Nature Communications
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2025
·Vol. 16
·期 1
·1-11
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IF 15.7
Chu Juan,Liu Zhaoli,Yu Jie,Wang Heng-Guo,Cui Fengchao,Zhu Guangshan
Two-dimensional conjugated metal organic frameworks (2D c-MOFs) hold significant promise as electrode materials for alkali metal ion batteries while their electrochemical properties still lack reasonable and effective regulation. Here, two representative 2D c-MOFs (M-HHTQ/M-HHTP, M=Cu or Ni) as positive electrodes are used as models to explore the basic/microscopic principles of their complex storage mechanism in sodium ion batteries (SIBs). It is demonstrated that the energy storage mechanism of 2D c-MOFs is determined by the interaction between coordination covalent bonds and organic linkers. Theoretical calculations and experiment results have jointly demonstrated that the redox potential and theoretical capacity can be regulated based on the valence of M-O bond and the utilization of anions and cations, respectively. As a result, Cu-HHTQ achieves a high discharge voltage at 2.55 V (vs. Na + /Na), a higher stable specific capacity of 208 mAh g −1 at 0.05 A g −1 , and long cyclability with the capacity retention rate of 100% at 1 A g −1 after 2000 cycles.
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CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Yan Liu,Ling Zhang,Kaiyang Guo,Jingyuan Zhao,Yonglei Xing,Zhuosen Wang,Yapeng Tian,Xinwei Cui
Intercalation pseudocapacitance is the key point to achieving the balance between the volumetric capacitance and the rate performance of energy storage. However, the low pseudocapacitive reactivity of the active center still limits the energy density of the pseudocapacitance devices. Herein, we propose a strategy that regulates the p - d hybridization of confined MXene via the co-doping of B and O atoms (BO-MXene) for outstanding electrochemical performance. Both experiments and density functional theory (DFT) reveal that the inner doped O atoms in low 2 p orbital energy strengthen the hybridization of Ti and electron-deficient B in MXene for high retention of B atoms, weaken the Ti-O covalency in MXene. As a result, the weakened p - d hybridization of Ti and O for the outer surface and strengthened p - d hybridization of Ti and B for the inner, promote the adsorption of protons and electron transfer, respectively. Further, the BO-MXene-based hybrid supercapacitors achieve a significant volumetric energy density of 56.86 Wh L -1 at 25.6 kW L -1 . This electronic structure via tuning the p - d hybridization in MXene proposes a new path for designing proton-confined intercalation pseudocapacitance.
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ACS Sustainable Chemistry & Engineering
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2025
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IF 7.3
Ranran Wei,Xiaoying Zhang,Min Yan,Yaxuan Li,Ruichen Geng,Zekai Shen,Yinglong Wang,Shuli Yin
Ammonia (NH3), the second most produced chemical in the world, is predominantly utilized in fertilizer production to underpin modern agriculture and has recently attracted interest as an energy-dense source of renewable energy. Herein, an amorphous CuTe porous nanonets (CuTe PNs) catalyst with p-d orbital hybridization was designed and prepared for NH3 synthesis via the nitrite reduction reaction. The porous and amorphous structure of CuTe PNs provides sufficient channels for molecular penetration and enhances active site accessibility through its abundant defects and vacancies, facilitating electrochemical reactions. The CuTe PNs exhibit excellent nitrite reduction reaction performance (NH3 yield: 633.7 μg h–1 mgcat–1, Faradaic efficiency: 91.41%, NH3 selectivity: 92.2%). This work describes a powerful pathway for the fabrication of p-d orbital hybrid amorphous porous nanonets catalysts and also provides a new possibility for the electrochemical synthesis of NH3.
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Plant Methods
·
2019
·Vol. 15
·期 1
·1-13
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IF 3.17
Song Yadi,Chen Shang,Wang Xiujuan,Zhang Rui,Tu Lichan,Hu Tianyuan,Liu Xihong,Zhang Yifeng,Huang Luqi,Gao Wei
Background Tripterygium wilfordii Hook. f. ( T. wilfordii ) is an important medicinal plant with anti-inflammatory, immunosuppressive and anti-tumor activities. The main bioactive ingredients are diterpenoids and triterpenoids, such as triptolide, triptophenolide and celastrol. However, the production of terpenoids from original plants, hairy roots and dedifferentiated cells (DDCs) are not satisfactory for clinical applications. To find a new way to further improve the production of terpenoids, we established a new culture system of cambial meristematic cells (CMCs) with stem cell-like properties, which had strong vigor and high efficiency to produce large amounts of terpenoids of T. wilfordii . Results CMCs of T. wilfordii were isolated and cultured for the first time. CMCs were characterized consistent with stem cell identities based on their physiological and molecular analysis, including morphology of CMCs, hypersensitivity to zeocin, thin cell wall and orthogonal partial least square-discriminant analysis, combination of transcriptional data analysis. After induction with methyl jasmonate (MJ), the maximal production of triptolide, celastrol and triptophenolide in CMCs was 312%, 400% and 327% higher than that of control group, respectively. As for medium, MJ-induced CMCs secreted 231% triptolide and 130% triptophenolide at the maximum level into medium higher than that of control group. Maximal celastrol production of induced CMCs medium was 48% lower than that of control group. Long-term induction significantly enhanced the production of terpenoids both in cells and medium. The reason for increasing the yield of terpenoids was that expression levels of 1 - deoxy - d - xylulose - 5 - phosphate synthase ( DXS ), 1 - deoxy - d - xylulose - 5 - phosphate reductoisomerase ( DXR ) and hydroxymethylglutaryl - CoA synthase ( HMGS ) were upregulated in CMCs after induction. Conclusions For the first time, CMCs of T. wilfordii were isolated, cultured, characterized and applied. Considering the significant enrichment of terpenoids in CMCs of T. wilfordii , CMCs could provide an efficient and controllable platform for sustainable production of terpenoids, which can be a better choice than DDCs.
研究领域:
植物生物技术
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植物化学
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药用植物
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SEPARATION AND PURIFICATION TECHNOLOGY
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2025
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IF 9
Derui Zheng,Yu Wang,Jianhua Zu,Siyu Liu
This study developed a novel defective composite material (UiO-66/D-AMP) based on defect engineering and in situ synthesis of ammonium phosphomolybdate (AMP) for the highly selective capture of Cs + and Sr 2+ . The changes in adsorption capacity and surface functional groups of the composite before and after defect engineering were analyzed by adsorption experiment and FT-IR characterization. It was found that the defect-engineered composite had obvious carboxyl groups, and the adsorption efficiency of Sr 2+ was effectively improved. Several analytical methods were employed to verify the effective incorporation of AMP onto the UiO-66 framework. SEM-EDS was utilized to examine surface morphology and elemental composition. FTIR confirmed the presence of functional groups, while XRD analysis validated the crystalline structure. Additionally, TG assessed thermal stability, and BET measurements determined the material's surface area and porosity, collectively confirming AMP loading. The UiO-66/D-AMP composite exhibited significant adsorption affinity for both Cs + and Sr 2+ ions, demonstrating its potential for radioactive wastewater treatment. Under alkaline conditions (pH 10), the composite demonstrated exceptional removal efficiencies of 98.43% for Cs + and 99.54% for Sr 2+ . The maximum adsorption capacities were determined to be 104.3 mg/g for Cs + and 20.18 mg/g for Sr 2+ . Notably, the adsorption kinetics revealed rapid equilibration times of 5 min for Cs + and 60 min for Sr 2+ . The adsorption kinetics of Cs + and Sr 2+ followed the pseudo-second-order model, while the adsorption isotherms fitted well with the Langmuir model. In mixed solutions containing Cs + , Sr 2+ , and four competing ions, UiO-66/D-AMP exhibited excellent selectivity for both Cs + and Sr 2+ . Remarkably, the adsorption capacities for Cs + and Sr 2+ remained stable following exposure to various adsorbed doses. XPS provided direct evidence for the ion exchange mechanism between Cs + and NH 4 + during adsorption. Sr 2+ first exchanged with H + on UiO-66/D-AMP, then coordinated with the oxygen atom in the carboxyl group to be adsorbed.
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Advanced Healthcare Materials
·
2025
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IF 9.6
Wenhui Hu,Zhicheng Cao,Mengtao Wang,Zhiwen Dong,Yufeng Wang,Xin Zhang,Yan Xu,Liming Wang,Changyan Ma,Cheng Tang
Endogenous regenerative strategy for osteochondral defect (OCD) repair remains challenging, largely due to the need to regulate the local inflammatory and metabolic microenvironment while preserving the stemness of bone marrow mesenchymal stem cells (BMSCs). Here, D-mannose we identify as a potent immunometabolic modulator that enhances BMSC-mediated osteochondral repair. Through in vitro experiments, we determined the optimal concentration of D-mannose and evaluated its ability to preserve the osteogenic and chondrogenic differentiation potential of BMSCs under inflammatory microenvironment. Transcriptomic analysis demonstrated that D-mannose contributed to the amelioration of inflammation by downregulating the NLRP3 inflammasome pathway. The metabolomic analysis further revealed that D-mannose treatment alleviated inflammation-induced dysregulation of the tricarboxylic acid cycle and facilitated the maintenance of glycolytic metabolic state in BMSCs. Furthermore, we fabricated a multifunctional GelMA-based hydrogel incorporating D-mannose (DM@GelMA). Macroscopic observation, micro-CT analysis and histological evaluation confirmed that DM@GelMA hydrogel effectively promoted osteochondral tissue remodeling and integration in the OCD model of rats. These findings suggested that the multifunctional D-mannose-loaded composite hydrogel is a promising biomaterial for enhanced osteochondral regeneration.
研究领域:
生物医学工程
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再生医学
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免疫代谢
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组织工程
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生物材料
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Nano Today
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2025
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IF 10.9
Wei Hu,Jiaxi Xu,Mingchen Lv,Min Sun,Zhen Fan,Jianzhong Du
Immunotherapy offers enduring cancer treatment by activating the immune system to eliminate cancer cells, but faces challenges like tumor immune evasion and low immunogenicity. Chirality, crucial in biological interactions, remains underexplored for immune modulation. Inspired by the metal-binding domain of manganese superoxide dismutase, we develop a cyclic D/L peptide for chirality-driven immune activation. The cyclic L -Tyr- D -His- L -Asp- D -His (YhDh) peptide coordinates with Mn 2+ to self-assemble into nanoparticles, cloak with tumor cell membranes for homologous targeting. Compared to all-L or all-D peptides, YhDh nanoparticles promote costimulatory molecule expression on dendritic cells (DCs). Upon intravenous administration, they are oxidized at melanoma sites with tyrosinase overexpression, enabling photothermal-induced immunogenic cell death (ICD). Chiral peptides synergize with Mn 2+ -mediated cGAS-STING activation and ICD, enhancing DC maturation and T cell infiltration (4.36- and 2.88-fold), suppressing tumor metastasis while establishing immune memory. Such chiral cyclic peptides offer a novel strategy for immune activation by regulating peptide chirality.
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Journal of Materials Chemistry C
·
2019
·Vol. 7
·期 33
·10379-10388
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IF 6.641
Tao Hua,Keyi Zhang,Zu-Sheng Huang,Lingyun Wang,Hao Tang,Herbert Meier,Derong Cao
In this paper, the encapsulated insulated molecular wire (EIMW) and 2′,7′-bis(hexyloxy)spiro[cyclopenta[2,1-b:3,4-b′]dithiophene-4,9′-fluorene] (SPDF) were specifically designed as efficient anti-aggregation π-bridges for two novel D–A–π–A metal-free sensitizers (IBT1 and IBT2). Compared with the reference dye IBT3 with 3,3′-dihexyl-2,2′-bithiophene (DHBT) as an anti-aggregation π-bridge, both the dyes IBT1 with EIMW and IBT2 with SPDF as π-bridges can suppress intermolecular aggregation more efficiently. The π-bridge of SPDF shows the strongest anti-aggregation ability due to the rigid ‘T’ configuration among these dyes. Meanwhile, the π-bridge of EIMW shows better anti-aggregation ability than DHBT because of the larger steric hindrance of the former. Finally, when the dyes IBT1 and IBT2 are co-sensitized with IBT3, respectively, the new devices exhibit high efficiencies of 7.85% and 7.64%, respectively, which are comparable to that of N719 (7.85%). The results demonstrate that the dyes with EIMW and SPDF as anti-aggregation π-bridges are promising candidates for efficient DSSCs and dye aggregation can be effectively inhibited by structural engineering of the π-spacer.
研究领域:
材料科学
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化学工程
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DYES AND PIGMENTS
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2023
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IF 4.5
Peiyu Wu,Shengxiong Zhang,Wenjun Zhang,Weijie Song
Dual functional electrochromic (EC)/electrofluorochromic (EFC) materials play a pivotal role in wearable and smart electronic equipments. Developing new materials with high performance of EC/EFC properties is still a big challenge. Here a new D-A structure polymer PPDOTTPD based on thieno(3,4-c)pyrrole-(4,6)dione ( TPD ) was synthesized by Stille coupling, and the EC/EFC properties were investigated for the first time. PPDOTTPD film exhibits reversible color changes from purple neutral state to transparent colored state in the process of reversible redox. Photophysical and electrochemical studies revealed that the polymer has outstanding EC properties, including high optical contrast (52%), fast response time (0.5 s/0.7 s), high coloring efficiency (427.1 cm 2 C −1 ) and good stability. What's more, PPDOTTPD exhibited EFC phenomenon. PPDOTTPD film showed an intense red near-infrared fluorescence with a peak of 672 nm, which gradually doped with the increase of applied potential with a maximum contrast ratio of 12.9. The EC/EFC dual-functional device based on PPDOTTPD was also successfully fabricated, which exhibited high optical and fluorescence contrast. The fine dual-functional performance indicates TPD can be further explored as potential acceptors for synthesizing high performance D-A molecules for intelligent optical devices.
研究领域:
材料科学
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电子工程
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ACS Sensors
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2025
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IF 9.1
Changle Pei,Muhammad Hamza Nadeem,Nan Li,Jun Fu,Nan Xu,You Wang,Adrian Carl Stevenson,Guang Li,Ruifen Hu
The complexity of in situ volatile organic compounds (VOCs) detection demands high selectivity and anti-interference capability of electronic noses (E-noses). Multivariant virtual sensor array (VSA) is a new generation of E-noses under research to overcome the insufficient VOCs selectivity limitation of existing electronic noses and alleviate the issue of sensor drifts. In this paper, a frequency-amplitude dual-parameter modulation strategy is presented on a wireless electrodeless quartz crystal microbalance with dissipation (WE-QCM-D) to realize the recognition and analysis of VOC mixtures and complex real-world analytes with a single multivariant VSA E-nose, by probing the gas dynamic sorption in a sensitive film at various scales of oscillating shear displacements and obtaining multiple partially independent responses to VOCs. Ten VOC analytes from alcohols, esters, and aromatic hydrocarbons were classified with accuracies of above 95% for both interclass and intraclass discriminations. Additionally, a discriminating accuracy of 95% has been achieved on VOC mixtures, and their component concentrations were predicted with coefficients of determination above 0.9. For practical testing, the system was exposed to the headspace VOCs of banana, pineapple, and mango under different concentrations. It recognized different fruits and identified the ripen state of bananas based on the detection of their volatiles. The dual-parameter modulated WE-QCM-D paves a promising multivariant way to realize online real-time VOCs monitoring with high performance on selectivity and quantitative analysis.
研究领域:
传感器与传感系统
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环境监测
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分析化学
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电子鼻
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气体检测
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Nano Energy
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2020
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IF 16.602
Zheng Zhou,Xiangxin Du,Zhao Zhang,Jikui Luo,Shaoyu Niu,Da Shen,Yuanyu Wang,Hui Yang,Qilong Zhang,Shurong Dong
Flexible piezoelectric nanogenerator (PENG) has been regarded as one of the promising solutions to harvesting mechanical energy, as a sustainable energy source for wearable devices , etc. Here, a universal strategy of carbon coating modulation is proposed to synthesis carbon coated 0-D piezoceramics nanoparticles (NPs). Owing to the good electric conductivity of carbon shell, the redistribution and accumulation of mobile charges in carbon layer gives rise to reinforcement of electric field, results in the much-enhanced piezoelectric effect. Polydimethylsiloxane (PDMS) composites with those 0-D piezoceramics NPs are used to fabricate PENGs. The peak power density of BT@C, PZT@C and KNN@C based PENGs reaches up to 45.4 μW/cm 2 , 59.8 μW/cm 2 and 9.9 μW/cm 2 , that are 20, 20.4 and 13.4 times larger than those of control PENGs incorporated with bare 0-D piezoceramic NPs, respectively. A theoretical model based on Lewis diffusion theory is constructed to reveal the mechanism of piezoelectric enhancement in the poling process. This research provides a new strategy for synthesis of high piezoelectric characteristic composites by embedding carbon coated 0-D piezoceramic NPs.
研究领域:
材料科学
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能源技术
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JOURNAL OF COORDINATION CHEMISTRY
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2020
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IF 1.41
Kun Lu,Zihan Zhu,Lin Peng,Hai Fu,Xinlong Wang,Enbo Wang
An unusual metal-organic framework, {H[Ag(I)L][Mo(VI)4O13]}n (1) (L=(4-((1H-1,2,4-triazol-1-yl)methyl)phenyl)methanol)), has been obtained under ionothermal conditions. According to the single-crystal X-ray diffraction analysis, 1 is a new 3-D framework based on β-[Mo8O26]4− type polymolybdate anions with two kinds of channels (A and B) along the b-axes and c-axes in the framework. The neighboring inorganic Mo8-Ag chains are linked by the organic ligands through the Ag centers resulting in 2-D layers. These adjacent 2-D layers extend into a 3-D framework through Ag1 nodes and β-[Mo8O26]4− anions, respectively, resulting in a topological symbol (64 · 82)2(64 · 82). In addition, the gas adsorption, proton conduction and luminescent properties of 1 are also discussed in detail. Moreover, the electrochemical impedance spectroscopy (EIS) measurements show a conductivity (1.9 × 10−4 S cm−1 at 65 °C and 95% relative humidity (RH)), with an activation energy of 0.41 eV for 1. The mechanism of proton conduction for 1 is proved to be the vehicular mechanism.
研究领域:
材料科学
·
化学
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危险品化学品经营许可证（带存储）