TRIBOLOGY INTERNATIONAL
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2025
·
IF 6.9
Shan Huang,Xiaoliang Fang,Yanguo Yin,Wei Liu,Qi Chen,Xiaozeng Guo
Aramid particles (AP) and polytetrafluoroethylene (PTFE) impart tribological application potential to AP/PTFE composites, but weak interfacial bonding and poor formation of high-quality transfer films hinder performance enhancement. In this study, AP was surface-functionalized using a simple, mild, eco-friendly polydopamine (PDA)-polyethylenimine (PEI) synergistic strategy to fabricate AP-PDA-PEI/PTFE composites. Systematic investigations were conducted on their microscopic mechanical properties, tensile strength, tribological performance, and underlying mechanisms. Results indicate that PDA-PEI modification enhances the interfacial microscopic mechanical properties between AP and PTFE. Compared to AP/PTFE, the modified composite’s interfacial modulus is increased by 89.67%. AP 10 -PDA-PEI/PTFE exhibits a tensile strength of 35 MPa, 59.1% higher than AP 10 /PTFE. Characterizations of interfacial microtopography and elemental distribution confirm enhanced interfacial bonding. At 3 MPa, 6.5 MPa, and 10 MPa, AP 10 /PTFE has average friction coefficients of 0.185, 0.157, and 0.150, respectively, with wear rates of ~10 -6 mm 3 /(N·m). In contrast, AP 10 -PDA-PEI/PTFE shows optimal tribological performance: its average friction coefficients are reduced by 15.1%, 12.0%, and 30.2%, with wear rate decreased to ~10 -7 mm 3 /(N·m) (one order of magnitude lower than unmodified AP 10 /PTFE). Wear scar and transfer film characterizations reveal that the composite’s excellent performance stems from the synergy of optimized interfacial bonding and transfer film formation. Enhanced interfacial bonding inhibits AP debonding, while transfer film formation facilitates tribochemical reactions. This transforms the sliding contact mode to tribofilm-transfer film contact, achieving stable, low-wear lubrication.
研究领域:
材料科学
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摩擦学
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聚合物复合材料
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表面工程
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高影响因子
ACS Applied Bio Materials
·
2026
·
IF 5.6
Wenjing Zhang,Xiaoyang Chen,Ziyi Lin,Shangyang Pan,Zufa sabeel,Wenxin Li,Heyun Shen,Zhao Yang
Breast cancer (BC) remains the most prevalent and deadly malignancy among women worldwide. While photothermal therapy (PTT) and chemodynamic therapy (CDT) offer tumor-specific and minimally invasive advantages, their standalone efficacy is limited. Ligustilide (LIG) can exert antitumor effects by generating •O2–, but its bioavailability is poor, thus necessitating improved delivery strategies. Here, we reported a multifunctional nanoplatform (FeD@LIG) integrating PTT, CDT, and chemotherapy for the simultaneous elimination of breast cancer stem cells (BCSCs) and non-BCSCs. FeD@LIG was synthesized via one-step oxidative polymerization of dopamine, co-loading Fe3+ and LIG. The nanospheres exhibited excellent photothermal conversion efficiency (52.8%) and pH/GSH-responsive drug release. Upon near-infrared (NIR) irradiation, FeD@LIG triggered ROS generation via Fenton-like reactions and elevated local temperature, leading to enhanced oxidative stress, apoptosis, and LIG release. In vitro, FeD@LIG reduced cell viabilities of MCF-7 and MDA-MB-231 cells to 12.5 and 7.9%, respectively, and significantly inhibited BCSCs’ self-renewal. In vivo, FeD@LIG achieved a tumor inhibition rate of 92.8% with minimal toxicity. Mechanistic studies revealed activation of the BAX/BCL-2/Caspase-3 pathway and suppression of Hedgehog signaling. Overall, FeD@LIG represents a promising nanotherapeutic strategy for overcoming drug resistance and recurrence by inhibiting both BCSCs and non-BCSCs through multimodal synergistic therapy.
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高影响因子
FIBERS AND POLYMERS
·
2022
·Vol. 23
·期 7
·2030-2041
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IF 2.347
Gou Bin,Xie Congzhen,Wang Rui,Xu Huasong,Zhou Jiangang,Li Licheng
Carbon-based nanofillers reinforced composites with superb mechanical and electric properties are of growing importance in numerous applications. However, the ultra-high conductivities of carbon-based nanofillers will severely degrade the insulating performance of the polymer, restricting the implementation in electronic domain and power system. Herein, core-double-shell carbon nanotubes coated with silica and polydopamine (CNTs@SO@PDA) are prepared, significantly improving the tensile strength of the composite while maintaining its insulating property. Meanwhile, the sandwich-structured composite which is consisted of CNTs@SO@PDA/epoxy as central layer and boron nitride nanosheets coated by polydopamine (BNNS@PDA) filled epoxy as shielding layers achieved excellent breakdown strength of 19.5 kV/mm as well as superb tensile strength of 64.84 MPa, increasing about 13.37 % and 24.24 % compared with neat epoxy respectively. The simulation results demonstrate the electric field optimization and redistribution effect of sandwich-structured nanocomposites. This work provides a method for fabricating epoxy nanocomposite with marvelous mechanical and insulating properties, which can be applied to future electronic protectors and insulation equipment.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2022
·
IF 9.136
Zhiqiang Guo,Lei Sun,Hui Hou,Jian Zhou,Yuan Li,Liangliang Hu,Jinzhang Xu
The preparation of the maple leaf-like MnO 2 –SiO 2 @PDA biomimetic composites not only overcame the problem of easy agglomeration of nanoparticles, but also provided rich functional groups, large specific surface areas and good stability, achieving the efficient sorption of Cu(II), Cd(II) and Ni(II) from aqueous solution. The maximum sorption capacities of the MnO 2 –SiO 2 @PDA towards Cu(II), Cd(II) and Ni(II) attained from the Langmuir model were 218.788, 383.420 and 148.939 mg·g −1 , respectively. The sorption of Cu(II), Cd(II) and Ni(II) on the MnO 2 –SiO 2 @PDA were strongly affected by pH, but not by ionic strength, showing good resistance to salt interference. The main sorption mechanism of the MnO 2 –SiO 2 @PDA towards Cu(II), Cd(II) and Ni(II) was the strong surface complexation of the functional groups on the MnO 2 –SiO 2 @PDA with Cu(II), Cd(II) and Ni(II). Moreover, the radii of Cu(II), Cd(II) and Ni(II) ions and their complexation strength with the MnO 2 –SiO 2 @PDA jointly determined the order of the competitive sorption capacities as Cu(II) > Cd(II) > Ni(II). Given the above analyses, the maple leaf-like MnO 2 –SiO 2 @PDA biomimetic composites have excellent application prospects in practical wastewater treatment.
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Foods
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2022
·Vol. 11
·期 3
·386
·
IF 5.561
Ying Xu,Xuan Yu,Jiaqi Gui,Yiqun Wan,Jinping Chen,Ting Tan,Fan Liu,Lan Guo
A rapid and effective ultra-high performance liquid chromatography (UHPLC) method was developed for the determination of five anthraquinones (emodin, physcion, aloe-emodin, rhein, and chrysophanol) inPolygonum multiflorum. The target compounds were ultrasonically extracted with 70% methanol, followed by dispersive solid-phase extraction (d-SPE) with HC-C18 and desorption with acetonitrile. The five anthraquinones were separated on an ACQUITY UPLC®HSS T3 column (2.1 × 100 mm, 1.8 μm) and detected by a photodiode array detector (PDA) at 254 nm. Under the optimized conditions, linear relationships were achieved in the range of 0.3~100 mg/L for emodin, 0.3~40 mg/L for physcion, 0.1~20 mg/L for aloe-emodin, and 0.05~20 mg/L for rhein and chrysophanol. The limits of detection of the five analytes ranged from 0.01 to 0.08 mg/L, and the recoveries were within the range of 82.8~118.4% with an RSD (n= 6) of 1.0~10.3%. The intra-day and inter-day precision (n= 5) of the five targets were in the range of 1.0~1.8% and 3.0~3.1%, respectively. Furthermore, this method was applied to analyses ofPolygonum multiflorumsamples collected from different regions in China with satisfactory results. All the results indicated that this method is suitable for the detection of five anthraquinones inPolygonum multiflorum.Keywords:anthraquinones;Polygonum multiflorum;d-SPE;UHPLC
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FOOD RESEARCH INTERNATIONAL
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2026
·
IF 8.8
Yuanyuan Zhao,Yongmao Lu,Tian Yang,Shaohua Hu,Yuanyuan Yan,Xingguo Wang,Wei Wei
Multi-method strategy enhances accuracy in human milk vitamin research. • Mass spectrometry achieved precise 25(OH)D₂/₃ quantification in human milk. • Immunoassays offered rapid screening but showed a 72.98% positive bias. • Liquid chromatography profiled vitamins A and E but lacked sensitivity for D and K. • 25(OH)D₃ increased slightly, while 25(OH)D₂ declined across lactational stages. Accurate analysis of vitamin D in human milk is essential for infant nutrition but remains analytically challenging due to low levels and a complex matrix. This study evaluates a practical multi-method strategy using LC-MS/MS, ELISA, and UPLC-PDA for vitamin D analysis in human milk. LC-MS/MS precisely quantified 25(OH)D₂ and 25(OH)D₃ with assay LOQ of 0.045 ng/mL and 0.100 ng/mL, respectively. ELISA showed a 11.58 ng/mL positive bias of vitamin D which limits use for accurate quantification. UPLC-PDA profiled vitamins A and E effectively but lacked sensitivity for vitamin D. Longitudinally, LC-MS/MS results show 25(OH)D₃ and total 25(OH)D concentrations remained relatively stable, with medians ranging from 0.141 to 0.281 ng/mL and 0.263 to 0.315 ng/mL, respectively, across the study period, while 25(OH)D₂ peaked at 8 weeks before declining. This study establishes LC-MS/MS as the preferred analytical strategy for quantifying 25(OH)D 2 and 25(OH)D 3 in human milk, providing critical data to assess infant nutritional intake and guide clinical interventions. Download: Download high-res image (160KB) Download: Download full-size image
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FOOD CHEMISTRY
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2026
·
IF 9.8
Shuo Yang,Jinglong Qu,Yang Qin,Shuaibing An,Kaiqiang Huang,Yaling Wei,Jun Xi
Ara h 3, a prevalent peanut allergy, presents a considerable risk to public health. Preventing exposure to food allergens is the paramount method for safeguarding those with allergies. Consequently, we devised a polydopamine (PDA)-modulated gold self-coupling technique to fabricate plasmonic blackbodies (AuNBs@PDA) featuring multibranched configurations. High-performance SERS labels are possible using AuNBs@PDA's PDA coating and multi-branched design. It detects Ara h 3 ultra-sensitively in lateral flow immunochromatographic test strips (LFIA). SERS-LFIA has outstanding specificity, stability, and reproducibility, with a test strip shelf life of over a year and a LOD of 72.2 pg/mL, 295 times higher than standard AuNPs-LFIA. Implementing this technology accurately detects food samples. This sensitive and reliable platform for Ara h 3 detection has great potential for food allergy monitoring.
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高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Simin Wang,Huijuan Xiu,Dingwen Yin,Jinbao Li,Gengmei Liu,Yuxin Qin,Feiguo Hua,Qingjun Meng,Minzhe Wu,Mengxia Shen
Achieving high shielding effectiveness in electromagnetic shielding materials relies heavily on high conductivity, yet simultaneously enhancing the absorption loss remains a persistent challenge. Consequently, the study successfully creates efficient electromagnetic shielding composite films with a unique grape-like bunch structure of hollow nanosilver (HCAF) through layer-by-layer assembly. The utilization of poly(dopamine) (PDA) to anchor nanosilver granules (AgNPs) onto cellulose nanofibers (CNF) results in the formation of CNF@PDA@AgNPs. Subsequently, a surface protection etching method is employed to etch the AgNPs, resulting in hollow nanosilver (H-AgNPs) and the generation of CNF@PDA@H-AgNPs. A composite film featuring a grape bunch structure is fabricated by interweaving high aspect ratio CNF with CNF@PDA@H-AgNPs. A substantial quantity of H-AgNPs creates an abundant interface, while the grape bunch structure establishes an efficient conductive network. That enables the composite film to exhibit excellent impedance matching, excellent conductivity loss, abundant polarization loss, and multiple reflection loss. Therefore, the conductivity of the composite film with a thickness of 148.8 μm reaches 212660 S/m, with SET, SEA, and SER 89.56, 79.03, and 10.53 dB in the X band, significantly better than the 76.9, 55.55, and 21.41 dB of the solid AgNPs composite film. The composite film also exhibits remarkable thermal conductivity (The coefficients of in-plane and out-plane thermal conductivity are 4.61 and 0.17 W/(m·K), respectively), mechanical properties, and strain sensing capabilities, making it significant potential for applications in flexible electronics and other related fields.
研究领域:
材料科学
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纳米技术
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电磁干扰屏蔽
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柔性电子
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热管理
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传感器
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高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Lun Han,Xu Wang,Bin Yu,Xiaoyuan Qin,Baocheng Liu,Xu Han,Huifen Yuan,Bin Yu,Zhiqi Zhao
Glucose is a key biomarker of diabetes, and effective glucose monitoring methods are crucial to the prevention and management of diabetes. Therefore, in this paper, Fe 3 O 4 /DEX/PDA@Au (Raman reporters) @Au nanocomposites were synthetized that with DTNB (5,5′-dithiobis(2-nitrobenzoic)), MMTA (2-mercapto-4-methyl-5-thiazole acetic acid), MBA (4-mercaptobenzoic acid) and 4-Mpy(4-Mercaptopyridine) were used separately as Raman reporters. Fe 3 O 4 and PDA (Polymerized dopamine) could supply more high surface area of active sites and high SERS (Surface-Enhanced Raman Scattering) substrate, which has high stability and reproducibility. Dextran coating is an effective way to prepare biocompatible materials TEM, XRD, TG and VSM were used to analyze the size, morphology and magnetic properties of the nanocomposites. Fe 3 O 4 /DEX/PDA@Au(Raman reporters)@Au that integrates a multi-hotspot structure and magnetic separation techniques were studied the enhancement effect of Raman spectra, and glucose solutions with different concentrations were tested. Furthermore, the optimal Fe 3 O 4 /DEX/PDA@Au(Raman reporters)@Au nanocomposites were supplied as SERS substrates for detection of glucose accurately and quickly in sweat. SERS signal intensity is linearly correlated with glucose concentration within the measurement range of 5 × 10 -3 to 10 mM, and the minimum detectable concentration is 5 µM. The Fe 3 O 4 /DEX/PDA@Au(Raman reporters)@Au nanocomposites exhibit high reliability, specificity and repeatability of the strategy were then verified by practical detection of sweat.
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高影响因子
Advanced Therapeutics
·
2024
·
IF 3.7
Ran Bin,Chen Zhu,Rao Yunjia,Yan Jin,Wang Jie,Xiao Dongqin,Lin Tao,Feng Gang
Upon progression to the metastatic stage, prostate tumors commonly exhibit multi-drug resistance. Combining multiple treatment protocols can be beneficial in overcoming this resistance, which is often attributed to tumor heterogeneity. Recently, nano-photosensitizer-mediated photothermal therapy is shown to inhibit tumor growth through multiple pathways, including thermal ablation and activation of the antitumor immune response. In this study, gold nanoparticles (Au) are selected as the core photosensitizer. Then, the photothermal conversion of Au is augmented through dopamine coating, and the chemotherapy drug doxorubicin (DOX) is grafted to the dopamine coating. The release of DOX from DOX-loaded dopamine-modified gold nanoparticles (Au@PDA@DOX) occurred in response to an acidic environment. The combination of chemotherapy and thermal ablation better inhibits the growth, migration, and invasion of tumor cells and induced tumor cell apoptosis and necrosis in vitro. More importantly, thermal ablation induces the immunogenic death of prostate tumor cells (RM-1) cells. The transition of prostate tumors from a “cold” to a “hot” tumor with immunogenicity is observed. The combination effectively activates the antitumor immune response, inhibits tumor growth, and alleviated bone damage by tumors in vivo. It is indicated that Au@PDA@DOX nanoparticles will offer a novel treatment protocol for prostate tumor bone metastases.
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MACROMOLECULAR MATERIALS AND ENGINEERING
·
2019
·Vol. 304
·期 8
·1900176
·
IF 3.038
Shixin Song,Shan Xia,Yingcong Wei,Xue Lv,Shulin Sun,Quanming Li
Poly(methyl methacrylate)-grafted carbon nanotubes (PMMA@MWCNTs) are nondestructively prepared via the integration of mussel-inspired polydopamine (PDA) chemistry and the surface-initiated atom transfer radical polymerization (ATRP) method. The structures and properties of the poly(vinylidene fluoride)-based (PVDF-based) nanocomposites filled with pristine MWCNTs and PMMA@MWCNTs are investigated. The results show that the encapsulation of PMMA on the MWCNTs surface not only improves the dispersibility of MWCNTs in the PVDF matrix but also enhances the interfacial interaction between MWCNTs and PVDF. The addition of PMMA@MWCNTs nanofillers to PVDF can effectively induce the crystal structure of PVDF to transform from the α-phase to the β/γ -phase, and nearly 100% β/γ -phase PVDF formed when the nanofiller loading is higher than 5 wt%. Compared with the MWCNTs/PVDF composites, the PMMA@MWCNTs/PVDF composites exhibit obvious improvement in the percolation threshold because the PMMA shells hinder the direct contact of the MWCNTs. Moreover, the loss tangent of the PMMA@MWCNTs/PVDF composites is effectively suppressed due to the reduced leakage current in the composites and the enhanced interfacial strength between the nanofiller and the matrix.
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Materials Today Communications
·
2024
·
IF 3.7
Tianlu Li,Aixian Tian,Wei Li,Yun Zhao,Minfang Chen
A one-step hydrothermal method was used to deposit a in situ composite coating on a magnesium alloy by adding ZIF-8 nanoparticles modified by polydopamine (PDA) (PDA@ZIF-8) as a photoabsorbing agent and growing Mg-Al double-layer hydroxide (LDH). The results showed that PDA@ZIF-8 nanoparticles had significant influence on the corrosion resistance, antibacterial properties, and biocompatibility of the LDH coating, and improved the compactness and crystallinity of LDH by regulating the growth of its lamella. Compared with the LDH coating, the corrosion current density of the composite coating by adding PDA@ZIF-8 nanoparticles was reduced from 2.28×10 -5 to 1.86×10 −6 A·cm -2 . And its immersion corrosion rates were 0.89 ± 0.05 mm·year −1 in SBF solution for 8 days. Meanwhile, it had antibacterial efficacy of 99.99% and 99.99% against Escherichia coli and Staphylococcus aureus , respectively, with the in vitro photothermal conversion efficiency of 29.77%. Moreover, besides greatly improving osteogenic activity and biocompatibility in vitro, the composite coating with the addtion of PDA@ZIF-8 nanoparticlescan also drive M1-type macrophages to M2-biased phenotypes after exposure to 808 nm NIR light, changing in macrophage secretion for tissue regeneration, and fulfill the excellent antibacterial properties in vivo antibacterial implantation test. This method can provide an effective way and strategy for regulating and enhancing the antibacterial functionalization and improving the corrosion resistance of the double-layer hydroxide coating on the surface of magnesium alloys.
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