ECS Journal of Solid State Science and Technology
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2019
·Vol. 8
·期 5
·P3075
·
IF 1.795
Peng He,Bingbing Wu,Shuai Shao,Tong Teng,Peng Wang,Xin-Ping Qu
Cobalt has been applied as liners in current Cu interconnect and even as interconnect conductors in next-generation interconnect. In this work, effects of corrosion inhibitors 1, 2, 4-triazole (TAZ) on Co chemical corrosion, galvanic corrosion between Cu and Co, and Co polishing properties in the H2O2 based acidic slurry have been systematically investigated. Results show that 5 mM TAZ yields a low static etching and removal rate with a selectivity of about 1: 1 for Co to Cu, applicable for Co barrier/ Cu CMP, while 100 mM TAZ yields a high removal rate with same selectivity, applicable for Co via and trench CMP. It demonstrates that TAZ can effectively inhibit the galvanic corrosion between Co and Cu. Additionally, the adsorption behavior of TAZ on Co surface is both physisorption and chemisorption. In case of 5 mM TAZ, self-assembly TAZ molecules absorb on native Co oxide. In case of 100 mM TAZ, more soluble Co-TAZ complexes form, which reduces the stability of the passivation layer and results in pitting corrosion.
研究领域:
材料科学
·
化学工程
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SEPARATION AND PURIFICATION TECHNOLOGY
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2023
·
IF 8.6
Kuixin Cui,Nan Duan,Shengming Jin
A novel collector 2-(4-Butoxyphenyl)acetohydroxamic acid (BAHA) was actively considered in the flotation of rhodochrosite. Flotation behaviors and BAHA adsorption concerning rhodochrosite, calcite and dolomite were systematacially investigated through microflotation tests, adsorption experiments, zeta potential measurements, FTIR and XPS analyses. Microflotation results showed that rhodochrosite performed a better floatability than calcite and dolomite at pH 8.0–10.0. Also, the adsorption amounts of BAHA collector on the rhodochrosite surface were obviously greater than those of calcite and dolomite. The results of zeta potential, FTIR and XPS analyses indicated that BAHA adsorbed onto rhodochrosite surfaces through chemisorption, electrostatic attraction and intermolecular hydrogen bonding, chemisorption and electrostatic attraction for calcite, and only chemisorption for dolomite. The interaction mechanisms between BAHA collector and mineral surfaces were responsible for the differences in the BAHA adsorption and floatability between rhodochrosite and two gangues. The flotation separation tests of three minerals confirmed that the rhodochrosite concentrate with Mn grade of 24.64% and recovery of 87.94% could be obtained. BAHA is a high selective collector and can realize the flotation separation of rhodochrosite against dolomite and calcite.
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MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
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2025
·
IF 4.6
Yixuan Bao,Yuping Zhang,Shilei Wang,Xuemei Liu,Jun Ma,Xiaoting Li,Yang Liao
The widespread use of 2,4-dichlorophenol (2, 4-DCP) in the paper manufacturing, dye synthesis, textile processing, and agriculture applications has led to its persistent accumulation in the ecosystems, posing significant risks to environmental safety and human health. This study developed a MIL-101(Fe)-derived porous carbon material for efficient degradation of 2, 4-DCP through potassium persulfate (PDS)-based advanced oxidation processes. Characterization demonstrated that the synthesized material, compared with its MIL-101(Fe) precursor, possessed enhanced specific surface area and pore size distribution, which could synergistically promote both adsorption and catalytic degradation of 2, 4-DCP. The optimized 700Fe-C/PDS system (0.3 g/L catalyst, 0.5 mM oxidant) achieved 95.99 % degradation rate for 50 mg/L 2, 4-DCP within 90 min, showing rapid degradation ability. Notably, the material maintained >94.34 % degradation efficiency for 2, 4-DCP after five times of reuse without requiring pH adjustment, highlighting exceptional stability and practical applicability. Reactive oxygen species quenching experiments and electron paramagnetic resonance (EPR) analysis elucidated that both radical and non-radical pathways contributed to the degradation process, with 1 O 2 playing a dominant role in the system. Furthermore, the catalyst demonstrated remarkable generalizability, eco-friendliness and effectively degradation for 2, 4-DCP in real municipal wastewater effluent and other organic pollutants including tetracycline, ciprofloxacin, acetamiprid, and sulfamethoxazole. This work provides an efficient, stable, and easily recyclable catalytic material, offering a new strategy for addressing diverse organic contaminants in complex water matrices.
研究领域:
环境科学
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材料科学
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化学工程
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LUMINESCENCE
·
2025
·Vol. 40
·期 6
·e70219
·
IF 3
Junxia Wang,Ying Qin,Na Li,Yu He,Gongwu Song
2, 4-dichlorophenoxyacetic acid is a widely used pesticide, necessitating the development of a low-cost, reliable, and rapid detection method. In this work, BCNO quantum dots were synthesized by a one-step microwave method. A fluorescence “turn-off-on” probe for 2, 4-dichlorophenoxyacetic acid detection was developed using MnO 2 nanosheets due to their strong oxidation and broad absorption spectrum. MnO 2 nanosheets can quench the fluorescence of BCNO quantum dots through internal filter effect. Alkaline phosphatase hydrolyzes trisodium L-ascorbate-2-phosphate to produce ascorbic acid, which decomposes MnO 2 nanosheets, restoring the fluorescence of BCNO quantum dots. With the increase of alkaline phosphatase concentration, the ascorbic acid produced gradually increased; thus, the fluorescence intensity of BCNO quantum dots increased. 2, 4-dichlorophenoxyacetic acid inhibits alkaline phosphatase activity, preventing the decomposition of MnO 2 nanosheets and hindering fluorescence recovery. The probe exhibits a linear detection range of 1.0–40.0 mg/L and a detection limit of 0.067 mg/L. Color changes corresponding to 2, 4-dichlorophenoxyacetic acid concentration were analyzed using a smartphone application, establishing a digital image colorimetry method. The results demonstrated a good linear relationship within the range of 0–50 mg/L. The method was validated with real samples, demonstrating its utility in environmental and food safety monitoring.
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ENVIRONMENTAL TECHNOLOGY
·
2022
·
IF 3.475
Dairui Xie,Hao Huang,Heng Zhang,Fang Shen,Meng Jiang,Xiaoting Li,Hongyan Shang,Jun Ma,Shilin Zhao
The amphiphilic humic acid ester ether (HAEE), as a kind of solid-phase extractant with characteristics of easy separation and hydrophilic–hydrophobic amphiphilic property, was prepared and used to extract micro or trace nitrofen, 2,4-dichlorophenol and p-nitrotrophenol (NIPs) from water and soil. Degradation of NIPs and extractant regeneration were carried out by simple photocatalysis. The adsorption equilibrium of the mono- or three mixed NIPs by HAEE in aqueous could be quickly reached within 20 min. The adsorption process was fit to quasi-second-order kinetics model and Friendlich thermodynamics model. The possible adsorption interaction was discussed. Results suggested that the adsorption of NIPs onto HAEE predominated by hydrogen bonding, hydrophobic interaction and π-π interaction. The extraction capacity of mixed NIPs (80 μg/L each component) by HAEE was up to 0.38 mg/g and tended to be multi-layer adsorption, in which p-nitrotrophenol had higher adsorption competitiveness because of lower resistance to HAEE. When HAEE-NIPs were degraded by photo-catalyst Fe0/F-TiO2 for 8 h, not only the adsorbed NIPs could be totally degraded and mineralized, but also the HAEE could be effectively regenerated. When the NIPs were continuously extracted from 40-year aging soil for three times (regenerative twice) by combined extractant (48 mL H2O + 2 mL n-hexane + 0.1 g HAEE), the total extraction efficiency of NIPs could reach to 84.66%. This research could supplement the theory and technique for harmless treatment of NIPs contaminated water and soil.
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CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Na Tian,Xike Tian,Yulun Nie,Chao Yang,Zhaoxin Zhou,Yong Li
Peroxymonosulfate (PMS) activation has drawn increasing attention in eliminating the recalcitrant organic pollutants in water. Manipulation of generated reactive oxygen species (ROS) over Ce doped Mn 2 O 3 during the PMS activation was firstly reported for the complete degradation of 2,4-dichlorophenol (2,4-DCP) in this study. Ce in-situ introduction can greatly enhance the PMS activation performance of Mn 2 O 3 . For example, 100% of 2,4-DCP degradation can be obtained at 90 min over 4 wt% Ce doped Mn 2 O 3 at pH 7 (82.1% for Mn 2 O 3 at 90 min). The reaction rate constant ( k ) was also about 3.6 times higher than that of Mn 2 O 3 (0.0668 min −1 for Ce doped Mn 2 O 3 vs. 0.0186 min −1 for Mn 2 O 3 ). Besides 1 O 2 , OH and SO 4 − were identified and involved in 2,4-DCP degradation process over Ce doped Mn 2 O 3 , while only 1 O 2 was detected over 3D Mn 2 O 3 . Moreover, the contribution of OH and SO 4 − to 2,4-DCP degradation can be regulated by adjusting the Ce doping amount. The key role of Ce substitution in the regulation of reactive oxygen species was further investigated by XPS and electrochemical experiments. The Ce dopant can lead to a higher current density and greater reductive capability due to the improved charge transfer capability, which is important to the generation of more aggressive OH and SO 4 − and complete 2,4-DCP degradation.
研究领域:
环境科学
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材料科学
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化学工程
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Food Analytical Methods
·
2016
·Vol. 10
·期 1
·111-117
·
IF 2.167
Liu Qi,Wang Li,Hu Jie,Miao Yanni,Wu Zixue,Li Jianrong
A rapid and sensitive analytical method for the determination of main organic acids in wines was developed by capillary electrophoresis (CE) with indirect UV detection. Separation parameters including the pH of electrolyte, chromophore, and its concentration were optimized. The results showed that the optimal electrolyte for the separation of organic acids consisted of 10 mmol L −1 2, 4-dihydroxybenzoic acid (DHBA) at pH 3.6 containing 0.4 mmol L −1 cetyltrimethlammonium bromide (CTAB). DHBA as chromphore was selected based on the close mobility to the analyte and relatively large molar extinction coefficient. The method showed good linearity with limits of detection (LOD), ranging from 0.5 to 7.5 mg L −1 . The relative standard deviation (RSD) of interday precisions for the peak area and the migration time were less than 7.2 and 0.8 %, respectively. The recoveries of the analyte in Chinese rice wine sample were between 90.3 and 106.9 % with RSD ranging from 1.4 to 8.9 %. The method was successfully applied to the commercial rice wine and beer samples with dilution and filtration.
研究领域:
分析化学
·
食品科学
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JOURNAL OF SOLUTION CHEMISTRY
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2023
·Vol. 52
·期 7
·762-789
·
IF 1.2
Li Min,Zhang Xiaocheng,Yu Yingmin,Liu Lanmu
The extractive distillation was used to separate ethylbenzene and m-xylene. After the solvent screening, 1,2,4-trichlorobenzene was chosen as the extractive solvent. The vapor–liquid equilibrium (VLE) of binary mixtures of m-xylene, ethylbenzene, and 1,2,4-trichlorobenzene was measured at 101.33 kPa. The measurements were taken with a modified Rose equilibrium still. The Wisniak’s test was used to assess the thermodynamic consistency of the VLE experimental results. To obtain the binary interaction parameters, the binary VLE experimental data were correlated with the NRTL, Wilson, and UNIQUAC activity coefficient models. The results showed that three models all fit the experimental values of three binary systems well, and the ternary VLE data of m-xylene + ethylbenzene + 1,2,4-trichlorobenzene were estimated using Aspen Plus V11 based on these model parameters. The experimental data agree well with the estimation values generated from three models. Finally, the effect of 1,2,4-trichlorobenzene as an extractant was analyzed, and it is proved to have a good influence on the separation of ethylbenzene from mixed xylenes by extractive distillation.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2022
·
IF 3.119
Zhengxu Li,Hao Wu,Baifeng Hu,Jin Guo,Yuxiang Liu,Han Yue,Hongkang Zhao,Qunsheng Li
The solubility of 2′,4′-dihydroxyacetophenone (2′,4′-DHAP) in 10 monosolvents (methanol, ethanol, n-propanol, isopropanol, n-butanol, isobutanol, methyl acetate, ethyl acetate, propyl acetate, and benzene) and two binary solvents (ethanol + ethyl acetate and n-propanol + ethyl acetate) was determined using a gravimetric method at 101.3 kPa from 293.15 to 333.15 K. The experimental solubility was demonstrated to increase with the increasing temperature. The solubility of 2′,4′-DHAP is the highest in pure isopropanol, and the two binary solvents present a solubilizing effect on the solute. Furthermore, six thermodynamic models were employed to fit the solid–liquid equilibrium data, and the correlation results manifested that the modified Apelblat model had minimum ARD values of less than 1%. Finally, the KAT-LSER model was employed to analyze the solvent effect at 298.15 K. The results show that the contribution of the four interaction types α, β, π*, and δH account for 15.84%, 15.30%, 18.33%, and 50.53% of the total interaction force, respectively, and the solvent–solvent interaction represented by δH is the dominant factor affecting the solubility of 2′,4′-DHAP.
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THIN SOLID FILMS
·
2019
·
IF 1.888
Jian He,Aisen Li,Yanchun Tao,Ning Chu,Zhixiang Wang,Shuping Xu,Jing Wang,Houyu Zhang,Jingsheng Yu,Weiqing Xu
A two-dimensional (2D) co-crystal composed of 1, 3, 5-trifluoro-2, 4, 6-triiodobenzene and 4, 4′-trimethylenedipyridine via halogen bonding (I···N) was obtained on highly-oriented pyrolytic graphite , and was characterized by scanning tunnelling microscope supplemented by the density functional theory calculation. Its special structure at the interface was further compared with its three-dimensional (3D) co-crystal structure. No orderly structures were observed when Au (111) was applied. The 2D co-crystal grown on the interface is significantly different from the 3D co-crystal. This study is of vital significance in understanding the growth mechanisms of 2D functional co-crystals.
研究领域:
材料科学
·
化学
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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
·
2021
·
IF 6.514
Xing-Rong Wang,Shuai Wang,Wen-Bo Li,Kai-Yan Xu,Xue-Peng Qiao,Xue-Li Jing,Zi-Xiao Wang,Chang-jiang Yang,Shi-Wu Chen
Vascular endothelial growth factor-2 (VEGFR-2) plays a pivotal role in tumor angiogenesis . Herein, a library of novel 2-(4-(1 H -indazol-6-yl)-1 H -pyrazol -1-yl)acetamide derivatives were designed and synthesized as VEGFR-2 inhibitors based on scaffold hopping strategy. These compounds exhibited the excellent inhibitory in both VEGFR-2 and tumor cells proliferation . Especially, compound W13 possessed potent VEGFR-2 inhibition with IC 50 = 1.6 nM and anti-proliferation against HGC-27 tumor cells with IC 50 = 0.36 ± 0.11 μM, as well as less toxicity against normal GES-1 cells with IC 50 = 187.46 ± 10.13 μM. Moreover, W13 obviously inhibited colony formation, migration and invasion of HGC-27 cells by adjusting the expression of MMP-9 and E-cadherin, and induced HGC-27 cells apoptosis by increasing ROS production and regulating the expression of apoptotic proteins. Furthermore, W13 blocked the PI3K-Akt-mTOR signaling pathway in HGC-27 cells. In addition, anti-angiogenesis of W13 was proved by inhibiting tube formation and the expression of p-VEGFR-2 in HUVEC cells. All the results demonstrated that W13 could be developing as a promising anticancer agent for gastric cancer therapy.
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MEDIATORS OF INFLAMMATION
·
2021
·
IF 4.711
Qiang Zheng,Hang Zhao,Dong Jia,Xu Han,Zhenning Liu,Min Zhao
Paraquat (PQ) can cause multiorgan failure including acute kidney injury (AKI). Our prior study showed that Toll-interacting protein (TOLLIP) protected against PQ-induced acute lung injury. However, the role of TOLLIP in PQ-induced AKI remains undefined. This study was aimed at understanding the role and mechanism of TOLLIP in AKI. Six-eight-week-old male Wistar rats were intraperitoneally injected with 25 mg/kg PQ to induce AKI for 24 h in vivo. HK-2 cells were treated with 300 μM PQ for 24 h to induce cellular injury in vitro or 300 μM PQ and 5 μM nuclear factor-κB (NF-κB) inhibitor BAY11-7082 for 24 h. Rats were infected with adenovirus carrying TOLLIP shRNA via tail vein injection and HK-2 cells with adenovirus carrying TOLLIP shRNA or TOLLIP 48 h before PQ exposure. Results showed that TOLLIP and Toll-like receptor 2/4 (TLR2/4) expressions were boosted in the kidney after PQ intoxication. The toxic effect of PQ on the kidney and HK-2 cells was exacerbated by TOLLIP knockdown, as evidenced by aggravated glomerulus and tubule injury, inflammatory infiltration, and cell apoptosis in the kidney and increased loss of cell viability and apoptotic cells in HK-2 cells. TOLLIP knockdown also enhanced PQ-induced NLR family pyrin domain-containing 3 (NLRP3) inflammasome activation in vivo and in vitro and TLR2/4-NF-κB signaling in vitro, reflected by increased contents of proinflammatory cytokines and expressions of NLRP3 inflammasome-related proteins in the kidney and HK-2 cells and expressions of TLR2, TLR4, and nuclear NF-κB p65 in HK-2 cells. However, TOLLIP overexpression inhibited PQ-induced loss of cell viability, cell apoptosis, NLRP3 inflammasome activation, and TLR2/4-NF-κB signaling in vitro. Additionally, BAY11-7082 abolished TOLLIP knockdown-induced NLRP3 inflammasome activation in vitro, indicating that TOLLIP protected against NLRP3 inflammasome activation in PQ-induced AKI through inhibiting TLR2/4-NF-κB signaling. This study highlights the importance of TOLLIP in AKI after PQ intoxication.
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