INDUSTRIAL CROPS AND PRODUCTS
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2025
·
IF 6.2
Jingang Yao,Guohui Zhang,Guanyi Chen,Beibei Yan,Xin Su,Dongmei Bi,Guiying Xu,Ke Yang,Yan Yao
Bio-oil, deriving from sustainable biomass pyrolysis, presents significant promise as a source for the production of renewable low-carbon alcohols (C 1–4 alcohols). Nevertheless, the intricate composition of bio-oil necessitates research into more eco-friendly and efficient conversion methodologies. In this context, an innovative and sustainable approach utilizing titanium dioxide (TiO 2 ) as a catalyst has been successfully devised and implemented for photocatalytic conversion of bio-oil into methanol-enriched C 1–4 alcohols under mild conditions. The TiO 2 catalyst has undergone a comprehensive characterization, unveiling its remarkable crystallinity, mesoporous structure and outstanding optical absorption properties. Significantly, at ambient temperature, employing a TiO 2 catalyst loading of 4 wt%, a reaction duration of 3 h and an ethanol-to-bio-oil molar ratio of 12:1, TiO 2 demonstrated an exceptional selectivity of 66.24 % for C 1–4 alcohols, with particular emphasis on a methanol selectivity of 38.96 %. This stands in stark contrast to the control groups, one of which lacks ethanol (resulting in selectivities of 2.18 % and 0.57 %, respectively), and the other lacks bio-oil (resulting in selectivities of 0 % and 0 %, respectively). Impressively, the overall alcohol selectivity reached a remarkable 68.79 %. Even after undergoing 5 reuse cycles, TiO 2 continued to exhibit remarkable photocatalytic activity, maintaining methanol selectivity at 33.56 % and alcohol selectivity at 48.88 %. Additionally, the photocatalytic mechanism of bio-oil over TiO 2 has been reasonably theorized. The results highlight the potential of TiO 2 photocatalytic conversion of bio-oil to produce C 1–4 alcohols rich in methanol.
研究领域:
能源科学
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环境科学
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化学工程
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DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2011
·
IF 2.089
Hengde Li,Tianfei Zhang,Weiqin Fu,Kazuhiro Tamura
Liquid–liquid equilibrium (LLE) data of the binodal curves and tie-line compositions were examined for ternary mixtures of (water + methanol + geraniol) and (water + ethanol + geraniol) at T = (283.15, 298.15, and 313.15) K. The immiscible area of the (water + methanol + geraniol) system is wider than that for the ethanol system at the same temperature. The experimental liquid–liquid equilibrium data have been represented by using the original UNIQUAC, extended UNIQUAC, and modified UNIQUAC models.
研究领域:
化学工程
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物理化学
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产品关联
DOI
高影响因子
MOLECULES
·
2019
·Vol. 24
·期 10
·1881
·
IF 3.06
Geng Zhao,Ming Liu,Xinkui Xia,Li Li,Bayin Xu
In this study, a carbon-based solid acid was created through the sulfonation of carbon obtained from the hydrothermal pretreatment of glucose. Additionally, ethyl levulinate, a viable liquid biofuel, was produced from furfuryl alcohol using the environmentally benign and low-cost catalyst in ethanol. Studies for optimizing the reaction conditions, such as reaction time, temperature, and catalyst loading, were performed. Under the optimal conditions, a maximum ethyl levulinate yield of 67.1% was obtained. The recovered catalyst activity (Ethyl levulinate yield 57.3%) remained high after being used four times, and it was easily regenerated with a simple sulfonation process. Moreover, the catalyst was characterized using FT-IR, XRD, SEM, elemental analysis, and acid-base titration techniques.Keywords:furfuryl alcohol;ethanol;ethyl levulinate;carbon-based solid acid
研究领域:
化学工程
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可再生资源与环境科学
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DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
·
2020
·
IF 2.888
Xiaoxing Lu,Shaoxia Xie,Jiayi Zhang,Qunfang Lei,Wenjun Fang
Density, viscosity and electrical conductivity are measured for the methanol and ethanol solutions of the ionic liquid (IL), 2,2-diethyl-1,1,3,3-tetramethylguanidinium bis(trifluoromethylsulfonyl)imide ([TMG(C 2 ) 2 ][NTf 2 ]), at the molality up to 3 mol·kg −1 , and the interactions are explored at the molecular level. The concentration dependence of the physicochemical properties is evaluated by empirical models including the Redlich–Kister, the Jones–Dole and the Casteel–Amis equations. The obtained interaction coefficients from viscosity measurements indicate the structure making effect in both systems, by which alcohol molecules gather around the ionic moieties through significant ion–dipole interactions. According to the calculated apparent molar volume and molar conductivity, ion aggregation occurs to form ion pairs when a specific concentration ( c 0 ) is reached. The IL behaves as a weak electrolyte in alcohols, and ethanol is more efficient to dissociate IL with a higher value of c 0 .
研究领域:
物理化学
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分子相互作用
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DOI
高影响因子
Biotechnology for Biofuels
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2017
·Vol. 10
·期 1
·1-16
·
IF 5.203
Jiang Yongguang,Xiao Peng,Shao Qing,Qin Huan,Hu Zhangli,Lei Anping,Wang Jiangxin
Background Microalgae have been demonstrated to be among the most promising phototrophic species for producing renewable biofuels and chemicals. Ethanol and butanol are clean energy sources with good chemical and physical properties as alternatives to gasoline. However, biosynthesis of these two biofuels has not been achieved due to low tolerance of algal cells to ethanol or butanol. Results With an eye to circumventing these problems in the future and engineering the robust alcohol-producing microalgal hosts, we investigated the metabolic responses of the model green alga Chlamydomonas reinhardtii to ethanol and butanol. Using a quantitative proteomics approach with iTRAQ-LC–MS/MS technologies, we detected the levels of 3077 proteins; 827 and 730 of which were differentially regulated by ethanol and butanol, respectively, at three time points. In particular, 41 and 59 proteins were consistently regulated during at least two sampling times. Multiple metabolic processes were affected by ethanol or butanol, and various stress-related proteins, transporters, cytoskeletal proteins, and regulators were induced as the major protection mechanisms against toxicity of the organic solvents. The most highly upregulated butanol response protein was Cre.770 peroxidase. Conclusions The study is the first comprehensive view of the metabolic mechanisms employed by C. reinhardtii to defend against ethanol or butanol toxicity. Moreover, the proteomic analysis provides a resource for investigating potential gene targets for engineering microalgae to achieve efficient biofuel production.
研究领域:
生物化学
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植物学
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能源生物学
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DOI
PubMed
高影响因子
Nanoscale
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2019
·Vol. 11
·期 39
·18176-18182
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IF 6.97
Cheng Wang,Hui Xu,Fei Gao,Yangping Zhang,Tongxin Song,Caiqin Wang,Hongyuan Shang,Xing Zhu,Yukou Du
Developing cost-effective catalysts with superb activity and stability to alcohol electro-oxidation is a decisive factor towards the progress of direct alcohol fuel cells (DAFCs). Rationally utilizing the architectural and surface microstructural sensitivity of nanocatalysts can significantly increase their electrocatalytic properties. Here, we report an appropriate route that allows the fabrication of ultrafine PtFeSn nanowires (NWs) with tunable compositions. Interestingly, the addition of Sn reconstructed the surface microstructures, making ultrafine 1D NWs rich in a large number of surface protuberances, which may facilitate the oxidation of ethanol and methanol. Impressively, further catalytic studies demonstrate that all the PtFeSn NWs exhibit excellent catalytic capabilities for ethanol oxidation reaction (EOR) and methanol oxidation reaction (MOR), and display composition-related electrocatalytic activity with Pt1Fe0.20Sn0.46 NWs, possessing the highest activity for EOR and MOR. In addition, the trimetallic PtFeSn NWs exhibit significant meliorative durability relative to PtFe NWs and commercial Pt/C. The superb electrocatalytic performance is ascribed to its one-dimensional (1D) structure, atomic-level fine diameter, synergistic effect among Pt, Fe, and Sn components and abundant protuberances on the surface. Thus, this study highlights the significance of accurate structure- and surface-controlled Pt-based NWs for electrocatalysis and provides a universal approach for designing multi-component catalysts.
研究领域:
材料科学
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电化学
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纳米技术
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催化
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DOI
PubMed
高影响因子
TREE PHYSIOLOGY
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2017
·Vol. 37
·期 12
·1659-1671
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IF 3.653
Yu Chunna,Guo Hong,Zhang Yangyang,Song Yaobin,Pi Erxu,Yu Chenliang,Zhang Lei,Dong Ming,Zheng Bingsong,Wang Huizhong,Shen Chenjia
Taxol is currently a valuable anticancer drug; however, the accumulated mixture of taxoids can vary greatly among Taxus species. So far, there is very little genomic information for the genus Taxus, except for Taxus baccata. Transcriptome analysis is a powerful approach to explore the different regulatory mechanisms underlying the taxoid biosynthesis pathway in Taxus species. First, we quantified the variation in the taxoid contents between Taxus media and Taxus mairei. The contents of paclitaxel and 10-deacetylpaclitaxel in T. media are higher than that in T. mairei. Then, the transcriptome profiles of T. media and T. mairei were analyzed to investigate the altered expressions. A total of 20,704 significantly differentially expressed genes (DEGs), including 9865 unigenes predominantly expressed in T. media and 10,839 unigenes predominantly expressed in T. mairei, were identified. In total, 120 jasmonic acid-related DEGs were analyzed, suggesting variations in ‘response to JA stimulus’ and ‘JA biosynthetic process’ pathways between T. media and T. mairei. Furthermore, a number of genes related to the precursor supply, taxane skeleton formation and hydroxylation, and C13-side chain assembly were also identified. The differential expression of the candidate genes involved in taxoid biosynthetic pathways may explain the variation in the taxoid contents between T. media and T. mairei.
研究领域:
植物科学
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药理学
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分子生物学
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基因组学
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DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2021
·
IF 8.198
Han Hu,Jiayi Li,Ying Tian,Chao Chen,Fenglong Li,Wu Bin Ying,Ruoyu Zhang,Jin Zhu
The very slow degradation of biodegradable polymers in the marine environment is due to the lack of dedicated degradation enzymes in open seas. As a result, introducing monomers that have a fast hydrolysis process is required to accelerate seawater degradation. Poly(butylene succinate-co-glycolate) (PBSGA) copolyesters with glycolic acid (GA) units ranging from 5 to 40% were synthesized by our newly developed polymerizing method based on oligo(glycolic acid). The results of 1H-NMR and GPC revealed that short GA segments were evenly distributed between BS segments, obtaining random copolyesters with a weight-average molecular weight over 6.24 * 104 g/mol. The copolymerized GA units hinder its crystallization capability and increase hydrophilicity of the PBSGAs, which still displayed mechanical properties comparable or even better than most biodegradable polymers. Fast degradation in seawater and enzymatic environments (Candida antarctica lipase B enzymes) is proved experimentally. The quick decomposition in seawater was originated from accelerated hydrolysis. For instance, the weight loss of PBSGA40 (compositions of GA units) exceeded 22% after 49 days. Possible degradation mechanisms were proposed based on Fukui function analysis and frontier molecular orbital calculation. Additionally, the energy barrier for hydrolysis was calculated by the density functional theory method, indicating that the hydrolysis of the polymer chain became more and more easy with the increase in GA units. At last, the addition of GA units only had a mild effect on the shelf life of the PBSGAs.
研究领域:
材料科学
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环境科学
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生物学
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DOI
高影响因子
MOLECULAR PHARMACEUTICS
·
2015
·
IF 4.384
Tingjie Yin,Qu Wu,Lei Wang,Lifang Yin,Jianping Zhou,Meirong Huo
A redox-sensitive prodrug, octreotide(Phe)-polyethene glycol-disulfide bond-paclitaxel [OCT(Phe)-PEG-ss-PTX], was successfully developed for targeted intracellular delivery of PTX. The formulation emphasizes long-circulation-time polymer–drug conjugates, combined targeting based on EPR and OCT-receptor mediated endocytosis, sharp redox response, and programmed drug release. The nontargeted redox-sensitive prodrug, mPEG-ss-PTX, and the targeted insensitive prodrug, OCT(Phe)-PEG-PTX, were also synthesized as controls. These polymer–PTX conjugates, structurally confirmed by 1H NMR, exhibited approximately 23 000-fold increase in water solubility over parent PTX and possessed drug contents ranging from 11% to 14%. The redox-sensitivity of the objective OCT(Phe)-PEG-ss-PTX prodrug was verified by in vitro PTX release profile in simulated reducing conditions, and the SSTRs-mediated endocytosis was demonstrated by flow cytometry and confocal laser scanning microscopy analyses. Consequently, compared with mPEG-PTX and OCT(Phe)-PEG-PTX, the OCT(Phe)-PEG-ss-PTX exhibited much stronger cyotoxicity and apoptosis-inducing ability against NCI-H446 tumor cells (SSTRs overexpression), whereas a comparable cytotoxicity of these prodrugs was obtained against WI-38 normal cells (no SSTRs expression). Finally, the in vivo studies on NCI-H466 tumor-bearing nude mice demonstrated that the OCT(Phe)-PEG-ss-PTX possessed superior tumor-targeting ability and antitumor activity over mPEG-PTX, OCT(Phe)-PEG-PTX and Taxol, as well as minimal collateral damage. This targeted redox-sensitive polymer–PTX prodrug system is promising in tumor therapy.
研究领域:
药学
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肿瘤学
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DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 6
·1-14
·
IF 5.3
Guo Qi,Wang Du,Ma Fei,Fang Mengxue,Zhang Liangxiao,Li Peiwu,Yu Li
Phytosterols (PSs), a class of naturally occurring bioactive lipid compounds, have been found to possess a significant cholesterol-lowering effect. In developing countries, the consumption of rapeseed oil is the primary pathway of PS intake for the general population. However, developing low-cost, real-time, and high-throughput screening techniques for PSs remains a challenge. Here, a Cu-based nanocomposite CuOx@C was synthesized via a simple method of the calcination of HKUST-1 and systematically characterized by scanning electron microscopy, transmission electron microscopy, X-ray diffraction, and X-ray photoelectron spectroscopy. The CuOx@C demonstrated excellent peroxidase-like (POD-like) activity, functioning as a peroxidase mimic to facilitate the catalysis of 3,3′,5,5′-tetramethylbenzidine (TMB) into its oxidized form (oxTMB), thereby initiating a discernible color response. On the basis of this discovery, a CuOx@C-based colorimetric method for detecting total sterols in rapeseed was successfully constructed via cascade reactions. After optimizing the conditions, the high-throughput screening of total sterols in rapeseed could be completed in only 21 min, which significantly facilitated the sensing of PSs. A linear range of 0.6–6 mg/g was achieved for the detection of total sterols in rapeseed samples, thereby satisfying the requirements for detection. In addition, due to the high stability of CuOx@C and the specificity of cholesterol oxidase, the developed method had excellent stability and selectivity toward PSs, indicating that this work has huge prospects for commercial application. This innovative work overcomes the limitation of the instrumental method and provides a portable and reliable tool for total sterols detection. It can also facilitate the development of oilseeds with a high content of PSs. Graphical abstract
研究领域:
生物化学
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食品科学
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分析化学
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DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Hao Dong,Bo Wang,Xiandong Hao,Jinyu Wang,Zhiyong Xu,Wenbo Zhao
Seeking top-performing absorbents with excellent structural stability and renewability to realize efficient removal of H 2 S from natural gas is of great importance. Here, the H 2 S absorption thermodynamic and kinetic properties by a non-aqueous liquid binary blend of monoethanolamine (MEA) and ethylene glycol (EG) was systematically studied. The addition of solvent EG not only improves the thermal stability but also reduces the viscosity of the system especially after H 2 S absorption. The absorption mechanism was revealed by the combination of experimental characterization and Density Functional Theory (DFT) calculations, which show that the absorption process is a proton transfer reaction. In addition, a quasi-primary kinetic model was used to describe the absorption kinetic behavior, with rate constants increasing with temperature and pressure. Reaction equilibrium thermodynamic model (RETM) fitting thermodynamic results showed that the enthalpy (ΔH) and entropy (ΔS) of the interaction of the absorbent with H 2 S was −40.72 kJ/mol and −114.71 J/mol/K, respectively. Most importantly, the optimum absorption temperature was calculated to be 287.80 K and the optimum desorption temperature was 386.62 K. Moreover, the desulphurization rate was verified to increase with decreasing temperature and increasing H 2 S partial pressure. Five cycles of absorption-desorption experiments were conducted at 313.15 K for absorption and 373.15 K for desorption in order to verify the good reuse properties of the absorbent. Considering the excellent thermal stability, low viscosity after H 2 S absorption, acceptable absorption capacity as well as good reversibility, it is believed that the MEA/EG blend has a significant potential in the field of desulfurization.
研究领域:
化学工程
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环境科学
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产品关联
DOI
高影响因子
ChemistryOpen
·
2021
·Vol. 10
·期 5
·560-566
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IF 2.911
Yingshuang Hui,Yulu Zhan,Wenrong Hou,Lou Gao,Yahong Zhang,Yi Tang
Graphical The product control of C6 aldose toward C6, C4 and C2 alditols have been achieved, which have depended on the well-matched between retro-aldol condensation and hydrogenation process driving by temperature, H 2 pressure and injection modes. Alcohols have a wide range of applicability, and their functions vary with the carbon numbers. C6 and C4 alditols are alternative of sweetener, as well as significant pharmaceutical and chemical intermediates, which are mainly obtained through the fermentation of microorganism currently. Similarly, as a bulk chemical, C2 alditol plays a decisive role in chemical synthesis. However, among them, few works have been focused on the chemical production of C4 alditol yet due to its difficult accumulation. In this paper, under a static and semi-flowing procedure, we have achieved the product control during the conversion of C6 aldose toward C6 alditol, C4 alditol and C2 alditol, respectively. About C4 alditol yield of 20 % and C4 plus C6 alditols yield of 60 % are acquired in the one-pot conversion via a cascade retro-aldol condensation and hydrogenation process. Furthermore, in the semi-flowing condition, the yield of ethylene glycol is up to 73 % thanks to its low instantaneous concentration.
研究领域:
生物化学
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有机化学
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产品关联
DOI
PubMed
高影响因子
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