Biomolecules
·
2022
·Vol. 12
·期 11
·1601
·
IF 6.064
Weiyan Quan,Puwang Li,Jinsong Wei,Yuwei Jiang,Yingye Liang,Weilin Zhang,Qizhou Chen,Kefeng Wu,Hui Luo,Qianqian Ouyang
Creation of bio-multifunctional wound dressings with potent hemostatic, antibacterial, anti-inflammatory, and angiogenesis features for bolstering the healing of full-thickness wounds is sought after for clinical applications. We created bio-multifunctional composite sponges by coupling alginate and chitosan withSargassum pallidumpolysaccharides through electrostatic interactions, calcium ion (Ca2+) crosslinking, and lyophilization. Alginate/chitosan (AC) sponges with different concentrations ofSargassum pallidumpolysaccharides were obtained and termed AC, ACS—1%, ACS—2.5%, and ACS—5%. ACS—1% and ACS—2.5% sponges exhibited uniform porosity, high water vapor transmission rate, high water absorption, as well as good hemostatic and antibacterial abilities. ACS—2.5% sponges facilitated wound closure and promoted angiogenesis and re-epithelialization in the dermis. These data suggest that ACS sponges containing a certain amount ofSargassum pallidumpolysaccharides could be employed for treatment of full-thickness skin wounds.Keywords:Sargassum pallidumpolysaccharides;bio-multifunctional;composite sponges;wound healing;alginate;chitosan
研究领域:
生物材料学
·
医学工程
·
伤口护理
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Zhenzhen Li,Yu Su,Jiayin Fang,Ye Lu,Xia Xiao,Biwen Yang,Haolin Chen,Binggang Ye,Zhouyi Guo,Zhiming Liu
We report a groundbreaking textile modification strategy utilizing fluorescent whitening carbon dots (FW-CDs) to simultaneously achieve multifunctional performance while maintaining fabric comfort. Through controlled hydrothermal synthesis of traditional VBL precursor, bright blue-emitting FW-CDs with extremely high brightness and nanoscale uniformity were successfully fabricated. The FW-CDs, forming hydrogen bonds with cotton, exhibit a superior binding affinity, enhancing the whitening performance significantly with a whiteness index of 94.3, compared to 92.6 for VBL controls. Moreover, they endow the fabric with remarkable durability, ensuring 95.25% whiteness retention after 5 accelerated laundering cycles, and excellent UV stability, maintaining 97.61% of the initial whiteness after 96 h of UV exposure. The engineered textile system also exhibited remarkable multifunctionality: FW-CDs also have excellent antibacterial, antioxidant, and UV-shielding properties. At a concentration of 0.5% (o.w.f), the antibacterial rate against Escherichia coli and Staphylococcus aureus exceeds 99%. The DPPH radical scavenging rate is 58.6%, and the UV-protection factor (UPF) increases from 4.1 to 7.6. Moreover, the modification barely affects cotton’s original properties. This first demonstration of CDs integrating four functionalities (whitening/antibacterial/antioxidant/UV-blocking) with durability positions this technology as an industrially feasible nanomaterial solution within the textile industry.
研究领域:
纺织科学
·
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
·
2025
·
IF 8.9
Yanyun Li,Tiancheng Wang,Junying Zhang,Jue Cheng,Qingsong Lian
In recent years, thermal management technology based on phase change materials (PCMs) has provided a new solution for the development of wearable thermal management systems. However, because the high enthalpy value, flexibility, and multi-functional integration of PCMs are mutually restricted, most of the reported wearable thermal management materials cannot achieve the synergic development of flexibility at room temperature, multi-functionality, and heat storage capacity of PCMs. In this paper, a new type of flexible PCMs was prepared by using bio-based modified eugenol epoxy resin and lauric acid. It is worth noting that due to the flexibility of the epoxy network itself and its excellent compatibility with La, the final PCMs exhibit high encapsulation rate (80 wt%) and high enthalpy value (163.3 J/g). Finally, the PCMs were combined with graphene paper to prepare a composite film, which has excellent thermal conductivity (3.28 Wm −1 K −1 ), electromagnetic interference shielding property (42 dB), solar-thermal (86.7 %, 1000 W/m 2 ), and electro-thermal (89.3 %, 3.0 V) conversion and storage capabilities. Besides, the composite film not only has good flexibility at room temperature, but also shows excellent multi-mode shape memory performances. Last but not least, the composite film has great application potential in the field of wearable thermal therapy equipment.
研究领域:
材料科学
·
热能工程
·
柔性电子
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Lisheng Wu,Ling Wang,Zheng Guo,Junchen Luo,Huaiguo Xue,Jiefeng Gao
Superhydrophobic coatings have wide applications in many fields. However, superhydrophobic and smart coatings with multifunctionality and their applications in flexible sensing electronics are seldom reported. In this work, durable, superhydrophobic, and anticorrosive coatings with excellent Joule heating and electromagnetic interference (EMI) shielding performance are prepared on the basis of Ag precursor reduction and synchronous nonsolvent induced phase separation. Silver nanoparticles (AgNPs) coated with the copolymer (polystyrene-block-poly(ethylene-co-butylene)-block-polystyrene: SEBS) are uniformly distributed on the target substrate, forming mechanically durable conductive network. SEBS could not only endow the surface coating with superhydrophobicity but also improve the interaction among individual Ag nanoparticles and the interfacial adhesion between AgNPs and the substrate. The multifunctional coating possesses excellent anticorrosive, self-cleaning, and deicing properties. The high conductivity endows the coatings with excellent Joule heating and EMI shielding performance. The multifunctional coating can be applied to a variety of different substrates with outstanding surface stability and reliability. The conductivity for the smart coating can reach as high as 107 S/cm with the EMI shielding effectiveness up to 37.8 dB. At a low applied voltage of 1 V, the conductive fabric can be heated up to over 80 °C in 60 s and displays good recyclability during dozens of heating and cooling cycles. The Joule heating-induced temperature increase could be used for efficient surface deicing. When used for the flexible and wearable strain sensors, the multifunctional coating has a very low strain detection limit of 0.5% and large sensitivity (with the gauge factor as high as 1075) and excellent repeatability. In addition, it can be used for precisely monitoring different body motions, including both large and subtle joint movement.
研究领域:
材料科学
·
电子工程
·
表面化学
✓ 已验证
DOI
PubMed
高影响因子
CHINESE JOURNAL OF CHEMISTRY
·
2021
·Vol. 39
·期 11
·3085-3092
·
IF 6
Yaqian Cai,Jiachuan Shi,Fangzhe Liu,Haichao Li,Xinya Man,Shuang Guan
Main observation and conclusion Natural biopolymer-based hydrogels have been extensively studied in recent years due to their excellent biocompatibility. However, the preparation of multi-functional and tough natural biopolymer-based hydrogels is still a challenging problem. Herein, a natural biopolymer-based hydrogel is prepared using gelatin and carboxymethyl chitosan (CMCS) through a one-step soaking method. The prepared hydrogel without any synthetic polymers and crosslinking agents has a fully physical crosslinking structure. Due to the hydrophobic interaction brought by the Hofmeister effect, the mechanical properties of soaked hydrogels (tensile stress and strain can reach 3.77 MPa and 1082%) are superior to conventional protein hydrogels. In addition, the prepared gelatin/carboxymethyl chitosan (Gel/CMCS) hydrogels exhibit a variety of appealing properties, including good shape memory, fatigue resistance, electrical conductivity, water retention, drug releasing, antibacterial property, and recyclability. This strategy opens up a new horizon to fabricate hydrogels with excellent mechanical properties and multiple functions, which can extend their applications in the biomedicine area and other related fields.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
COMPOSITES SCIENCE AND TECHNOLOGY
·
2023
·
IF 9.1
Lei Feng,Peng Wei,Siyuan Ding,Qiang Song,Jiaxu Zhang,Chenhuan Wang,Liyuan Guo,Dongfang Xu,Haojie Song
Thermally insulating aramid nanofiber (ANF) aerogels enable a wide range of applications but are limited by their low mechanical elasticity. Efficient design of aerogels’ components and microstructures is crucial yet remains highly challenging for effectively improving the flexibility of ANF aerogels. Here, for the first time, we report the incorporation of boron nitride nanoribbons (BNNRs) into ANF aerogel to form a multilayer BNNR/ANF hybrid aerogel, which is prepared by suspension mixing of BNNRs and ANFs followed by a vacuum-assisted and directional solidification process . Flexible BNNRs with a high aspect ratio are uniformly embedded in the ANF networks, giving the ANF aerogel an extremely high mechanical deformability (up to 60 % compressive strain), capable of retaining its elasticity even after 100 compression cycles or in liquid N 2 (−196 °C). Moreover, the introduction of BNNRs does not reduce the thermal insulation capacity of ANF aerogels, while significantly improving their thermal stability and fire resistance. These excellent multifunctionality benefits from the synergistic effect of organic–inorganic components and the multilayer structure of aerogel. This work paves the avenue for developing next-generation elastic and thermal insulating materials with great potential for widespread applications.
研究领域:
材料科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Advanced Science
·
2023
·Vol. 10
·期 35
·2304147
·
IF 15.1
Yi Hou,Guangda Zhu,Samantha O. Catt,Yuhan Yin,Jian Xu,Eva Blasco,Ning Zhao
Most plastics originate from limited petroleum reserves and cannot be effectively recycled at the end of their life cycle, making them a significant threat to the environment and human health. Closed-loop chemical recycling, by depolymerizing plastics into monomers that can be repolymerized, offers a promising solution for recycling otherwise wasted plastics. However, most current chemically recyclable polymers may only be prepared at the gram scale, and their depolymerization typically requires harsh conditions and high energy consumption. Herein, it reports less petroleum-dependent closed-loop recyclable silica-based nanocomposites that can be prepared on a large scale and have a fully reversible polymerization/depolymerization capability at room temperature, based on catalysis of free aminopropyl groups with the assistance of diethylamine or ethylenediamine. The nanocomposites show glass-like hardness yet plastic-like light weight and toughness, exhibiting the highest specific mechanical strength superior even to common materials such as poly(methyl methacrylate), glass, and ZrO 2 ceramic, as well as demonstrating multifunctionality such as anti-fouling, low thermal conductivity, and flame retardancy. Meanwhile, these nanocomposites can be easily processed by various plastic-like scalable manufacturing methods, such as compression molding and 3D printing. These nanocomposites are expected to provide an alternative to petroleum-based plastics and contribute to a closed-loop materials economy.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FARADAY DISCUSSIONS
·
2024
·Vol. 252
·52-68
·
IF 3.3
Fengjie Jiang,Zihan Wang,Zhiqi Cong
Cytochrome P450 monooxygenases (P450s) are well recognized as versatile bio-oxidation catalysts. However, the catalytic functions of P450s are highly dependent on NAD(P)H and redox partner proteins. Our group has recently reported the use of a dual-functional small molecule (DFSM) for generating peroxygenase activity of P450BM3, a long-chain fatty acid hydroxylase from Bacillus megaterium. The DFSM-facilitated P450BM3 peroxygenase system exhibited excellent peroxygenation activity and regio-/enantioselectivity for various organic substrates, such as styrenes, thioanisole, small alkanes, and alkylbenzenes. Very recently, we demonstrated that the DFSM-facilitated P450BM3 peroxygenase could be switched to a peroxidase by engineering the redox-sensitive tyrosine residues in P450BM3. Given the great potential of P450 peroxidase for C–H oxyfunctionalization, we herein report scrutiny of the effect of mutating redox-sensitive residues on peroxidase activity by deeply screening all redox-sensitive residues of P450BM3, namely methionines, tryptophans, cysteines, and phenylalanines. As a result, six beneficial mutations at positions M212, F81, M112, F173, M177, and F77 were screened out from 78 constructed mutants, and significantly enhanced the peroxidase activity of P450BM3 in the presence of Im-C6-Phe, a typical DFSM molecule. Further combination of the beneficial mutations resulted in a more than 100-fold improvement in peroxidase activity compared with that of the combined parent enzyme and DFSM, comparable to or better than most natural peroxidases. In addition, mutations of redox-sensitive residues even dramatically increased, by more than 300-fold, the peroxidase activity of the starting F87A enzyme in the absence of the DFSM, despite the far lower apparent catalytic turnover number compared with the DFSM–P450 system. This study provides new insights and a potential strategy for regulating the catalytic promiscuity of P450 enzymes for multiple functional oxidations.
研究领域:
生物化学
·
酶工程
·
合成生物学
✓ 已验证
DOI
高影响因子
Nano-Micro Letters
·
2025
·
IF 36.3
Ruiqi Xu,Hongzhi Cui,Na Wei,Yang Yu,Lin Dai,Xiaohua Chen
Solar-driven interfacial evaporation is one of the most attractive approaches to addressing the global freshwater shortage. However, achieving an integrated high evaporation rate, salt harvesting, and multifunctionality in evaporator is still a crucial challenge. Here, a novel composite membrane with biomimetic micro-nanostructured superhydrophobic surface is designed via ultrafast laser etching technology. Attractively, the double‐transition‐metal (V 1/2 Mo 1/2 ) 2 CT x MXene nanomaterials as a photothermal layer, exhibiting the enhanced photothermal conversion performance due to elevated joint densities of states, which enables high populations of photoexcited carrier relaxation and heat release, provides a new insight into the photothermal conversion mechanism for multiple principal element MXene. Hence, the (V 1/2 Mo 1/2 ) 2 CT x MXene-200 composite membrane can achieve a high evaporation rate of 2.23 kg m −2 h −1 under one sun, owing to the enhanced “light trap” effect, photothermal conversion, and high-throughput water transfer. Synergetically, the membrane can induce the directed precipitation of salt at the membrane edge, thus enabling salt harvesting for recycling and zero-emission of brine water. Moreover, the composite membrane is endowed with excellent multifunctionality of anti‐/de‐icing, anti-fouling, and antibacterial, overcoming the disadvantage that versatility is difficult to be compatible. Therefore, the evaporator and the promising strategy hold great potential for the practical application of solar evaporation.
研究领域:
材料科学
·
能源工程
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Catalysts
·
2023
·Vol. 13
·期 12
·1493
·
IF 3.9
Feiyang Wen,Yuelin Xu,Fengxi Li,Jinglin Ma,Zhi Wang,Hong Zhang,Lei Wang
Disulfides, as fundamental scaffolds, are widely present in peptides, natural products, and pharmaceutical molecules. However, traditional synthesis of disulfides often involves the utilization of toxic reagents or environmentally unfriendly reaction conditions. In this work, a green and efficient method was developed for synthesizing pyrrole disulfides using β-ketothioamides and ethyl cyanoacetate as substrates, with lipase serving as a catalyst. Under the optimal conditions (β-Ketothioamides (1 mmol), ethyl cyanoacetate (1 mmol), PPL (200 U), and EtOH (5 mL)), lipase leads to the formation of pyrrole disulfides in yields of up to 88% at 40 °C. The related mechanism is also speculated in this paper. This approach not only presents a new application of lipase in enzyme catalytic promiscuity, but also offers a significant advancement in the synthetic pathway for pyrrole disulfides and aligns with the current mainstream research direction of green chemistry, contributing to the further development of environmentally friendly biocatalytic processes.Keywords:lipase;catalytic promiscuity;pyrrole disulfide;β-ketothioamides;cyanoacetate
研究领域:
生物化学
·
绿色化学
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Xueyu Li,Jing Wang,Yankun Lin,Yaqi Cheng,Wenjiao Han,Guoliang Yuan,Hongbing Jia
Hydrogel-based wearable sensors have raised great interest due to their potential application in human-machine interfaces and healthcare monitoring. However, there are still challenges in designing hydrogel-based sensors with high mechanical strength , biocompatibility, and multifunctionality. Herein, we designed sensors based on ionic conductive hydrogels composed of poly (acrylamide-co-acrylic acid) (PMAA), poly (vinyl alcohol) (PVA), and ferric chloride (FeCl 3 ) by simple two-steps methods of copolymerization and freezing/thawing. FeCl 3 was used as a cross-linking agent to coordinate with PMAA chains to construct the first network. After being subjected to the freezing/thawing treatment, PVA crystalline domains were formed to serve as knots of the second network. PVA/PMAA/Fe 3+ hydrogels exhibited excellent mechanical properties (maximum tensile strength of 905 kPa, elongation at break of 816%) due to the double physically cross-linked network. Meanwhile, Fe 3+ ions also contributed to the enhancement of the conductivity and sensitivity of hydrogels. Poly (acrylamide-acrylic acid) imparted hydrogels with multifunctional sensing properties. It could accurately and stably detect human body movement, physiology (temperature, sweat), pH change, and touch recognition with excellent biocompatibility. Therefore, this work provides a new route to design ionic conductive hydrogels with high-strength, biocompatibility, and the ability to respond to multiple stimuli, hopefully expanding their applications in flexible sensor devices.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Limeng Song,Bingbing Fan,Yongqiang Chen,Hailong Wang,Hongxia Li,Rui Zhang
Multifunctional high-level performance electromagnetic wave (EMW) absorbing materials is receiving increasing attention with the rapid development of modern information technology. However, current EMW absorbing materials usually have single function and poor thermal and chemical stability, which seriously hinders the practical application of these materials. Herein, to broaden the application fields of the EMW absorption materials, a multifunctional SiC nanofiber aerogel (SiC NFA) was prepared by using chemical vapor deposition (CVD) technology in this work. The as-synthesized SiC NFA exhibits a quite low density (∼9 mg cm −3 ), excellent mechanical performance, high fatigue-resistant, satisfactory refractory property, high temperature thermal stability and good thermal insulation performance. Moreover, the oil-modified SiC NFA has a dramatic hydrophobicity , resulting in a good self-cleaning performance. This SiC NFA also achieves a superior EMW-absorbing property with a minimum refection loss (RL min ) value of −39.37 dB at 7.04 GHz when its thickness is 1.9 mm. These inspiring findings lay a foundation for the subsequent development of multifunctional EMW absorbents.
研究领域:
材料科学
·
电磁学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）