FOOD CHEMISTRY
·
2024
·
IF 8.5
Chuang Yang,Yufei Zhang,Yuanzhi Xu,Yibin Zhou,Shiyi Li,Mingming Zheng
An applicable and highly efficient methodology for the preparation of medium- and long-chain triglycerides (MLCTs) via the enzymatic transesterification of coconut oil with long-chain fatty acid triglycerides, named camellia oil, olive oil, linseed oil, algal oil, and rapeseed oil, respectively, has been proposed. The novel system achieved equilibrium in 5 min, and the MLCT yield ranged from 78.7 to 83.8 %. This is the fastest record reported to date. The catalytic efficiency of the novel biocatalyst, CSL@HMS-C 8 , was 140 g/g•h, 1.43 times higher compared to the control (free lipase), and it retained 62.5 % of its relative activity after 15 cycles. A UPLC-MS provided an accurate structural analysis of the MLCTs, and molecular docking analysis was performed to understand the binding interactions between the protein and molecules. The method of preparing MLCT enriched with functional fatty acids in this paper is efficient, broadly applicable, economical, and promising for industrial applications.
研究领域:
生物化学
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食品科学
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工业生物技术
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产品关联
DOI
PubMed
高影响因子
Cell Reports
·
2024
·
IF 7.5
Lihong Sheng,Jianpeng Gao,Qingyuan Wei,Ye Gong,Zhi-Xiang Xu
Lipid droplets (LDs) are dynamic organelles essential for lipid storage and organismal survival. Studies have highlighted the importance of glial function in brain LD formation during aging; however, the genes and mechanisms involved remain elusive. Here, we found that Ugt35b , a member of the uridine diphosphate (UDP)-glycosyltransferases that catalyze the transfer of glycosyl groups to acceptors, is highly expressed in glia and crucial for Drosophila lifespan. By integrating multiomics data, we demonstrated that glial Ugt35b plays key roles in regulating glycerolipid and glycerophospholipid metabolism in the brain. Notably, we found that Ugt35b and Lsd-2 are co-expressed in glia and confirmed their protein interaction in vivo . Knockdown of Ugt35b significantly reduced LD formation by downregulating Lsd-2 expression, while overexpression of Lsd-2 partially rescued the shortened lifespan in glial Ugt35b RNAi flies. Our findings reveal the crucial role of glial Ugt35b in regulating LD formation to maintain brain lipid homeostasis and support Drosophila lifespan.
研究领域:
神经科学
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衰老研究
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分子生物学
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遗传学
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产品关联
DOI
PubMed
高影响因子
Catalysis Science & Technology
·
2025
·
IF 4.2
Dajian Li,Alfin Kurniawan,Tania Roy,Jin Wang,Cheng lan Liu,Ze Zhen Wang,Rong Zhen Mu,Chun Hui Zhou
The efficient production of allyl alcohol from glycerol is of great importance due to its significance as a valuable intermediate in chemical industries. While catalytic conversion of glycerol to allyl alcohol by solid acid catalysts, carbon deposition (coking) is prone to occur on the catalyst surface, leading to slow down the conversion process and fast deactivation of the catalyst. In this study, we obtained an efficient catalyst for the preparation of allyl alcohol from gas-phase glycerol by controlling the pore structure and surface acidity of the catalyst. The characterization results showed that hydrochloric acid and citric acid removed the silicon and aluminium elements from montmorillonite, and the acidity, pore volume, and surface area ratio of Na-MMT (SBET=34.5 m2 g-1, VT=0.19 cm3 g-1) of the porous montmorillonite(HA1MMT) catalyst were all improved (SBET=97.9 m2 g-1, VT=0.28 cm3 g-1); After adding MoOx and VOx, the selectivity of Mo/V-HA1MMT catalyst for allyl alcohol was improved. The XPS characterization results indicate that the synergistic effect of Mo and V can promote the transfer of electrons during the reaction process of glycerol conversion. Within 480 minutes of catalyzing glycerol dehydration reaction, Mo0.6V0.4(5)-HA1MMT was almost deactivated (Conv.= 19.5%, Sel.allyl alcohol=31.2%) due to carbon deposition. When the catalyst was doped with calcium and magnesium components, a new active phase CaMo4 was discovered on the catalyst, and the acidity of Ca0.5Mg0.5-Cat. (Cat. is Mo0.6V0.4(5)-HA1MMT) decreased to 214.0 μmol g-1. The coking resistance performance of Ca0.5Mg0.5-Cat. was improved, and after 660 minutes of reaction, the catalyst was deactivated (Conv.= 32.1%, Sel.allyl alcohol=30.1%) due to carbon deposition. During the 3rd catalyst regeneration test, Ca0.5Mg0.5-Cat. still maintained high activity (Conv.= 63.3%, Sel.allyl alcohol=35.2%, Sel.acrolein=31.2%). The results of this study indicate that suitable pore structure and acidity are crucial for designing a catalyst with coking resistance properties.
研究领域:
化学工程
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催化科学
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产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2017
·Vol. 134
·期 20
·
IF 1.86
Bo Shi,Liang Liang,Hui Yang,Liming Zhang,Fuan He
Spirulina–poly(vinyl alcohol) (PVA)–glycerol (SPG) films with improved mechanical performance, especially tensile strength (TS) and the elongation at break (EAB), are fabricated by a casting method. The integrity, color, solubility, microstructure, thermal properties, tensile strength, and compatibility of the SPG films are assessed. SPG films became smooth, homogeneous, and flexible after plasticizing with glycerol. The presence of PVA and hydrogen bonding of PVA with glycerol and spirulina protein improves the water resistance of SPG films by decreasing water absorption of spirulina protein and decreasing water diffusion through the films. The amount of carbonaceous residues decreases from 31% to 14% because of the co-pyrolysis of spirulina, PVA, and glycerol. TS increases from 2.5 to 26 Mpa and modulus from 53 to 610 Mpa with increasing PVA content. Glycerol enhances film flexibility and EAB up to 50%. Spirulina can be composited with hydrophilic polymers to fabricate compatible, processable and thermally recyclable films with desirable mechanical performance. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 44842.
研究领域:
材料科学
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生物工程
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
·
2023
·
IF 5.2
Wenjie Sun,Tong Xiao,Qingyi Liu,Jiateng Zhao,Changhui Liu
Glycerol is a bio-based low-cost chemical, which has been widely studied in the field of heat conduction because of its wide working temperature range and superior thermopysical. However, high viscosity of glycerol is a prominent problem that limit the application of glycerol. In this work, low viscosity and high thermal conductivity of glycerol nanofluids are prepared under the dual role of nanoparticles, in which nanoparticles work as the nanoadditives enable an enhancement of thermal conductivity and specific heat capacity of nanofluids and the catalyst make a decline of viscosity of nanofluids. The thermal and viscosity properties of the nanofluid were investigated, and the addition of 15% acetylacetone and 2% TiO 2 increased the thermal conductivity of the nanofluid to 0.3194 W/m·K, which was 8.12% higher than that of the glycerol. Meanwhile, the viscosity was reduced to 357.4 mPa (30 °C) with 15% acetylacetone and 0.5% TiO 2 nanoparticles, which was 47% lower than that of glycerol at the same temperature. Additionally, results of fourier transform infrared spectrometer and proton nuclear magnetic resonance demonstrate that acetal reaction plays an important role in reducing the viscosity of nanofluids, meanwhile, the tests of X-ray diffraction show that nanoparticles can be utilized circularly.
研究领域:
材料科学
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热管理工程
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化学工程
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产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Yangqin Liu,Lei Chen,Lin Liu,Pengfei Shi,Junhui Sun,Yang Wang,Linmao Qian
Reducing wear and even achieving superlubrication in industrial applications using simple yet effective methodologies has been a longstanding research objective. In this study, we propose a convenient approach by employing a combination of carboxylated graphene (Gr-COOH) coating with glycerol as lubricants. Compared to the non-lubricated state, this strategy enabled the achievement of superlubrication with an exceptionally low friction coefficient of 0.002, while simultaneously reducing wear volume of substrate by 4 orders of magnitude, and the wear of the counterpart balls are nearly zero. The transfer of Gr-COOH to the ball surface led to the formation of a low shear resistance interface with the Gr-COOH present on the substrate. Nanoscopic experiments with atomic force microscopy revealed that the substrate surface lubricated by this method exhibited more hydrophilic properties. The formation of a featured hydrophilic interface enables the persistence of glycerol molecules in the contact region for an extended duration, thereby facilitating continuous elastohydrodynamic lubrication. This proposed lubrication methodology holds broad utilization potential as a wear-reduction strategy across various industrial fields.
研究领域:
材料科学
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摩擦学
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产品关联
DOI
高影响因子
ChemCatChem
·
2022
·Vol. 14
·期 10
·e202200011
·
IF 5.497
Dan Yang,Xuan Liu,Fei Song,Yihu Dai,Xiaoyue Wan,Chunmei Zhou,Yanhui Yang
Graphical Boosted : Pt/MnO 2 /CNT catalysts were utilized to chemoselective oxidation of glycerol, in which MnO 2 not only boosted the catalytic activity but also accelerated the activation of the formyl C−H bond in GLYAD to form GLYA. The metal oxide promoters remarkably enhance the catalytic activity of supported Pt catalysts in the glycerol oxidation toward glyceric acid, whereas the primary factor that metal oxide promotes the reaction, as well as the kinetics relevant step remain indistinct. Herein, manganese dioxide (MnO 2 ) is chosen as a model to uncover the role of promoter in the glycerol oxidation over Pt-based catalyst in alkali-free solution. The results prove that the superior catalytic performance is mainly attributed to the increased synergistic interaction between Pt particles and the metal oxides to boost the activation of oxygen (not glycerol), while the increased dispersion shows slight effect. Furthermore, the detailed kinetic studies reveal that MnO 2 is prone to accelerate the awkward step of glyceraldehyde to glyceric acid, and the lattice oxygen of MnO 2 also involves in this particular step.
研究领域:
催化
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化学工程
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材料科学
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物理化学
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产品关联
DOI
高影响因子
Biotechnology for Biofuels
·
2020
·Vol. 13
·期 1
·1-14
·
IF 4.815
Wang Xiang,Liu Si-Fen,Li Ruo-Yu,Yang Wei-Dong,Liu Jie-Sheng,Lin Carol Sze Ki,Balamurugan Srinivasan,Li Hong-Ye
Background Despite the great potential of marine diatoms in biofuel sector, commercially viable biofuel production from native diatom strain is impractical. Targeted engineering of TAG pathway represents a promising approach; however, recruitment of potential candidate has been regarded as critical. Here, we identified a glycerol-3-phosphate acyltransferase 2 (GPAT2) isoform and overexpressed in Phaeodactylum tricornutum.Results GPAT2 overexpression did not impair growth and photosynthesis. GPAT2 overexpression reduced carbohydrates and protein content, however, lipid content were significantly increased. Specifically, TAG content was notably increased by 2.9-fold than phospho- and glyco-lipids. GPAT2 overexpression elicited the push-and-pull strategy by increasing the abundance of substrates for the subsequent metabolic enzymes, thereby increased the expression of LPAAT and DGAT. Besides, GPAT2-mediated lipid overproduction coordinated the expression of NADPH biosynthetic genes. GPAT2 altered the fatty acid profile in TAGs with C16:0 as the predominant fatty acid moieties. We further investigated the impact of GPAT2 on conferring abiotic stress, which exhibited enhanced tolerance to hyposaline (70%) and chilling (10 ºC) conditions via altered fatty acid saturation level.Conclusion sCollectively, our results exemplified the critical role of GPAT2 in hyperaccumulating TAGs with altered fatty acid profile, which in turn uphold resistance to abiotic stress conditions.
研究领域:
海洋生物学
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合成生物学
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代谢工程
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DOI
PubMed
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 86
·54823-54828
·
IF 3.108
Junrong Li,Liangjing Fang,William R. Tait,Luyi Sun,Lihong Zhao,Liying Qian
Conductive composite hydrogels based on sodium carboxymethyl cellulose (CMC) and polyaniline (PAn) were prepared via the semi-interpenetrating polymer network (semi-IPN) method, using glycerol diglycidyl ether (GDE) as the crosslinking agent. The structures of the resulting composite hydrogels were characterized by 13C-NMR, FT-IR, and SEM. The composite hydrogels with various concentrations of CMC presented a similar swelling kinetic behaviour and a relatively high swelling ratio. With increasing CMC concentration, both the compressive fracture stress and modulus of the composite hydrogels improved gradually. Though the modulus of the composite hydrogels increased with more GDE added, the compressive fracture stress decreased when the crosslinking density was too high. The electrical conductivity of the composite hydrogels increased first and then decreased slightly with increasing dosages of CMC and GDE. Doping with aromatic sulfonate is a good approach to improve the conductivity of the composite hydrogels and the conductivity reached 6.31 × 10−3 S cm−1 after doping with sodium benzene sulfonate (BSNa).
研究领域:
材料科学
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化学工程
✓ 已验证
产品关联
DOI
高影响因子
Catalysts
·
2019
·Vol. 10
·期 1
·43
·
IF 3.444
Xincheng Wang,Fenghe Zhao,Long Huang
Temperature programmed surface reaction (TPSR) was developed as a method for rapid screening of catalysts. In this study, a series of acid catalysts was screened for the low-temperature dehydration of glycerol to acrolein via TPSR. Results suggested that most catalysts show activity of glycerol conversion to acrolein at a greatly different temperature range. HY, SiO2supported H4SiW12O40(STA/SiO2), SO42−/ZrO2, and SO42−/TiO2were observed to be efficient for the conversion of glycerol into acrolein at 210 °C, which was significantly lower than that generally reported (250–340 °C). Moreover, high selectivity of acrolein was gained at 85% and 86% over SiW/SiO2and SO42−/TiO2, respectively. A new style catalyst, ZnCl2/SiO2, was also found to be highly selective to acrolein and evaluated in a conventional fixed-bed reactor. Especially, stability tests showed that the catalyst life was up to 300 h with no clear deactivation on ZnCl2/SiO2with hydrogen as dilution.Keywords:glycerol;low temperature dehydration;acrolein;TPSR
研究领域:
化学工程
·
催化科学
✓ 已验证
产品关联
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2025
·
IF 3.9
Bowen Tan,Danru Xu,Mengmeng Jin,Bolun Yang,Zhun Hu,Jingjun Liu
Cerium dioxide (CeO2) with different morphologies was synthesized via a hydrothermal method and applied to the carbonylation of glycerol with CO2. Subsequent characterization through H2-TPR and catalytic activity tests demonstrated that CeO2 nanorods exhibited the highest oxygen storage/release capacity as well as enhanced catalytic performance compared to other morphologies. CeO2 nanorods were thus further modified through hydrogen reduction at varying temperatures, aiming to tune the density of the oxygen vacancies. Characterization via BET, NH3-TPD, CO2-TPD, XPS, and ESR indicated that variations in morphology and reduction temperature influenced the microstructural characteristics and the strength of the acid–base sites of the catalysts. Notably, hydrogen reduction created more oxygen vacancies in the CeO2 nanorods, with the concentration of these vacancies increasing with higher reduction temperatures. Furthermore, the catalytic activity of CeO2 in glycerol carbonylation with CO2 showed a positive correlation with the concentration of oxygen vacancies. Optimizing CeO2 catalysts can enhance its performance in activating CO2, providing new ideas for industrial CO2 resource utilization and carbon capture technology development.
研究领域:
催化化学
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材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2024
·
IF 11.2
Deshuai Kong,Biao Yang,Hua Yuan,Cong Du,Yeqiang Tan
As a biomass material with biodegradability and biocompatibility, sodium alginate (SA) is a good candidate for constructing hydrogels for tissue-mimicking and biomedical scaffold fabricating through extrusion-based 3D printing technology. However, the mechanical strength and stiffness of alginate hydrogels are still not comparable with biological tissues such as tendons and the printability of SA solutions is often poor. Here, a novel strategy for 3D printing of alginate hydrogels with high mechanical performance is developed by using glycerol as a co-solvent for SA solutions. The addition of glycerol (GL) enables the formation of a homogenous SA/GL solution with a high solid content of 12–20 wt.% and endows crosslinked SA hydrogels with high stretchability. By applying uniaxial stretches, hydrogel filaments prepared with concentrated SA/GL solutions reveal a high tensile strength of 36.6–161.3 MPa, Young's modulus of 59.2–1964.2 MPa, and elongation at break of 8.5 %–106.2 % due to the high orientated and closely packed SA chains. SA/GL solutions become more solid-like with increasing SA concentration, and the solution with a solid content of 16 wt.% exhibits optimal 3D printability because of the appropriate rheological properties and thixotropic behavior. By designing the deforming-and-fixing process, 3D printed high-strength alginate hydrogels with complex structures are prepared, broadening the application of alginate hydrogels in load-bearing and biomedical fields.
研究领域:
生物材料学
·
组织工程学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）