NEW JOURNAL OF CHEMISTRY
·
2017
·Vol. 41
·期 16
·7924-7931
·
IF 3.269
Aiping Gao,Yiran Li,Haiting Lv,Dan Liu,Na Zhao,Qianqian Ding,Xinhua Cao
In this study, a new gelator containing lenalidomide and cholesterol groups was synthesized, which could form stable gels in 1,4-dioxane and mixed solvents of DMF/H2O (v/v, 1/1). The self-assembly process was studied and certified by field emission scanning electron microscopy, UV-vis, IR, XRD, and CA. Based on the results obtained from the abovementioned analyses, the self-assembly structure, aggregation pattern, and surface wettability could be tuned via the addition of melamine due to intermolecular hydrogen bonding between compound 1 and melamine (MA). The irregular lumpy and the closely packed fiber structures could be turned into microbelt and sparse fiber structures after the addition of MA, respectively. Moreover, the hydrophobicity of the xerogel film of 1-MA was obviously increased. The mechanical strength of gel 1-MA was obvisously enhanced due to the addition of MA. The UV-vis, IR, and XRD experiment results showed that the self-assembly process and mode of 1 was changed due to the addition of MA through intermolecular hydrogen bonding between 1 and MA. Therefore, these results provide a method for the regulation of the self-assembly process via intermolecular noncovalent interaction.
研究领域:
化学
·
材料科学
·
生物医学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2024
·
IF 8.1
Xin Sun,Jun Wang,Jing Yu,Yifu Jing,Jingyuan Liu,Manish Singh,Peter D. Lund,Muhammad Imran Asghar
Atomic isolated and dispersed single atom catalyst is ideal for high-performance industrial catalyst. However, the contribution from small amounts of nanoclusters coexisting with single atoms to the catalytic reaction activity is often neglected. In this work, a MXene-supported uniformly dispersed Pt single atoms and nanoclusters (Pt 1 +Pt n /MXene) were obtained by self-assembly through an impregnation method. The catalyst exhibits high electrochemical performance in the hydrogen evolution reaction with an overpotential of only 61.3 mV and a Tafel slope of 32.5 mV dec −1 at a current density of 10 mA cm −2 in an acidic environment. The XAFS analysis and further DFT calculation indicate that the synergistic effect between single atoms and nanoclusters can facilitate adsorption of H* and promote the HER reaction. This work provides an efficient method for integrating multiple active sites in noble metal catalysts.
研究领域:
材料科学
·
催化化学
·
能源科学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry B
·
2025
·
IF 5.7
XIAOXIAO YUAN,Xiaoyi Zhang,YIFAN YANG,YAONAN WANG,SHURUI ZHAO,QIQI FENG,Jianhui Wu,MING ZHAO,Shiqi Peng
Here a novel anti-osteoporosis agent UA-RGDS, namely RGDS (Arg-Gly-Asp-Ser) conjugated UA (ursolic acid), was presented. In ultrapure water UA-RGDS existed as the tetramer. In the serum of OVX mice (ovariectomized mice), and at 10-4 M of concentration the self-assemble led UA-RGDS to the formation of nano-particles of 16 nm-156 nm in height, the size of suitably transporting in the blood circulation. In vivo bio-distribution supported that UA-RGDS only distributed in the femur of OVX mice, while null distribution been found in the blood and the other organs. These observations suggested that UA-RGDS was capable of targeting the femur, thereby blocked bone loss. ELISA experiment explored that as anti-osteoporosis agent UA-RGDS down regulated the expressions of IL-1β in the serum OVX mice. Thus UA-RGDS provided a linker for bone loss and down regulation of the expressions of IL-1β, thereby made serum IL-1β to be a biomarker for menopause women clinically.
研究领域:
药理学
·
分子生物学
·
纳米医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Chong Liu,Zhicheng Wang,Na Zhang,Yue Li,Shulin Li,Xia Xin
The precise synthesis and self-assembly of metal nanoclusters (NCs) featuring customized morphologies and structures, represent a crucial step in the exploration of structure-property relationships and the discovery of new functionalities. This study presents a strategy to induce the self-assembly of copper nanoclusters ( Cu-NCs , Cu 4 I 4 (PPh 3 ) 4 ) into stable and highly fluorescent regular micron level hexagonal plates by nonionic surfactant Tyloxapol and mixed solvent (DMSO/H₂O). The aggregation-induced emission (AIE) behavior markedly enhanced the fluorescence quantum yield and lifetime of Ty-Cu-NCs , from 0.57 % and 68.6 ns to 22.60 % and 2.8 μs, representing a ∼40-fold improvement in both. Kinetic studies of the assembly process have revealed a sequence involving nucleation, aggregation, oriented growth and subsequent size enlargement. When varying the types of surfactants, the formation of Ty-Cu-NCs assembly with different morphologies was observed which indicated the unique role of Tyloxapol in directing the formation of hexagonal plates. It is noteworthy that the Ty-Cu-NCs assembly exhibits high selectivity and sensitivity towards Fe³⁺ ions, with a detection limit of 1.51 μM, which is considerably lower than the maximum permissible concentration of Fe³⁺ in tap water as per health standards. The combination of high fluorescence properties and selective ion detection capabilities renders these Ty-Cu-NCs assembly promising candidates for applications in ion sensing and anti-counterfeiting technologies.
研究领域:
材料科学
·
化学
·
分析化学
✓ 已验证
DOI
高影响因子
CHEMBIOCHEM
·
2015
·Vol. 16
·期 11
·1622-1628
·
IF 3.088
Rongqiang Liao,Shouhui Yi,Manshuo Liu,Wenling Jin,Bo Yang
Graphical Get smart: A smart targeting gene carrier for cancer-specific delivery has been successfully prepared by a “multilayer bricks-and-mortar” strategy. Carriers produced by two different self-assembly schemes were investigated for their ability to compact pDNA into nanoparticles. Cell viability studies show that the most suitable (Method A) material has lower cytotoxicity than 25 kDa bPEI and that transfection efficiency is maintained. A targeting gene carrier for cancer-specific delivery was successfully developed through a “multilayer bricks-mortar” strategy. The gene carrier was composed of adamantane-functionalized folic acid (FA-AD), an adamantane-functionalized poly(ethylene glycol) derivative (PEG-AD), and β-cyclodextrin-grafted low-molecular-weight branched polyethylenimine (PEI-CD). Carriers produced by two different self-assembly schemes, involving either precomplexation of the PEI-CD with the FA-AD and PEG-AD before pDNA condensation (Method A) or pDNA condensation with the PEI-CD prior to addition of the FA-AD and PEG-AD to engage host–guest complexation (Method B) were investigated for their ability to compact pDNA into nanoparticles. Cell viability studies show that the material produced by the Method A assembly scheme has lower cytotoxicity than branched PEI 25 kDa (PEI-25KD) and that the transfection efficiency is maintained. These findings suggest that the gene carrier, based on multivalent host–guest interactions, could be an effective, targeted, and low-toxicity carrier for delivering nucleic acid to target cells.
研究领域:
生物医学工程
·
分子生物学
·
药物递送系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Siyu Wu,Xiaojuan Niu,Jiali Chen,Wangni Meng,Han Tao,Jianli Zhou,Yuangen Wu
Kanamycin (KAN) can generate a serious threat to human health due to its tendency to accumulate in food. Current colorimetric strategy for KAN detection still faces some challenges, and nanozyme-based colorimetry is an ideal alternative approach. Herein, a non‑copper-based multivalent laccase mimic named Mn-Car is first synthesized through a self-assembly of manganese ions and the endogenous biomolecule carnosine, which is further used to develop a novel colorimetric method for ultrasensitive and selective detection of KAN. The laccase-like catalytic center is formed through the multidentate chelation bonds between manganese ions and imidazolium groups of histidine as well as carboxyl groups of β-alanine in carnosine. The multivalent oxidation states of manganese dynamically regulate electron transfer pathways through synergistic coordination. The unique Mn-Car architecture drives the efficient generation of superoxide radicals (O 2 · − ) and semiquinone radicals (SQ· − ). Leveraging the excellent laccase-like activity of Mn-Car , a highly sensitive colorimetric method for KAN detection is developed. Mn-Car forms polydentate chelation with the amino and hydroxyl groups in KAN, which can trigger multi-step cascade oxidation reactions that disrupt the structural core of Mn-Car and lead to reduced colorimetric signals. The colorimetric method achieves a limit of detection (LOD) of 0.102 μM and is successfully applied for on-site detection of KAN in water samples and honey, providing a novel platform for antibiotic residue analysis.
研究领域:
分析化学
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纳米技术
·
生物传感
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2025
·
IF 4.6
Xia Liu,Xinxin Wang,Boya Hu,Yani Pan,Xinyu Feng,Anran Yan,Haowei Guo,Yiliang Wei,Tianyuan Chen,Yiqi Ruan,Yuye Yao,Hesham R. El-Seedi,Wen-Wen Zhou,Ping Chen,Qiang Chu
Focusing on the self-assembly process of black tea infusion nanoparticles helps elucidate the formation mechanism of tea cream. Brewing times ranging from 1 to 10 min were systematically assessed in this study, and the release pattern of the major components of the tea infusion was followed and related to the dynamic changes of the components of the black tea cream. The mean particle size of nanoparticles in the black tea infusion gradually increased with increasing brewing time, reaching a maximum (269.84 ± 11.25 nm) at 300 s. The results showed that soluble sugars were the most abundant substances of the tea cream at 60 s, and the proportion changed very little during the process. Proteins and flavonoids were rapidly incorporated into the tea cream, maintaining a concentration trend in accordance with the tea infusion. The percentages of caffeine, theobromine, gallic acid, and catechins in tea cream showed a sudden decrease at 240 s, followed by a gradual increase. This formation of tea cream is pH-dependent, with aggregation and precipitation at pH 0–7 and increased dissociation at pH 7–11. The findings will facilitate a more profound comprehension of the formation mechanism of black tea cream.
研究领域:
食品科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Ping Ye,Heng Ding,Bo Yang,Weimiao Wang,Xiaodong Li,Zhiqiang Qiao,Rui Li,Guangcheng Yang,Guoqing Lv
The ignition strategy of energetic materials using low-energy near-infrared (NIR) laser has garnered significant attention due to its enhanced safety and reliability. This study explores the use of a relatively photosensitive but mechanical insensitive energetic material, DATNBI, to facilitate the self-assembly of nano-CL-20 crystals into polycrystalline particles though solvothermal induction, yielding a rough structure conducive to NIR laser ignition. The findings demonstrate that by adjusting the content of DATNBI, it is possible to achieve micro-nano controllable spherical CL-20/DATNBI (C/D) particles, with CL-20 as the primary component and DATNBI as the auxiliary component. The incorporation of DATNBI and the rough surface structure enhance the light absorption of C/D particles in the NIR band. Additionally, the unique synergistic effect between CL-20 and DATNBI during thermal decomposition further promotes NIR laser ignition. As expected, the C/D particles achieved self-sustained combustion and exhibited excellent combustion performance under a 1064 nm laser, which is challenging to be achieved with raw CL-20 or raw DATNBI. Furthermore, the relatively insensitive DATNBI and spherical structure reduced the impact sensitivity of the C/D particles. This multifunctional material strategy, integrating energy, safety, environment-friendliness, and laser ignition performance, offers a novel approach for laser ignition of energetic materials.
研究领域:
化学
·
材料科学
·
能源与燃料
✓ 已验证
产品关联
DOI
高影响因子
IEEE Transactions on Components Packaging and Manufacturing Technology
·
2024
·
IF 2.3
Yi Zhong,Zhongliang Liu,Binbin Jiang,Dongxiao Yang,Weidong Zhong,Penghui Wu,Tengteng He
Fine-pitch flip-chip Au bumps play a critical role in interconnecting and packaging advanced optoelectronics, historically known for their good corrosion resistance and high reliability. However, this study reveals the susceptibility of Au bumps to corrosion and cracking during 85°C/85%RH high temperature and humidity (THT) reliability testing. Cracks were observed at the under-bump metallization (UBM) interfaces, originating at the bump undercut and propagating towards the bump center. This leads to a dramatic 26.7% reduction in mechanical shear strength, significantly compromising the reliability. The failure mechanism of Au bump was analyzed through the combination of characterization and simulation, which identifies a stress-induced and halogen-enhanced galvanic cell corrosion at the UBM interfaces as the root cause. Furthermore, a protective surface coating strategy involving self-assembled monolayer notably improves bump corrosion resistance, as demonstrated by the absence of strength degradation and interfacial delamination after 500-hour accelerated THT test. These insights are pivotal for advancing reliable, high-performance optoelectronic packaging.
研究领域:
材料科学
·
电子工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Dongyin Li,Fuchao Yang,Xuan Shi,Guangyi Tian,Changhui Fu,Yifan Liu,Zhiguang Guo
In recent years, oil pollution and industrial organic pollutants discharge has become a major problem affecting the ecological and human living environment, and the removal of oil in oily wastewater is increasingly urgent, especially for emulsion separation. Therefore, it is crucial to develop efficient oil–water separation membranes with low cost, green sustainability, and ease of operation. Herein, an ingenious spraying hybrid coatings containing ZIF-67 (Zeolitic Imidazolate Framework-67) and polypyrrole (PPy) onto stainless steel mesh (SSM) and polyvinylidene fluoride (PVDF) was proposed. Through solidification and cooperative self-assembly to build rough structures, oil–water separation membranes ZIF-67@PPy SSM and ZIF-67@PPy PVDF have been obtained, which are hydrophilic and oleophilic in air and superoleophobic underwater. Depending on the scenario, on-demand separation of light oil/water mixtures and oil-in-water emulsions can be easily realized. The resulting oil–water separation membranes performed well that the separation efficiency of ZIF-67@PPy SSM can exceed 99.3% for all kinds of light oil/water mixtures, with a water flux of up to 66250 L/(m2·h), and maintains a separation efficiency of 98.5% even after 50 cycles. ZIF-67@PPy PVDF has a separation efficiency of more than 99.4% for various oil-in-water emulsions, and sustains outstanding performance despite undergoing 10 cycles. In addition, ZIF-67@PPy SSM and ZIF-67@PPy PVDF are sustainable in harsh environments, with good mechanical durability and some antimicrobial properties. The coatings prepared in this work that can be used for the separation of light oil/water mixtures and oil-in-water emulsions, and the proposed combination of multiple separation strategies are expected to improve the selectivity, improve efficiency, enhance contamination resistance, and increase accessibility of oil–water separation technologies.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2020
·
IF 3.557
Jiale Liu,Ye Tian,Lin Ai,Zhennan Wu,Dong Yao,Yi Liu,Bai Yang,Hao Zhang
Self-assembly is a powerful technology to construct nanomaterials with helical structures. However, using metal nanoclusters (NCs) as the building blocks for the construction of helical architectures is still rarely reported. In this paper, Au NC assembled helical ribbons (Au NCHRs) are successfully constructed by using Au NCs as the building blocks. Effects of heating mode, solvent polarity and ligand length on the self-assembly process of Au NCs are discussed. The results indicate that the lengths of overlapped and nonoverlapped ligands between adjacent Au NCs play the dominated role on adjusting the morphologies of the resulting assemblies. Ligands with appropriate overlap can provide sufficient flexibility for the helical assembly of Au NCs without losing the stability. If the length of the overlapped parts is too long, the assemblies are usually rigid without the helical structure. Instead, the overlength of nonoverlapped ligands will boost the flexibility but damage the structural stability of the assemblies. Since everything in the world is assembled by atoms and molecules, recognizing the self-assembly mechanism of NCs may promote our understanding on the bountiful complexity of life and nature.
研究领域:
材料科学
·
纳米技术
·
化学
✓ 已验证
DOI
高影响因子
Sustainability
·
2022
·Vol. 14
·期 22
·15290
·
IF 3.889
Jiaqi Bu,Lu Yuan,Hongru Jiang,Chongqing Wang
A novel adsorbent (GO-TOA) was prepared by condensation and self-assembly of graphene oxide (GO) and thiourea, and it was characterized systematically. The results revealed that thiourea has anchored on graphene oxide (GO) successfully. The results showed that GO-TOA had a higher adsorption capacity (641.724 mg/g) and adsorption rate (92.32%) than GO (196.8 mg/g and 65.6%), indicating that the introduction of thiourea greatly improved the adsorption capacity of GO. Adsorption kinetics, adsorption thermodynamics isotherm, and adsorption thermodynamics were used to study the adsorption mechanism. The results show that GO-TOA still has an adsorption rate of 90.44% compared with 0 cycles (92.32), indicating that GO-TOA has good activation and regeneration capacity. In addition, ethanol and dilute hydrochloric acid were used for the desorption of MB, and the effect of desorption was found very well. Through reusability experiments, we also found that GO-TOA has excellent application potential. We believe that GO-TOA will be a potential adsorbent for MB.Keywords:adsorbent;methylene blue;thiourea;graphene oxide;self-assembly
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）