Journal of Nanomaterials
·
2019
·
IF 2.233
Hui Zhang,Jiangying Zhu,Yanqiang Hu,Aonan Chen,Liang Zhou,Hui Gao,Yamei Liu,Shengquan Liu
A novel cellulose/TiO2/β-CD hydrogel with high photocatalytic antibacterial activity and sustained release of drug was prepared. TiO2 sol with a diameter of about 9 nm in this hydrogel was the photoantibacterial agent. β-CD can significantly enhance photoantibacterial activity and the sustained-release effect of this hydrogel. The structure and property of this hydrogel composite were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Escherichia coli and Staphylococcus aureus were selected as model bacteria to evaluate the antibacterial activity of the composite hydrogel under natural light irradiation and darkness, respectively. The in vitro release experiment used curcumin as a model drug in PBS buffer solution. The influence of β-CD on the antibacterial activity and sustained-release effect of the composite hydrogel was investigated. The results showed that the hydrogel composite presented a good photoantibacterial property, while the antibacterial activity can be neglected under the condition of no light. The complete release of curcumin from the composite was achieved after 120 h. Therefore, the hydrogel system has the characteristics of low cost and high effect, which could be used for an antibacterial sustained-release material.
研究领域:
材料科学
·
生物医学工程
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产品关联
DOI
高影响因子
SCRIPTA MATERIALIA
·
2024
·
IF 5.3
Zixing Zhen,Xuan Ge,Zhencai Li,Morten M. Smedskjaer,Wenquan Lu,Fan Yang,Jianguo Li,Qiaodan Hu
Primary ( α ) structural relaxation is known to influence the nucleation behavior in glasses and it has recently been proposed to account for the so-called classical nucleation theory “breakdown” in oxide glasses around the glass transition temperature . However, it is unclear whether secondary ( β -) relaxation, predominant at lower temperatures, also plays a role in promoting crystallization. Here, we study the correlation between crystallization kinetics and β -relaxation of three types of oxide glasses with distinct chemical bonds by subjecting the glasses to low-temperature annealing. We find that the activation energy of crystallization ( E a ) exhibits an exponential decay with increasing annealing duration for all studied glasses. Such a decrease in E a is found to be associated with the structural rearrangements in the glasses, especially showing a negative correlation with the enhanced atomistic interplays around modifying cations. Our findings thus point to a universal linkage between β -relaxation and nucleation kinetics in oxide network glasses.
研究领域:
材料科学
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凝聚态物理
·
化学
✓ 已验证
DOI
高影响因子
COLLOID AND POLYMER SCIENCE
·
2025
·
IF 2.3
Liu Yinyin,Wang Lei,Liu Guiru,Jin Hongtao,Lai Xiaojuan,Li Haibin,Chen Jiali
X-β-cyclodextrin (β-CD), a vinyl-functionalized monomer, was successfully synthesized through the chemical modification of β-CD. Subsequently, X-β-CD was co-polymerized with acrylic acid, acrylamide, and 2-acrylamido-2-methylpropane sulfonic acid via free radical copolymerization to produce a novel hydrophobic inclusion polymer—X-β-HPAM. The structure of X-β-HPAM was characterized using Fourier transform infrared spectroscopy, proton nuclear magnetic resonance spectroscopy, and scanning electron microscopy. Furthermore, its aqueous rheological properties were analyzed through rheometry. The results revealed that at shearing temperatures of 120 °C and 150 °C and a shear rate of 170 s −1 , the viscosity of a 0.4% X-β-HPAM aqueous solution gradually increased beyond a shear time of 1200 s, indicating the thickening effect of the X-β-CD monomer on the solution at elevated temperatures. Following shearing for 2 h, the residual viscosity stabilized at 62.24 mPa·s, after undergoing a shearing process for a duration of 2 h, the viscosity of a X-β-HPAM salt solution, with a mass fraction of 0.4% and dissolved in a 5% NaCl aqueous solution at a temperature of 150℃, remains consistently stable at the value of 60.04 mPa·s, demonstrating the excellent salt, temperature, and shear resistance of X-β-HPAM. Thus, β-CD-modified polyacrylamide enhances the thermal resistance and shear resistance of fracturing fluids, thereby improving recovery efficiency. Graphical abstract
研究领域:
材料科学
·
化学工程
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产品关联
DOI
高影响因子
ACS Omega
·
2020
·
IF 2.87
Bo Gao,Gengxin Wang,Bao Li,Lixin Wu
To understand the self-inclusion and the dissociation in a branched β-cyclodextrin (CD) system, we designed and synthesized a β-CD trimer in which each CD group is connected to one of bridging arms of a planar triphenylbenzene core through a CuAAC click reaction. Only one rather than two or all of the three host CDs was demonstrated to be in a self-including state in water, while no self-inclusion was observed to occur in dimethylsulfoxide (DMSO) via the characterization of 1H and NOESY NMR spectra. The configuration structures of the CD groups in the self-included state were evaluated, and the dissociation to free state in water was investigated under various conditions like heating, increased acidity, and discharging versus the addition of competitive guests. While raised temperature and increased acidity did not break the self-inclusion, two adamantane guest molecules were found to show capability in driving the equilibrium to get back to free state against the self-inclusion. The inclusion process of the added guests was believed to involve in the dissociation of the self-inclusion and the occupation of the guests in CD cavity. The results of host–guest interaction study indicated that the stable combination of guests was favorable for blocking the structural overturning of glucose toward trapping the bridging group into the cavity.
研究领域:
化学
·
分子生物学
✓ 已验证
DOI
高影响因子
DESALINATION
·
2024
·
IF 8.3
Jian Yu,Ling Zhang,Hongguang Sun,Renjie Li,Die Ling Zhao,Liguo Shen,Hongjun Lin,Yang Jiao,Yanchao Xu
The use of sacrificial layers on porous substrates has proven to be an effective approach for regulating the interfacial polymerization process and shaping the structure of polyamide (PA) nanofiltration (NF) membranes, thereby addressing the trade-off between permeability and selectivity. However, the synthesis and removal of traditional interlayer materials often require harsh chemicals, generating hazardous waste and posing environmental risks. In this study, we utilized green, non-toxic, and biodegradable β-cyclodextrin (β-CD) nanosheets as an interlayer in the interfacial polymerization process. These nanosheets were subsequently dissolved in water to create crumpled polyamide nanofiltration membranes, avoiding the use of toxic chemicals and significantly reducing environmental impact. With an optimal β-CD loading of 1.0 mg/cm 2 , the resulting membrane exhibited a remarkable water flux of 13.4 LMH/bar, reflecting a 330 % improvement over the reference membrane, along with a 97.9 % Na₂SO₄ rejection. This performance enhancement is linked to enhanced surface hydrophilicity, a higher surface charge density, and a thinner PA layer with an expanded surface area. The membrane also exhibited excellent antifouling properties and long-term separation performance. This innovative, eco-friendly approach represents a significant advancement in membrane technology, providing a sustainable solution for enhanced nanofiltration membrane performance in water treatment applications.
研究领域:
材料科学
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环境科学
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水处理技术
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产品关联
DOI
高影响因子
International Journal of Environmental Research and Public Health
·
2013
·Vol. 10
·期 7
·2688-2698
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IF 1.998
Wenbin Wang,Liqiang Liu,Liguang Xu,Wei Ma,Hua Kuang,Chuanlai Xu
β-Lactamase residues in milk represent a public health risk. The cylinder plate detection method, which is based on bacterial growth, is laborious and time consuming. In this study, 15 monoclonal antibodies (mAbs) were selected against Temoneira (TEM) 1 β-lactamase. A sandwich enzyme-linked immunosorbent assay (ELISA) based on an optimum mAb pair was developed and validated for the detection of β-lactamase. The limit of detection and linear dynamic range of the method were 4.17 ng/mL and 5.5–100 ng/mL, respectively. β-Lactamase recovery in pure milk was 96.82–103.13%. The intra- and inter-assay coefficients of variation were 6.21–7.38% and 12.96–13.74%, respectively. Our developed sandwich ELISA can be used as a rapid detection method of β-lactamase in milk.
研究领域:
食品科学
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免疫学
·
公共卫生
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
·
2019
·Vol. 55
·期 5
·1900-1908
·
IF 2.281
Min Pang,Xiuxiu Wang,Lili Cao,Zhaojuan Shi,Zheng Lei,Shaotong Jiang
Summary Oleogels of β-sitosterol (Sit) and beeswax (BW) were combined at varying ratios (w/w) and added to sunflower oil (SFO) at concentrations of 10 g per 100 g and 20 g per 100 g oil to prepare oleogels (Sit/BW/SFO). Structural and thermal properties were characterised and results showed that the hardness and enthalpy of oleogels were affected by the amount of β-sitosterol and beeswax in the oleogelator combination (Sit/BW, w/w). Oleogels with beeswax as the only oleogelator (Sit0/BW10) had the highest hardness and maximum enthalpy change. Gel network form was influenced by the crystalline behaviour of the oleogelator, and Sit0/BW10-oleogel was densely packed, spherical and white while Sit10/BW0-oleogel displayed a needle shape. X-ray diffraction patterns showed that the oleogel width of the crystals and D- spacing increased with increasing amounts of β-sitosterol and the FTIR spectra revealed that oleogels formed via non-covalent bonding and may be stabilised with physical entanglements.
研究领域:
食品科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
CHIRALITY
·
2013
·Vol. 25
·期 10
·656-662
·
IF 1.894
Yangmin Ma,Hao Wu,Jin Zhang,Yanchao Li
A series of single isomers tetrahydro- β -carboline diketopiperazines were stereoselectively synthesized starting from l -tryptophan methyl ester hydrochloride and six aldehydes through a four-step reaction including Pictet-Spengler reaction, crystallization-induced asymmetric transformations (CIAT), Schotten-Baumann reaction, and intramolecular ester amidation. The chemical structures were characterized by nuclear magnetic resonance (NMR) and elemental analysis, among which two compounds were determined by x-ray single crystal diffraction. Moreover, antimicrobial activities of all the compounds were also tested. Chirality 25:656–662, 2013 . © 2013 Wiley Periodicals, Inc.
研究领域:
有机化学
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药物化学
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微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
·
2018
·
IF 5.158
Parbeen Singh,Xiaohong Ren,Tao Guo,Li Wu,Shailendra Shakya,Yaping He,Caifen Wang,Abi Maharjan,Vikramjeet Singh,Jiwen Zhang
Cyclodextrins nanosponges (CD-NSPs) are highly microporous crosslinked polymers with potential applications in the delivery of small and macro-molecular therapeutic agents. Despite the potent host-guest inclusion property, their inherent lack of cellular binding ability has limited applications in drug delivery. Herein, we functionalized the surface of β-cyclodextrin nanosponge (β-CD-NSP) with cholesterol, which is endogenous physiological molecules, widely distributed in all cells, and responsible for cell interactions and protein binding. The surface grafting of synthesized β-CD-NSP was confirmed with spectroscopic, microscopic, thermogravimetric, and chromatographic techniques. Moreover, β-CD-NSP was found to be safe in cytotoxicity assay. Doxorubicin (Dox) was selected as a model drug for drug adsorption study of cholesterol hydrogen succinate (CHS) grafted β-CD-NSP. The cellular uptake of NSP was found to be enhanced after CHS modification confirmed by confocal laser scanning microscopy (CLSM). Thus, proposed CHS modified β-CD-NSP system could be used as a site-specific drug delivery carrier.
研究领域:
药剂学
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生物材料
·
医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2022
·Vol. 51
·期 2
·522-531
·
IF 2.047
Zheng Jie,Chen Jiali,Tang Yu,Shen Kaiyuan,Xiang Yujie,Shen Lanxian,Ge Wen,Yang Peizhi,Deng Shukang
In this study, β -Zn 4 Sb 3 was prepared using the Zn-NaCl mixed-flux method based on the stoichiometric ratio of Zn/Sb/NaCl = (4− x ):3:(7+ x ) ( x = 0, 0.1, 0.2, 0.3). X-ray diffraction results showed that all samples were hexagonal rhombic crystal structures with the space group \(R\overline{3}c\) . A second phase of ZnSb was detected in the samples with x = 0.2 and x = 0.3. In addition, the crystal-cell volume and lattice parameter of all samples increased for the larger ion radius of Na + than Zn 2+ . The transmission electron microscopy image and corresponding area electron diffraction pattern demonstrated that the prepared samples had a complete crystal structure. All samples had hole conduction and exhibited p-type conduction behavior. The carrier concentration of the material increased with increased Na content and decreased Zn, ranging from 8.89 × 10 19 cm −3 to 17.82 × 10 19 cm −3 . Moreover, the thermal conductivity ( κ ) of x = 0–0.2 samples decreased with increased Na content; however, the sample with x = 0.3 had a higher κ owing to the appearance of a ZnSb phase. Thermogravimetric differential thermal analysis showed that no weight loss occurred below the melting point. Eventually, the sample with the nominal composition of β- Zn 3.8 Sb 3 NaCl 7.2 achieved a ZT value of 1.43 at 690 K.
研究领域:
材料科学
·
物理学
✓ 已验证
产品关联
DOI
高影响因子
Arabian Journal of Chemistry
·
2023
·
IF 6
Haijun Cheng,Min Liang,Suyi Dai,Xianrui Lu,Qilin Huang,Fang Lai,Li Ma,Weiguang Li,Xiongmin Liu
α-Pinene, β-pinene and turpentine are renewable resources that are widely used in fine chemicals, fuels and other applications, and the safety of their production, transport and use should be considered. In this work, the characteristics and hazardous of the oxidation process of α-pinene, β-pinene and turpentine were investigated by using a novel mini closed pressure vessel testing system (MCPVT). The oxidation products were resolved by gas chromatography-mass spectrometry (GC–MS). The results showed that α-pinene, β-pinene and turpentine were stable under nitrogen atmosphere and very active chemically under oxygen atmosphere. The activation energies ( E a ) of α-pinene, β-pinene and turpentine were calculated to be 78.87, 109.69 and 98.82 kJ/mol, respectively, using pressure–time (P-t) curves. So, the reaction activity sequence was α-pinene > turpentine > β-pinene. The peroxide concentrations of α-pinene (363 K), β-pinene (358 K) and turpentine (363 K) could reach 81.94, 84.70 and 75.76 mmol/kg, respectively, at relatively low temperatures. 0.6 g of α-pinene exploded at a system temperature of 369 K and an oxygen pressure of 1.23 MPa. 0.6 g of β-pinene also exploded at a system temperature of 373 K and an oxygen pressure of 1.27 MPa. 0.4 g of turpentine experienced thermal runaway at a system temperature of 384 K and an oxygen pressure of 0.81 MPa. The major oxidation products of α-pinene are α-campholenaldehyde, laevo-pinocarveol, verbenol, verbenone, bicyclo (3.1.1)heptane-2, 3-diol, 2, 6, 6-trimethyl, 2-cyclohexen-1-ol, 2-methyl-5-(1-methylethenyl)-, (1R,5R)-rel-, cyclobutaneacetic acid, 3-acetyl-2, 2-dimethyl, myrtenol and myrtenal. The major thermal runaway products are water, ethanol, acetone, acetic acid, 2-pentanone, propyl acetate, toluene, cymene and methylacetophenone. The major oxidation products of β-pinene are nopinone, laevo-pinocarveol, pinocarvone, myrtenol, myrtenal and perillyl alcohol. The major thermal runaway products are water, ethanol, acetone, n-ethyl propanoate, toluene, butyl acetate, cymene, apocamphor, nopinone, bornyl formate, methylacetophenone and dihydronopol. The oxidation products and thermal runaway products of pinene were significantly different. Possible reaction pathways for α-pinene and β-pinene are proposed.
研究领域:
化学工程
·
安全科学
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产品关联
DOI
高影响因子
POLYMER SCIENCE SERIES A
·
2021
·Vol. 63
·期 2
·143-153
·
IF 1.206
Qiuyue Guo,Chen Yuying,Li Xin,Liu Jun,Gu Qintian,Hu Jian,Jiang Yan,Zhang Hongwen,Liu Hongbo
Abstract In this paper, partly esterified β-cyclodextrin derivative had been synthesized by esterification of β-cyclodextrin and maleic anhydride. Then, it is amidated by diethanolamine. β-Cyclodextrin copolymer had been prepared from amidated β-cyclodextrin derivative, cholic acid and epichlorohydrin in sodium hydroxide aqueous solution. β-Cyclodextrin hydrogel had been prepared through radical polymerization of β-cyclodextrin copolymer, N -isopropylacrylamide and acrylic acid. The structures, compositions and morphology of the hydrogel were characterized by infrared spectroscopy, nuclear magnetic resonance, differential scanning calorimetry and field-emission scanning electron microscope. Its properties were tested and analyzed by ultraviolet spectroscopy, thermogravimetric analysis and swelling experiments. The results show that the β-cyclodextrin hydrogel owns sustained release performance, temperature and pH sensitivities.
研究领域:
材料科学
·
化学工程
·
生物医药
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）