JOURNAL OF MEMBRANE SCIENCE
·
2019
·
IF 7.015
Jian Zhou,Dan Sun,Lei Wang,Leiming Guo,Wei Chen,Fengjiao Yu,Yong Wang,Yang Yang
Mixed-matrix membranes blended with nanosized inorganic fillers have been widely used in ultrafiltration (UF) for large molecule separation. In this work, we provide a feasible route to construct mixed-matrix polysulfone (PSf) UF membranes via the nonsolvent-induced phase inversion process, utilizing sheet-like copper iodide superstructures (s-CuI) as fillers. The size of s-CuI in lateral dimension reaches micrometer scale, but the nanosheets can be well embedded in the polymer matrix with their 2D basal planes parallel to the membrane surface . On account of the stacking straight-through channel structure of s-CuI and its large dimension spanning across multiple membrane pores within the layer, the PSf membrane blended with 0.8 wt% content of s-CuI displays optimal UF performance with a pure water permeation (PWP) of 1473 L/(m 2 h bar) and a bovine serum albumin (BSA) rejection of 92%. In contrast, the pure PSf membrane only presents a PWP of 556 L/(m 2 h bar) and a BSA rejection of 58.2%. Besides, the enhancement of mechanical stability for the PSf/s-CuI 0.8% membrane is significant and the leakage of the s-CuI filler is negligible. Though the antifouling performance of the PSf/s-CuI 0.8% membrane against the protein BSA is limited, its flux is always 2–3 times higher than that of the pure PSf membrane in each step during a sequential test of fouling behavior . This study indicates that it is highly promising to employ designable superstructures as functional fillers to construct novel mixed-matrix membranes with good interfacial compatibility and superior performance.
研究领域:
材料科学
·
膜分离技术
·
高分子化学
·
纳米复合材料
·
生物分离工程
✓ 已验证
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2017
·
IF 6.035
Huiqing Wu,Yuejun Liu,Long Mao,Chunhai Jiang,Jiaming Ang,Xuehong Lu
To prepare an ultrafiltration membrane with simultaneous self-cleaning and self-protection abilities, TiO 2 -polydopamine (PDA) nanohybrid are facilely prepared and used to functionalize polysulfone (PSf) membrane matrix. In the TiO 2 -PDA nanohybrid , PDA spheres acts as an adhesive substrate to hold densely covered photocatalytic TiO 2 nanoparticles , and also serves as a free-radical scavenger to protect PSf membrane against the damage by free radicals produced by TiO 2 during UV exposure treatment. The spherical-shaped TiO 2 -PDA can be easily doped into PSf membrane via phase inversion method, which allows the hydrophilic TiO 2 -PDA spheres migrating to the hydrophobic PSf surface and benefiting the antifouling ability. As a result, the TiO 2 -PDA/PSf hybrid membrane exhibits excellent overall performances in separation efficiency, remarkable self-cleaning property and performance stability under UV irradiation, in comparison with PSf and TiO 2 /PSf membrane. The influence of TiO 2 -PDA content on the membrane properties is also investigated, and it is found the hybrid membrane with 0.8 wt% TiO 2 -PDA possesses the optimal performance.
研究领域:
材料科学
·
环境工程
·
膜技术
✓ 已验证
DOI
高影响因子
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
·
2016
·Vol. 105
·期 7
·1737-1746
·
IF 2.881
Weiping Wang,Zhi Zheng,Xin Huang,Wenling Fan,Wenkui Yu,Zhibing Zhang,Lei Li,Chun Mao
Polyethylene glycol (PEG) and heparin (Hep) were grafted onto polysulfone (PSF) membrane by plasma-induced surface modification to prepare PSF–PEG–Hep membranes used for artificial lung. The effects of plasma treatment parameters, including power, gas type, gas flow rate, and treatment time, were investigated, and different PEG chains were bonded covalently onto the surface in the postplasma grafting process. Membrane surfaces were characterized by water contact angle, PEG grafting degree, attenuated total reflectance-Fourier transform infrared spectroscopy, ultraviolet–visible spectrophotometry, X-ray photoelectron spectroscopy, critical water permeability pressure, and scanning electron microscopy. Protein adsorption, platelet adhesion, and coagulation tests showed significant improvement in the hemocompatibility of PSF–PEG–Hep membranes compared to pristine PSF membrane. Gas exchange tests through PSF–PEG6000–Hep membrane showed that when the flow rate of porcine blood reached 5.0 L/min, the permeation fluxes of O 2 and CO 2 reached 192.6 and 166.9 mL/min, respectively, which were close to the gas exchange capacity of a commercial membrane oxygenator. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1737–1746, 2017.
研究领域:
生物材料
·
生物医学工程
·
表面化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2025
·
IF 3.9
Xiuhua Sun,Xinyao Wang,Fuyu Sun,Changlu Gao
A novel chloromethylation (CM) approach was developed to graft the macroinitiator −CH2Cl onto aromatic backbone-bearing polymer materials such as polysulfone (PSf) in the aqueous phase, followed by atomic transfer radical polymerization (ATRP) of zwitterionic polysulfobetaine methacrylate (PSBMA) for antifouling modification. This CM reaction was completed in one step using a mixture of paraformaldehyde, hydrochloric acid, and a phase transfer catalyst (PTC), i.e., 3-(pyridinium-1-yl) propane-1-sulfonate inner salt. Advantages of the described method include: (1) No environmentally hazardous catalysts, such as SnCl4 and ZnCl2, were used. (2) The PTC was chemically stable and recyclable, which was superior to the water-sensitive, almost nonrecyclable Lewis acid. (3) The CM reaction occurred in the presence of hydrochloric acid rather than water-sensitive solvents (e.g., chloroform, sulfuric acid) used in the bulk modification method. Membranes were characterized by X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FTIR) to verify the presence of −CH2Cl and PSBMA on the surfaces. Under the optimized CM and ATRP conditions, the obtained polysulfone membranes showed a water contact angle (WCA) as low as 25°, their pure water flux (PWF) and protein rejection were simultaneously enhanced, and the flux recovery ratio improved from 72.6% to 92.6%.
研究领域:
高分子科学
·
膜科学与技术
·
生物材料
·
表面功能化
·
抗污染材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FIBERS AND POLYMERS
·
2016
·Vol. 17
·期 11
·1820-1828
·
IF 1.022
Yang Xue,Liu Hui,Zhao Yanjiao,Liu Lifang
Cellulose nanocrystals (CNCs) extracted from corn husks were used as additive to modify the hydrophilicity and anti-fouling properties of polysulfone (PSf) membrane. The PSf/CNCs blend membranes were prepared via an immersion phase inversion method. The influence of CNCs content on the morphology, structure, and performances of PSf membrane were carefully investigated by SEM, TG, DTG, DSC, break strength, elongation-at-break, Young modulus, contact angle and filtration experiment. The results showed that the isolated CNCs from corn husks were a promising additive for modifying the properties of PSf membrane. CNCs can improve mechanical property, thermal stability, hydrophilicity and anti-fouling performance of the pure PSf membrane. The PSf/CNCs blend membrane reached optimal properties at 2 wt% CNCs content, which was 2.76 and 1.57 times in pure water flux and FRR values respectively as compared to pure PSf membrane. Meanwhile, PSf-2 also can maintain a relatively high BSA rejection.
研究领域:
材料科学
·
纳米技术
·
膜技术
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2018
·
IF 3.997
Mingbo Ji,Xiangrong Chen,Jianquan Luo,Yinhua Wan
Two anticoagulant proteins, nattokinase and lumbrokinase, were successfully immobilized onto the dopamine-coated polysulfone (PSf) membrane surface by covalent bonding. X-ray photoelectron spectroscopy (XPS) and Zeta potential measurement confirmed the immobilization of these anticoagulant proteins. The immobilization yield of nattokinase and lumbrokinase reached to 35.2 and 33.4 μg/cm 2 , respectively. The water contact angle measurement revealed that the membrane surface hydrophilicity was improved after immobilizing the anticoagulant proteins. Meanwhile, the immobilized proteins retained their biological activity. Then blood compatible tests demonstrated that the modified membranes had lower static protein adsorption, platelet/erythrocyte adhesion, hemolysis, as well as longer blood clotting time, compared to virgin PSf membrane. In addition, the nattokinase-immobilized membrane showed a higher blood compatibility than BSA and lumbrokinase immobilized memrbanes, due to its’ high bioactivity. Our research demonstrates that the dopamine-assisted immobilization of nattokinase and lumbrokinase can endow the membranes with improved blood compatibility as well as high biological activity, which may be expected to apply to blood-contacting materials.
研究领域:
生物材料
·
生物医学工程
·
血液相容性
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2020
·
IF 7.183
Yang Liu,Guiliang Li,Qiu Han,Haibo Lin,Qiang Li,Jing Hua,Fu Liu
Inhibiting thrombosis in extracorporeal dialyzer is predominantly determined by the compatible interface design. It is challenging to develop anticoagulant dialyzers for clinical heparin free dialysis. Herein, we develop an environmentally friendly approach to construct a hydrogel skin composed of poly (sodium alginate-acrylic acid) P (SA-AA) network on polysulfone (PSf) membranes via pre-seeding initiator into membrane matrix and subsequently crosslinking SA and AA in aqueous solution. Physicochemical properties of modified membranes with different SA/AA ratio were characterized by attenuated total reflectance fourier transform infrared spectra (ATR-FTIR) spectrum, proton nuclear magnetic resonance ( 13 C NMR), scanning electron microscopy (SEM) and atomic force microscope (AFM) and contact angle. Antifouling property was demonstrated by proteins adsorption and E. coli adhesion. Hemocompatibility was comprehensively evaluated by hemolysis ratio, anticoagulation activity (APTT and TT), complement activation, platelets activation and contact activation. Anticoagulant dialyzer was fabricated via skin implantation strategy to implement a chronic renal swine dialysis with heparin free administration. Clotting was significantly inhibited during the whole dialysis session, moreover, the dialyzer showed improved toxins clearance, including urea (~185 mL/min), creatine (~153 mL/min), inorganic phosphorous (~120 mL/min) and β 2 -microglobulin (~110 mL/min). The modified membrane bearing abundant carboxylate groups contributes to excellent hydrophilicity and Ca 2+ chelation capability, which is considered to be the predominant anti-clotting mechanism via both intrinsic and extrinsic cascades. The anticoagulant PSf dialyzer demonstrates promising clinical application for heparin free dialysis.
研究领域:
生物医学工程
·
材料科学
·
血液透析
·
生物材料
✓ 已验证
产品关联
DOI
高影响因子
Biomedical Materials
·
2015
·Vol. 10
·期 6
·065022
·
IF 3.697
Weiping Wang,Xin Huang,Haiyan Yin,Wenling Fan,Tao Zhang,Lei Li,Chun Mao
In this study, polyethylene glycol acrylate (PEGA) was introduced onto the surface of polysulphone (PSF) membrane to prepare PSF–PEGA membranes through low-temperature plasma technology for haemocompatibility improvement of artificial lungs. The effects of plasma power, PEGA solution concentration and dipcoating temperature on surface modification were systematically investigated. Results of Fourier transform infrared spectroscopy, x-ray photoelectron spectroscopy and PEGA grafting degree confirmed that PEGA was successfully grafted onto the PSF membranes. Contact angle values showed that the hydrophilicity of the PSF–PEGA membrane surface increased by 21.5%. The results of the protein adsorption, platelet adhesion and coagulation tests further showed the excellent haemocompatibility of the modified membrane. Gas exchange tests also revealed that at a porcine blood flow rate of 5 l min−1, O2 and CO2 exchange rates through the PSF–PEGA membrane were 198.6 and 170.9 ml min−1, respectively; approximately this is the gas exchange capacity of commercial respiratory assistance devices.
研究领域:
材料科学
·
生物医学工程
·
医疗器械
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2025
·Vol. 48
·期 7
·e70219
·
IF 2.8
Xiao-Bei Huang,Yong-Ming Wei,Lin Yu,Zhen-Liang Xu,Hu Yang
Immobilized metal affinity chromatography is a green method applied to the separation and purification of proteins and biomolecules in downstream processing. With its unique internal pores, the membrane carriers have more active sites than typical magnetic nanoparticles and beads. It also greatly overcomes the mass-transfer resistance brought by traditional column chromatography. In this study, polysulfone was selected as the pristine membrane. Tannic acid and 3-aminopropyltriethoxysilane coatings were employed to construct the secondary reaction platform, which was then covalently coupled with polyethyleneimine and grafted with iminodiacetic acid groups to chelate Cu 2+ . Bovine serum albumin was utilized as the adsorption protein to adjust and optimize the modification parameters. The results demonstrated that the adsorption amount per unit membrane area reached 0.19 mg/cm 2 under the solution condition of pH 8.5. The adsorption thermodynamics followed the Langmuir model, and the corresponding model parameters were obtained.
研究领域:
生物技术
·
生物化学
·
材料科学
·
分析化学
·
分离科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 47
·41323-41330
·
IF 3.289
Qiao-Ling Gao,Fei Fang,Chen Chen,Xue-Yan Zhu,Jing Li,Hong-Ying Tang,Zhong-Biao Zhang,Xiao-Jun Huang
A versatile strategy to fabricate newly-developed silica-modified membranes based on organic/inorganic hybridization for oil/water separation is described in this study. The modified membranes are easily obtained by a simple two-step immersion of polysulfone hollow fiber membranes with radial gradient microstructure (RGM-PSF) into a silicon solution of tetraethyl orthosilicate (TEOS) mixed with 3-glycidyloxypropyltrimethoxysilane (GOPTS) and subsequently into a lactic acid solution. Attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS) and field emission scanning electron microscopy (FE-SEM) were utilized to characterize the surface compositions and microstructures. A micro/nano-scaled SiO2-based coating was generated roughly and continuously on the membrane surfaces, endowing them with superhydrophilicity and underwater superoleophobicity. Results of dead-end filtration experiments demonstrated that the hybridized RGM-PSF membranes could be applied in oil-in-water emulsion separation far more efficiently, with higher water permeate flux, better oil rejection ratio, and higher pressure endurance than those of the common ones. Therefore, this study has provided a facile approach to prepare silica-modified membranes with special wettability, showing prominent application prospects for oily wastewater treatment in practical processes.
研究领域:
材料科学
·
环境工程
·
膜技术
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Zhefu Wu,Qing Su,Jie Yang,Zhimei Wei,Gang Zhang
Particulate matter 2.5 (PM 2.5 ) has become a major threat to human lives. To minimize the adverse effect of high temperature PM 2.5 , the best way is to alert and filter out the PM 2.5 simultaneously. However, it remains a challenge to design filters with combined merits of high-performance, fire-retardancy and thermal response. In this work, we prepare the thermochromic luminous polysulfone membrane with high-temperature PM 2.5 filtration and alarming property. The dual luminous center containing covalent donor–acceptor (DA) structure and metal–ligand interaction are incorporated and electrospun into structure unified nanofibers. And different thermal responsiveness is observed for the dual luminous center. The high PM 2.5 filtration efficiency (99.1%), low pressure drops (98 Pa) and heat-resistant (T g > 236 °C) membrane can be directly applied on an in-situ high-temperature PM 2.5 filtration and monitoring device, with the emission color variable from red to cyan in a wide range. More importantly, PBN composite filters show excellent flame retardancy in comparison with the commercial PE fabrics, and the color indicating property functions well even under fire. Therefore, the PBN composite membrane holds great potential in the fields of high-temperature PM 2.5 filtration and fire alarming.
研究领域:
材料科学
·
环境科学
·
纳米技术
·
消防安全工程
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2019
·Vol. 9
·期 11
·6254-6266
·
IF 3.049
Ming-Ming Tu,Jing-Jie Xu,Yun-Ren Qiu
In this study, acrylic acid (AA) and sulfonated hydroxypropyl chitosan (SHPCS) were covalently grafted on the PSf membrane surface to improve its hemocompatibility. First, the modified AA-PSf membrane was obtained through the Friedel–Craft reaction between acrylic acid and the PSf membrane surface. Then, the modified SHPCS-AA-PSf membrane was prepared by grafting SHPCS onto the AA-PSf membrane surface via the dehydration acylation of the carboxyl group of the AA-PSf membrane with the amino group of SHPCS. ATR-FTIR and XPS measurements confirmed that the –COOH group and SHPCS were successfully grafted onto the surface of the PSf membrane. The modified PSf membranes showed suppressed platelet adhesion and lower protein adsorption (161 μg cm−2) compared with the pristine PSf membrane (341 μg cm−2). Hemocompatibility testing showed that modified membrane materials had a prolonged clotting time, plasma recalcification time (PRT), activated partial thromboplastin time (APTT), thrombin time (TT), and prothrombin time (PT). All of these results indicated that the surface modification of the PSf membrane with acrylic acid and SHPCS had good hemocompatibility and anticoagulant property.
研究领域:
材料科学
·
生物材料
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）