MOLECULES
·
2023
·Vol. 28
·期 14
·5304
·
IF 4.6
Caiyuan Liu,Xin Fang,Hui Peng,Yi Li,Yonggang Yang
The aim of this work is to effectively combine the advantages of polymer and ceramic nanoparticles and improve the comprehensive performance of lithium-ion batteries (LIBs) diaphragm. A flexible film composed of electro-spun P(VDF-HFP) nanofibers covered by a layer of mesoporous silica (P(VDF-HFP)@SiO2) was synthesized via a sol–gel transcription method, then used as a scaffold to absorb organic electrolyte to make gel a electrolyte membrane (P(VDF-HFP)@SiO2-GE) for LIBs. The P(VDF-HFP)@SiO2-GE presents high electrolyte uptake (~1000 wt%), thermal stability (up to ~350 °C), ionic conductivity (~2.6 mS cm−1at room temperature), and excellent compatibility with an active Li metal anode. Meanwhile, F-doping carbon/silica composite nanofibers (F-C@SiO2) were also produced by carbonizing the P(VDF-HFP)@SiO2film under Ar and used to make an electrode. The assembled F-C@SiO2|P(VDF-HFP)@SiO2-GE|Li half-cell showed long-cycle stability and a higher discharge specific capacity (340 mAh g−1) than F-C@SiO2|Celgard 2325|Li half-cell (175 mAh g−1) at a current density of 0.2 A g−1after 300 cycles, indicating a new way for designing and fabricating safer high-performance LIBs.Keywords:composite materials;electro-spun nanofiber;gel electrolyte;carbonaceous anode;lithium-ion batteries
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JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
·
2023
·
IF 4.9
Yuying Bai,Dawei Tian,Zhengxin Ren,Dangyang Yue,Qian Ren,Li Pei,Jun Pan
Though magnetic iron oxide nanoparticles (IONPs) are approved for clinical use as contrast agents for MR imaging in United States and Europe, and are widely used to label cells in research, the relationship between IONPs and mesenchymal stem cells (MSCs) is not fully addressed. Here the effects of consistently appeared γ-Fe 2 O 3 on the lineage commitment of MSCs were studied to optimize applications of IONPs in MSCs upon verification of viability. 30 nm 10 μg/mL induced highest promotions on osteogenesis, while 30 and 50 nm of 100 μg/mL elicited most chondrogensis in 14 days, where the effects on ALP, GAG and SOX9 appeared after 7 days, while on RUNX2 came out after 10 days. γ-Fe 2 O 3 enhanced intracellular and extracellular Fe 3+ and ROS, modulated F-actin and decreased Lamin A of MSCs at different time scale. The disturbances of F-actin, Lamin A or ROS altered the effects of γ-Fe 2 O 3 on MSC differentiation. Our results demonstrate that different size, concentration and modulation of γ-Fe 2 O 3 are needed in its MSC applications for bone and cartilage tissues. Furthermore, an undocumented phenomenon that the modulation of F-actin affected the Lamin A expression in MSCs was observed.
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HIGH PERFORMANCE POLYMERS
·
2019
·
IF 1.584
Yinhong Liu,Yuhan Wei,Yongshuang Bian,Shengjiao He,Xin Wang,Xin Liu,Chenglei Li,Qi Wu,Xianyin Zeng,Hanguang Wang,Kuan Liu
Design and synthesis of highly selective fluorine ion probes become particularly important owing to the specific role of fluorine ion in chemical and biomedical progresses. As a new-type of fluorescent material, conjugated polymers with unique photometric properties have been widely researched by scientists in the field of the fluorescence sensors. In this study, the polymer PBTPV-OSi containing benzothiazole moiety is synthesized via palladium-catalyzed Heck coupling reaction. This polymer not only exhibits good solubility in organic solvents but also shows high selectivity for fluorine ion detection in comparison to other anions. Upon addition of F− to PBTPV-OSi solution, Si–O cleavage of PBTPV-OSi leads to the fluorescence quenching of the polymer in tetrahydrofuran dramatically, and the detection limit is 8 × 10−6 mol/L. Moreover, besides detecting fluorine ion from organic phase, the probe can also effectively detect potassium fluoride from inorganic phase. More importantly, a naked-eye detectable chromogenic and fluorogenic dual response to fluorine ion (F−) can be visibly noted and the detection process of fluorine ion is relatively fast.
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JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2024
·
IF 3.5
Xiaohui Wu,Xixi Wang,Yulan Jing,Yuanxun Li,Hua Su
With the emergence of 5G–6G communication technology, the miniaturization and integration of electronic components are crucial. Ba 3 Ti 4 Nb 4 O 21 (BTN) ceramics with hexagonal structures have attracted special attention due to their high dielectric constant, which shows greater application potential in communication base stations and dielectric resonators. However, its high sintering temperature and low-quality factors also greatly limit the application field. In this paper, boric acid (H 3 BO 3 ) as a dopant, was used to investigate the influence on the structure, microstructure, Raman spectrum, and microwave properties for Ba 2.92 Cu 0.08 (Zn 1/3 Nb 2/3 ) 2 Ti 2 Nb 4 O 21 (BCZTN)- x HB (0.25≤ x ≤1.25 wt%) ceramics. The results reflected that H 3 BO 3 was an effective additive, which could promote ceramic densification, accelerate grain growth and uniform distribution, and enhance its microwave performance. Among them, high densification was 93.92 ± 0.35%, and the Q × f value ∼16981 ± 340 GHz at x = 0.75, was more than 2∼3 times higher than other BTN-based ceramics. Superior microwave dielectric properties were achieved for 0.75 wt% H 3 BO 3 -doped BCZTN ceramic sintered at 900°C: ε r ∼42.35 ± 0.48, Q× f ∼16981 ± 340 GHz, and τ f ∼40.02 ± 1.43 ppm/°C. More encouragingly, BCZTN-0.75HB ceramic did not chemically react with Ag, which suggested that it had the potential to be a candidate material for low-temperature co-fired ceramics base station communication devices.
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Journal of Materials Chemistry B
·
2021
·Vol. 9
·期 44
·9204-9212
·
IF 6.331
Xinyue Guo,Zongjia Li,Sitong Liu,Miaomiao Zhang,Yanxue Guan,Juan Qin,Xiaomeng Li,Bailin Zhang,Jilin Tang
Studying the influence of nanomaterials on the microstructure and mechanical properties of cells is essential to guide the biological applications of nanomaterials. In this article, the effects of the first synthesized PDA@CeO2 nanoparticles (NPs) with multiple ROS scavenging activities on cell ultra-morphology and mechanical properties were investigated by atomic force microscopy (AFM). After the cells were exposed to PDA@CeO2 NPs, there was no obvious change in cell morphology, but the Young's modulus of the cells was increased. On the contrary, after the cells were damaged by H2O2, the secreted molecules appeared on the cell surface, and the Young's modulus was decreased significantly. However, PDA@CeO2 NPs could effectively inhibit the reduction of the Young's modulus caused by oxidative stress damage. PDA@CeO2 NPs could also protect F-actin from oxidative stress damage and maintain the stability of the cytoskeleton. This work investigates the intracellular antioxidant mechanism of nanomaterials from the changes in the microstructure and biomechanics of living cells, providing a new analytical approach to explore the biological effects of nanomaterials.
研究领域:
纳米技术
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生物物理学
·
细胞生物学
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材料科学
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Advanced Healthcare Materials
·
2023
·
IF 10
Bijun Zhu,Jiangjiexing Wu,Tong Li,Songtao Liu,Junheng Guo,Yijun Yu,Xinyi Qiu,Yue Zhao,Haoran Peng,Jinli Zhang,Leiying Miao,Hui Wei
The use of oxidoreductase nanozymes to regulate reactive oxygen species (ROS) has gradually emerged in periodontology treatments. However, current nanozymes for treating periodontitis eliminate ROS extensively and non-specifically, ignoring the physiological functions of ROS under normal conditions, which may result in uncontrolled side effects. Herein, using the MIL-47(V)-F (MVF) nanozyme, which mimics the function of glutathione peroxidase (GPx), we propose that ROS can be properly regulated by specifically eliminating H 2 O 2 , the most prominent ROS. Through H 2 O 2 elimination, MVF contributes to limiting inflammation, regulating immune microenvironment, and promoting periodontal regeneration. Moreover, MVF stimulates osteogenic differentiation of periodontal stem cells directly, further promoting regeneration due to the vanadium in MVF. Mechanistically, MVF regulates ROS by activating the Nrf2/HO-1 pathway and promotes osteogenic differentiation directly through the PI3K/Akt pathway. We present a promising periodontitis therapy strategy using GPx-mimicking nanozymes through their triple effects of antioxidation, immunomodulation, and bone remodeling regulation, making nanozymes an excellent tool for developing precision medicine. This article is protected by copyright. All rights reserved
研究领域:
牙科学
·
纳米技术
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再生医学
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免疫学
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生物化学
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JOURNAL OF PHYSICS D-APPLIED PHYSICS
·
2023
·Vol. 57
·期 1
·015301
·
IF 3.4
Xiao Zhang,Zhe Xiong,Bin Tang,Chengtao Yang
The rapid advancement of mobile communications technology is imposing greater demands on electronic components. Microwave dielectric ceramics with a high dielectric constant (r) are crucial for the miniaturization and integration of microwave devices. Herein, The perovskite-structured (Ca0.61Nd0.26)1−x(Li0.5Nd0.5)xTiO3 (0 ⩽ x ⩽ 0.8) microwave dielectric ceramics with high r value were prepared by solid-state reaction method. The results demonstrated that the r value reached its peak at x = 0.6, which was influenced by the bond valence at B-sites. The τf and Q× f values decreased with increasing x value. Doping (Li0.5Nd0.5)2+ at A-sites led to an increase in the full width at half maximum of Raman peaks, indicating higher internal loss. A high dielectric constant and temperature-stable (Ca0.61Nd0.26)0.27(Li0.5Nd0.5)0.73TiO3 ceramic can be sintered with good microwave dielectric properties of r = 129.4, Q× f= 2,787 GHz, and τf = +1.9 ppm/°C.
研究领域:
材料科学
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电气工程
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微波技术
·
陶瓷
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Materials Chemistry Frontiers
·
2022
·Vol. 6
·期 10
·1292-1300
·
IF 8.683
Yueyue He,Zhuo Chen,Xiaogang Chen,Xian-Ming Zhang,Dongying Fu
Organic–inorganic hybrid perovskite (OIHP) multifunctional molecular switching materials have been widely studied as excellent supplements to the conventional all-inorganic perovskites due to their structural diversity and property adjustability. However, considering their practical application, the phase transition temperature (Tp) of the system is a crucial evaluation standard and meanwhile it remains an arduous challenge to construct phase transition materials with three kinds of switching characteristics. Therefore, the design of high Tp multifunctional switching materials is a huge task. Herein, we have reported a chiral OIHP multifunctional semiconductor 2 ([(R)-N-fluoroethyl-3-quinuclidinol]PbBr3) with dielectric switching, nonlinear switching and ferroelastic switching characteristics and an ultrahigh Tp of 498 K, which is obtained from compound 1 ([(R)-N-ethyl-3-quinuclidinol]PbBr3) with a Tp of 445 K through the strategy of H/F substitution. The substitution of F atoms for H atoms not only changes the coordination environment of Pb, but also increases the molecular interactions due to the stronger electronegativity of the F atoms, which raises the barrier of rotation of the fluorinated organic cations, (R)-N-fluoroethyl-3-quinuclidinol, and finally leads to a remarkable increase in Tp. Ultimately, through accurate molecular design, the Tp of compound 2 has been increased by 53 K and compound 2 exhibits three kinds of switching characteristics, which also makes it a superior switching material for practical application.
研究领域:
材料科学
·
化学
·
物理学
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Frontiers in Chemistry
·
2021
·
IF 5.221
Wu Panpan,Tang Xiaowen,Jian Rongchao,Li Jiahao,Lin Maoyu,Dai Huachao,Wang Kangpeng,Sheng Zhaojun,Chen Baizhong,Xu Xuetao,Li Chen,Lin Zhongze,Zhang Qingmin,Zheng Xi,Zhang Kun,Li Dongli,Hong Weiqian David
Two essential oils were isolated from discarded perfume lemon and leaves (Citrus limon (L.) Burm. F.) by hydro-distillation with good yield (0.044% for perfume lemon and 0.338% for leaves). Their biological activities were evaluated against five selected bacterial strains and Aedes albopictus (Ae. albopictus, Diptera: Culicidae). Chemical composition indicated that both essential oils were rich in essential phytochemicals including hydrocarbons, monoterpenes and sesquiterpene. These constituents revealed some variability among the oils displaying interesting chemotypes (R)-(+)-limonene (12.29–49.63%), citronellal (5.37–78.70%) and citronellol (2.98–7.18%). The biological assessments proved that the two essential oils had similar effect against bacterial (inhibition zones diameter ranging from 7.27 ± 0.06 to 10.37 ± 0.15 mm; MICs and MBCs ranging from 1.6 to 6.4 mg/mL); against Ae. albopictus larvae (LC50 ranging from 384.81 to 395.09 ppm) and adult mosquito (LD50 ranging from 133.059 to 218.962 μg/cm2); the activity of the two chemotypes ((R)-(+)-limonene and citronellal): larvae (LC50 ranging from 267.08 to 295.28 ppm), which were all presented in dose-dependent manners. Through this work, we have showcased that recycling and reusing of agriculture by-products, such as discarded perfume lemon and leaves can produce eco-friendly alternatives in bacterial disinfectants and mosquito control product.
研究领域:
植物化学
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生物活性研究
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农业废弃物利用
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Yuhang Hu,Xuhui Kan,Tingting Yang,Xia Fan,Wangting Zhou,Guijie Chen,Yamei Yan,Lu Lu,Jia Mi,Xiaoxiong Zeng,Youlong Cao
Chlorogenic acids are important phenolics in the fruits of wolfberry, but little attention has been paid on their glucosylated forms. In the present study, a glucosylated form of chlorogenic acid was isolated from the fruits of Lycium barbarum L. var. auranticarpum K. F. Ching (also called yellow wolfberry) and identified to be (-)-5- O -(3- O -β- d -glucopyranosylcaffeoyl)-quinic acid (5-CQA-3′βG) by high resolution mass spectrometry and nuclear magnetic resonance spectrometry. The content of 5-CQA-3′βG in the dried fruit was determined as 0.0293 ± 0.0015% by HPLC. In addition, 5-CQA-3′βG showed a good scavenging capacity for 2,2′-azino-bis-(3-ethylben-zothiazoline-6-sulphonate) free radicals but had a relatively low reducing power and scavenging capacity for 2,2-diphenyl-1-picrylhydrazyl free radical. Moreover, the secretion of nitric oxide, tumor necrosis factor-α and interleukin-6 as well as related mRNA expression were reduced in lipopolysaccharide-stimulated RAW264.7 macrophage cells treated with 5-CQA-3′βG. This is the first report describing purification, identification and bioactivity of glucosylated CQA from yellow wolfberry.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Zhikun Wang,Zhihua Zhao,Chen Chen,Guixin Jin,Xiaoqing Shen,Zhigang Shao,Lan Wu
Environmental safety monitoring has significantly benefited from the incorporation of gas sensors. Given the pernicious effects of ammonia and acetic acid gases on the environment and human health, it is imperative to develop a room temperature dual-functional gas sensor capable of simultaneously detecting both these gases. In this research endeavor, acid-functionalized multi-walled carbon nanotubes (f-MWCNTs) were integrated with Bi 2 S 3 through a hydrothermal approach, leading to the fabrication of a Bi 2 S 3 /f-MWCNTs-2 nanocomposite-based chemoresistive gas sensor. The results demonstrate that the Bi 2 S 3 /f-MWCNTs-2 sensor exhibits a response value of 52.7 % towards 100 ppm NH 3 at room temperature (25℃), displaying a declining resistance curve upon exposure to the target gas. Similarly, for 100 ppm CH 3 COOH under ambient conditions (25℃), the sensor records a response value of 72.55 %, accompanied by a rising resistance curve when in contact with CH 3 COOH gas. The distinctive feature of this dual-functional sensor lies in its ability to detect opposing transient response curves for the two gases, which is crucial for distinguishing between different gases. Furthermore, the sensor boasts swift response recovery, excellent repeatability, and robust stability. This study underscores the promising potential of the Bi 2 S 3 /f-MWCNTs-2 nanocomposite sensor in applications such as environmental monitoring.
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JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2024
·
IF 3.3
Xiefei Li,Yupeng Lin,Yumeng Huang,Xin Li,Fengping An,Hongbo Song,Qun Huang
BACKGROUND Pectin extracted by high-speed shearing from passion fruit peel (HSSP) is a potentially excellent wall material for encapsulating curcumin, which has multiple advantages over pectin prepared by heated water extraction. HSSP was used to fabricate complex nanoparticles of zein–sodium caseinate–pectin for encapsulation of curcumin in this study. The influence of heating on the physicochemical properties of the composite nanoparticles was also investigated, as well as the effect of composite nanoparticles on the encapsulation efficiency, antioxidant activity and release characteristics of curcumin. RESULTS The nanoparticles were formed through electrostatic interactions, hydrogen bonds and hydrophobic interactions between the proteins and HSSP. A temperature of 50 °C was more favorable for generating compact and small-sized nanoparticles, which could effectively improve the encapsulation efficiency and functional properties. Moreover, compared to other pectin used in the study, the nanoparticles prepared with HSSP showed the best functionality with a particle size of 234.28 ± 0.85 nm, encapsulation rate of 90.22 ± 0.54%, free radical scavenging rate of 78.97% and strongest protective capacity in simulated gastric fluid and intestinal release effect. CONCLUSION Zein–sodium caseinate–HSSP is effective for encapsulating and delivering hydrophobic bioactive substances such as curcumin, which has potential applications in the functional food and pharmaceutical industries. © 2024 Society of Chemical Industry.
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危险品化学品经营许可证（带存储）