Scientific Reports
·
2025
·Vol. 15
·期 1
·1-13
·
IF 3.9
Xiong Wei,Zhou Yuxiang,Li Yuyi,Yuan Yifeng,Liu Kang,Huang Xudong,Li Jingkun,Zhang Zechen,Shi Xiaolin,Li Miao’er
Infectious bone defect is a condition where infection and bone defect occur simultaneously. The simultaneous achievement of effective antimicrobial management and enhanced bone regeneration continues to present a major hurdle in musculoskeletal therapeutics. To address these limitations, we have developed a novel osteoconductive material, this material (PDA@Mg-MOF-LEV) consists of Magnesium-based metal-organic frameworks (Mg-MOF) particles loaded with the antibiotic levofloxacin (LEV) and coated with polydopamine (PDA), which integrates photothermal therapy with antibiotic delivery to combat bacterial drug resistance and facilitate bone tissue regeneration. Under near-infrared (NIR) irradiation, PDA@Mg-MOF-LEV particles demonstrate superior antibacterial efficacy and enhanced osteogenic potential. Drug release studies indicate that NIR irradiation significantly increases LEV release by 337% and Mg ions release by 196% compared to standard conditions. Furthermore, in vitro antibacterial assays confirm that NIR irradiation markedly enhances the antibacterial activity of PDA@Mg-MOF-LEV particles, achieving inhibition rates of 97.5 ± 1.45% against Escherichia coli ( E. coli ) and 98.5 ± 2.27% against Staphylococcus aureus ( S. aureus ). The photothermal therapy mediated by NIR irradiation not only enhances antibacterial efficacy but also directly stimulates osteogenic differentiation and calcium deposition in mBMSCs, positioning PDA@Mg-MOF-LEV as a multi-modal therapeutic platform for infective osteogenesis.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOMACROMOLECULES
·
2025
·
IF 5.4
Chaonan He,Peipei Feng,Dingli Xu,Leidong Lian,Jin Li,Kaifeng Gan,Yi Gu,Tingting Pan,Yun Tang,Xiang Wu,Zhaoxiang Peng,Chunhai Ke,Jingyun Ma
Composite biomaterial systems facilitate regenerative medicine through component synergy. Herein, novel core–shell nanocomposites (N-HMMs) are prepared, with hollow mesoporous silica (HMSNs) as the core and magnesium-gallic acid metal–organic frameworks (Mg-MOFs) as the shell. N-HMMs are loaded with the small-molecule osteoinductive drug naringin (Nar) to form N-HMMs@Nar, which is integrated into methacrylate gelatin/polyethylene glycol diacrylate hydrogels (GelMA/PEGDA, GP) to construct N-HMMs@Nar@GP. N-HMMs@Nar@GP enables sustained release of Nar, bioactive Mg2+, and antioxidant gallic acid for synergistic anti-inflammation, osteogenesis, and angiogenesis of bone regeneration. GP adapts N-HMMs@Nar to the traumatic characteristics of bone defects and facilitates in situ treatments. In vitro studies have confirmed the composite materials’ biocompatibility, osteoinductive differentiation, and angiogenesis capabilities. The ability of N-HMMs@Nar@GP to enhance osteogenesis and angiogenesis is demonstrated in an in vivo tibial defect model using micro-CT and histopathological analysis. Therefore, N-HMMs@Nar@GP holds significant potential for application in the repair of bone defects.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Bojun Zhang,Mingliang Zhang,Sinong Wang,Jinchan Zhao,Zhenyu Dai,Yizhuo Li,Shiliang Mei,Wanlu Zhang,Ruiqian Guo
Paper-based cultural relics possess great historical and cultural value but are vulnerable to irreversible degradation from high-energy ultraviolet (UV) light exposure and acidification, threatening their long-term preservation. Current paper protection predominantly relies on exogenous materials with single functions, which not only provide limited protective effects but also pose a risk of secondary damage. In this study, we developed a Dual-Functional paper by directly integrating a carbon quantum dot–magnesium hydroxide (CQDs@Mg(OH)2) nanocomposite into the papermaking process, thereby endowing the paper with intrinsic resistance to both acidification and UV-induced photodegradation, which reduces the reliance on subsequent protective treatments and fundamentally enhances the paper’s longevity. The results demonstrate that the functional paper integrated with CQDs@Mg(OH)2 nanocomposites shows good structural compatibility and strong resistance to degradation. Under the conditions of both UV exposure and dry-heat aging, the functional paper demonstrates excellent resistance to photooxidative and acid-induced degradation, indicating its strong potential for extending the longevity of paper-based materials. Additionally, the fluorescent properties of CQDs reveal promising potential as optical anticounterfeiting markers. This work opens an avenue for the design of long-lasting functional paper enabled by carbon-based materials, with promising applications in the preservation of paper-based cultural heritage.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materiomics
·
2025
·
IF 9.6
Kui Xue,Min Xing,Tiantian Chen,Bingyun Xi,Haifeng Zhang,Kuicai Ye,Jiayin Feng,Wenhao Qian,Jiajun Qiu,Xuanyong Liu
For alveolar bone defects, magnesium membrane with the mechanical properties of shielding fibrocyte growth and sustainable release of Mg 2+ is an excellent choice for guide bone regeneration (GBR) surgery. However, insufficient osteogenesis and bacterial infection have hindered its application. In this study, Mg-Ga-LDH coating was successfully prepared, which delayed the degradation rate of the Mg membranes and greatly reduced the amount of hydrogen evolution. A weakly alkaline microenvironment (pH =8.5) containing appropriate concentrations of Mg 2+ and Ga 3+ was successfully constructed, effectively promoting the adhesion and proliferation of MC3T3-E1 cells. It also upregulated the expression of alkaline phosphatase and collagen, which were conducive to the formation of mineralized nodules, and promoted the osteogenic differentiation of rat bone marrow mesenchymal stem cells in vitro . In addition, Ga 3+ released from the coating and the generated alkaline microenvironment showed good antibacterial properties against S. aureus . The Mg-Ga-LDH coating can effectively reduce the degradation rate of Mg membranes and mitigate inflammation. The Mg-Ga-LDH coating modified Mg membrane promoted new bone formation in cranial defect animal models. This bone-promoting Mg 2+ and Ga 3+ releasing platform and weak alkaline microenvironment creation system paves the way for the application of Mg membranes in the field of GBR.
✓ 已验证
产品关联
DOI
高影响因子
SURFACE AND INTERFACE ANALYSIS
·
2025
·Vol. 58
·期 1
·35-53
·
IF 1.8
Anda Yu,Yulai Song,Nan Wang,Yong Tian,Hao Chen
Based on the evaluation of sustained-release performance in aqueous solution, sodium dodecyl sulfate (SDS) and phosphate ions were selected as two anionic corrosion inhibitors with excellent inhibition properties. Using hydrothermal treatment, co-precipitation, and anion exchange techniques, LDH-P + S coatings containing both SDS and phosphate and MgAl-LDH coatings intercalated with silicate, phosphate, and SDS were successfully fabricated. The microstructure and composition of the various LDH coatings were characterized using XRD, FT-IR, XPS, SEM, and EDS. The corrosion resistance and durability of the LDH coatings were assessed using EIS, PDP, and hydrogen evolution tests. All four LDH coatings demonstrated good corrosion protection, with the LDH-P + S coating exhibiting slightly superior corrosion resistance compared with the others. Single-frequency EIS analysis was conducted to evaluate self-healing properties, indicating that the LDH-P + S coating performed the best in restoring protection. The superior self-healing behavior is primarily ascribed to the combined contribution of phosphate-induced passivation and SDS-mediated adsorption barrier formation.
✓ 已验证
产品关联
DOI
高影响因子
Materials Science and Engineering B-Advanced Functional Solid-State Materials
·
2025
·
IF 4.6
Haoyue Deng,Tiehu Li,Hao Li,Alei Dang,Yongkang Han
In this study, a composite material composed of Mg-MOF-74 and graphene oxide (GO) was synthesized to overcome MOFs’ limitations in CO 2 capture. At 273 K/101 kPa, the Mg-MOF-74 composite containing 6 wt% GO achieved 3.46 mmol/g CO 2 uptake and 114.4 CO 2 /N 2 selectivity, demonstrating 25.8 % and 29.3 % enhancements compared with pristine Mg-MOF-74. This enhancement is due to the optimization of CO 2 adsorption by the new pores formed at the interface and the strong affinity of GO functional groups for CO 2 molecules. Furthermore, due to the excellent properties of GO and its strong interaction with Mg-MOF-74, the composites show notable improvements in thermal, adsorption–desorption cycling, and moisture stability. Notably, the Mg-MOF-74 composite containing 6 wt% urea-modified GO exhibits optimal CO 2 adsorption/stability. This is not only due to the synergy between GO and Mg-MOF-74, but also because the amine groups and polar C O bonds in urea can boost adsorption/separation and enhance stability through amine-Mg 2+ coordination. These findings highlight Mg-MOF-74@GO composites as promising candidates for industrial CO 2 capture.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Tong Zhang,Qiaoying Wang,Bingbing Zhang,Zhichao Wu,Zhiwei Wang
Inspired by the simultaneous increase of permeability and selectivity by introducing nanobubbles by physical methods, this study firstly proposed a in situ chemical nanobubbles controlled guanidyl-incorporated double layer nanofiltration (NF) membrane for Mg/Li separation in salt-lake brine. As a bridge, 1,3-diaminoguanidine released nanobubbles rapidly and uniformly by pH control while polymerizing with trimesoyl chloride (TMC) during interfacial polymerization, followed by polyethyleneimine (PEI) secondary reaction, which effectively changed the solute transportation to obtain the shortest pathways in horizontal and normal directions. Compared with conventional PEI-TMC membrane, the water flux of guanidyl-incorporated PEI (G-PEI) membrane was obviously increased by 54.28% while separation factor of Li/Mg ( S Li/Mg ) enhanced by 63.27% in the initial 1 h, indicating chemical nanobubble interlayer effectively broke Trade-off effect by increasing the effective filtration area. In the long-term operation, G-PEI-NF membrane exhibited an excellent S Li/Mg of >60, low mass rate of Mg 2+ and Li + (MLR) of 0.31 and Li + purity of >75% with the stable flux of 19–20 L/(m 2 ·h). This study expected to provide a novel chemical nanobubble interlayer NF membrane with high filtration performance for Mg/Li separation in salt-lake brine.
✓ 已验证
DOI
高影响因子
Energy Technology
·
2019
·Vol. 7
·期 9
·1900454
·
IF 3.163
Xue Li,Yujie Zhang,Jingwei Shen,Shun-an Cao,Ting Li,Fei Xu
Rechargeable Mg batteries are attractive candidates for large-scale energy storage batteries with high safety due to the low-cost and non-dendritic metallic Mg anode. However, exploring high-performance cathode materials is blocking their development. Herein, a high-rate rechargeable Mg battery is established with a AgCl cathode, delivering a high reversible capacity of 70.3 mAh g −1 at 100 mA g −1 , an outstanding rate capability of 32.6 mAh g −1 at 1000 mA g −1 , and a superior long-term cyclability over 500 cycles. Further investigation of the mechanism demonstrates that a conversion reaction takes place between AgCl and metallic Ag 0 for the cathode. The solid-state Mg 2+ diffusion coefficient is as high as 8.1 × 10 −11 cm 2 s −1 , which would be the reason for the high rate capability. The current study reveals significant insights to select promising Mg-storage conversion cathodes by a combination of soft anions and soft transition-metal cations.
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2015
·
IF 3.313
Liuting Zhang,Jiaguang Zheng,Lixin Chen,Xuezhang Xiao,Teng Qin,Yiqun Jiang,Shouquan Li,Hongwei Ge,Qidong Wang
Mg(BH 4 ) 2 is considered as one of the most promising light metal complex hydrides because of its high volumetric and gravimetric hydrogen capacities and world-wide abundance. However, its higher major desorption temperatures (above 300 °C) and poor reaction kinetics have to be improved for the practical application. Herein, Mg(BH 4 ) 2 was successfully synthesized via wet-chemical technique and a significant enhancement in dehydrogenation performance of Mg(BH 4 ) 2 is achieved by the synergetic effect of fluorographite (FGi) and LiBH 4 . Under the effect of FGi, the hydrogen desorption of 6 Mg(BH 4 ) 2 -4FGi composite could be completed below 170 °C in seconds. However, the hydrogen released from 6 Mg(BH 4 ) 2 -4FGi suffers from impurities of B 2 H 6 and HF. More importantly, it is demonstrated that almost all the B 2 H 6 and HF impurities can be suppressed by synergetic modifying Mg(BH 4 ) 2 with FGi and LiBH 4 . The 3 Mg(BH 4 ) 2 –3LiBH 4 -4FGi composite exhibits a capacity over 8.0 wt% H 2 and starts to release hydrogen at 125.7 °C, which is 143.8 °C and 254.3 °C lower than that of pure Mg(BH 4 ) 2 and LiBH 4 , respectively. These significant improvements could be attributed to both the novel morphology that numerous nano-scale borohydride spots formed on the surface of FGi, and the formations of stable fluorides (MgF 2 and LiF) from the interaction between borohydrides and FGi.
✓ 已验证
DOI
高影响因子
Journal of the Australian Ceramic Society
·
2019
·Vol. 56
·期 2
·795-801
·
IF 0.692
Zhang Tao,Wei Yaowu,Chen Junfeng,Li Nan
In spite of the advantages of CaO refractories, such as high refractoriness, potential to produce pure steel molten, and high alkaline corrosion resistance, their application has been limited due to its poor hydration resistance. Introducing additives to improve the hydration resistance of lime is a novel method. The influences of Mg(OH) 2 and sintering temperatures on the sintering and hydration resistance of CaO aggregates that were produced by thermal decomposition were investigated in this paper. The purpose of this work was to produce high-purity CaO raw material with high density, low porosity, well grain growth, and good hydration resistance economically. The sintered samples were characterized by bulk density, apparent porosity, surface appearance, and microstructure. The results indicated that (1) Mg(OH) 2 promoted the grain growth of CaO, reduced the apparent porosity, and improved the density of the specimens. The hydration resistance of the samples was increased. (2) Increasing the sintering temperature improved the hydration resistance of the specimens obviously in the experiment. (3) Grain size of CaO was more uniform with the increment of Mg(OH) 2 content, and the density of the compacts was improved.
✓ 已验证
DOI
高影响因子
Gas Science and Engineering
·
2023
·
IF 0
Guanhua Zhang,Shaocong Mo,Hongtao Xu,Xiaoyu Yan,Binlin Dou,Guomin Cui,Qiguo Yang,Wei Lu
Metal-organic frameworks (MOFs) are popular crystalline materials owing to their high porosity, tunable pore structure, and large surface area. By introducing a carboxylic acid to compete with 2,5-dihydroxyterephthalic acid for magnesium ions in solution, a crystal defect method was used to prepare multi-level pore Mg-MOF-74 with an unregular framework structure of Mg-MOF-74 in this paper. In the prepared samples, the adsorption amounts varied in descending order with various carboxylic acid species: Mg-MOF-74-Propionic acid (37.95 cm 3 /g STP) > Mg-MOF-74 (15.46 cm 3 /g STP) > Mg-MOF-74-Acetic acid (9.19 cm 3 /g STP) > Mg-MOF-74-Formic acid (7.81 cm 3 /g STP). At 1.5 kPa, the CO 2 adsorption of 2,5-dihydroxyterephthalic acid and propionic acid with a ratio of 2:1 can reach 2.78 cm 3 /g STP (standard temperature and pressure) with the comparison to 0.47 cm 3 /g STP of pristine Mg-MOF-74. Under atmospheric pressure, the adsorption capacity of modified Mg-MOF-74 can reach 37.95 cm 3 /g STP, equivalent to 2.45 times of the original Mg-MOF-74.
✓ 已验证
DOI
ACS Sustainable Chemistry & Engineering
·
2024
·
IF 7.1
Zhihong Cui,Peng Chen,Yuping Liu,Lu Zhang,Jingna Nie,Bo Shang,Changguo Chen,Guangsheng Huang,Dingfei Zhang,Fusheng Pan
Rechargeable magnesium batteries (RMBs) are considered as a potential rechargeable for replacing or assisting lithium metal batteries (LMBs). The Mg anode is prone to experiencing a native oxide layer in most electrolytes, resulting in an inferior overpotential and irreversible Mg plating/stripping behavior. Herein, we report for the first time that a novel Mg battery can be assembled using a non-nucleophilic Mg(HMDS)2-based electrolyte with I2 in a relatively large solvent molecule diglyme. An artificial interface phase of MgI2 was constructed in Mg(HMDS)2-AlCl3 electrolyte through the reaction of oxidant I2 and reductant Mg foil. This artificial interface phase is less sensitive to the electrolyte composition. The electrolyte decomposition and the Mg side reaction are effectively inhibited by the MgI2 interphase. In-situ MgI2 interphase significantly lessens the interface impedance and overpotential of the electrochemical Mg deposition/dissolution process. More importantly, the overpotential of the cell using Mg(HMDS)2-2AlCl3- I2/G2 electrolyte is decreased to 0.10 V vs Mg2+/Mg with high Coulombic efficiency of ∼99%, which is superior to the recently reported Mg(HMDS)2-based electrolytes. Besides, the first-principles calculations demonstrate that Mg is uniformly deposited on the MgI2 surface due to reversible Mg plating/stripping, low overpotential, and long-term cycle performance. Note that the as-fabricated novel Ni0.6Co0.4Se2|Mg(HMDS)2-AlCl3- I2/G2|Mg full battery delivers an initial specific capacity of 186 mAh g–1, and retains 120 mAh g–1 with Coulombic efficiency of 100% after 100 cycles. The novel Mg battery verifies the availability of the Mg(HMDS)2-AlCl3- I2/G2 electrolyte through electrolyte additive engineering. The high capacity and stable as-assembled Mg//Ni0.6Co0.4Se2 full cell confirms the compatibility of Mg(HMDS)2 and I2 as well as the utility of modified electrolyte and diselenides cathode materials in RMBs.
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）