JOURNAL OF INORGANIC BIOCHEMISTRY
·
2025
·
IF 3.2
Hao Wang,Guozhu Ren,Yue Xu,Ruiping Deng,Rui Wang,Liang Zhou
In this work, novel erbium complex with anticancer activity against radiation resistant lung adenocarcinoma cells was obtained and demonstrated. Firstly, stronger inhibitory effect of Er 3+ on non-small cell lung cancer (NSCLC) cells and NSCLC- radiation resistant (RR) cells was experimentally confirmed. Then, by selecting highly biocompatible porphyrins as ligands, a novel erbium complex tetraphenylporphyrin erbium acetylacetonate (Er(acac)TPP) was synthesized and purified. Compared with Cisplatin, notably, Er(acac)TPP exhibits relatively higher inhibitory efficiency on NSCLC-RR cells. Moreover, the toxicities of Er(acac)TPP to normal cells are much lower than that of cancer cells. Subsequently, cell expansion, increased apoptosis, a decline in mitochondrial membrane potential (MMP), an accumulation of intracellular reactive oxygen species (ROS), increased Caspase-9 protein level and G2/M arrest were seen. These data all pointed to Er(acac)TPP as a possible candidate for more research and development as a chemotherapeutic drug.
研究领域:
肿瘤学
·
药理学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Communications
·
2024
·
IF 3.7
Junshan Hu,Bin Duan,Daobin Zhu,Keyu Guo,Yuxiang Wu,Yongqiang Li,Wei Jin,Fengyi Wang,Changchun Ding
This study explored the multi-mode upconversion luminescence in YbVO 4 : Er 3+ under a 980 nm laser. The optimal doping concentration of Er 3+ ions in YbVO 4 : Er 3+ is 0.02. The phosphor exhibits green (527 nm, 2 H 11/2 → 4 I 15/2 and 553 nm, 4 S 3/2 → 4 I 15/2 ), red (654 nm, 4 F 9/2 → 4 I 15/2 ) and near-infrared emissions (803 nm, 4 I 9/2 → 4 I 15/2 ). A multi-mode temperature sensor of YbVO 4 : Er 3+ was developed, featuring three temperature sensing modes based on the luminescent intensity ratio (LIR) of 2 H 11/2 / 4 S 3/2 thermally coupled level, as well as the LIR of 2 H 11/2 / 4 F 9/2 and 4 S 3/2 / 4 I 9/2 non-thermally coupled levels. Corresponding maximum relative sensitivities were determined to be 1.21 % K −1 at 298 K, 0.93 % K −1 at 298 K, and 0.33 % K −1 at 473 K, respectively. The phosphor demonstrates notable temperature sensitivity, highlighting its potential in optical temperature sensing. This study introduces an innovative platform for crafting multi-mode self-reference optical temperature sensors, presenting substantial advancements in the field.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
Laser & Photonics Reviews
·
2024
·Vol. 19
·期 5
·2401522
·
IF 9.8
Huhui Fu,Wenfeng Xie,Yuanqi Qian,Xiao Li,Yaning Zhang,Jingbing Lu,Qi Xiong,Anhua Wu,Liangbi Su,M. Liu
Lanthanide (Ln 3+ )-doped upconversion nanocrystals (NCs) have attracted great attention due to their outstanding luminescent performance and wide applications in various fields. However, the preparation of most Ln 3+ -doped NCs requires rigorous conditions such as high reaction temperature, long reaction time, strict anhydrous and oxygen-free environment, and tedious post-treatment process. Herein, sub-100 nm Yb 3+ /Er 3+ codoped K 3 ZrF 7 octahedral NCs are prepared by an extremely simple coprecipitation method (10 s only at room temperature). The resulting NCs show excellent upconversion luminescence (UCL), significantly superior to both their conventional high-temperature-synthesized counterparts and the room-temperature-synthesized NaBiF 4 :Yb/Er controls. More importantly, abnormal thermally enhanced UCL over a temperature range from room temperature to 473 K is found in these K 3 ZrF 7 :Yb/Er NCs, making them promising candidates for ratiometric thermometry applications. By employing the luminescence intensity ratio between two non-thermally coupled energy levels of Er 3+ , namely 4 F 9/2 and 2 H 11/2 , these NCs display an extraordinarily high absolute sensitivity of 443.2% K −1 and a comparatively large relative sensitivity of 1.55% K −1 at room temperature. These results reveal that K 3 ZrF 7 :Yb/Er NCs can not only be facilely prepared via an ultrafast room-temperature synthesis, but also hold great potential in various areas such as optical temperature sensing and biological applications.
研究领域:
材料科学
·
光学
·
生物医学工程
✓ 已验证
DOI
高影响因子
RSC Advances
·
2015
·Vol. 6
·期 4
·3224-3230
·
IF 3.84
Yang Zheng,Changming Chen,Yunlong Gu,Jihou Wang,Shouzhuo Yang,Xu Fei,Xibin Wang,Yunji Yi,Xiaoqiang Sun,Fei Wang,Daming Zhang
In this study, a metal-cladding directly defined active waveguide technique is proposed. Optical waveguide amplifiers and thermo-optic (TO) waveguide switches based on erbium-containing polymer are designed and fabricated using this technique. The Er organic complexes containing polymeric reactivity groups are synthesized and investigated by free radical copolymerization. Optical characteristics and thermal stabilities of the active polymer are analyzed. Relative optical gain of the amplifier at 1530 nm is obtained as 3.6 dB. The rise and fall response time of the TO switch applied by 300 Hz square-wave voltage is measured as 511.7 μs and 341.5 μs, respectively. The power-time product is 12.5 mW ms and the extinction ratio is about 20 dB. The technique is very suitable for realizing large-scale optoelectronic integrated circuits.
研究领域:
光学
·
材料科学
✓ 已验证
DOI
高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
·
2025
·
IF 5.4
Zuodong Liu,Tingting Xiong,Chengwei Zhang,Qiyue Pan,Guo Zhang,Rui Liu,Yongsheng Yu,Peng Liu,Qiangshan Jing
A series of SrF 2 phosphors co-doped with Er 3+ and Y 3+ possessing regular polygon shapes were fabricated after calcination as-synthesized particles at 600 °C for 2 h. the crystal structure and morphology of the Er, Y:SrF 2 phosphors were identified. By incorporating the non-active Y 3+ ions as buffers into Er:SrF 2 phosphors, intense green up-conversion luminescence with modulating emission colors from reddish-yellow towards the greenish area is achieved. The two-photon up-conversion mechanism was also identified by the quadratic dependence between the luminescence intensities and 808 nm excitation source powers. The up-conversion luminescence characteristics indicate that Y 3+ buffers significantly enhance the 2 H 11/2 / 4 S 3/2 → 4 I 15/2 transitions, leading to an approximately five-fold increase in the luminescence intensities ratio R(g/r) of the green to red emissions in Er:SrF 2 phosphors.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2014
·
IF 2.726
Chuanying Wang,Xianhua Cheng
Using a facile hydrothermal method , hexagonal β-NaYF 4 :Yb 3+ 20 mol%, Er 3+ 1 mol% crystals with predictable size and morphology were synthesized and the upconversion (UC) luminescence properties were investigated. X-ray diffraction (XRD), scanning electron microscopy (SEM) and photoluminescence (PL) spectra were used to characterize the samples. The results indicated that the size and morphology of the crystals can be precisely controlled by tuning the pH values of the initial reaction solution and the molar ratio of NaNO 3 to RE 3+ (RE = Y + Yb + Er), and the mechanism was proposed. The UC luminescence properties of β-NaYF 4 :Yb 3+ /Er 3+ crystals were found to strongly depend on the crystal morphologies and sizes. The peak area ratio of green to red (R/G) increased from 0.29 to 1.03 with pH values increasing from 3 to 10, and increased from 1.03 to 1.26 with the increase of molar ratio of NaNO 3 to RE 3+ from 0 to 90. The emission colors were tuned from pure green to orange yellow. This study provides a facile way to synthesize β-NaYF 4 :Yb 3+ /Er 3+ crystals with predictable morphology and size, and tunable luminescence properties, which can be applicable for other rare earth fluoride compounds.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2023
·
IF 5.2
Wei Zhang,Xiaona Zhang,Yu Zhou,Ying Zhang
Mesoporous bioactive glasses have great potential for applications in the field of bone tissue repair due to their excellent biological properties, but effective information on the repair process is not available in a timely manner. Thus, real-time monitoring of mineralization and drug release processes will be beneficial to obtain the degree of healing and optimize the amount and distribution of drugs to improve targeted therapeutic effects. Here, erbium-doped mesoporous bioactive glass microspheres (Er/MBGs) were successfully synthesized by the sol-gel method, and the doping concentration of erbium was selected based on fluorescence, BET, and bioactivity tests. The results showed that 4Er/MBGs not only had the highest luminescence emission, higher specific surface area (418.8 m 2 /g) and mesopore volume (0.42 cm 3 /g) but also presented excellent bioactivity. Therefore, 4Er/MBGs were selected for in vitro real-time monitoring of mineralization and drug release. It has been shown that the luminescence intensity of 4Er/MBGs is linearly related to its mineralization degree; As the degree of mineralization increases in vitro , the intensity of the luminescence emission gradually decreases. The results of in vitro drug release monitoring experiments showed that 4Er/MBGs loaded with the anticancer drug doxorubicin (DOX) exhibited great pH responsiveness, and the loaded DOX selectively quenched the green emission of the microspheres. When the drug was released, the green emission recovered stably, and the signal value of the ratio R ( I 650 nm/ I 510 nm) of the emission intensity of the red to the green of the microspheres gradually decreased. Monitoring changes in the value of the R signal is instructive for tracking the drug release process. Meanwhile, in vitro antibacterial experiments indicated that 4Er/MBGs had a strong inhibitory effect on E. coli and S. aureus , with antibacterial rates of up to 92.5% and 90.7%, respectively. Collectively, Er/MBGs have potential applications as optically functional materials in bone tissue engineering.
研究领域:
生物材料学
·
骨组织工程
✓ 已验证
DOI
高影响因子
FERROELECTRICS
·
2024
·
IF 0.6
Zhao Hong,Xu Dan,Yu Taolin,Duan Xiaoyang,Zhou Xinyuan,Zhao Wenjie,He Jun
The effects of Li/Er and Li/Bi co-substitution on the structure, dielectric, and ferroelectric properties of BaTiO3 (BT) ceramics were investigated and analyzed. X-ray diffraction measurements show that the doped samples have a single tetragonal structure without secondary phases. Rietveld refinement results show that the Li/Er and Li/Bi ions tend to replace A-sites of BT lattices at low doping content. As the doping content increases, the Curie temperature moves to the high-temperature region due to the increased tetragonality and internal stress. Compared with the undoped ceramics, the ferroelectric properties of the doped ceramics are improved. The enhanced remnant polarization is attributed to the combined effects of large grain modulation and defect dipole arrangement.
研究领域:
材料科学
·
物理学
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2016
·
IF 2.758
J.L. Wu,B.S. Cao,F. Lin,B.J. Chen,J.S. Sun,B. Dong
A new upconversion (UC) host material YbMoO 4 with 0–100 mol% Er 3+ doping was obtained using a facile coprecipitation method. A pure tetragonal phase of YbMoO 4 was synthesized, which was dependent on the pH value of the reaction mixture and the sintering temperature . The existence of pentavalent molybdenum was confirmed in YbMoO 4 by thermal-reduction of hexavalent molybdenum. Under a 976 nm laser diode excitation, both green and red UC emissions were observed from Er 3+ :YbMoO 4 , which corresponded to the 2 H 11/2 / 4 S 3/2 → 4 I 15/2 and 4 F 9/2 → 4 I 15/2 transitions of Er 3+ with the strongest luminescence appearing at a mole ratio of Er:Yb=1:10. The two-photon absorption UC process was responsible for the green and red emissions. The temperature-dependent green UC emission of Er 3+ :YbMoO 4 was observed, which was rationalized using the thermal quenching model. The fluorescence intensity ratio (FIR) of green UC emissions was studied as a function of temperature and its high thermal sensitivity implied that the Er 3+ :YbMoO 4 material is a promising prototype for applications in optical temperature sensing.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Yi Xiong,Xingxing Gu,Zixun Liu,Xiaolei Ren,Yanke Jiang,Hanyu Xu,Lin Zhuo,Guangming Jiang
Rechargeable aqueous-zinc ion batteries (AZIB) have notable benefits in terms of high safety and low cost. Nevertheless, the challenges, such as dendrite growth, zinc anode corrosion, and hydrogen evolution reaction, impede its practical implementation. Hence, this study proposes the introduction of an economical ErCl 3 electrolyte additive to stabilize the Zn anode surface and address the aforementioned issues. The introduced Er 3+ will cover the raised zinc dendrite surface and weaken the “tip effect” on the surface of the zinc anode via the “electrostatic shielding” effect. Simultaneously, the introduced Cl – can reduce the polarization of the zinc anode. Due to the synergistic effect of Er 3+ and Cl – , the zinc anode corrosion, dendrite growth and hydrogen evolution have been efficiently inhibited. As a result, the Zn||Zn-symmetric battery using ErCl 3 additive can stably cycle for 1100 h at 1 mA cm −2 , 1 mAh cm −2 , and exhibit a high average coulomb efficiency (99.2 %). Meanwhile, Zn||MnO 2 full battery based on ErCl 3 -added electrolyte also demonstrates a high reversible capacity of 157.1 mAh/g after 500 cycles. Obviously, the capacity decay rate of the full battery is also improved, only 0.113 % per cycle. This study offers a straightforward and economically efficient method for stabilizing the zinc anode and realizing high-performance AZIBs.
研究领域:
材料科学
·
能源存储技术
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2012
·
IF 2.289
Hui Hu,Yan Bai
In this study, TeO 2 :Tm 3+ /Er 3+ /Yb 3+ nanoparticles had been successfully prepared via a hydrothermal process. All the as-prepared TeO 2 :Tm 3+ /Er 3+ /Yb 3+ nanoparticles showed the blue (476 nm), green (525 nm, 545 nm) and red (667 nm) emissions under 980 nm excitation, which were attributed to the 1 G 4 → 3 H 6 (Tm 3+ ), 2 H 11/2 , 4 S 3/2 → 4 I 15/2 (Er 3+ ) and 4 F 9/2 → 4 I 15/2 (Er 3+ ) transitions, respectively. The decay lifetime of blue, green and red emissions were 40 μs, 46 μs and 89 μs, respectively. The combination of blue, green and red emissions resulted in the white luminescence which was intense and visible to the naked eyes. The calculated CIE color coordinates of TeO 2 :Tm 3+ /Er 3+ /Yb 3+ nanoparticles fell well within the white region and changed little with the incident pump power from 1.75 W/cm 2 to 16.13 W/cm 2 , which indicated that the materials may have potential applications in the fields of three dimensional displays, back lighting, white light sources, and so on.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Inorganic and Organometallic Polymers and Materials
·
2013
·Vol. 23
·期 4
·1039-1042
·
IF 1.174
Luo Jianxin,Zhang Chunyan,Yang Fulin,Hu Hanxiang
A novel erbium-containing polymer precursor (Er(TTA) 3 (HCQ), TTA = 2-thenoyltrifluoroacetone, HCQ = 5-(2-methacryloylethyloxymethyl)-8-quinolinol), was synthesized, and characterized by elemental analysis, FT-IR, UV–vis absorption and photoluminescent spectra. The complex involves two different organic ligands: 5-(2-methacryloylethyloxymethyl)-8-quinolinol, which is derived from 8-hydroxyquinoline to serve not only as a ligand but also as a functional group for polymer precursor and 2-thenoyltrifluoroacetone, which is a critical component for allowing the complex to exhibit desirable photophysical properties. When excited at the absorption band of the ligand ( λ
ex = 410 nm), the complex shows a characteristic near-infrared emission of the Er ion. The full-width at half-maximum of this emission band is 97 nm, which enables a wide gain bandwidth for optical amplification.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）