CHEMOSPHERE
·
2024
·
IF 8.1
Shuting Shi,Chuanqin Zhou,Aiting Chen,Nana Tang,Kun Wan,Youwei Jiang,Jun Liu,Quanguo He,Li Cao
Antibiotics have emerged as a class of contaminants of concern globally, raising widespread worry and unease, primarily because of their inappropriately use and endless migration in food chains. Electrochemical ultrasensitive and selective determination of norfloxacin (NOR) using bismuth-based bimetallic salt bismuth molybdate (Bi 2 MoO 6 ) and carboxylated multi-walled carbon nanotube (MWCNTs-COOH) hybrid electrode as sensing platforms is presented hereby. The electrocatalytic ability of the electrodes was verified to be enhanced by the synergy effect of both Bi 2 MoO 6 and MWCNTs-COOH using cyclic voltammetry and electrochemical impedance spectroscopy. Linear scan voltammetry was applied to detect NOR. The oxidation peak current was linearly correlated with NOR concentration of 0.03–10 μM and the low limit detection of the optimized method was 6.7 nM (S/N = 3). In addition, it was verified that Bi 2 MoO 6 /MWCNTs-COOH/GCE probe had good stability, reproducibility, repeatability and selectivity. The spiked recovery method for NOR in milk and lake water samples showed recoveries of 94.8 – 96.9% and 90.2 – 98.3%, respectively, which can be used to determine NOR in real samples with high sensitivity. The preparation of Bi 2 MoO 6 /MWCNTs-COOH/GCE provides a new prototype for probing NOR detection at nanomolar concentration and safeguarding antibiotic contamination in environmental and food chains.
研究领域:
环境科学
·
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Na Liu,Youwei Jiang,Quanguo He,Tao Zhang,Yao Ping,Yelong Jiang,Wu Wang,Qijun Xie,Jianhua Ding
As an oral prodrug, valacyclovir undergoes rapid in vivo hydrolysis to form acyclovir - an agent with antiviral properties. This compound is extensively employed in addressing herpes virus infections and various other related conditions. Therefore, there is an urgent need to develop a method for detecting the content of valacyclovir in drugs. In this study, molybdenum disulfide (MoS 2 ) and carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) were ultrasonically dispersed to prepare a suspension, which was drop-coated on the surface of a pretreated glassy carbon electrode (GCE). A MoS 2 /MWCNTs-COOH/GCE sensing platform was successfully constructed for the ultrasensitive detection of valacyclovir. Under optimized conditions, cyclic voltammetry (CV) was used to detect valacyclovir. A strong linear correlation between the oxidation peak current and the concentration was observed within the range of 0.1–40.0 μM, with a detection limit (LOD) of 0.013 μM. Meanwhile, the sensing platform also demonstrated excellent anti-interference capability, stability, and reproducibility. In the analysis of real samples, satisfactory recoveries for valacyclovir (96.5–104.0%) were achieved with a relative standard deviation (RSD) below 5.0%, further confirming its reliability. In summary, the developed MoS 2 /MWCNTs-COOH/GCE sensor offers a promising approach for the highly sensitive detection of valacyclovir.
✓ 已验证
产品关联
DOI
高影响因子
IEEE SENSORS JOURNAL
·
2026
·
IF 4.5
Shingping Zhou,Pingxin Ge,Yu Zhang,Zhong Wang,Xin Yi,Qing Zheng,Wei Ma,Gebo Pan,Shaohui Zhang
Osteocalcin, a key biomarker of bone metabolism, is of significant clinical value for the diagnosis and management of osteoporosis through dynamic monitoring. The development of highly sensitive detection methods is therefore of great importance. This study developed a highly sensitive electrochemical immunosensor for osteocalcin detection based on a nanocomposite of carboxylated multi-walled carbon nanotubes (MWCNT-COOH), polyvinyl alcohol (PVA), and poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS). A uniform and stable nanocomposite film was prepared via a simple and rapid method involving physical blending and vortex dispersion. Osteocalcin (OC) antibodies were covalently immobilized onto the surface of a functionalized screen-printed electrode using an EDC/NHS coupling system. The detection principle relies on the specific antigen-antibody binding event hindering interfacial electron transfer, enabling the quantitative detection of OC via differential pulse voltammetry (DPV). Under optimal conditions, the sensor exhibited an excellent linear response (R² = 0.996) over a concentration range from 10 pg/mL to 100 μg/mL, with a detection limit of 1.2 pg/mL. Furthermore, the sensor demonstrated outstanding selectivity, reproducibility, and stability, showcasing its potential as a promising tool for the quantitative analysis of bone metabolism biomarkers in biological fluids.
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Polymer Materials
·
2025
·
IF 4.7
Jinpeng Liu,Chengcheng Hao,Huili Zhang,Hongyu Chen,Ling Zhang,Xiaodong Chen,Jianye Wang,Maohuai Wang,Shuxian Wei,Xiaoqing Lu,Zhaojie Wang,Siyuan Liu
Covalent organic frameworks (COFs) have become potential candidates for gas purification technology, especially in carbon capture and storage applications. By utilizing strategies such as pore structure design and functional modification, COFs have been developed to exhibit high selectivity and superior adsorption capacity for the effective capture and separation of CO2 from industrial waste gases. Notably, alkali metals exhibit strong interactions with the backbone of the COFs, which can enhance the CO2/N2 adsorption separation performance of these porous materials. This study details the synthesis of two-dimensional COF materials modified with acidic groups (TpPa-COOH and TpPa-SO3H) via mechanical grinding. Alkali metals such as Na, Li, and K were introduced into these groups through simple ion exchange reactions, thereby creating metal-modified COF materials. The impact of various alkali metals on the CO2/N2 adsorption separation performance of COF materials was investigated. Among the resulting products, lithiated TpPa-COOH showed the highest CO2 capture capacity of 2.65 mmol/g at 273 K and 1 bar. This may be due to the smaller atomic size of Li that offers larger adsorption space. Under the same conditions, the K-modified TpPa-SO3H exhibited the highest selectivity of 548, which surpasses most COFs reported in the literature. The superior performance was caused by the high polarization of the COF backbone triggered by the alkali metals. The inference was further confirmed by computational simulations. This work provides a facile method for the modification of porous materials with alkali metals to achieve superior gas separation performance.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Jing Hu,Qin Ren,Dongqing Fan,Wenbo Wu,Xiaoying Zhang,Dongxin Wang,Junxiu Zhao,Ping Zhang,Xiangjun Li,Liangpo Liu,Jisheng Nie,Hong Cui
Metal–organic gel (MOG) is a distinctive metal–organic hybrid material with a unique porous structure and exceptional catalytic site accessibility. The rational design of an electrochemical and colorimetric dual-mode sensor platform utilizing the peroxidase (POD)-like activity of MOG for the detection of H2O2 is crucial for clinical diagnosis. In this article, a two-dimensional composite nanozyme based on Fe-MOG and carboxylated graphene oxide (GO-COOH) was synthesized, which serves dual functions to establish electrochemical sensing and colorimetric sensing based on its excellent electrocatalytic reduction of H2O2 and POD-like activity. GO-COOH played a critical role, and the electrochemically reduced ERGO-COOH facilitated electron transfer from the metal catalytic site in Fe-MOG, enhancing the performance of electrocatalytic reduction of H2O2. Additionally, GO-COOH amplified the POD-like activity of Fe-MOG, and the Fe-MOG/GO-COOH composite participated in various ROS-mediated catalytic reactions. The developed dual-mode sensor exhibited a rapid response and high sensitivity in detecting H2O2, demonstrating excellent selectivity, reproducibility, and stability. These attributes enhanced the accuracy and reliability of the detection of H2O2 released from living cells. This MOG-based nanozymatic dual-mode sensing technology offers promising prospects for enhancing the reliability of rapid detection and holds significant potential for application in pathophysiological monitoring of living cells.
研究领域:
生物医学工程
·
分析化学
·
纳米材料科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2023
·
IF 5.9
Xuan Wan,Haohao Du,Du Tuo,Xiaoman Qi,Tianyu Wang,Jingtao Wu,Guangli Li
The excessive use of gatifloxacin (GAT) can seriously pollute the environment and damage human health. Therefore, reliable detection of its concentration is essential for environmental protection and physical health. Herein, an efficient and stable voltammetric sensor based on zirconium-based metal–organic framework/carboxylated multiwalled nanotube nanocomposites (UiO-66/MWCNT-COOH) was constructed for the determination of GAT. The morphologies, microstructures, and electrochemical properties of UiO-66/MWCNT-COOH were investigated by using various microscopic, spectroscopic, and electrochemical techniques. UiO-66/MWCNT-COOH showed good electrocatalytic activity for GAT oxidation with remarkable voltammetric response signals, which was primarily attributed to the synergistic effect from UiO-66 and MWCNT-COOH. Electrochemical kinetics studies revealed that the electrocatalytic oxidation of GAT is an irreversible and diffusion-limited reaction involving two protons and two electrons. The anodic peak current of GAT is linearly correlated with GAT concentration in the range from 0.05 to 10 μM with a low detection limit of 0.0075 μM. Moreover, UiO-66/MWCNT-COOH demonstrated high selectivity, reproducibility, and repeatability as well as extraordinary long-term stability (at least 7 weeks). The proposed UiO-66/MWCNT-COOH reliably detected trace GAT in the effluent, milk, human serum, and eye drops with satisfactory recoveries. Together with its outstanding merits such as low cost, robust response, short assay time, and good sensitivity, the proposed sensor shows enormous prospects for in situ determination of multiple antibiotics.
研究领域:
环境科学
·
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 10
·13941-13947
·
IF 2.478
Liu Ying,Cao Bo,Zhang Xu,Luo Rong,Luo Chunhua,Lin Hechun,Peng Hui
Layered Co(OH) 2 has been regarded as a potential candidate for pseudocapacitor electrode material, but it is limited by its poor conductivity and low surface area. Herein, carbonated multi-walled carbon nanotubes (MWCNTs-COOH) were used to improve the conductivity of α-Co(OH) 2 nanocomposites. α-Co(OH) 2 nanoflowers were successfully grown and tangled with MWCNTs-COOH to form a randomly oriented network structure mediated by ammonia using water-methanol as co-solvent at room temperature. The capacitance performances of the obtained α-Co(OH) 2 @MWCNT-COOH composites were investigated to find that MWCNT-COOH improved the specific capacitance efficiently. Especially, in the presence of 20% in mole of MWCNT-COOH, the composite gave rise to the high specific capacitance of 1027 F/g at the current density of 2 A/g with good cycle stability, whose specific capacitance remained 78% of its original even after 5000 cycles at 30 A/g current. The large surface area and strengthening the conductivity of the composites lead to the improvement of efficiency in charge/discharge process.
研究领域:
材料科学
·
能源存储
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry B
·
2026
·
IF 6.2
Fugang Li,Qiang Li,Feng Chen,Chenxu Yan,Yongxi Zhao,Zhiqian Guo
High sensitivity and accuracy in detecting the myocardial damage biomarker, human cardiac troponin T (cTnT), is critical for the early diagnosis of acute myocardial infarction. However, conventional chemiluminescent (CL) probes suffer from instability, poor solubility, and inadequate bioavailability, which limit their clinical utility. Here, we describe a novel nanosized CL system (lucigenin@PS-COOH) for cTnT detection, wherein carboxyl polystyrene (PS-COOH) microspheres encapsulate lucigenin, significantly enhancing stability, water dispersibility, and antibody conjugation. Compared with traditional CL probes, lucigenin@PS-COOH exhibits exceptional stability, biocompatibility, and CL signal intensity. In addition, lucigenin@PS-COOH demonstrates excellent linearity with clinical data from Longhua Hospital, suggesting strong potential as a clinical assay for cTnT detection in real-world patient samples. Thus, lucigenin@PS-COOH can serve as a powerful tool for accurate cTnT detection in clinical settings and facilitate further research into the role of cTnT in disease.
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Runfeng Zhang,Yan Zhang,Hai Yu,Zongmao Lv,Jie Liu,Xiaogang Luo,Xuejing Zheng,Keyong Tang
A rationally designed MWCNT-COO-MXene/PNIPAM-PAM bilayer hydrogel actuator. • Covalent heterostructure enables rapid photothermal actuation and self-sensing. • Excellent mechanical strength and reversible biomimetic shape-morphing. • An integrated device couples NIR-driven motion with real-time resistance feedback. Stimulus-responsive hydrogels hold great potential in soft robotics, yet conventional PNIPAM hydrogels are limited by slow response speed, single functionality, and poor mechanical strength. Introducing photothermal fillers such as MXene and carbon nanotubes (CNTs) is an effective strategy to enhance their performance. However, conventional physical blending results in weak interfacial interactions, filler aggregation and limited performance enhancement. Here, we address this challenge by constructing a covalent MWCNTs-COOH@MXene heterostructure via EDC/NHS-mediated esterification, which serves as an efficient conductive and thermal network within the PNIPAM matrix and is firmly integrated with the polyacrylamide (PAM) passive layer through interfacial interpenetration. Compared with the physically blended counterpart, the covalently bonded hydrogel exhibits significantly enhanced thermal conductivity (1.49 W/(m·K)) and higher photothermal conversion efficiency (45.03%). The bilayer actuator exhibited rapid and reversible bending with a response time of 10 s, reaching a maximum bending angle of 420° under thermal stimulation and 80° under NIR light. The actuation amplitude could be controlled by adjusting the thickness ratio of the layers, temperature, and light parameters. Leveraging the efficient photothermal conversion and internal heat conduction of the MWCNTs-COOH@MXene heterostructure, the hydrogel achieved fast light-driven deformation and enabled biomimetic applications such as flower-like opening/closing, target grasping, and autonomous swimming. By integrating actuation and sensing functions, an NIR-light-controlled switch was realized that performed photomechanical actions while providing real-time state feedback through resistance monitoring. This work provides a new material platform and design strategy for high-performance soft robots and intelligent actuators with integrated functionalities. Download: Download high-res image (420KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POLYMER RESEARCH
·
2024
·Vol. 31
·期 12
·1-15
·
IF 2.6
Wang Ziyu,Shi Gege,He Yanyang,Wu Ranran,Hu Yufang,Wang Sui,Mao Jie
Annealing is a heat treatment process for materials. In this study, a conductive hydrogel was synthesized by a one-pot method using three raw materials: polyvinyl alcohol(PVA), carboxylated carbon nanotubes(Multi-Walled Carbon Nanotubes-COOH, MWCNTs-COOH) and polyethyleneimine (PEI). Based on the traditional freeze-thaw method for the preparation of PVA-based hydrogels, the annealing treatment was further added here to enhance the mechanical properties and fatigue resistance of the hydrogels. The synthesized conductive hydrogels were annealed in oven at different temperatures for a certain time, and the optimized experimental conditions and results were: the mechanical properties of the conductive hydrogel were best improved under the condition of 100 ℃-20 min, with the ultimate stress of 30.8 MPa and toughness as high as 779.58 MJ/m 3 . A high-strength, fatigue-resistant conductive hydrogel was successfully prepared, and its mechanical properties far exceeded those of other conductive hydrogels. Through a series of tests such as X-ray powder diffraction (XRD) and scanning electron microscopy (SEM), it was found that annealing promotes the orderly arrangement of PVA chains and crystallization through high temperatures, so as to enhance the mechanical properties of hydrogels. As a relatively simple and inexpensive annealing post-treatment technique, it is expected to be more widely used in improving the mechanical properties of hydrogels.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 17
·4196
·
IF 4.2
Yongzhang Xu,Xingrui Luo,Fulin Wang,Wentao Xiang,Chensheng Zhou,Weiya Huang,Kangqiang Lu,Shaoyu Li,Man Zhou,Kai Yang
The development of efficient and environmentally friendly photocatalysts is crucial for addressing global energy and environmental challenges. Perylene diimide, an organic supramolecular material, holds great potential for applications in mineralized phenol. In this study, through the integration of different mass ratios of unmodified perylenimide (PDI-NH) into the self-assembly of amino acid-substituted perylenimide (PDI-COOH), a novel supramolecular organic heterojunction (PDICOOH/PDINH) was fabricated. The ensuing investigation focuses on its visible-light mineralized phenol properties. The results show that the optimal performance is observed with a composite mass fraction of 10%, leading to complete mineralization of 5 mg/L phenol within 5 h. The reaction exhibits one-stage kinetics with rate constants 13.80 and 1.30 times higher than those of PDI-NH and PDI-COOH, respectively. SEM and TEM reveal a heterogeneous interface between PDI-NH and PDI-COOH. Photoelectrochemical and Kelvin probe characterization confirm the generation of a built-in electric field at the interface, which is 1.73 times stronger than that of PDI-COOH. The introduction of PDI-NH promotes π-π stacking of PDI-COOH, while the built-in electric field facilitates efficient charge transfer at the interface, thereby enhancing phenol decomposition. The finding demonstrates that supramolecular heterojunctions have great potential as highly effective photocatalysts for environmental remediation applications.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2012
·
IF 1.58
Xiaoqing Wang,Li Yu,Jingjing Jiao,Huina Zhang,Rui Wang,Hui Chen
A series of novel COOH-functionalized imidazolium-based surface active ionic liquids (SAILs), N-alkyl-N′-carboxymethyl imidazolium bromide ([N-C n , N′-CO 2 H-Im]Br, n = 10, 12, 14), was synthesized. Their aggregation behavior in aqueous solution was investigated by surface tension and steady-state fluorescence measurements. From surface tension data, a group of micellization parameters was obtained. Compared with 1-alkyl-3-methylimidazolium bromide ([C n mim]Br) bearing the same hydrocarbon chain, [N-C n , N′-CO 2 H-Im]Br exhibits considerably lower critical micelle concentration (cmc) and surface tension at cmc (γ cmc ), higher adsorption efficiency ( pC 20 ) and effectiveness of surface tension reduction ( π cmc ), indicating the incorporation of carboxyl group favors micelle formation. The average aggregation number (N agg ) values of [N-C n , N′-CO 2 H-Im]Br, determined by fluorescence quenching method, are slightly different from those of [C n mim]Br. The effect of temperature on the aggregation behavior of [N-C 12 , N′-CO 2 H-Im]Br was also studied. It is found that there exists a minimum cmc at nearly 38 °C, which is higher than that of [C 12 mim]Br.
研究领域:
化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）