Regenerative Biomaterials
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2024
·
IF 5.6
Sun Yage,Zhao Xinrui,Zhang Qian,Yang Rong,Liu Wenguang
The hypoxia microenvironment post myocardial infarction (MI) critically disturbs cellular metabolism and inflammation response, leading to scarce bioenergy supplying, prolonged inflammatory phase and high risk of cardiac fibrosis during cardiac restoration. Herein, an injectable hydrogel is prepared by Schiff-base reaction between fructose-1,6-bisphosphate (FBP)-grafted carboxymethyl chitosan (CF) and oxidized dextran (OD), following by loading fucoidan-coated baicalin (BA)-encapsulated zein nanoparticles (BFZ NPs), in which immunoregulatory and metabolism improving functions are integrally included. The grafted FBP serves to enhance glycolysis and provide more bioenergy for cardiomyocytes survival under hypoxia microenvironment, and elevating cellular antioxidant capacity via pentose phosphate pathway. OD with intrinsic anti-inflammatory effect can induce M2 polarization of macrophages to accelerate inflammatory elimination. While facing the possibility of endothelial-to-mesenchymal transition (EndoMT) caused by excessive expressed TGF-β1 secreted from M2 macrophages, BFZ NPs can target endothelia cells and intracellularly release BA to regulate the level of fatty acid oxidation, resulting in retained endothelial features and decreased risk of cardiac fibrosis. After being injecting the hydrogel into rats’ infarcted cardiac, the 28 day-post surgical outcomes demonstrate its benign effects on restoring cardiac functions and attenuating adverse left ventricular remodeling. This study shows a promising measure for MI treatment with immunoregulating and metabolism regulation comprehensively.
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PubMed
高影响因子
PROGRESS IN ORGANIC COATINGS
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2024
·
IF 6.5
Chao-Chen Cai,Juan Qin,Qing-Kai Zhu,Ting-Ting Li,Ching-Wen Lou,Jia-Horng Lin,Hai-Tao Ren
Superhydrophobic materials are currently undergoing rapid development in various industries, with increasing attention being paid to their service life. Herein, we report an all-weather self-healing superhydrophobic cotton fabric based on photothermal and Joule-heating effects, which can be used for efficient oil-water separation. With the assistance of Safranine T, unique cauliflower-like polypyrrole (PPy) was prepared. Subsequently, titanium nitride (TiN) was loaded to enhance the photothermal performance of the fabric, and polydimethylsiloxane (PDMS) was grafted onto surface to improve the water repellency of PPy@TiN/PDMS fabric. The fabric not only has strong light absorption in visible-near infrared region, but also has good Joule-heating effect, up to 116.3 °C (light intensity of 5 sun) and 128.5 °C (voltage of 8 V). Due to unique all-weather heating performance, the migration of low surface energy PDMS chains is accelerated, so that the PPy@TiN/PDMS fabric after air plasma etching and oxydation can quickly heal its water contact angle (WCA) to 156° under light or low voltage conditions. Additionally, the fabric demonstrates an outstanding performance for the separation of various oil-water mixtures and in multiple cycle separation experiments. This study presents a novel approach for extending the longevity of superhydrophobicity and addressing the issue of waste oil treatment.
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APPLIED SURFACE SCIENCE
·
2011
·
IF 1.795
Mengjia Yuan,Shengtian Wang,Xiaohong Wang,Lingling Zhao,Tianhong Hao
A new macroporous ZnO/MoO 3 /SiO 2 hybrid was synthesized by a method involving sol–gel technology and biomimetic synthesis. It was characterized by Elemental analysis, Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), X-ray photoelectron spectrum (XPS) and scanning electron microscopy (SEM). Chemical degradation of 0.3 g/L Safranin T (ST) by air oxidation over macroporous ZnO/MoO 3 /SiO 2 hybrid was studied. It was found that the decolorization efficiency and the chemical oxygen demand (COD) removal of ST reached above 95.3% and 93.2%, respectively, within 25 min at room temperature and atmospheric pressure. And the organic pollutant was mineralized to simple inorganic species such as HCO 3 − , Cl − and NO 3 − , while the total organic carbon (TOC) decreased 95.4%. The structure and morphology of the catalyst were still stable after six cycling runs and the leaching test showed negligible leaching effect.
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JOURNAL OF POLYMER RESEARCH
·
2025
·Vol. 32
·期 4
·1-13
·
IF 2.8
Lei Hengbo,Cao Xiang,Tang Yuguo
Monodisperse superparamagnetic poly (glycidyl methacrylate) microspheres (PGMA-HPG-COOH) with carboxyl group were synthesized and applied to treatment of cationic dyes wastewater. The composite adsorbent not only has good adsorption selectivity for cationic dyes (e.g., methylene blue (MB) and rhodamine 6G (R6G)), but also has convenient magnetic separation characteristics. The optimal pH for the adsorption of methylene blue was determined as pH 7, which was associated with the surface charge of adsorbent. Due to its ultra-high hydrophilicity, PGMA-HPG-COOH demonstrated a remarkably rapid adsorption rate for MB and R6G, and the adsorption saturation level of 95% can be achieved within just 10 min. The adsorption data showed nice correlation with pseudo-second-order kinetic model and Langmuir isotherm. The theoretical maximum adsorption capacity of PGMA-HPG-COOH for MB and R6G can reach 238.1 mg/g and 227.27 mg/g, respectively. Futhermore, PGMA-HPG-COOH can be effectively regenerated using a binary HCl-ethanol solution, maintaining the adsorption efficiency of 91.7% after five cycles of recycling. These findings substantiate the promising potential of the PGMA-HPG-COOH adsorbent for application in water treatment processes.
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Biomaterials Science
·
2025
·
IF 5.7
Ying Qi,Jing Zheng,Qian Zhang,Yage Sun,Jiaxing Shao,Hongying Wang,Rong Yang,Ziyang Xu,Chunyan Cui,Wenguang Liu
Chronic periodontitis is a long-standing thorny issue for oral health, characterized primarily by the excessive production and accumulation of reactive oxygen species, pathogenic bacterial infection, and the continuous loss of alveolar bone. In the present study, a poly(lipoic acid) (PolyLA) coenzyme-based tissue adhesive (PolyLA/Arg/Ga) was developed for the treatment of periodontitis. It functions by combining the nonantibiotic antimicrobial ion gallium ion (Ga3+ ) to resist pathogenic bacteria and promote osteogenesis; while the basic arginine not only stabilizes PolyLA at room temperature by forming salt bridge hydrogen bonds with its carboxyl groups but also serves as a cofactor, effectively regulating the release behavior of LA-based active molecules and Ga3+ by partially deprotonating the carboxyl groups on PolyLA. This, in turn, imparts significant antioxidant and antimicrobial properties to the adhesive. Thanks to the rich adhesive carboxyl groups on the surface of the adhesive and the structural stability of the hydrophobic PolyLA skeleton in a wet environment, The PolyLA/Arg/Ga exhibits long-lasting wet-resistant adhesion properties to biological tissues. Moreover, in vitro cell experiments and in vivo subcutaneous implantation studies demonstrate that the PolyLA/Arg/Ga adhesive has better cytocompatibility and histocompatibility. The PolyLA/Arg/Ga is explored as a tissue adhesive to treat a periodontitis model in rats.The results demonstrate that the PolyLA/Arg/Ga adhesive more effectively inhibited alveolar bone resorption and promoted periodontal tissue regeneration within 4 weeks compared to commercial patch. Thus, the simply designed yet multifunctional PolyLA/Arg/Ga bioadhesive offers an innovative approach for periodontitis management.
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
·
IF 5.4
Cuiru Wang,Xinyu Li,Wenhui Gu,Yisong Zhao,Tifeng Jiao
The composite Langmuir-Blodgett films of organic photovoltaic materials demonstrate unique advantages in the fields of photovoltaic devices, sensing, and chiral optics by fusing the functionality of organic materials with the orderliness of LB technology through precise assembly at the molecular scale. In this study, composite LB films of o-phenylphenoxyethyl acrylate (OPPEA) and bis-etherfluorene acrylate (A-BPEF) with Congo red (CR), methylene blue (MB), rhodamine B (RhB), and Saffron T (ST) dyes, respectively, have been successfully prepared by LB technology. The microstructure and optical properties of the composite films were systematically characterized by means of surface pressure-area isotherms (π-A curves), atomic force microscopy (AFM), transmission electron microscopy (TEM), contact angle measurements, and UV–visible spectroscopy, and the acid-base gas response and photoelectric conversion properties were investigated. The results show that different dye subphases significantly affect the molecular arrangement and microscopic morphology of the composite films, and the OPPEA/CR and A-BPEF/CR composite films exhibit significant response to HCl and NH 3 gases, while the OPPEA/RhB and A-BPEF/ST composite films show excellent photoelectric conversion efficiency and stability. This study provides a theoretical basis for the design and application of high-performance organic photovoltaic materials.
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Chenglong Yang,Shuqi Liu,Qiyue Zhao,Xinfan Zhang,Zhenggong Wang,Feng Zhang,Jian Jin
Organic solvent nanofiltration (OSN) membranes with precise molecular-sieving performance have become increasingly important in chemical and pharmaceutical industries, desiring superior membranes with both high permeability and selectivity. Herein, the V-shape Tröger's base (TB) structure is incorporated in the polyamide network to engineer microporosity as well as the molecular-sieving performance of the thin-film composite (TFC) polyamide membrane for organic solvent nanofiltration (OSN). The TFC membrane containing the TB structure features a rigid and contorted chain structure, which affords high and stable methanol permeability in OSN applications. Furthermore, the H-bond interaction between the H of amide groups and N in TB reinforces the interchain interaction, endowing the membrane with a precise selectivity to organic solutes. The as-prepared TFC membrane demonstrated high methanol permeance of 16.6 L m −2 h −1 bar −1 and sieving performance to organic molecules with molecular weight cut-off (MWCO) down to 349 Da. Furthermore, the membrane demonstrates shape selectivity for organic solutes, exploiting the fine microporous structure. This study may provide insights into the molecular design of TFC membranes by finely tuning the molecular features for precise solute separations.
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Polymers
·
2025
·Vol. 17
·期 11
·1493
·
IF 4.9
Na Meng,Jinxin Liu,Jialing Mi,Xuan Chen,Rong Rong,Junjie Hang,Zihan Jiang
In this study, polyethersulfone (PES)/sulfonated polyethersulfone (SPES) composite nanofiltration membranes doped with different contents of monolayer titanium carbide nanosheets (Ti3C2TX) were prepared by the nonsolvent induced phase inversion (NIPS) method. The effects of Ti3C2TXon membrane structure, separation performance and antibacterial activity were investigated systematically. The results demonstrated that the viscosity of the casting solution increased significantly with the increasing content of Ti3C2TX. In addition, the pore size of the membrane surface first decreased and then increased; porosity and hydrophilicity were optimized synchronously; and the density of negative charges on the surface increased. The M2 membrane showed a rejection rate of more than 90% for Metanil yellow (MY) and methylene blue (MEB). The order of salt ion rejection rates was magnesium sulfate (MgSO4) > sodium sulfate (Na2SO4) > sodium chloride (NaCl), and water flux reached the peak (18.5 L/m2·h·bar). The antibacterial activity of the M2 membrane was significantly enhanced, and its antibacterial rate againstBacillus subtilisincreased from 15% (M0) to 58%. This phenomenon was attributed to the synergistic mechanism of the Ti3C2TXphysical capture effect, reactive oxygen species (ROS) generation and sharp edge damage to bacterial cell membranes. This study provides theoretical support and a technical path for the development of MXene composite membranes with high separation efficiency and excellent antibacterial properties.
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CELLULOSE
·
2025
·
IF 4.8
Huang Xin,Ganie Showkat Ali,Rather Luqman Jameel,Mir Shazia Shaheen,Assiri Mohammed A.,Mady Mohamed F.,Li Qing
The incorporation of antimicrobial functionalities into cellulose represents a significant advancement in biopolymer modification, enhancing its potential applications in biomedical and food sectors. In this study, we synthesized and characterized quaternary ammonium-functionalized cellulose (Q-Cell) and its intermediates, employing a three-step modification strategy (tosylation, amination, and quaternization). Structural and functional attributes of the derivatives were elucidated using SEM, TGA, FT-IR, and NMR ( 1 H and 13 C) spectroscopy. The optimized synthesis under an aqueous alkaline medium (H₂O/NaOH/triethylamine) at 5 °C for 5 h enabled selective functionalization while preserving the cellulose backbone integrity. A thorough assessment of the structural characterization and stability of the components revealed that the modified cellulose demonstrated superior antibacterial and antioxidant properties accompanied with enhanced thermal properties. The antimicrobial assessment revealed 100% inhibition of E. coli and S. aureus at 250 µg/L with MIC values of 4 and 8 µg/mL, respectively. Additionally, Q-Cell exhibited superior free radical-scavenging ability in superoxide, hydroxyl, and DPPH assays, attributed to electrostatic stabilization of radicals and charge-assisted hydrogen transfer mechanisms. These findings suggest that Q-Cell is a promising candidate for antimicrobial and antioxidant applications in biomedical, pharmaceutical, and food packaging industries.
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PROGRESS IN ORGANIC COATINGS
·
2025
·
IF 7.3
Baolong Xue,Xuejing Liu,Yuying Liu,Qibin Xu,Junfeng Ke,Mengjin Jiang
Flexographic printing plates, which are typically composed of a metal substrate, an adhesive layer, and a poly(vinyl alcohol) (PVA) photosensitive layer, are essential for achieving high-resolution patterns in flexographic printing technology. The adhesive layer, serving as the bonding interface between the metal and PVA layers, must exhibit strong adhesion to both metal and polymer surfaces, along with high toughness, mechanical strength, solvent resistance, and durable adhesion to meet the mechanical and chemical requirements of flexographic printing technology. Herein, inspired by the structure of mussel foot silk protein, this study integrates carbon–carbon double bonds, catechol, alcohol hydroxyl, and amino ester groups into a single polymer chain via a two-step reaction. Benefits to its rigid-flexible cross-linked network, the obtained adhesive exhibits good strength, modulus, and toughness. Specifically, its tensile strength, tensile modulus, elongation at break, and impact strength are 1.70 MPa, 0.85 GPa, 19.3 %, and 2.97 kJ/m 2 , respectively. Furthermore, the adhesive achieves a 180° peel strength of 2.26 N/mm with tinplate and 3.89 N/mm with flexographic printing plates. Notably, after 7 days of immersion in water, ethanol, and dimethylformamide, the 180° peel strength retention rate was as high as 96.9 %, 96.2 %, and 93.9 %, respectively. After being stored at room temperature for 28 days, the 180° peel strength retention rate reaches up to 98.3 %, highlighting its long-lasting durability. This mussel-inspired group integration strategy provides a straightforward and efficient approach for developing high-performance multi-functional adhesives, with significant potential for advancing flexographic printing.
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Nano Today
·
2025
·
IF 10.9
Xinrui Zhao,Rong Yang,Yage Sun,Wenguang Liu
Abnormal neuronal discharge due to disordered neurotransmitter homeostasis and harsh inflammation in epileptic focus is prone to cause recurrent seizures. However, current difficulties in drug delivery across blood-brain barrier (BBB) and regulation of complex pathological microenvironment hinder complete control of epilepsy with clinical therapies. Herein, a novel microenvironment-responsive drug-loaded polyelectrolyte nanocomplex (HCT-Fu@VB 6 ) formed by electrostatic self-assembly between tryptophan-modified hydroxypropyl chitosan (HCT) and fucoidan (Fu) with efficient vitamin B 6 (VB 6 ) loading, is developed for potent epilepsy treating, innovatively aiming to modulate neurotransmitters balance and attenuate the neuroinflammatory responses. Specifically, HCT confers the nanoparticles with specific binding affinity towards L-type amino acid transporter 1 expressed on brain endothelial cells, thereby significantly contributing to enhanced trans-BBB drug delivery efficiency. The fucoidan-containing polyelectrolyte nanocomplexes serve to provide intrinsic antioxidant property. Notably, the prepared polyelectrolyte nanocomplexes are dissociated in response to the mimic pathological neuronal discharges due to disturbed electrostatic equilibrium, facilitating accelerated VB 6 release for enhanced oxidative stress mitigation and effective neurotransmitter homeostasis modulation, acting as a competitive antagonist of ATP-gated purinergic P2RX7. The developed HCT-Fu@VB 6 nanoparticles demonstrate significant therapeutic efficacy as an electrically responsive trans-BBB drug delivery system, remarkably reducing seizure in epileptic rats while maintaining an excellent safety profile.
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高影响因子
Materials Today Communications
·
2024
·
IF 3.7
Hong-Bei He,Chao-Chen Cai,Qing-Kai Zhu,Ting-Ting Li,Ching-Wen Lou,Jia-Horng Lin,Hai-Tao Ren
Superhydrophobic surfaces with rapid self-healing ability are ideal for long-life superhydrophobic materials. The micro-nano rough structure has great influence on the superhydrophobicity, and the micro-dissolution cotton fabric can realize the stable load of nanoparticles. In this regard, we prepared multifunctional fabrics with an all-weather self-healing superhydrophobic layer and photocatalytic self-cleaning properties by spraying TiN and TiO 2 on micro-dissolution-treated polypyrrole/cotton fabrics. The results show that the modified fabrics maintain superhydrophobicity even in harsh environments (water contact angle (WCA) up to 160.0°, water sliding angle (WSA) as low as 3.9°), with excellent abrasion resistance and stability. Even after the fabric loses superhydrophobicity due to ion etching, the superhydrophobicity can be quickly restored by photothermal or electrothermal treatment in 13 min. At the same time, the prepared multifunctional fabrics have hydrophobic and oleophilic properties, and possess good oil-water separation efficiency (98.8 %). After being contaminated by oil, the WCA recovers from 135.0° to 160.0° via the photocatalytic property of the fabric. In addition, the fabrics exhibit excellent de-icing effects. This research provides new opportunities to extend the life of superhydrophobic textiles with all-weather self-healing properties.
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高影响因子
危险品化学品经营许可证（带存储）