JOURNAL OF PEPTIDE SCIENCE
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2023
·Vol. 29
·期 11
·e3497
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IF 2.1
Ruifang Li,Pu Hao,Kedong Yin,Qingpeng Xu,Shiming Ren,Yingyuan Zhao,Lan Zhang,Beibei Zhang
Antimicrobial peptides and their analogues have become substitutes for antibiotics in recent years. The antimicrobial peptide analogue SAMP-A4-C8 ( n -octanoic-VRLLRRRI) with high antimicrobial activity was found in our lab. We speculate that it may kill pathogens by some lethal mechanism of action. In the present investigation, the microbicidal activities of SAMP-A4-C8 and its mechanism of action were investigated. The results demonstrated that SAMP-A4-C8 had lethal activities against Staphylococcus aureus and Candida albicans by cell disruption. Based on its microbicidal activities, we believe that it is worth further research for its potential as drug candidate. The results showed that SAMP-A4-C8, with low propensity to induce the resistance of S. aureus and C. albicans , could kill the persister cells of S. aureus and C. albicans , exhibited biofilm forming inhibition activity and preformed biofilm eradication ability against S. aureus and C. albicans , and displayed therapeutic potential on pneumonia in S. aureus -infected mice by reducing lung inflammation. The present study provided a promising drug candidate in the war against multidrug resistance.
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Food Chemistry-X
·
2023
·
IF 6.1
Min Wang,Luyao Zhao,Yu Niu,Shu Qin,Lixin Zhang,Liyan Jia,Xu Jing
In this study, a magnetic deep eutectic solvent coupled with dispersive liquid–liquid microextraction using high-performance liquid chromatography (MDES-DLLME-HPLC) was developed to detect strobilurin fungicides. The green hydrophobic MDES synthesized by methyltrioctylammonium chloride, ferric chloride, and heptanoic acid was used as an extraction solvent, which was dispersed by vortex and separated by an external magnetic field. The use of toxic solvents was avoided, and the separation time was reduced. The best experimental results were obtained through single factor and response surface optimization. The method had a good linear relationship with R 2 > 0.996. The limit of detection (LOD) ranged from 0.001 to 0.002 mg L −1 . The extraction recoveries were 81.9–108.9%. The proposed method was rapid and green, and it has been successfully applied to detection of strobilurin fungicides in water, juice, and vinegar.
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INORGANIC CHEMISTRY
·
2023
·
IF 4.6
Xiaolin Zhu,Zhangcheng Pan,Tianyue Xu,Xiuwen Shao,Zhaoju Gao,Qingyu Xie,Yupeng Ying,Wei Pei,Hao Lin,Jia Wang,Xiaosheng Tang,Weiwei Chen,Yongfeng Liu
All-inorganic perovskite quantum dots (PeQDs) have sparked extensive research focus on white-light-emitting diodes (WLEDs), but stability and photoluminescence efficiency issues are still remain obstacles impeding their practical application. Here, we reported a facile one-step method to synthesize CsPbBr3 PeQDs at room temperature using branched didodecyldimethylammonium fluoride (DDAF) and short-chain-length octanoic acid as capping ligands. The obtained CsPbBr3 PeQDs have a near-unity photoluminescence quantum yield of 97% due to the effective passivation of DDAF. More importantly, they exhibit much improved stability against air, heat, and polar solvents, maintaining >70% of initial PL intensity. Making use of these excellent optoelectronic properties, WLEDs based on CsPbBr3 PeQDs, CsPbBr1.2I1.8 PeQDs, and blue LEDs were fabricated, which show a color gamut of 122.7% of the National Television System Committee standard, a luminous efficacy of 17.1 lm/W, with a color temperature of 5890 K, and CIE coordinates of (0.32, 0.35). These results indicate that the CsPbBr3 PeQDs have great practical potential in wide-color-gamut displays.
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PEST MANAGEMENT SCIENCE
·
2023
·Vol. 79
·期 9
·3090-3102
·
IF 4.1
Jinlan Xin,Kangle Jia,Longfei Yu,Huanling Li,Junhua Ning,Xiaoshan Zheng,Haifu Wu,Xingxing Liu,Linjia Huang,Wu Wen
Background Efficient deposition of high-speed droplets on superhydrophobic leaf surfaces remains an important challenge. For anisotropic wired superhydrophobic leaf surfaces, the splashing phenomenon is especially serious because it leads to the low effective utilization of pesticides by biological targets. The lost pesticides cause serious ecological environment pollution, therefore there is an urgent need to develop a green and sustainable cost-effective strategy to achieve efficient deposition of high-speed droplets on anisotropic superhydrophobic leaf surfaces at low dosage. Results One type of green pseudogemini surfactant is constructed based on fatty acids and hexamethylenediamine by electrostatic interaction to control the splashing and spreading of high-speed droplets on superhydrophobic surfaces. The formed surfactant can not only achieve complete inhibition of the bouncing of droplets, but also promote rapid spreading on superhydrophobic leaf surfaces at very low usage. The efficient deposition and superspreading phenomenon are attributed to the rapid migration and adsorption of the surfactant from the dynamic spherical micelles at the newly formed solid–liquid interface, the network-like aggregated spherical micelles, and the Marangoni effect caused by the surface tension gradient. Moreover, the surfactant shows an excellent synergistic effect with herbicides to control weeds by inhibiting droplet splashing. Conclusion This work provides a simpler, more effective and sustainable approach to utilize aggregated spherical micelles rather than conventional vesicles or wormlike micelles to improve the droplet deposition on superhydrophobic leaf surfaces and reduce the impact of surfactants and pesticides on the ecological environment. © 2023 Society of Chemical Industry.
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JOURNAL OF CHROMATOGRAPHY A
·
2022
·
IF 4.601
Huazi Wang,Tiantian Wang,MingXiu Hong,Ziyang Wang,Xiaoyan Jin,Hai Wu
This study describes the development of a fully manual method for on-site dispersive liquid-liquid microextraction based on the direct solidification of switchable-hydrophilicity salicylic acid (on-site DLLME-DSSA) coupled with high-performance liquid chromatography with an ultraviolet detector (HPLC-UVD) and its utilization for the detection of benzoylurea insecticides (BUs) in water and honey samples. Salicylic acid (SA), a switchable hydrophilic aromatic acid, was used as an extraction solvent. It can be converted into the hydrophobic/hydrophilic forms in pH-changeable solutions, facilitating facile and effective dispersion and phase separation. Moreover, the melting point of SA (significantly higher than room temperature) enables its direct solidification without an ice-water bath, facilitating its collection by filtration. The dispersion, separation, and collection of the extraction solvent were carried out entirely in a plastic syringe without requiring special apparatus or additional energy. Univariate and response surface analyses were used to optimize various parameters of the on-site DLLME-DSSA method. Under optimal conditions, the limits of determination (LODs) were 1.50 µg L −1 and 0.03–0.09 mg kg −1 in water and honey, respectively. The relative standard deviations (RSDs) for inter-day ( n = 5) and intra-day ( n = 5) precision were ≤8.4%, whereas the extraction recoveries and enrichment factors for the BUs ranged from 67.0 to 97.1% and 29 to 34, respectively. Furthermore, the proposed method was used for the on-site extraction and laboratory detection of BUs from real water and honey samples. Theoretical analyses indicated non-covalent interactions (such as hydrogen bonds, electrostatic interactions, van der Waals forces, and π-π interactions) to be the main driving force for extraction. This study introduces a switchable hydrophilic aromatic acid capable of direct solidification into on-site DLLME for the first time, opening new frontiers in the development of on-site sample pretreatment methods.
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ANALYTICA CHIMICA ACTA
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2022
·
IF 6.911
Ang Li,Song Xue,Yu Xu,Sihui Ding,Di Wen,Qi Zhang
A critical challenge in using deep eutectic solvents (DESs) in capillary electrophoresis (CE) is to develop separation systems in which a DES can really work as a single entity. To achieve this, the authors recently demonstrated a novel strategy that takes advantage of the aqueous dispersibility of hydrophobic DESs (or more accurately hydrophobic eutectic solvents (HESs)). However, the previous work was limited only to the separation of achiral analytes, e.g., analogues, homologues, and isomers. The present study was designed as a follow-up study in order to explore the feasibility of employing HES-type pseudo-stationary phases (PSPs) in CE for chiral separations . By using carboxymethyl-β-cyclodextrin (CM-β-CD) as a model chiral selector, we provide the first evidence that there is a potential synergistic effect between HESs and traditional chiral selectors. Specifically, the combined use of HES (−)-menthol:octanoic acid and CM-β-CD allowed excellent enantioseparations of several basic drugs which were not able to be resolved in the single CM-β-CD system. The enantioresolutions were significantly improved while the migration times of the enantiomers were also shortened due to the hydrophobic mechanism of the HES-type PSP. Critical factors influencing the novel chiral CE system were systematically investigated. Since HESs are considered as “designer” solvents with highly tunable properties, this study demonstrates the potential of employing HESs (or HDES)-type PSPs in CE for chiral separations .
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Analytical Methods
·
2022
·Vol. 15
·期 5
·648-654
·
IF 3.532
Luyao Zhao,Min Wang,Jiadong Wang,Jing Wu,Zhuoting Zhang,Xu Jing,Xiaowen Wang
A detection method of carbofuran (CBF) in water samples was reported using deep eutectic solvent (DES)-based dispersive liquid–liquid microextraction (DLLME) combined with digital image colorimetry (DIC), which was environmentally friendly, solvent-saving, rapid, and convenient. Under alkaline conditions, the green and multifunctional extractant DESs dissociated into linalool and heptanoic acid, and CBF was hydrolyzed to 2,3-dihydro-2,2-dimethyl-7-benzofuranol and further coupled with fast blue BB salt to form an azo derivative. Heptanoic acid led to the dispersion of linalool to extract the orange-red azo derivative; DIC was used for quantitative analysis using a smartphone with its associated ease of data-acquisition. This experiment optimized the types, molar ratios, and volumes of DESs and the amounts of sodium carbonate and sodium chloride. Under optimal conditions, the limits of detection (LOD) and quantitation (LOQ) were 0.024–0.032 mg L−1 and 0.081–0.108 mg L−1, respectively. The extraction recoveries in real samples (tap, pond, and river water) were 92.4–101.0% with a relative standard deviation below 4.6%. This method has successfully analyzed CBF in different water samples and shows prospects for the monitoring and control of CBF residues in other environmental samples.
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APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Qingkai Zheng,Muhammad Chhattal,Changning Bai,Zhiwen Zheng,Dan Qiao,Zhenbin Gong,Junyan Zhang
Polytetrafluoroethylene (PTFE) is in the limelight due to its self-lubricating properties and outstanding corrosion resistance. Nevertheless, it suffers from severe adhesive and abrasive wear, resulting in barriers to the achievement of robust superlubricity and reliability of moving parts. Herein, two green protic ionic liquids (ILs) are synthesized using alkyl amine and carboxylic acids with long molecular chains, which are applied in PTFE/steel tribo-pair, showing a robust superlubricity under high contact pressure. Compared with conventional lubricating oils (PAO8, PAO10 and PEG400), as-prepared ILs show the lowest coefficients of friction less than 0.008, and the lowest wear volume of PTFE with the adhesive and abrasive wear of PTFE significantly inhibited. The excellent lubricating performance attributes to the thick and dense Stern layer as well as the formation of tribo-chemical film. This work, for the first time, achieves superlubricity on soft material substrates and guides the lubricants design for PTFE tribological applications.
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FOOD CHEMISTRY
·
2023
·
IF 8.8
Jingyu Zhang,Zhihui Zhang,Liping Yao,Mingrong Qian,Zuguang Li,Yulin Han,Shanshan Bai,Mawrong Lee
The existing QuEChERS-combined analytical pretreatment methods are limited by large reagent consumption, high environmental burden, and mediocre effects. To provide an efficient and green pretreatment method, this study developed pH-responsive switchable deep eutectic solvents (SDESs) to extract triazole fungicides (TFs) from fruit peel wastes, which could enhance the preconcentration effect of target compounds in food waste samples with complex matrices. The mechanisms of pH-induced phase transition and hydrophobicity-hydrophilicity conversion of pH-responsive SDESs were investigated by pH phase diagrams and chemical characterization techniques, respectively. We validated the established method by high-performance liquid chromatography-diode array detector (HPLC-DAD), and lower LOD (0.089–0.351 ng mL −1 ), LOQ (0.297–1.172 ng mL −1 ), RSD (≤8.8 %) and satisfactory recoveries (90.6 %-110.9 %) and preconcentration factors (389–512) were obtained in rotting grape peel, watermelon peel, and orange peel samples. Our findings highlight the potential of pH-responsive SDESs in the extraction and analysis of various natural food products.
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SCIENCE OF THE TOTAL ENVIRONMENT
·
2022
·
IF 10.753
Xiaoyi Chen,Sameer Hussain,Yuhai Tang,Xi Chen,Sijie Zhang,Yue Wang,Pei Zhang,Ruixia Gao,Sicen Wang,Yi Hao
Continuous emergence of persistent organic pollutants perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) in various water bodies around the world poses a serious threat to the global ecosystem. The exploration of advanced detection/removal techniques to monitor/treat such type of toxicants is urgently required. Herein, we unveiled a donor-acceptor type conjugated polymer PF-DBT-Im as a first-of-its-kind ratiometric fluorescent probe for visual, amplified, and specific monitoring of PFOA and PFOS with ultra-low detection limits of 6.12 nM (PFOA) and 14.3 nM (PFOS), respectively. PF-DBT-Im undergoes strong aggregation after binding with PFOA/PFOS as evident by transmission electron microscopy , zeta potential measurements, and dynamic light scattering studies. This promotes interchain Förster resonance energy transfer process to endorse an obvious emission color change from blue-to-magenta under ultraviolet lamp excitation. Consequently, a smartphone-integrated portable device is fabricated for realizing rapid and on-site detection of PFOA/PFOS. Besides, a new class of magnetic adsorbent Fe 3 O 4 @NH 2 &F 13 is also prepared and used in combination with PF-DBT-Im to remove PFOA/PFOS from the environmental water effectively and rapidly as confirmed by liquid chromatography-mass spectrometry analysis. Thus, utilizing the excellent signal amplification property of PF-DBT-Im and the remarkable magnetic separation capability of Fe 3 O 4 @NH 2 &F 13 , a multifunctional system is developed for step-wise recognition and separation of PFOA/PFOS from the environmental water proficiently and rapidly.
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CHEMICAL ENGINEERING JOURNAL
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2023
·
IF 15.1
Zi-Hui Cai,Jian-Dong Wang,Lin Liu,Liu-Ding Ruan,Qi Gu,Xin-Yu Yan,Li-Na Fu,Peng-Quan Zhao,Su Zhang,Yu-Jie Fu
A green, novel and designable natural deep eutectic solvent-based supramolecular solvents/equilibrium solution (NADES-SUPRAS/EqS) was developed, which possesses better stability and free designability with a wider range of synthesis while compared to the typical alkyl carboxylic acid-based SUPRAS. The physicochemical properties and specific synthesis patterns of NADES-SUPRAS/EqS had been investigated. In addition, a more intelligent solvent regulated synthesis system had been developed to prepare corresponding supramolecular systems according to different polarity target phytochemicals through tailoring the components of synthetic NADES-SUPRAS/EqS. During the NADES-SUPRAS extraction of Zanthoxylum bungeanum Maxim. leaves (ZBML), 18 kinds of NADES were screened and the proportion of NADES as well as the ethanol content were varied tailor. After tailoring, all of the extracted chlorogenic acid, neochlorogenic acid, rutin, as well as 91.775 % of hyperin, 94.940 % isoquercetin and 84.405 % quercetin were distributed in the EqS phase while all of the hydroxy-α-sanshool (HAS) were distributed in the NADES-SUPRAS phase. Furthermore, NADES-SUPRAS/EqS extraction rate reached 9.741 mg/g, which were 7.604-fold, 2.352-fold, 1.141-fold, and 1.384-fold to that of water, ethanol, 70 % ethanol and methanol extraction, respectively. The excellent extraction and separation effects were due to the large number of hydrogen bonds and hydrophobic forces. Dynamic multi-stage countercurrent extraction combined with water and macroporous resin recovery enabled significant cost reductions and rapid recovery of chemical components and solvents. This novel solvent could be intelligently designed and be of great significance for the extraction of different polarity phytochemicals from plants.
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MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Ruiyu Fu,Tingze Ren,Yanhui Zhang,Xiaoli Guo,Xin Di
This paper describes a sensitive, simple and green analytical method for pretreatment of sulfonylurea and pyrethroid herbicides in water samples by supramolecular solvent-based liquid phase microextraction (SUPRAS-LPME). The SUPRAS was rapidly formed by nonanoic acid and tetrahydrofuran (THF)/water solution. The attractive features of SUPRAS-LPME include the simplicity, high enrichment factor, low cost and less consumption of organic solvents. The main influencing factors including type and volume of fatty acids, volume of THF , ionic strength, vortex time and volume of formic acid were optimized in detail, and then the significant variables were optimized by Box-Behnken design (BBD). Under the optimized condition, the proposed method shows high precision (RSDs < 13.7 %), low limits of detection (0.5–10 μg L -1 ) and limits of quantitation (10–45 μg L -1 ), acceptable recovery (71.3 %-95.9 %). The proposed method was successfully applied for analysis of sulfonylurea and pyrethroid herbicides in water samples, making it an alternative analytical strategy for determination of trace analytes at the microgram per liter range with desirable sensitivity.
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