gains some new insights of the interactions between protein molecules and nonfouling polymer matrixes for protein drug delivery; (ii) prompts to apply the weak PEG-protein interactions to protein drug loading and release; (iii) provides a new fundamental understanding of free water in hydrogel for protein diffusion.
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高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2017
·Vol. 164
·期 6
·A1321
·
IF 3.259
Chaolumen Wu,Taoran Li,Chenbo Liao,Qingkai Xu,Yuancheng Cao,Lei Li,Jun Yang
Triethylene glycol dimethyl ether (G3) is evaluated as an electrolyte solvent for non-aqueous lithium-oxygen (Li-O2) batteries. A liquid electrolyte of 1 M LiTFSI in G3 shows lower viscosity, higher oxygen solubility and diffusion, higher ionic conductivity and lithium ionic transference number compared to the conventional liquid electrolyte of 1 M LiTFSI in tetraethylene glycol dimethyl ether (G4). Then the Li-O2 battery using the G3-based electrolyte shows better cycling stability and higher rate capability compared to the battery using the G4-based electrolyte. At a higher current density of 2.5 A gcarbon−1, the discharge capacity of the battery using the G3-based electrolyte is about 1472 mAh gcarbon−1, which is about four times higher than that of the battery using the G4-based electrolyte. At current density of 1 A gcarbon−1 with a fixed capacity of 1000 mAh gcarbon−1, the battery using the G3-based electrolyte can be operated stably for 80 cycles, while only 20 cycles are achieved by using the G4-based electrolyte. Therefore, we think the G3-based electrolyte could be a proper alternative electrolyte to the conventional G4-based electrolyte for the development of Li-O2 batteries.
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高影响因子
危险品化学品经营许可证（带存储）