TALANTA
·
2021
·
IF 6.057
Nan Jiang,Peng Li,Shihao Sun,Wei Wei
Since 5-hydroxymethylfurfural (HMF) becomes a neo-forming contaminant with latent harm to human health, development of new method for highly sensitive detection of HMF is extremely desirable. Herein, a novel ratiometric fluorescence sensor based on strand displacement reaction and magnetic separation was designed for sensitive and selective detection of HMF with the help of MnO 2 nanosheets . The aldehyde-functionalized DNA (S0–CHO) and HMF competed for binding to amino-functionalized magnetic beads (NH 2 -MBs). Then, S0–CHO was collected from supernatant by magnetic separation. In the presence of HMF, the obtained S0–CHO induced the formation of T-shaped DNA by strand displacement reaction (SDR), lighting the fluorescence of FAM. In the absence of HMF, no S0–CHO was present to ignite T-shaped DNA. In this situation, fluorescence of Cy5 was turned on. Thus, a ratiometric fluorescence sensor for high-sensitive detection of HMF was developed. The sensor has a wide linear range from 5 nM to 5 μM. It also exhibited high selectivity against other potential interfering substances. It has been successfully applied to analyze HMF in food samples. The method has potential to be expanded to detect other molecules containing aldehyde groups and further be applied in food safety, environment and other fields.
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DOI
高影响因子
Waste and Biomass Valorization
·
2017
·Vol. 9
·期 11
·2181-2190
·
IF 1.337
Han Bin,Zhao Peng,He Rong,Wu Tinghua,Wu Ying
A series of supported B 2 O 3 /ZrO 2 –Al 2 O 3 (BZA) catalysts with different loading B 2 O 3 were prepared and characterized by XRD, FT-IR, XPS, NH 3 -TPD, N 2 adsorption–desorption and FT-IR (pyridine adsorption). These catalysts were applied for direct conversion of glucose to 5-hydroxymethylfurfural (HMF). An optimized HMF yield of 41.2% at a glucose conversion of 90.8% was obtained within 4 h at 150 °C over B 2 O 3 (20 wt%)/ZrO 2 –Al 2 O 3 (BZA-0.20). The best catalytic performance of BZA-0.20 was associated with the highest amount of total acid. The simultaneously bearing Lewis acid and Brønsted acid sites were more efficient for production of HMF from glucose.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Baoxia Liu,Haoshuang Shen,Daosheng Liu,Yuanqiang Hao,Xu Zhu,Qi Shen,Peng Qu,Maotian Xu
Metal-organic coordination polymers have emerged as attractive functional materials due to their tunable structures and unique properties. In this work, by the self-assembly of citrate (Cit) and lanthanide ions, we developed lanthanide coordination polymer nanoparticles (LCPNPs), Cit/Tb, for fluorescence sensing of guanosine-5-monophosphate (GMP). The LCPNP-based Cit/Tb sensor alone displayed weak luminescence, however, the addition of GMP to Cit/Tb led to the formation of a ternary LCPNP, Cit/Tb-GMP, with a significantly enhanced luminescence (15-fold) owing to the intramolecular energy transfer from GMP to Cit/Tb and the hydrophobic environment in the polymer interior. This luminescence turn-on assay exhibited excellent selectivity and high sensitivity for GMP with detection limit of 100 nmol L −1 . Furthermore, the Cit/Tb LCPNP possesses a long luminescence lifetime of up to a millisecond, which is important for detecting GMP in complicated samples of infant formula and ham by time-resolved fluorimetry. We believe that the presented Cit-based nanosensor would inspire the development of various new LCPNP-based fluorescent assays by utilizing Cit or other water-soluble, non-toxic organic ligands for a variety of applications in fluorescence sensing, bio-imaging, drug delivery and so on.
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高影响因子
CHINESE JOURNAL OF CATALYSIS
·
2014
·
IF 1.552
Xingcui Guo,Xicheng Wang,Jing Guan,Xiufang Chen,Zhangfeng Qin,Xindong Mu,Mo Xian
Ru particles were introduced into the zeolite ZSM-5 (MFI) by either a conventional impregnation method or a one-step template-free process. The resultant materials were characterized by X-ray diffraction, N 2 adsorption-desorption, scanning electron microscopy, transmission electron microscopy, NH 3 and CO 2 temperature-programmed desorption. The results indicated that the Ru species in ZSM-5 catalysts prepared via the latter approach (designated as Ru/ZSM-5-TF) were highly dispersed in the ZSM-5 framework structure and this material exhibited high catalytic performance during the hydrogenation of D-glucose to D-sorbitol. The conversion of D-glucose was as high as 99.6% with D-sorbitol selectivity reaching 99.2%, exceeding the performance of Ru/ZSM-5 catalysts prepared by the conventional impregnation method with microporous or desilicated ZSM-5 supports. More importantly, this catalyst showed high stability against leaching and poisoning and could be reused several times. The extensive dispersion of the Ru species, strong interaction between the Ru species and the ZSM-5, and the suitable surface acidity-basicity balance of the Ru/ZSM-5-TF were all critical factors leading to excellent catalytic behavior and stability.
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高影响因子
Small
·
2021
·Vol. 17
·期 46
·2103374
·
IF 13.281
Xiaowei Yu,Kaikai Liu,Hongyue Zhang,Bolun Wang,Wenyan Ma,Jiyang Li,Jihong Yu
Multilevel luminescence materials have aroused wide attention for their advanced anti-counterfeiting abilities. However, various complicated stimuli factors involved in multilevel luminescence anti-counterfeiting (MlLA) limit the practical applications of such materials. Herein, carbon dots (CDs) are in situ introduced into Eu-substituted AlPO 4 -5 zeolite (named CDs@EuAPO-5) via a solvent-free thermal crystallization method, which exhibits triple emissions including pink fluorescence mainly associated with Eu 3+ in the zeolite framework, blue fluorescence and green room temperature phosphorescence (RTP) associated with CDs. CDs are uniformly embedded in the EuAPO-5 zeolite matrix. Such composite displays excellent photo-, thermo-, and solvent resistance, as well as long-term storage-stability. Moreover, the triple emissions of the composite only need two kinds of common excitation lights to trigger, without involving other complicated stimuli. A triple-level luminescence anti-counterfeiting (TlLA) label has been built, realizing facile, quick, and advanced luminescence anti-counterfeiting that is hard to copy.
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高影响因子
APPLIED CATALYSIS A-GENERAL
·
2018
·
IF 4.521
Jingjie Cao,Mingwei Ma,Jinchan Liu,Yongquan Yang,Hui Liu,Xingliang Xu,Jiahui Huang,Huijuan Yue,Ge Tian,Shouhua Feng
Aluminum ion-exchanged Ca-montmorillonite with different concentrations of aluminum ion were prepared and applied in the conversion of carbohydrates to 5-hydroxymethylfurfural (HMF). It was found that two types of acid sites were present in the catalyst, Lewis acid sites for isomerization of glucose and Brønsted acid sites for dehydration of fructose. With Al-mont-10 as catalyst, the yield of HMF converted from glucose was 80.4% in a biphase system (THF: NaCl solution) at 180 °C for 2.5 h. Further, the catalyst also shows excellent catalytic performance in the conversion of starch and inulin, and the yield of HMF reached 60.1% and 81.6% under identical conditions, respectively.
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DOI
高影响因子
ACS Applied Nano Materials
·
2021
·
IF 5.097
Zhongwen Dong,Chuanyu Yang,Dongpu Zhao,Yanan Wang,Weifeng Chu,Zhaochi Feng,Xiangxue Zhu,Wenjie Xin,Yongchen Shang,Shenglin Liu,Longya Xu
The interzeolite transformation approach has been used extensively for the quick synthesis of zeolites at a lower cost. Herein, an interzeolite transformation method for the quick synthesis of co-crystalline ZSM-5/ZSM-11 (CDM-5) nanoaggregates has been developed by precisely controlling the synthesis parameters and using 1,6-hexamethylenediamine as an organic structure-directing agent. In contrast, the irregular CDM-5 zeolite block obtained from an amorphous aluminosilicate gel takes a longer crystallization time using the conventional method. Combined with the related results of characterization, UV-Raman spectra show that double 6-membered rings in the parent USY zeolite framework are broken, and an ordered aluminosilicate aggregate species (OAAS) containing 4-membered rings (4Rs) are formed during the interzeolite transformation. HRTEM and SEM images demonstrate that the block OAAS is dissolved into amorphous nanoparticles, followed by converting into CDM-5 nanoaggregates. These results reveal that an OAAS is essential for the synthesis of CDM-5 nanoaggregates via the interzeolite transformation method. In addition, the CDM-5 nanoaggregate catalyst exhibits superior stability and resistance to carbon deposition in the alkylation reaction of benzene with ethanol compared with the irregular block CDM-5 catalyst.
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高影响因子
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2021
·
IF 6.064
Xiaoling Qu,Guangyuan Zhou,Rui Wang,Haiyan Zhang,Zhipeng Wang,Min Jiang,Jun Tang
In pursuit of poly(ethylene 2,5-furandicarboxylate) PEF materials with high molecular weight, satisfactory appearance and faster crystallization rate, its preparation from dimethyl furan-2,5-dicarboxylate (DMFD) with ethylene glycol (EG) in the trace presence of metal zinc was performed via transesterification method. Optimization of the main polymerization parameters enabled Zn-catalyzed PEF to gain high molecular weight ( M n , 5.40 × 10 4 g mol −1 ) and low content of diethylene glycol furandicarboxylate unit (DEGF, 2.91%). On the basis of experimental phenomena and high performance liquid chromatography (HPLC), the actual catalytic active species of metal zinc in the polymerization was speculated to be a salt of 2, 5-furandicarboxylate derivative (Zn(II)). The in-stiu catalyst can efficaciously inhibit the influence of by-product FDCA on the color of PEF, which displayed quite better appearance (close to white). Differential Scanning Calorimetry (DSC) showed that the in-stiu catalytic system acted as nucleating agent (NA) and the crystallization half-time (t 1/2 ) of PEFs-Zn was only 1/4 of that of PEF-tin. Additionally, series of high molecular weight furan-based polyesters from DMFD and diols with different methylene (3, 5, 6 and 8) were obtained by zinc powder as in-stiu catalyst, which further evidenced it to be efficiency and universality.
研究领域:
材料科学
·
聚合物化学
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DOI
高影响因子
FLUID PHASE EQUILIBRIA
·
2019
·
IF 2.514
Xianming Zhang,Yufeng Hu,Weiting Ma,Jianguang Qi,Shuqin Mo
The salt effect on vapor–liquid phase equilibrium (VLE) has potential applications in industrial production of 1,3,5-trioxane. Optimizing reactive distillation process and developing new catalysts for industrial production of 1,3,5-trioxane require a reliable model for VLE of the reaction mixtures. Here an extended UNIFAC model combined a Debye–Hückel type is developed to describe the vapor–liquid and chemical equilibria of the multi-solvent salt-containing reactive mixtures associated with the 1,3,5-trioxane synthesis. New experimental data for the VLE of the quinary systems (formaldehyde + 1,3,5-trioxane + methanol + salt + water) and their ternary subsystems (1,3,5-trioxane + salt + water), (methanol + salt + water), and (formaldehyde + salt + water) are systematically measured at atmospheric pressure. The salts considered include LiCl, NaCl, KCl, NaBr, MgSO 4 , MgCl 2 , and Na 2 SO 4 . The model parameters, which are either obtained from the literature or determined from the VLE data of the above-mentioned ternary systems , are used to provide predictions for the quinary systems (formaldehyde + 1,3,5-trioxane + methanol + salt + water). The agreements between measured and predicted results are accurate. Furthermore, the model is used to uncover the effects of the salts considered on the VLE of these chemical reactive systems. The results show that MgSO 4 is a potential additive that can be used to improve the vapor–liquid phase separation during the reactive distillation process of 1,3,5-trioxane production.
研究领域:
化学工程
·
物理化学
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DOI
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Microbial Biotechnology
·
2025
·Vol. 18
·期 11
·e70257
·
IF 5.2
Hui Chen,Fengjiao Wang,Shengjie Li,Longxian Lv,Hao Xu,Jiafeng Xia,Lvwan Xu,Ding Shi,Lanjuan Li
Pediococcus pentosaceus Li05, a strain of lactic acid bacteria isolated from the faeces of healthy volunteers, exhibited potential protective effects against various diseases. This study performed third-generation sequencing and detailed characterisation of its genome. The Li05 chromosome harboured conserved genes associated with acid resistance ( atp ), bile salt resistance ( bsh ), oxidative stress resistance ( hsl , dltA , and et al.), and adhesion ( nrd , gap , and et al.), whereas the plasmid did not contain antibiotic resistance or virulence genes. Following intervention with Li05 in loperamide-induced constipated mice, constipation symptoms improved. Meanwhile, alterations in gut microbiota, increased BSH activity in faeces, and modifications to the faecal bile acid profile were observed. Additionally, expression levels of TGR5 and TPH1 in the colon of the mice increased, leading to elevated 5-HT levels. When the TGR5 gene was knocked out or the TPH1 inhibitor LX1606 was administered to suppress 5-HT synthesis in constipated mice, the beneficial effects of Li05 on gastrointestinal motility and mucus secretion were reversed. Culturing intestinal organoids demonstrated that increased bile acids such as DCA, Iso-LCA, and EALCA could enhance 5-HT levels through the TGR5/TPH1 axis. Therefore, we concluded that Li05 regulated bile acid metabolism, subsequently increasing 5-HT levels through the TGR5/TPH1 axis, thus alleviating constipation. Graphical The mechanism of Li05 in alleviating constipation. Li05 intervention regulated gut microbiota and bile acid metabolism, increasing 5-HT levels through the TGR5/TPH1 activation to ameliorate constipation.
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DOI
PubMed
高影响因子
JOURNAL OF THE ENERGY INSTITUTE
·
2026
·
IF 6.5
Siwei Yan,Kezhen Qian,Dezhen Chen
The catalytic conversion of plastic waste is often complicated by additives. This study systematically investigates the influence of nonylphenol, a common oxygenated additive, on the catalytic performance of HY (FAU-type) and HZSM-5 (MFI-type) zeolites using high-density polyethylene (HDPE) and n -octane. The research revealed that nonylphenol exhibits a dual role: it provides an initial activity enhancement via bimolecular hydride transfer but more significantly acts as a potent coke precursor, driving rapid deactivation through pore-mouth blockage. Although nonylphenol accelerated deactivation, it did not alter the fundamental cracking pathway of n -octane on either zeolite. There are significant differences in deactivation behavior and selectivity trends between HDPE raw materials and n -octane model compounds. This discrepancy reveals the limitations of using n -octane as models to predict catalyst behavior in polyethylene catalytic cracking.
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产品关联
DOI
高影响因子
JOURNAL OF CLINICAL INVESTIGATION
·
2026
·
IF 14.3
Gengmiao Xiao,Aijun Qian,Zhuo Gao,Tingting Dai,Hui Liang,Shuai Wang,Mulan Deng,Yunjing Yan,Xindan Zhang,Xuedi Zhang,Yunping Mu,Jiqiu Wang,Aibo Gao,Huijie Zhang,Fanghong Li,Allan Zijian Zhao
Aging commonly causes decline of testosterone or estrogen, leading to overaccumulation of fatness in males or females, respectively. Although such phenomenon can be readily explained by estrogen’s direct action on adipocytes in females, accumulative evidence does not support the direct action of testosterone in adipocyte lipid metabolism, suggesting that there is a missing intermediary link. Herein, we propose that glycoprotein hormone β5 (GPHB5) is the intermediary linkage between testosterone and the regulation of adiposity. In clinical samples, blood levels of GPHB5 were correlated negatively with men’s ages, and positively with circulating testosterone. Testosterone directly stimulated the expression of GPHB5 in cultured cells, pharmacological blockade of androgen receptor (AR) functions abrogated such effect. Knockout of AR led to not only development of obesity but also reduction of GPHB5 expression. Genetic ablation of GPHB5 in the males, but not in the females, lowered the browning of white adipose tissue, diminished energy expenditure and caused severe obesity. Importantly, elevated blood testosterone didn’t exert its catabolic actions in GPHB5 null mice, and yet, recombinant GPHB5 protein was able to stimulate energy expenditure and reduce adiposity. Taken together, these results provided the strong proof that GPHB5 is the “missing” intermediary hormone linking testosterone (and aging) and its well-known catabolic effect on adipose tissue.
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产品关联
DOI
PubMed
高影响因子
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