WATER SCIENCE AND TECHNOLOGY
·
2015
·Vol. 73
·期 2
·260-266
·
IF 1.106
Zha F. G.,Yao D. X.,Hu Y. B.,Gao L. M.,Wang X. M.
The landfill leachate treated by sonication in presence of Fe 2+ (US/Fe 2+ ) and then by photo-Fenton achieved the highest total organic carbon (TOC) removal efficiency among the screened processes. The lower initial pH, dosage of Fe 2+ and initial concentration of leachate were helpful in raising TOC removal efficiency of leachate by US/Fe 2+ . The optimal conditions for the US-photo-Fenton process were as follows: initial pH at 3.0, [H 2 O 2 ]/[TOC 0 ] at 2, [H 2 O 2 ]/[Fe 2+ ] at 5 and initial concentration of landfill leachate at 600 mg/L. The removal efficiency of TOC, chemical oxygen demand (COD) and 5-day biochemical oxygen demand (BOD 5 ) were 68.3, 79.6 and 58.2%, while the BOD 5 /COD rose from 0.20 to 0.43 at optimum condition. Based on gas chromatography–mass spectrometry (GC-MS) results, 36 of a total of 56 pollutants were completely degraded by US-photo-Fenton treatment.
研究领域:
环境工程
·
水处理技术
·
高级氧化过程
·
污染控制化学
·
环境化学
✓ 已验证
DOI
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2021
·
IF 7.963
Ying Pan,Pui-Ying Leung,Yuan-Yue Li,Juan Chen,R.Y.C. Kong,Nora F.Y. Tam
Chemical and biological methods have been employed to remedy polybrominated diphenyl ether contamination, but the removal of decabromodiphenyl ether (BDE-209) by either method still has limitations. The present study aims to evaluate the combined effect of nanoscale zero-valent iron (nZVI) (from 0.1 to 10%) reduction and microbial debromination on BDE-209 removal in mangrove sediments under an anaerobic condition. During the 12-months incubation, nZVI significantly enhanced BDE-209 removal, with 17.03% to 41.99% reduction in sterilized sediments. The reduction was even higher in non-sterilized sediments with living indigenous microorganisms, achieving 15.80%, 33.50%, 55.83% and 66.95% removal of BDE-209 at 0 (control without nZVI), 0.1%, 1% and 10% nZVI, respectively. In control sterilized sediments, no debromination was found, and debromination occurred according to spiked levels of nZVI, with BDE-153 being the dominant congener. The concentrations of debrominated congeners in non-sterilized sediments also increased with nZVI levels, but were significantly higher than the respective sterilized sediment. The relative proportions of different debrominated congeners in non-sterilized sediments depended on nZVI levels, with BDE-99 being the dominant congener in low nZVI amended sediments but shifted to BDE-153 under high nZVI. Higher concentrations of ferrous iron (Fe 2+ ) were detected in both sterilized and non-sterilized sediments spiked with more nZVI, and their concentrations significantly correlated with BDE-209 removal. Growth of total bacteria in sediments with 1% and 10% nZVI was inhibited within first two months, but their numbers resumed to that in the control at the end of 12 months. The present study demonstrates the synergy between chemical and microbiological methods, and a combination of nZVI and indigenous microorganisms could be an efficient and feasible mean to remedy BDE-209 in contaminated sediments.
研究领域:
环境科学
·
微生物学
·
化学
✓ 已验证
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2019
·
IF 6.97
Chao Yang,Zhenyang Xie,Hongping Zhang,Hua Li,Yanhua Cai,Jinhu Wang,Jiayan Du,Haili Yu,Yi He
The traditional nanozymes have low atom/ion utilization efficiency and are easily influenced by the size, morphology, as well as surface composition of nanomaterials. Herein, we report a template-free and valid approach to prepare a ferrous ion (Fe2+) anchored onto the surface of the MoO3 nanosheet (Fe2+/MoO3) through coordination interaction between Fe2+ and hydroxyl groups of MoO3. The resulting Fe2+/MoO3 shows the peroxidase-like activity, and it can be utilized for catalytic decomposition of hydrogen peroxide (H2O2) to generate hydroxyl radicals (•OH) that oxidize various chromogenic substrates, generating distinct color change and strong ultraviolet–visible absorption. The Fe2+/MoO3 peroxidase mimic exhibits a good thermal stability and works well at a high reaction temperature (95 °C) and has higher affinity for substrates than for natural horseradish peroxidase. Theoretical calculation results imply that the strong electrostatic field from the polarization charges between Fe2+ and the MoO3 nanosheet improves the reaction activity, which boosts the generation of •OH from H2O2. Using the Fe2+/MoO3 peroxidase mimic-involved chromogenic system, we construct visual colorimetric assays for H2O2 and triacetone triperoxide (TATP) explosives, which realize the visual detection of H2O2 and TATP at concentrations of 40 and 60 μM, respectively.
研究领域:
材料科学
·
分析化学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
MINERALS ENGINEERING
·
2022
·
IF 5.479
Haiping Zhao,Xiaopeng Niu,Bingxu Dong,Xianbing Jia,Renman Ruan
This work aims to establish the quantitative relationship between the surface oxidation state of pyrite and flotation performance. In this paper, an efficient method was proposed to prepare pyrite with different oxidation degrees. Flotation tests show that the floatability of pyrite decreased with prolonging the oxidation time. Tof-SIMS results reveal that the main component on the oxidized pyrite surface is Fe hydroxides or oxides. XPS analysis confirms that Fe(OH) 2 and FeOOH are the main formula of Fe species, and the ratio of Fe 2+ /Total Fe agrees well with the floatability of pyrite with different oxidation degrees, which can be taken as an index to develop the flotation performance of pyrite. DFT simulation calculation further demonstrates the reliability of Fe(OH) 2 as the active site. This study provides essential surface chemistry evidence for correlating the surface species with the floatability of pyrite with different oxidation states through quantitative analysis of various intermediate products.
研究领域:
矿物加工
·
表面化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Environmental Science and Technology
·
2024
·
IF 3
Cui Y. P.,Huang Q.,Cao J. G.,Dong W.,Cui X. X.,Lu Y.,Li Y. J.,Huang Z. Q.
Fe 0 -based heterogeneous Fenton process has been increasingly developed for organic pollutants removal. However, the reaction activity of Fe 0 catalyst is easily weakened due to the formation of dense oxide layer or the precipitation of iron hydroxides on the surface. Herein, the effect and mechanism of magnetic field (MF), visible light (Vis), nitrilotriacetic acid (NTA) and inorganic salt ions on the Fe dissolution and dimethyl phthalate (DMP) degradation in the Fe 0 /H 2 O 2 system were investigated. The results showed that the magnetic field (100 mT), NTA and inorganic salt ions effectively enhanced the dissolution of Fe from the surface of iron filings, and visible light significantly accelerated the Fe 3+ /Fe 2+ cycle in the aqueous phase, which promoted the decomposition of H 2 O 2 by Fe 2+ to generate •OH and further enhanced the degradation of DMP. DMP was nearly completely degraded within 60 min in the pH range of 3.0–9.0, indicating the MF/Vis/NTA/Fe 0 /H 2 O 2 system effectively broadened the pH range of Fenton-like system. The iron sand column tests proved that the MF/solar/NTA/Fe 0 /H 2 O 2 system was effective for the treatment of waste leachate reverse osmosis concentrate as a typical actual high-salt wastewater, in which the removal rates of chemical oxygen demand and humic acid reached 84.5 and 90.6%, and the chromaticity was almost completely removed. Generally, the activation mechanism of Fe 0 -based heterogeneous photo-Fenton system was set up and an effective method for organic pollutant removal and high-salt wastewater treatment was provided.
研究领域:
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Qian Wang,Jingfeng Gao,Hao Chen,Ying Liu,Xiaoyu Fu,Jiawen An,Hanyi Wang,Yuxuan Wang
Antibiotic resistance has turned into a focus of universal public health concern. Wastewater treatment plants are considered as reservoirs of antibiotic resistant bacteria (ARB) and antibiotic resistant genes (ARGs), which can be transmitted to the environment. In this research, an effective method for inactivating Escherichia coli DH5α ( E. coli DH5α) carrying resistance genes was developed utilizing dual oxidant system of peroxymonosulfate (PMS) and sodium percarbonate (SPC) in the presence of ferrous ions (Fe(II)). The results indicated that E. coli DH5α could be inactivated 6.36 log under the conditions of 0.50 mM PMS, 0.50 mM SPC and 0.50 mM Fe(II) after 30 min. Besides, the removal of different types of ARB and pollutants could also be achieved by Fe(II)/PMS/SPC system. The quenching experiments and EPR analysis demonstrated that reactive species (•OH, SO 4 •− , O 2 •− , 1 O 2 and CO 3 •− ) involved in the inactivation of E. coli DH5α. Bacterial damage mechanisms were systematically studied in terms of cell structure and morphology, enzyme activity, malondialdehyde and intracellular reactive oxygen species levels. The inactivation of E. coli DH5α in complex water matrix (including coexisting of anions and natural organic matter) and real wastewater was inhibited. The abundance of intracellular ARGs decreased by 1.15 log, whereas extracellular ARGs increased by 0.32 log. This research supplied a prospective approach for inhibiting the dissemination of antibiotic resistance.
研究领域:
环境科学
·
微生物学
·
水处理
·
公共卫生
✓ 已验证
产品关联
DOI
高影响因子
Discover Oncology
·
2024
·Vol. 15
·期 1
·1-11
·
IF 2.8
Jiang Xinru,Li Hongdan,Liu Yang
Objective Hepatocellular carcinoma (HCC) is one cancer with high death rates. Nowadays, there are no effective drugs to treat it. Cyclovirobuxine D (CVB-D) is the primary ingredient of the traditional Chinese medicine (TCM) Buxus microphylla . Here, we try to explore the impacts of CVB-D on human HCC cells and explain the potential mechanisms. Methods HepG2 and Huh-7 cells were used for our experiments. The cell viability and half inhibitory concentration (IC50) were detected by MTT assays. The apoptosis ratio was examined by Annexin V-FITC/7AAD staining and flow cytometry (FCM). The Fe 2+ content was examined by ferrous ion content assays. The malondialdehyde (MDA) content was evaluated by lipid peroxidation MDA assays. The reactive oxygen species (ROS) level was examined by the DCFH-DA probe. The expression of apoptotic markers (Bax and Bcl-2) and ferroptosis-related proteins (GPX4 and FSP1) was detected by western blotting. The in vivo curative effect of CVB was explored using xenograft models established in C-NKG mice. Results The cell viability could be inhibited by CVB-D in HepG2 and Huh-7 cells. The IC50 value of CVB-D on HepG2 and Huh-7 cells are 91.19 and 96.29 µM at 48 h, and 65.60 and 72.80 µM at 72 h. FCM showed that the apoptosis rate was increased by CVB-D in HepG2 and Huh-7 cells. Next, ferrous ion content assays showed that the level of Fe 2+ was increased by CVB-D in HepG2 and Huh-7 cells. Then, we found the level of MDA and ROS was increased by CVB-D. And the Fe 2+ promotion by CVB-D could be reversed by Fer-1. Additionally, western blotting assays showed that the expression of GPX4 and FSP1 was inhibited by CVB-D in HepG2 and Huh-7 cells. Moreover, in vivo, CVB-D displayed excellent anticancer effects in HCC tumor-bearing C-NKG mice. Conclusion CVB-D suppresses the growth in HCC cells through ferroptosis.
研究领域:
肿瘤学
·
药理学
·
细胞生物学
·
中医药
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOTECHNOLOGY LETTERS
·
2020
·Vol. 42
·期 3
·445-451
·
IF 1.977
Zhang Lei,Xu Danyu,Kong Deyong,Ji Min,Shan Lianbin,Zhao Yongjiao
Objectives To investigate the effect of zero-valent iron and copper (Fe/Cu) micro-electrolysis on dark fermentative hydrogen production from glucose by a mixed bacterial consortium and the possible mechanisms of increasing hydrogen yield. Results Compared to zero-valent iron and activated carbon (Fe/C) micro-electrolysis, Fe/Cu micro-electrolysis could increase hydrogen yield by 32.2%, hydrogen production potential by 27.1%, and the maximum hydrogen production rate by 62.0%. Meanwhile, the number of ferrous ions released into the liquid phase with Fe/Cu micro-electrolysis was about 27.0% greater than that released by Fe/C micro-electrolysis, because the dispersion of copper on the surface of iron could markedly improve electrochemical corrosion activity. Metabolic analysis revealed that Fe/C micro-electrolysis promoted acetate formation, which may have been responsible for the observed improvement in fermentative hydrogen production. Further investigation indicated that Fe/Cu micro-electrolysis increased the activity of hydrogenases and stimulated the expression of the [FeFe]-hydrogenase gene. Conclusion Fe/Cu micro-electrolysis is better than Fe/C micro-electrolysis or Fe corrosion alone for dark fermentative hydrogen production.
研究领域:
环境工程
·
微生物学
·
生物技术
✓ 已验证
DOI
PubMed
高影响因子
Materials Today Chemistry
·
2024
·
IF 6.7
Bing-Bing Shou,Ting-Ting Li,Xian-Jin Hu,Guo-Hua Liu,Hai-Tao Ren,Jia-Horng Lin,Jingwei Xie,Li-Yan Liu,Ching-Wen Lou
Bacterial infections result in serious impacts on human health. Non-toxic, potent, and flexible antimicrobial particles loaded onto nonwoven materials offer a promising solution. Metallic antimicrobial particles have achieved significant attention and application; however, common materials such as silver and copper exhibit potential toxicity and typically employ a singular antimicrobial mechanism. This limitation can diminish their effectiveness over the service cycle. In our research gallium (Ga), known for its activity and versatile antimicrobial mechanisms, was employed with ferrous ions (Fe 2+ ), which offer broad-spectrum antimicrobial properties and lower potential toxicity compared to silver and copper. Through spontaneous substitution reaction. Ga and Fe 2+ can generate Ga–Fe alloys and various antimicrobial particles. In this study, we developed antimicrobial nonwovens by loading them with multiple types of metal antimicrobial particles through a simple soaking and surface treatment process. The multifaceted antimicrobial mechanisms introduced by these multiple particles provide the nonwoven materials with exceptional antimicrobial performance, achieving an effectiveness of up to 99.99 % against Escherichia coli and Staphylococcus aureus . The feasibility of the substitution reaction between Ga and Fe 2+ was thoroughly verified through theoretical calculations, X-ray photoelectron spectroscopy (XPS) characterization, and experimental observations. This research offers valuable insights for advancing and exploring antimicrobial nonwoven materials.
研究领域:
材料科学
·
生物技术
·
微生物学
·
化学工程
✓ 已验证
DOI
高影响因子
Nanoscale Research Letters
·
2021
·Vol. 16
·期 1
·1-11
·
IF 4.703
Li Zihaoran,Wu Xinghan,Wang Wenyu,Gai Chengcheng,Zhang Weifen,Li Wentong,Ding Dejun
Suppression of tumor development by inducing ferroptosis may provide a potential remedy for triple-negative breast cancer, which is sensitive to intracellular oxidative imbalance. Recently, artemisinin (ART) and its derivatives have been investigated as potential anticancer agents for the treatment of highly aggressive cancers via the induction of ferroptosis by iron-mediated cleavage of the endoperoxide bridge. Owing to its poor water solubility and limited intracellular iron content, it is challenging for further application in antitumor therapy. Herein, we developed ferrous-supply nano-carrier for ART based on tannic acid (TA) and ferrous ion (Fe(II)) coated on the zeolitic imidazolate framework-8 (ZIF) with ART encapsulated (TA-Fe/ART@ZIF) via coordination-driven self-assembly. Drug release experiments showed that ART was not nearly released in pH 7.4, while 59% ART was released in pH 5.0 after 10 h, demonstrating the excellent pH-triggered release. Meanwhile, a high level of intracellular ROS and MDA, accompanied with decreasing GSH and GPX4, displayed a newly developed nano-drug system displayed markedly enhanced ferroptosis. Compared with monotherapy, in vitro and vivo tumor inhibition experiments demonstrated higher efficiency of tumor suppression of TA-Fe/ART@ZIF. This work provides a novel approach to enhance the potency of ferroptotic nano-medicine and new directions for TBNC therapy.
研究领域:
肿瘤学
·
药学
·
纳米技术
·
癌症治疗
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Nano Materials
·
2022
·
IF 6.14
Jialing Zhou,Yumeng Zhang,Yaqian Du,Ruoxi Zhao,Shikai Liu,Wenting Li,Qingqing Wang,Piaoping Yang
The Fenton reaction has been widely utilized in tumor therapy and ferroptosis immunity in recent years. Therefore, the detection of hydrogen peroxide (H2O2), hydroxyl radicals (•OH), and iron(II) (Fe2+) in serum is urgently in need. A multifunctional combined carbon–CdTe quantum dots (C-CdTeQDs) probe is first established for the quick succession determination of H2O2 and Fe2+ in goat serum and human urine based on the fluorescence and colorimetric method. The double-emission fluorescence detection is performed by breaking the thioglycolic acid bond on the surface of CdTeQDs by H2O2 to quench the fluorescence at 594 nm. After the condition optimization, the fluorescence intensity is linearly related to H2O2 concentration, with a limit of detection of 58 nM. The colorimetric detection of •OH and Fe2+ concentrations is then continued by the Fenton reaction and the complexation reaction. Among them, the detection range of •OH is 0.01–0.1 μM with the limit of detection of 8 nM. Several advantages such as versatility, convenience, high selectivity, and sensitivity of the C-CdTeQDs probe indicated that it has great potential for the determination of H2O2 and Fe2+ in serum.
研究领域:
分析化学
·
生物化学
·
纳米技术
·
医学诊断
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2018
·Vol. 410
·期 28
·7373-7384
·
IF 3.307
Shi Yi,Peng Jun,Meng Xiaoyan,Huang Tao,Zhang Jingyi,He Hua
Here, one kind of hydrophilic hydroxypropyl β-cyclodextrin cross-linked polymer (HP-CDP) was prepared and used to establish a “turn-on” fluorescent probe for selective determination of captopril in biological samples. The HP-CDP has been synthesized in one step by cross-linking (2-hydroxypropyl)-β-cyclodextrin (HP-β-CD) with a rigid aromatic group linker tetrafluoroterephthalonitrile (TFT), and the synthesis parameters of HP-CDP were optimized with water solubility, yield, and adsorption capacity as indicators. When it was used as a luminescent material, we have found an interesting phenomenon that the fluorescence emission of HP-CDP was quenched after forming a coordination compound with ferric ions, and then recovered after adding a certain concentration of captopril, since captopril can reduce the ferric iron to ferrous ions and cause ligand replacement. Based on this observation, a novel turn-on fluorescent method was developed for the determination of captopril. The method exhibited good linearity in the range of 9.2 × 10 −7 to 4.6 × 10 −4 M ( R 2 = 0.9982) and a low detection limit of 1.8 × 10 −7 M at optimum HP-CDP concentration, ferric ion concentration, pH, and incubation time. Moreover, interference experiments demonstrated that this fluorescence sensor had excellent selectivity that can commendably resist the interference from potential foreign substances. The proposed method has been successfully applied to determine captopril in human urine samples and may provide outstanding application potential in the future development of sensors. In addition, it is believed that HP-CDP also has a wide range of applications, for example, as a solubilizer, pollutant adsorbent, or drug carrier.
ᅟ
研究领域:
分析化学
·
材料科学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）