ANALYTICAL LETTERS
·
2024
·
IF 1.6
Xuerui Lou,Minglei Li,Weiwei Guo,Yingjie Fu,Hui Xi,Peng Li,Wuduo Zhao,Shihao Sun
Electronic cigarettes (E-cigarettes) have become popular around the world. An important reason is the variety of available flavors. However, many countries have imposed restrictions on flavor substances in E-cigarettes due to their potential health risks. Therefore, it is necessary to develop an effective way to identify flavorings in E-cigarette liquids. In this work, direct analysis in real time-mass spectrometry (DART-MS) in the quick strip (QS) mode was developed and applied to determine flavorings in the E-cigarettes. Vanillin, ethyl vanillin, maltol, and ethyl maltol were quantified. Meanwhile, the ionization efficiency of flavorings in the different solvents was compared in the QS mode, which revealed that the solvent boiling point was related to the analyte ionization efficiency. The effect of endogenous matrix (propylene glycol and glycerol) on flavoring ionization was also investigated. Calibration curves with satisfactory linearity (R2 > 0.99) were established from 1 to 1000 μg L−1. Good sensitivity (limits of detection [LODs] < 0.3 μg L−1), recoveries (92.6% to 104.7%), and acceptable repeatability (relative standard deviations < 14.6%, n = 5) were obtained. The limits of quantification (LOQs; 10–50 μg g−1) for the E-cigarette liquid sample were much lower than the regulatory limits. The developed method provided a simple way for rapidly determining flavorings in E-cigarettes.
✓ 已验证
产品关联
DOI
高影响因子
Insects
·
2021
·Vol. 12
·期 1
·68
·
IF 2.769
Xiaojian Wen,Kailang Yang,Jaime C. Piñero,Junbao Wen
Simple SummaryEucryptorrhynchus scrobiculatus(Motschulsky) andE. brandti(Harold) are significant pests of tree of heaven,Ailanthus altissima, often leading to tree death. Monitoring systems that involve host–plant based attractants need to be developed for both insect pest species. Here, we compared the behavioral and electrophysiological responses ofE. scrobiculatusandE. brandtito volatiles emitted by various parts of the host plant. Host plant-derived volatiles showed to play a greater role in the foraging behavior ofE. brandtithan inE. scrobiculatus. Volatile components of phloem were found to be particularly attractive toE. brandti.AbstractEucryptorrhynchus scrobiculatusandE. brandti(Coleoptera: Curculionidae) are host-specific pests ofAilanthus altissima(Mill.) Swingle (Sapindales: Simaroubaceae), causing extensive damage to the host. There are no effective attractants available for pest management. The main aim of this study was to explore the role of host plant-derived volatiles in the behavioral response of both weevil species. In a field experiment, both weevil species showed positive response to phloem, and there was no preference for phloem associated with healthy or injured trees. Significantly moreE. brandtiadults responded to the olfactory treatments compared toE. scrobiculatus. In a large-arena experiment, both males and females ofE. scrobiculatussignificantly preferred phloem from the tree trunk while adults ofE. brandtiresponded in significantly greater numbers to tree limbs than to any other parts of host. Females and males ofE. scrobiculatusresponded positively to all parts of host tested in the Y-tube bioassay, whileE. brandtiadults were only attracted by the phloem from healthy and injured trees. There were dissimilar electroantennographic responses to compounds such as 1-hexanol and (1S)-(−)-β-pinene between the two weevil species. This study represents the first report documenting behavioral and electrophysiological responses ofE. scrobiculatusandE. brandtito volatiles from various parts ofA. altissimaand findings may aid efforts to develop attractants.Keywords:host plant volatiles;semiochemical;feeding selection;behavior;physiology
✓ 已验证
DOI
PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2018
·Vol. 410
·期 23
·5871-5878
·
IF 3.307
Wang Yu,Cui Min,Jiao Mingxia,Luo Xiliang
Accurate detection of protein biomarkers in complex media remains a challenge due to severe nonspecific adsorption and biofouling, and sensing interfaces that combine the high sensitivity and antifouling ability are highly desirable. Herein, an antifouling sensing interface capable of sensitively assaying immunoglobulin E (IgE) in biological samples was constructed. The sensing interface was fabricated through the self-assembly of a zwitterionic peptide and the IgE aptamer onto a macroporous Au substrate, which was electrochemically fabricated with the aid of multilayer polystyrene nanospheres self-assembled on glassy carbon electrode. Due to the huge surface area arising from porous morphology and high specificity of aptamer, the developed electrochemical biosensor exhibits ultrahigh sensitivity and selectivity towards IgE, with the linear range of 0.1–10 pg mL −1 , and a very low limit of detection down to 42 fg mL −1 . Interestingly, owing to the presence of the zwitterionic peptide, the biosensing interface can satisfyingly reduce the nonspecific adsorption and fouling effect. Consequently, the biosensor was successfully applied to detect IgE in complex biological samples, indicating great promise of this peptide-based sensing interface for antifouling assays.
ᅟ
✓ 已验证
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Wentao Ma,Wei Liu,Chao Yuan,Bo Cui,Yaqi Liu,Li Guo,Bin Yu,Meng Zhao,Feixue Zou
To overcome the limitations of conventional vitamin E (VE) delivery systems, a double-package system comprising κ-carrageenan hydrogels and VE/highly branched cyclodextrin (HBCD) composites was developed and systematically evaluated for structural characteristics and release behavior. The results demonstrated that HBCD encapsulation of VE formed stable composites with high encapsulation efficiency (81.72 %) and thermostability (325.86 °C), which facilitated the ordered alignment and helical aggregation of κ-carrageenan chains to build a continuous and uniform hydrogel network. The 2 % composites within the κ-carrageenan network strengthened hydrogen-bond interaction and generated a secondary micro-network, thereby enhancing structural integrity (758.39 Pa) and freeze–thaw stability (a 30 % reduction in syneresis) of the double-package system. Importantly, the inner–outer network effectively protected VE under gastric conditions and enabled controlled intestinal release (> 60 %). Overall, this study underscores the potential of HBCD as a wall material and provides a strategy for the design of double-package delivery systems.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Bioresources and Bioprocessing
·
2025
·Vol. 12
·期 1
·1-16
·
IF 5.1
Deng Jie,Zheng Jia,Li Xing,Huang Dan,Ye Guangbin,Luo Huibo
Qu -aroma is a critical quality indicator for medium–high temperature Daqu (MT- Daqu ). Due to the differences in regional and environmental conditions, these differences are likely to cause variations in the Qu -aroma of MT- Daqu . Despite this, comprehensive research on the variations in Qu -aroma across different regions has been lacking. This study aims to address this gap to analyze the differences in Qu -aroma characteristics of MT- Daqu from seven distinct production areas. Sensory analysis identified seven broad aroma categories and 25 specific aromas characterizing the Qu -aroma of MT- Daqu samples. Chen aroma and roasted aroma were notably more prevalent in MT- Daqu samples from Sichuan compared to those from other regions ( P < 0.05 ). In total, 123 volatile compounds were detected in MT- Daqu , with 42 classified as aroma-active compounds. Among these, 21 aroma-active compounds were identified as markers distinguishing Sichuan MT- Daqu from those produced in non-Sichuan regions, showing significant differences in their concentrations ( P < 0.05 ). Additionally, six major aroma-active compounds were found to significantly contribute to the aroma differences between Sichuan and non-Sichuan MT- Daqu . This study delineates the distinct Qu -aroma characteristics of MT- Daqu from various SAB production areas. The insights gained from this research offer valuable guidance for optimizing flavor profiles in MT- Daqu production. Graphical
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF FIRE SCIENCES
·
2018
·
IF 1.296
Daikun Jia,Jiyu He,Rongjie Yang
DOPO and its derivatives are excellent phosphorus-based flame retardants, which are applied to a series of polymer materials. In this article, a DOPO derivative bearing an active terminal epoxy group was synthesized using a non-solvent method. Fourier transform infrared spectroscopy, nuclear magnetic resonance, mass spectrometry, ultra-performance liquid chromatography, differential scanning calorimetry, thermogravimetric analysis, and viscosity measurements were performed to determine its molecular structure, purity, thermal performance, and fluidity. A possible fragmentation mechanism of the as-prepared DOPO derivative was analyzed using electron ionization mass spectrometer. All the results indicate that the synthesis was successful and the product had satisfactory purity and its initial decomposition temperature (T5%) under nitrogen and air atmosphere was 246°C and 240°C, respectively. Then, as a comparison with dimethyl methyl phosphonate, triethyl phosphate, and DOPO, e-DOPO was applied to a rigid polyurethane foam to investigate its effect on the flame retardancy, thermal stability, and cell morphology of polyurethane foam by limiting oxygen index, cone calorimetry, thermogravimetric analysis, and scanning electron microscopy. The results indicate that e-DOPO has a greater effect than DOPO and can effectively reduce the heat release and smoke release and improve the limiting oxygen index and thermal performance of the polyurethane foam. The cell size of the sample containing e-DOPO was more uniform.
✓ 已验证
DOI
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2020
·
IF 4.006
Shuang Gu,Wei Chen,Zhenhe Wang,Jun Wang,Yujia Huo
This study described the rapid detection of milled rice infected with Aspergillus spp. species based on headspace-gas chromatography ion-mobility spectrometry (HS-GC-IMS) and electronic nose (E-nose) combined with chemometrics, namely principal component analysis (PCA), k-nearest neighbor (kNN) and partial least squares regression (PLSR). 3D HS-GC-IMS imaging and their response differences enabled the discrimination among fungal species. kNN was used to differentiate rice samples with cdifferent levels of fungal infection and achieved correct classified rate of 94.44% and 91.67% by HS-GC-IMS and E-nose, respectively. PLSR method was used for quantitative regression of fungal colony counts in rice samples and good prediction performances were achieved by HS-GC-IMS (R p 2 = 0.909, RMSEP = 0.202) and E-nose (R p 2 = 0.864, RMSEP = 0.235). The results indicated that both HS-GC-IMS and E-nose approaches can potentially be implemented for the detection of fungal contamination levels in milled rice, and HS-GC-IMS fingerprinting coupled with chemometrics might be used as an alternative tool for a highly sensitive method. This research might provide scientific information on the rapid, non-destructive, and effective fungal detection system for rice grains .
✓ 已验证
DOI
高影响因子
CHEMOSPHERE
·
2021
·
IF 7.086
Yan Yan,Yang Deng,Wenjing Li,Wei Du,Yangyang Gu,Jiayi Li,Xiaoguang Xu
The selection of aquatic plants at different growth stages and their absorption, migration, and transformation mechanisms has yet to be clarified. In this study, Eichhornia crassipes at the seedling and mature stages were selected to uptake antibiotics under hydroponic conditions. The results showed that the enrichment of ciprofloxacin (CIP) in roots at the seedling and mature stages were 7.72～2114.39 μg g −1 and 0.07～3711.33 μg g −1 , respectively. The enrichment of CIP in aerial parts at the seedling and mature stages were 16.38～24.24 μg g −1 and 9.55～20.13 μg g −1 , respectively. The translocation from roots to aerial parts at the seedling stage was high, as evidenced by the relatively higher transfer factor (TF). In addition, eight and ten major metabolic products were observed in the tissues of seeding and mature stage of E. crassipes , respectively. The metabolic pathway of CIP was short at the maturity stage, and CIP had a strong upward migration ability at the seedling stage, facilitating long-time photodegradation . However, E. crassipes exhibited a poor CIP tolerance at the mature stage and decayed relatively early. Therefore, the seedling stage of E. crassipes was proposed to be applied for phytoremediation , and these findings might improve the ability to phytoremediation of antibiotic-contaminated water.
✓ 已验证
DOI
高影响因子
Analytical Methods
·
2021
·Vol. 13
·期 19
·2209-2214
·
IF 2.896
Yuan Yao,Guoming Xie,Xin Zhang,Jinshan Yuan,Yulei Hou,Hui Chen
Biosensors based on nanomaterials are becoming a research hotspot for the rapid detection of pathogenic bacteria. Herein, a “turn-on” fluorescent biosensor based on a FRET system was constructed for the fast detection of a representative pathogenic microorganism, namely, E. coli, which causes most urinary tract infections. This biosensor was constructed by utilizing synthesized UCNPs as fluorescent donors with stable luminescence performance in complex biological samples and GO@Fe3O4 as a receptor with both excellent adsorption ability and fluorescence quenching ability. A specific ssDNA selected as an aptamer which could recognize E. coli was immobilized on the UCNPs to form UCNP-Apt nanoprobes. The nanoprobes were adsorbed on the surface of GO@Fe3O4 through the π-stacking interactions between aptamers and GO. In the presence of E. coli, UCNP-Apt nanoprobes detached from GO@Fe3O4 due to the specific recognition of aptamers and bacteria, resulting in obvious fluorescence recovery, and the concentration of bacteria was positively correlated with the intensity of the fluorescence signal; such a “turn-on” signal output mode ensures excellent precision. In addition, the easy magnetic separation of GO@Fe3O4 simplifies the operation process, helping the sensor detect bacteria in 30 minutes with a linear range from 103 to 107 CFU mL−1 and a limit of detection of 467 CFU mL−1. Moreover, recovery test results also showed that the sensor has clinical application potential for the rapid detection of pathogenic microorganisms in complex biological samples.
✓ 已验证
DOI
PubMed
高影响因子
Advanced Science
·
2024
·Vol. 11
·期 34
·2400234
·
IF 14.3
Senlin Hou,Qingyun Huang,Hongyu Zhang,Qingjiu Chen,Cong Wu,Mengge Wu,Chen Meng,Kuanming Yao,Xinge Yu,Vellaisamy A. L. Roy,Walid Daoud,Jianping Wang,Wen Jung Li
The dense mechanoreceptors in human fingertips enable texture discrimination. Recent advances in flexible electronics have created tactile sensors that effectively replicate slowly adapting (SA) and rapidly adapting (RA) mechanoreceptors. However, the influence of dermatoglyphic structures on tactile signal transmission, such as the effect of fingerprint ridge filtering on friction-induced vibration frequencies, remains unexplored. A novel multi-layer flexible sensor with an artificially synthesized skin surface capable of replicating arbitrary fingerprints is developed. This sensor simultaneously detects pressure (SA response) and vibration (RA response), enabling texture recognition. Fingerprint ridge patterns from notable historical figures – Rosa Parks, Richard Nixon, Martin Luther King Jr., and Ronald Reagan – are fabricated on the sensor surface. Vibration frequency responses to assorted fabric textures are measured and compared between fingerprint replicas. Results demonstrate that fingerprint topography substantially impacts skin-surface vibrational transmission. Specifically, Parks' fingerprint structure conveyed higher frequencies more clearly than those of Nixon, King, or Reagan. This work suggests individual fingerprint ridge morphological variation influences tactile perception and can confer adaptive advantages for fine texture discrimination. The flexible bioinspired sensor provides new insights into human vibrotactile processing by modeling fingerprint-filtered mechanical signals at the finger-object interface.
✓ 已验证
DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2026
·
IF 8.8
Siyan Liu,Heyu Pan,Yanchao Mao,Feifei Wang,Na Zhang,Shuyi Li,Zhenzhou Zhu
Chlorella pyrenoidosa is a promising plant-based protein source , whereas the volatile off-flavours derived from lipid oxidation substantially limit consumer acceptance. Selenium (Se) is recognised as a beneficial trace element that can improve flavour characteristics in plants by enhancing antioxidant capacity. This study investigated the effects of Se supplementation (0–2 mg/L) on the volatile profile of C. pyrenoidosa and explored the underlying mechanisms. E-nose analysis revealed significant differences in flavour profile among the treatments. GC–IMS and GC–MS identified 25 and 28 volatile organic compounds (VOCs), respectively. Fifteen key aroma compounds were screened by orthogonal partial least squares discriminant analysis (OPLS–DA), random forest (RF) modelling, and odour activity value (OAV) and relative OAV (ROAV) calculations. Notably, 0.50 mg/L Se was identified as the optimal enrichment concentration, as it improved overall flavour quality by reducing aldehyde accumulation, particularly hexanal. This improvement was attributed to Se-mediated reductions in lipid content and enhanced antioxidant capacity, as evidenced by increased glutathione peroxidase (GPx) activity, reduced reactive oxygen species (ROS) levels, and alleviated lipid peroxidation, alongside decreased lipoxygenase (LOX) and hydroperoxide lyase (HPL) activities by 60.08% and 37.31% respectively, thereby inhibiting the formation of off-flavour VOCs. Overall, this study provides the first evidence that Se modulates the flavour profile of C. pyrenoidosa and preliminarily elucidates the mechanism by which appropriate Se supplementation improves flavour quality through reshaping biochemical composition, maintaining redox homeostasis, and regulating key enzymes involved in aldehyde biosynthesis. These findings offer a theoretical foundation for developing novel functional microalgal-based foods.
✓ 已验证
产品关联
DOI
高影响因子
Clinical and Translational Medicine
·
2026
·Vol. 16
·期 2
·e70619
·
IF 7.9
Yifan Ren,Yuxuan Lu,Qing Cui,Hao Shang,Meng Fan,Yun Sun,Xiali Shi,Rongqian Wu,Hongwei Lu
During AP, MFG‐E8 expression in pancreatic acinar cells is downregulated, resulting in disruption of the ABCE1/MFG‐E8 complex. This impairment leads to defective mitophagy flux, accumulation of lipid peroxides, endoplasmic reticulum stress and ferroptosis, ultimately contributing to pancreatic damage .
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）