DIAMOND AND RELATED MATERIALS
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2022
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IF 3.806
Shurui Xu,Baoqiang Lin,Qihang Huang,Wenting Qiu,Wenqian Yuan,Weirui Xu,Xingfeng Xue,Guoyu Zhong,Wenbo Liao,Wenlong Wang,Xiaobo Fu
Oat-derived N-doped carbon with tunable N content (OA-NCs) were synthesized and applied in alcohol oxidation to selectively produce aldehyde. OA-NCs exhibited unexpectedly high performance in the oxidation of benzyl alcohol, cinnamyl alcohol and furfuryl alcohol. N species were characterized to interpret its promoting effect on their catalytic activity . Oxidation activity of pyridinic N in OA-NCs was sensitive to their structure while reactivity assessment disclosed it was more active to convert alcohols in presence of Fe 3+ , rather than pyrrolic-N or graphite-N. The superoxide radical was evidenced as the most reactive oxygen species in this reaction. The strong metal-support interaction (MSI) between pyridinic N and Fe 3+ , indicated by DFT calculation, was determined to be critical for the high activity of OA-CNs catalysts. The present work provides the insight into the positive effect of N-metal interaction in carbon materials on O 2 activation and explores a green pathway for the selective production of aldehydes.
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JOURNAL OF CONTROLLED RELEASE
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2022
·
IF 11.467
Jianing Zhao,Longbing Ling,Wei Zhu,Tianhao Ying,Tao Yu,Mengmeng Sun,Xuan Zhu,Yuan Du,Leiming Zhang
Atherosclerosis (AS), a leading cause of death worldwide, involves chronic macrophage inflammation from its initiation to the emergence of complications. Targeting plaque inflammation by re-polarizing pro-inflammatory M1 to anti-inflammatory M2 could therefore provide a promising strategy to treat AS, but currently available anti-inflammatory drugs limit clinical outcomes. In this study, we found that kaempferol (KPF) is capable of potential anti-inflammation as a novel drug candidate, which has been scarcely reported. Building upon these findings, we fabricated a macrophage-biomimetic KPF delivery platform, abbreviated as [email protected] to potentiate therapeutic payloads, wherein the designed ROS-responsive Dextran- g -PBMEO NPs with π-π stacking were coated with macrophage membrane (MM) for effective target and accumulation in atherosclerotic lesions. Therapy of [email protected] afforded significant decrease in proliferating macrophage inflammation while went with the reduction of key pro-inflammatory cytokines and re-polarization M1 to M2 phenotype, inducing excellent anti-AS responses in ApoE −/− mice after i.p. delivery. The mechanism of [email protected] was further investigated and found it related to block the ROS/NF-κB signaling pathways. Together with as well demonstrated biosafety profiles, this proof-of-concept opens an instructive door for the study of KPF-mediated nanodrugs in treatment of AS based on biomimetic NPs.
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CHEMOSPHERE
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2022
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IF 8.943
Jie Cheng,Kaidian Zhang,Jiashun Li,Yuyong Hou
Increased hazardous substances application causes more environmental pollution and risks for human health. Microalgae are the important biological groups in marine ecosystem, and considered to be sensitive to environmental pollutants. Therefore, toxicity test on marine microalgae could provide the most efficient method for aquatic toxicity assessment, and could also be used as the early warning signals in aquatic ecosystem . In view of this, our study aimed at investigating the toxicity potential of two typical organic compounds, and screening out novel photosynthetic indicators for the risk assessment of environmental pollutants. In this study, benzyl alcohol and 2-phenylethanol were chosen as the target organic compounds, and preliminary toxicity mechanism of these organic compounds on marine cyanobacterium Synechococcus sp. PCC7002 was investigated with chlorophyll fluorescence technology. Results showed that PCC7002 could be affected by benzyl alcohol or 2-phenylethanol stress, and the toxicity effect was concentration-dependent. And external benzyl alcohol and 2-phenylethanol stress damaged the oxygen evolving complex, and suppressed electron transport at the donor and receptor sides of photosystem II (PSII), influencing the absorption, transfer, and application of light energy. Furthermore, potential biomarkers were screened by half maximal inhibitory concentration (IC 50 ) on the basis of pearson correlation coefficient analysis, and fluorescence intensity difference between the I-step and P-step of OJIP curve (δF IP ) seems to be the most sensitive indicator for external stress. This study would be of significant interest to the biomarker community, and pave the way for the practical resource for marine pollution monitoring and assessment.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2022
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IF 4.326
Wen-Shuang Zhu,Dai Sun,Ling-Li Yu,Shao-Qi Zhi,Yu-Dong Shan,Yi-Fang Lu,Hai-Tao Ren,Song-Hai Wu,Yong Liu,Xu Han
In this study, Bi2.15WO6 with different morphologies was successfully synthesized and used for the selective photooxidation of benzyl alcohol to benzaldehyde in aqueous solutions. High conversion (85%) and selectivity (85%) can be simultaneously achieved under alkaline conditions by adding ethylenediamine to protect the produced benzaldehyde from overoxidation. In the oxidation process, ≡Bi–OO• and ≡Bi–OOH on Bi2.15WO6, instead of OH• and O2•–, are the primary oxidizing species to sequentially abstract two H (H+ + e–) from benzyl alcohol, accompanied by the formation of H2O2. Meanwhile, h+ and OH– also minorly contribute to the selective oxidation of benzyl alcohol via the H-abstraction pathway. This study enriches our understanding of the oxidizing species involved in the selective photooxidation of benzyl alcohol to benzaldehyde.
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JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
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2023
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IF 3.6
Shaodong Hu,Quan Zhao,Yapeng Niu,Canxuan Luo,Zhixuan Zhang,Bin He,Hui Hao
Biodegradable polymer materials are attractive in various biomedical applications. Herein, we report a block aliphatic copolymer, polycaprolactone-block-polyglycolide (PCL-b-PGA, denoted as PCLGA), and explored the polymer composition effect on the thermal and degradation behaviors. Three copolymers with different PCL/PGA weight ratios were obtained by a two-step ring opening polymerization. The chemical structures and compositions of copolymers were studied by NMR and FT-IR. The thermal behaviors were investigated by DSC and TGA. The in vitro degradation in phosphate buffer saline and in vivo degradation as an implant in rats were evaluated and the hygroscopic rate and polymer weight loss changes were monitored in an eight-week period. PCLGA with a higher PCL composition showed a slower degradation in vitro and in vivo. These PCLGAs with different degradation rates could be used as biomedical implants for potential application in drug delivery and tissue repair.
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PHYSICS OF FLUIDS
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2023
·Vol. 35
·期 1
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IF 4.6
Yuan Shuai,Zhou Mingyong,Liu Xijiang,Li Qiang,Drummer Dietmar,Jiang Bingyan
With the recent great interest in microfluidic devices, a better understanding of preconcentration technology has become increasingly important. Herein, concentration enrichment of charged samples is achieved by using field-amplified sample stacking (FASS) technology in the microchannel. This paper aims to develop a fundamental understanding of FASS and to propose a method to enhance the enrichment quality of FASS. First, numerical investigations are carried out to systematically study the effects of various parameters including the applied voltage, the charged properties of the sample, the buffer concentration ratio, the injection length, and the microchannel width on FASS enrichment performance. The results show that reducing the width of the microchannel is an effective way to improve the enrichment quality. The maximum enrichment ratio can be improved by 67.35% by reducing the width of the microchannel to less than 10 μ m due to the inhibition of background buffer diffusion. Second, to improve traditional FASS performance, a high-conductance gradient boundary is established by photoinitiating fabrication of a porous plug at the enriched interface position. This structure provides a region that reduces the local size of the internal channel to less than 5 μ m and has high flow resistance, but allows the electromigration of the charged analyte. Experimental results show that an electropherogram signal increases by a maximum factor of 329 in electrophoretic enrichment of fluorescein–Na with 5 × 10 −7 M initial concentrations, and the enrichment quality of traditional FASS is greatly improved.
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Plants-Basel
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2023
·Vol. 12
·期 2
·308
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IF 4.5
Ting Li,Xi Zhao,Xueli Cao
Prunus mumeis a traditional Chinese plant with high ornamental and application values due to its very early blooming and unique fragrance. Long-term breeding and cultivation have resulted in a variety ofP. mumeblossoms and have made their exploitation more possible. Existing studies on the volatile metabolome and aroma ofP. mumeblossoms are limited. In this study, six extensively planted cultivars ofP. mumeblossoms, including Gulihong (GLH), Yudie (YD), LvE (LE), Dongfang Zhusha (DFZS), Jiangmei (JM), and Gongfen (GF), were investigated for their differences in terms of volatile metabolome, as well as their aroma characteristics based on the strategies and methods of metabolomics. The volatile metabolites were analyzed using HS-SPME-GC-MS technique. A total of eighty-nine compounds were detected and sixty-five of them were tentatively identified, including thirty-seven phenylpropanoids/benzenes, seventeen fatty acid derivatives, ten terpenoids, and one other compound. YD contains the most volatile metabolites in terms of number and amounts, which impart more abundant aromas to this cultivar. Fifteen differential compounds were screened through the untargeted metabolic analysis of twenty-nine samples by principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA), while nine compounds were screened based on the odor activity value (OAV) analysis of the sixty-five identified compounds. GLH and GF, JM and LE were found to be more similar to each other based on chemometrics analysis of both volatile contents and OAVs, while YD and DFZS were markedly different from other cultivars. Six main metabolites, including benzaldehyde, methyl benzoate, benzyl acetate, eugenol, (E)-cinnamic alcohol, and 4-allylphenol, together with 2-nonenal, 3,4-dimethoxytoluene, and trans-β-Ionone were screened as differential compounds, owing to their higher contents and/or lower olfactory threshold, which endow an almond, cherry, phenolic, wintergreen, cananga odorata, floral, jasmine, hyacinth, cinnamon, clove, woody, medicinal, and violet fragrance to each variety, and greatly contribute to the aroma differences of six cultivars ofP. mumeblossom.Keywords:aroma;HS-SPME-GC-MS;Prunus mumeblossom;untargeted metabolomics;volatile metabolome
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DIAMOND AND RELATED MATERIALS
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2022
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IF 3.806
Shuchun Li,Yiling Ke,Xuefei Zhang,Shuchang Wu,Yiquan Chen,Zailai Xie
Nitrogen-doped carbon materials as metal-free catalysts have attracted considerable attention in selective oxidation of benzyl alcohol. However, the real active sites are still ambiguous due to complexities of surface functional groups and nitrogen species. Herein, a series of nitrogen-doped nanosheets with different N species content are simply fabricated, which exhibits excellent catalytic activity with 82–93 % conversion and 89–99 % selectivity in selective oxidation of benzyl alcohol into benzaldehyde. Moreover, it is demonstrated that the conversion of benzyl alcohol mainly depends on the hydroxyl functional groups, while both graphitic and pyridinic nitrogen are key factors to determine the selectivity of benzaldehyde. The present work demonstrates the structure-activity relationships between the catalytic performance for catalytic oxidation of benzyl alcohol and the surface functional groups of catalysts, paving the way for development of highly efficient nanocarbon catalysts.
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Processes
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2022
·Vol. 11
·期 1
·115
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IF 3.352
Ting Gao,Jingqi Lin,Ke Zhang,Mohsen Padervand,Yifan Zhang,Wei Zhang,Menglin Shi,Chuanyi Wang
Since conventional techniques are ineffective for NO removal at low concentrations, photocatalysis has become attractive in this regard, recently. However, in practice, photocatalytic NO removal has drawbacks such as limited light absorption and the proclivity of producing toxic by-products. To address these issues, novel defective Bi/Bi3NbO7structures with good porosity were fabricated by a solvothermal method and used for enhanced photocatalytic NO removal under visible light irradiation. The morphological and structural properties of the prepared materials were comprehensively analyzed. The optimal photocatalytic activity of pore-defective Bi/Bi3NbO7for NO removal was 60.3%, when the molar ratios of urea and Bi(NO)3•5H2O to pristine Bi3NbO7were 1:25 and 1:2, respectively, under the following operational conditions: NO concentration of 700 ppb, catalyst dosage of 50 mg and irradiation time of 14 min. The induced defects and the surface plasmon resonance (SPR) effect of Bi nanodots made remarkable contributions to improving the photocatalytic NO removal as well as inhibiting the toxic byproduct NO2. The photocatalytic NO removal pathway over the prepared photocatalysts was further mechanistically clarified taking advantage of EPR results and scavenging experiments. Considering the increased NO generation in the atmosphere, this work may provide novel insights for designing effective porous photocatalysts to treat gaseous toxic pollutants.Keywords:photocatalysis;Bi3NbO7;surface plasmon resonance;NO removal;defects
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EUROPEAN POLYMER JOURNAL
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2022
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IF 5.546
Kai-Xuan Qin,Shi-Si Li,Jing Xu,Zi-Long Li,Zi-Chen Li,Chunzu Cheng
Independence of food supply chain is a grand challenge encountered by the development of bio-based polymers. Here, we demonstrate the synthesis of amorphous aliphatic polyesters via organocatalyzed ring-opening polymerization of 9-membered lactone monomer, a novel downstream product of non-edible citronella oil. In particular, chemical transformation of trisubstituted alkene moiety owned by this renewable biomass was achieved by cross-metathesis of this bulky group with methyl acrylate . Three-armed star polymers were converted to free-standing films by UV-induced crosslinking. In particular, these crosslinked thin films could be efficiently recycled as ω -hydroxy ester upon methanolysis. This work opens a new avenue for the synthesis and application of terpene- and terpenoid-based polymers.
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MICROPOROUS AND MESOPOROUS MATERIALS
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2022
·
IF 5.876
Runjie Li,Yanyan Zhang,Bing Xing,Mengtian Huang,Ting Wang,Xiaoping Hong,Baocheng Zhou,Benxia Li,Jia Ding,Qi Sui
The selective oxidation of alcohols by transition-metal-based catalysts provides a green route for the production of aldehydes. In this paper, mesoporous SBA-15 supported bimetallic Ni x Co y oxides were synthesized for the catalytic oxidation of alcohol using oxygen as the sole oxidant. The catalytic activity was highly related to the metal composition, of which the Ni 1 Co 4 /SBA-15 catalyst showed the best catalytic performance with high benzyl alcohol conversion of 96.2% and benzaldehyde selectivity of 98.3%. It was proposed that the electronic structure of the Ni x Co y /SBA-15 catalysts can be modulated by Ni/Co ratio, and high Co 3+ /Co 2+ and Ni 3+ /Ni 2+ ratios promoted the catalyst activity. Compared to the Ni x Co y nanocatalysts obtained by removing SBA-15 support, the Ni x Co y /SBA-15 exhibited a better benzyl alcohol oxidation performance, suggesting a diffusion enhancement by the mesoporous structure of SBA-15 support.
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Agronomy-Basel
·
2023
·Vol. 13
·期 2
·339
·
IF 3.7
Jinjia Liu,Min Chen,Weihua Ma,Lifang Zheng,Bing Zhang,Huiting Zhao,Yusuo Jiang
Strawberries are popular fruits around the world, and their yield and fruit quality rely on pollination by honey bees and bumblebee colonies. Both bee species have their own advantages in strawberry pollination. This study investigates the characteristic of strawberry (Fragaria×ananassa‘Red Face’) flower volatiles and their effects on bee pollinators by (1) detecting the volatile compounds of strawberry flowers by polydimethylsiloxane (PDMS) combined gas chromatography-mass spectrometry (GC-MS), (2) determining whetherBombus terrestrisorApis melliferashowed antennae responses to certain compounds of strawberry flower volatiles by an electroantennography test (EAG), and (3) testing whether these compounds could elicit a corresponding behavioral response in bees. The results showed that (1) there were 38 chemical compounds in ‘Red Face’ volatiles with 7 types, most of which were known to be generally emitted by flowers but also have some compounds that have not been reported in strawberry flowers; (2)B. terrestrisandA. melliferahad strong EAG responses to several compounds, respectively, especially to ethyl benzoate, (Z)-3-hexenyl propionate, (Z)-3-hexenyl acetate, benzeneacetaldehyde and melonal; and (3) both bee species showed significant avoidance behaviors to four tested compounds, especially theB. terrestris. Flower volatiles of strawberry ‘Red face’ were different from other strawberry varieties that have been reported; some of these electrophysiologically active compounds could cause antennal potential responses in bees, as well as behavioral responses. Our study supports the idea that strawberry flower volatiles are one of the factors influencing bee foraging decisions and provides a reference for formulating more reasonable bee pollination to improve strawberry fruit quality.Keywords:strawberry flower volatiles;Bombus terrestris;Apis mellifera;EAG response;behavior response
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