JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
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2022
·Vol. 111
·期 3
·404-414
·
IF 4.854
Xiaoxue Wang,Jingliang Wu,Min Wang,Chunbo Lu,Wenfang Li,Qiao Lu,Yanying Li,Bo Lian,Bo Zhang
Recent efforts have focused on preparing drug-loaded hydrogel for wound healing. In order to obtain an ideal hydrogel dressing for skin wound repair, a carboxymethyl chitosan-gelatin hydrogel was prepared for co-delivery of SP (substance P) and DMOG (dimethyloxallyl glycine) by a chemical cross-linking method using genipin as the cross-linking agent. The synthesized hydrogels have good biocompatibility and physicochemical properties due to the low toxicity of the hydrogel material. The three-dimensional network structure of the hydrogels supports cell migration and proliferation, and the combination of SP and DMOG drugs exhibited strong effects on cell proliferation. Moreover, the co-loaded drug hydrogels could significantly promote wound healing in vivo, and provide a potential hydrogel for wound healing.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2022
·Vol. 140
·期 1
·e53261
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IF 3.057
Shangru Cheng,Yaokai Tang,Qiangmin Gao,Xincheng Wang,Anqi Li,Yingxin Yuan,Shanshan Guan
A longstanding challenge in fabricating high-dielectric polymer composite is how to rationalize structure design to improve dielectric constant while minimizing dielectric loss. In this work, we provide a critical material design concept for high-performance flexible dielectric nanocomposite (PCGA) based on backfilling polydimethylsiloxane (PDMS) matrix into the pre-constructed chitosan-reduced graphene oxide (rGO) aerogel with 3D conductive network. Herein, the 3D conductive network enables PCGA to achieve the percolation threshold with a small amount of rGO, which improving the dielectric constant. Simultaneously, the chitosan insulating barrier layer prevents the generation of leakage current between conductive fillers interfaces, which suppressing the losses of the PCGA, thus ensuring the balance between dielectric constant and loss. The results demonstrated that the PCGA (0.06 g rGO) exhibited a dielectric constant as high as 297.3 and a loss tangent as low as 1.91. Subsequently, the as-obtained PCGA composites as a dielectric interlayer was employed for preparing capacitive sensor. The results demonstrated that the sensor possesses a desirable integration of high sensitivity (5.8% kPa −1 in the pressure range 0–7 kPa) and wide work range (0–140 kPa) due to the synergistic effect of the excellent mechanical performance along with high-dielectric constant and suppressed loss.
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Materials
·
2022
·Vol. 15
·期 20
·7156
·
IF 3.748
Huimei Shan,Yunquan Liu,Chunya Zeng,Sanxi Peng,Hongbin Zhan
A magnetite graphene oxide chitosan (MGOCS) composite microsphere was specifically prepared to efficiently adsorb As(III) from aqueous solutions. The characterization analysis of BET, XRD, VSM, TG, FTIR, XPS, and SEM-EDS was used to identify the characteristics and adsorption mechanism. Batch experiments were carried out to determine the effects of the operational parameters and to evaluate the adsorption kinetic and equilibrium isotherm. The results show that the MGOCS composite microsphere with a particle size of about 1.5 mm can be prepared by a straightforward method of dropping FeCl2, graphene oxide (GO), and chitosan (CS) mixtures into NaOH solutions and then drying the mixed solutions at 45 °C. The produced MGOCS had a strong thermal stability with a mass loss of <30% below 620 °C. The specific surface area and saturation magnetization of the produced MGOCS was 66.85 m2/g and 24.35 emu/g, respectively. The As(III) adsorption capacity (Qe) and removal efficiency (Re) was only 0.25 mg/g and 5.81% for GOCS, respectively. After 0.08 mol of Fe3O4modification, more than 53% of As(III) was efficiently removed by the formed MGOCS from aqueous solutions over a wide pH range of 5–10, and this was almost unaffected by temperature. The coexisting ion of PO43−decreasedQefrom 3.81 mg/g to 1.32 mg/g, but Mn2+increasedQefrom 3.50 mg/g to 4.19 mg/g. The As(III) adsorption fitted the best to the pseudo-second-order kinetic model, and the maximumQewas 20.72 mg/g as fitted by the Sips model. After four times regeneration, theRevalue of As(III) slightly decreased from 76.2% to 73.8%, and no secondary pollution of Fe happened. Chemisorption is the major mechanism for As(III) adsorption, and As(III) was adsorbed on the surface and interior of the MGOCS, while the adsorbed As(III) was partially oxidized to As(V) accompanied by the reduction of Fe(III) to Fe(II). The produced As(V) was further adsorbed through ligand exchange (by forming Fe–O–As complexes) and electrostatic attraction, enhancing the As(III) removal. As an easily prepared and environmental-friendly composite, MGOCS not only greatly adsorbs As(III) but also effectively removes Cr(VI) and As(V) (Re> 60%) and other metals, showing a great advantage in the treatment of heavy metal-contaminated water.Keywords:chitosan;graphene oxide;magnetite;As(III) removal
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ENVIRONMENTAL ENGINEERING SCIENCE
·
2022
·Vol. 39
·期 12
·907-917
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IF 2.172
Peng Wan,Xuanning Yang,Qinhua Feng,Shuyu Shi,Baolin Deng,Lina Zhang
Efficient separation of oil droplets from oil/water emulsions is necessary for many energy and food industrial processes and for industrial wastewater treatment. Membrane microfiltration has been explored to address this issue because it is simple to operate and low in cost. However, filtration of oil droplets with a size around or less than 1 μm is still a major challenge. Furthermore, the fabrication process for polymeric membranes often uses hazardous organic solvents and petroleum-derived and nonbiodegradable raw materials, which pose additional environmental health and safety risk. In this study, we examined the use of chitosan-based membranes to efficiently remove oil droplets with an average diameter of ∼1 μm. The membranes were fabricated based on the rapid dissolution of chitosan in an alkaline/urea solvent system at a low temperature, thus avoiding the use of any toxic organic solvent. The chitosan membranes were further modified by dopamine and tannic acid (TA). The as-prepared membrane was characterized in terms of surface morphology, pore size distribution, and mechanical strength. The membrane performance was evaluated on a custom-designed crossflow filtration system. The results showed that the modified chitosan membrane with dopamine and TA had a water flux of 230.9 LMH at 1bar transmembrane pressure and oil droplet rejection of 99%. This water flux represented an increase of more than 10 times when compared with the original chitosan membrane without modification. The study also demonstrated excellent antifouling properties of the modified membrane that could achieve near 100% water flux recovery.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Shu Xie,Tianwei Dai,Fei Li,Fengyi Liu,Quanqing Xu,Aixin Zhu,Xufeng Zhang
Hybrid hydrogels containing biomacromolecules have been widely used in sensors, fluorescent probes , and other fields due to their high biocompatibility and nontoxicity. In this paper, tough hydrogels with interconnected macro-pores have been fabricated by freeze-induced chemical cross-linking of microfibrillated cellulose (MFC) and organic modified chitosan (CS). In this hydrogel materials, three-dimensional networks were formed by abundant hydrogen bonds and chemical cross-linking. Luminescent lanthanide complexes were covalently bonded to the hydrogel networks through coordination of Eu 3+ ions with 2, 3-pyridine dicarboxylic acid modified chitosan. The luminescence of hydrogel materials was further improved by the replacement of coordination water with 2-thiophenyltrifluoroacetone (TTA). The prepared hydrogels showed excellent shape memory properties both under water and in air. The stress of the hybrid hydrogel at 80 % strain can reach 159 kPa, which is much higher than that of the traditional microfibrillated cellulose-based hydrogels. The obtained luminescent hybrid hydrogels exhibited an excellent fluorescence detection effect on formaldehyde. The detection limit for formaldehyde is 45.7 ppb, which is much lower than the WHO standard (80 ppb for indoor air). The novel, facile preparing procedure may extend the potential applications of hybrid lanthanide luminescent hydrogel as fluorescence probes for pollution monitoring, especially for formaldehyde and other organic aldehydes.
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LANGMUIR
·
2023
·
IF 3.9
Xingrui Qi,Jiamin Gan,Zhidong Zhao,Nian Li,Yufang Chen,Tao Jin
One of the potential treatments for bacterial wound infections is photodynamic therapy. WO3–x semiconductor materials can generate reactive oxygen species when exposed to light, which can inactivate bacteria. In this work, we improved their photocatalytic performance by doping WO3–x with Cu. The wound dressing was prepared by loading Cu–WO3–x into a highly biocompatible chitosan sponge. The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing. Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.
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Journal of Water Process Engineering
·
2022
·
IF 7.34
Yonglei Wang,Xinglin Wang,Liping Tian,Yanan Li,Guilin He,Haiyang Yu,Hua Qi,Wentao Sun
Algal blooms in lake and reservoir water lead to water quality problems, including water odors, algal toxins, and disinfection byproducts . A novel dissolved air flotation process that incorporates positively charged bubbles (PosiDAF) can effectively remove algae in lakes and reservoirs. Chitosan, as a modified bubble agent in the PosiDAF process, has attracted extensive attention due to its natural nontoxicity and good flocculation properties. In this paper, three types of amphiphilic chitosan with different lengths of carbon chains were prepared via amphiphilic modification and were used as bubble modifiers to remove microcystis aeruginosa in the PosiDAF process. The effects of algae removal under different dosage of modifiers were compared, and the role of algal organic matter was investigated. Results showed that the water solubility of chitosan was markedly enhanced after amphiphilic modification, while thermal stability were decreased. When using butyl-N-2 hydroxypropyl trimethyl chitosan ammonium chloride (C4-HTCC), the effect of modified air flotation was the best, and the removal ratio of algae was 93.47% when the C4-HTCC dosage was 1.0 mg/L. The presence of AOM enhanced the overall effect of algae removal, and electrostatic attraction was the primary adhesion mechanism of the microbubble-amphiphilic chitosan-algal organic matter-algal cell system. In addition, adsorption bridging and net trapping also have positive effects on algae removal.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2022
·Vol. 23
·期 4
·2080
·
IF 6.208
Zhaoqian Fan,Yukun Qin,Song Liu,Ronge Xing,Huahua Yu,Kecheng Li,Pengcheng Li
The exploration of novel, environmentally friendly, and efficient nematicides is essential, and modifying natural biomacromolecules is one feasible approach. In this study, 6-O-(trifluorobutenyl-oxadiazol)-chitosan oligosaccharide derivative was synthesized and characterized by FTIR, NMR, and TG/DTG. Its bioactivity and action mode against root-knot nematodeM. incognitawere estimated. The results show that the derivative shows high nematicidal activity against J2s, and egg hatching inhibitory activity at 1 mg/mL. The derivative may affect nematode ROS metabolism and further damage intestinal tissue to kill nematode. Meanwhile, by synergism with improving crop resistance, the derivative performed a high control effect on the nematode with low phytotoxicity. These findings suggested that chitosan oligosaccharide derivatives bearing fluoroalkenyl groups are promising green nematicides.Keywords:chitosan oligosaccharide;nematicide;Meloidogyne incognita;trifluorobutenyl group
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ACS Omega
·
2022
·
IF 4.132
Chunpo Gao,Yanan Wang,Jiasheng Shi,Yanyan Wang,Xiaoli Huang,Xilu Chen,Zhiyong Chen,Yunfeng Xie,Yanzhao Yang
Chitosan is a typical hydrophilic biomass building block widely used in material science and engineering. However, its intrinsic amphiphilicity has been seldom noted so far. Herein, a series of glutaraldehyde-crosslinked chitosan cryogels with superamphiphilicity are fabricated at moderately frozen conditions through a freezing–thawing process. The micron-sized porous cryogel samples display a 0° contact angle toward both water and oil, 0° water contact angle under oil, and over 120° oil contact angle underwater. By comparing the wetting behavior of the tablet compressed by pure chitosan powders, the superamphiphilicity of the chitosan sample is proven to be independent on crosslinkers. This special wettability endows the chitosan cryogels with high separation efficiency for various surfactant-stabilized oil-in-water emulsions under continuous flow mode driven by gravity as well as a peristaltic pump.
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CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Jinghui Jiang,Xiaoxia Chen,Gong-Liang Zhang,Hongshun Hao,Hong-Man Hou,Jingran Bi
To improve the mechanical and barrier properties of cellulose and chitosan (CS) and to allow the application of volatile antibacterial benzyl isothiocyanate (BITC) in active packaging, a double-layer nanocomposite film was prepared. Cellulose nanofibers (CNF) were crosslinked with CS via genipin to build the substrate. Quaternized cellulose nanocrystals (QCNC) were synthesized for carrying BITC as the coating material . By the layer-by-layer self-assembly approach, CS-CNF/QCNC-BITC film was fabricated. This film possessed the tensile strength of 33.75 MPa, low permeabilities of oxygen (6.9 × 10 −17 m 3 /s·m·Pa) and moisture (1.2 × 10 −11 g/s·m·Pa), and good antibacterial activity with the inhibition zone diameters of 4.9, 4.2 and 2.7 cm against Escherichia coli , Salmonella typhimurium and Staphylococcus aureus . The total viable count , total volatile basic nitrogen and thiobarbituric acid-reactive substances of the chicken wrapped CS-CNF/QCNC-BITC were only 4.4 log CFU/g, 17.7 mg/100 g and 0.44 mg/kg at 14 days, indicating a potential application of CS-CNF/QCNC-BITC for food packaging.
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CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Chen Huang,Fusheng Sun,Xuxi Ma,Chao Gao,Nan Yang,Katsuyoshi Nishinari
Food-grade microgel-stabilized emulsions have been attracting much attention due to their promising applications in food formulations. In this study, the use of hydrophobically modified chitosan microgels ( h -CSMs) as particle emulsifiers to stabilize high internal phase emulsions (HIPEs) was demonstrated for the first time. Four hydrophobically modified chitosan ( h -CS) were obtained by grafting deoxycholic acid (DA) with chitosan (CS) at grafting rates of 4.64%, 13.21%, 15.12% and 30.29%, respectively. The selected modified chitosan were further cross-linked with sodium tripolyphosphate (TPP) to form h -CSMs. It was found that, compared to pure CS and the modified h -CS, the h -CSMs have higher hydrophobicity , and can stabilize oil-in-water HIPEs effectively. The interfacial properties of the h -CSMs, and the formation, microstructure and rheological properties of HIPEs were characterized by dynamic interfacial adsorption, contact angle, visual observation, laser confocal microscopy and rheological measurements, respectively. The results show that stable HIPEs with oil concentration up to 90 wt% can be formed using very low h -CSM particle concentration (only 0.05 wt% for the HIPE with 90 wt% oil), and the HIPEs stabilized by h -CSMs displayed higher rheological compliance than other solid particle stabilized HIPEs at high oil volume fraction. The strong emulsification properties of the h -CSMs are attributed to their increased hydrophobicity, the enhanced exposure of hydrophobic groups during microgelation process, and the viscoelasticity of h -CSMs.
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CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Long Xia,Juguo Dai,Xiaohong Wang,Mingjin Xue,Yiting Xu,Conghui Yuan,Lizong Dai
Multifunctional cotton fabrics (M-CF) have important application prospects in intelligent home decoration and material packaging. In this work, nanoparticles (AgNC@BP) were prepared by coating the surface of silver nanocubes (AgNCs) with borate polymer. Subsequently, M-CF with electromagnetic wave (EMW) absorption, mechanical enhancement, flame-retardancy and antibacterial performances were prepared by immersing cotton fabrics (CF) into AgNC@BP/crosslinked chitosan (CS) solution. Expectantly, AgNC@BP endows AgNC@BP/CS-CF with good flame retardancy and low combustion heat release. That is, the char length of AgNC@BP/CS-CF is 7.9 cm after the vertical burning test (UL-94 V) and the peak heat release rate (pHRR) of AgNC@BP/CS-CF is reduced by 21.4% compared to pure CF. Meanwhile, the tensile strength of AgNC@BP/CS-CF is 18.8% higher than that of CF. Synchronously, the introduction of AgNC@BP can also endow M-CF with better EMW absorption, mechanical and antibacterial properties . In conclusion, this work provides a tactic for fabricating M-CF.
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