Chinese Medicine
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2026
·Vol. 21
·期 1
·20
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IF 5.7
Yang Yanan,Shao Yuwei,Tian Jun,Wang Yuezhu,Zhu Ye,Pan Siying,Wei Xiali,Jiang Linyan,Wang Xiaoke,Shu Qing
Background Electroacupuncture (EA) has demonstrated efficacy in ameliorating obesity through its marked appetite-suppressing effects. This study aims to elucidate the peripheral-central communication mechanism underlying EA's appetite inhibition mediated by the “vagal afferent fiber–nucleus tractus solitarius (NTS)–hypothalamic arcuate nucleus (ARC)” neural circuit. Methods High-fat diet-induced obese rats received EA or transcutaneous auricular vagus nerve stimulation (taVNS) for 8 weeks. Furthermore, we employed chemogenetic approaches to activate NTS glucagon-like peptide-1 (GLP-1) neurons (NTS GLP−1 ) and utilized capsaicin for gastric vagal deafferentation (GVND). Outcomes included metabolic profiles, vagal electrophysiology, expression of NTS GLP−1 and hypothalamic appetite-regulating neuropeptides, and neuronal activation markers. Results We observed reduced expression of GLP-1 in the NTS of obese rats. Chemogenetic activation of NTS GLP−1 significantly suppressed appetite, mitigated obesity, and modulated hypothalamic pro-opiomelanocortin (POMC) and neuropeptide Y (NPY). Following EA intervention in obese rats, concurrent activation of NTS GLP−1 and vagal afferent fibers was observed. Similar to chemogenetic NTS GLP−1 activation, EA upregulated the anorexigenic peptide POMC while downregulating the orexigenic peptide NPY in the ARC. Chemogenetic inhibition of GLP-1 neurons during EA application partially inhibited its anti-obesity and anorectic effects. Further investigations revealed that both EA and taVNS effectively reduced food intake and alleviated obesity. While both interventions activated vagal pathways and NTS GLP−1 , EA induced a significantly stronger activation of vagal afferent fibers compared to taVNS. Critically, GVND prior to EA application attenuated its anti-obesity effects. Conclusion The therapeutic benefits of EA in appetite suppression and obesity mitigation are mediated by selective regulation of the “vagal–GLP-1–ARC” neural circuit. Graphical s
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PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2026
·
IF 6.7
Zhihong Wang,Tianyu Zhang,Dong Han,Wenkang Yi,Ruina Ma,An Du,Yongzhe Fan,Xue Zhao,Xiaoming Cao
Amorphous SiO 2 /MgO/MgSiO 3 coatings formed on AZ91D via MAO in TEOS electrolyte. • Due to its dense layer, this coating exhibits high corrosion resistance at 50 Hz. • Amorphous SiO 2 /MgO/MgSiO 3 coatings show optimal thermal control at 500 Hz. • Explains the growth mechanism of the coating. In this paper, AZ91D magnesium alloy is used as the substrate, and thermal control and corrosion resistant composite coatings are prepared by micro-arc oxidation technology in tetraethyl orthosilicate hydrolysis electrolyte at different pulse frequencies (50 Hz, 500 Hz, 1000 Hz, 2000 Hz). The effects of pulse frequency on the microstructure, corrosion resistance, and thermal control performance of the coatings are systematically studied. The results show that the coatings are mainly composed of SiO 2 , MgO, and MgSiO 3 . As the frequency decreases, the content of amorphous SiO 2 in the coating increases, and both the thickness and roughness increase significantly. Electrochemical tests show that the coating prepared at 50 Hz exhibits the optimal corrosion resistance, with a corrosion current density as low as 1.017 × 10⁻⁸ A/cm², and its dense inner layer resistance increases by 2.8 orders of magnitude compared with that of the coating prepared at 2000 Hz. In terms of thermal control performance, the coating at 500 Hz shows the best comprehensive thermal control performance, with an emissivity of 0.89 and an absorptivity as low as 0.30, which is attributed to the moderate thickness (about 143 μm) and roughness, the dense structure, and the intrinsically low absorptivity and high emissivity characteristics of amorphous SiO 2 . In this study, SiO 2 /MgO/MgSiO 3 composite coatings are prepared on the Mg substrate surface, which provides a new idea for the preparation of multifunctional coatings.
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高影响因子
CERAMICS INTERNATIONAL
·
2026
·
IF 6
Yuguan Wu,Chunsheng Ma,Guangrun Zang,Hao Liu,Wenbin Xue,Jingguo Fu
To enhance the reliability and durability of the aluminum alloy pistons for automobile engines, the micro-arc oxidation (MAO) and silica lubricating oil additive were introduced to construct a durable anti-friction and wear-resistant route. The Raman spectrum and time-of-flight secondary ion mass spectrometry (TOF-SIMS) were carried out to analyze the effect of silica concentration on the performance of MAO coatings. Results showed a wearable MAO coating with elevated adsorption performance (Si-O, and Si-OH bonds, η-Al 2 O 3 , γ-Al 2 O 3 ) and a complex network structure (Si-O-Al) were prepared on the surface of ZL109. Friction and wear tests illustrated the construction of a friction- and wear-resistant mechanism from a dense layer of MAO coatings, a possible silica third-body coating, and carbonaceous films generated at the friction-pair interface. The friction coefficient was reduced by 54 percent, and the wear loss on the MAO coating was reduced by 90 percent. Surface engineering strategies have shown promising applications in automobile engines.
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SENSORS AND ACTUATORS A-PHYSICAL
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2024
·
IF 4.1
Junyao Wang,Lixiang Li,Huan Liu,Qi Hou,Guanjun Zhu,Hongxu Pan,Yahao Liu,Yansong Chen,Guangzhe Gao,Taipeng Wang,Yaqun Li,Dingyi Ren
Flexible sensors are an important part of flexible electronic devices, and its application often relies on external power sources . However, traditional commercial batteries require repeated charging, lack of flexibility and potential leakage of electrolyte contamination, which seriously hinder the wearable smart electronic devices' develop of comfortable and portable integration. To overcome this key challenge. This paper combines energy harvesting technology, distributed energy storage devices and flexible electronics. This proposes a modular layout of friction nanogenerator (TENG), miniature solid-state supercapacitor (MSSC) and strain sensor. Three of modular components are constructed on a thermoplastic polyamide film. The basic conductive network is prepared through screen printing technique and graphene multiwall carbon nanotubes (G-MWCNTs) conductive inks . The TENG module is used to collect low-frequency and high-entropy mechanical energy from the surrounding environment for conversion into AC electrical energy. The MSSC module is used to store the electrical energy generated by the TENG and to continuously power the back-end flexible electronics. The strain sensor module has an asymmetric interlaced double-arc snake rib conductive structure inspired by the spotted snake. It enables multi-dimensional strain detection and ultra-sensitive sensing performance. Finally, as a concept proof, the prepared TENG, MSSC and strain sensors are composed to form a self-powered multimode distributed flexible sensing device. It can be used for human health monitoring in the areas of knuckle, elbow, hip and heel nodes.
研究领域:
材料科学
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生物医学工程
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能源技术
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
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IF 5.4
Zhiyuan Guo,Jingfu Song,Guoqing Wang,Gai Zhao
The 2A12 aluminum alloy is widely utilized in aerospace, automotive, and marine engineering due to its excellent strength-to-weight ratio and good machinability. However, its wear and corrosion resistance under harsh conditions are insufficient and require improvement. This study combined micro-arc oxidation (MAO) with paraffin sealing to enhance the corrosion resistance and tribological properties of 2A12 Aluminum Alloy. The results indicate that the MAO process significantly increases hardness and tribological properties, but the porosity into the oxidation layer may accelerate corrosion in corrosion environments. Paraffin sealing effectively fills these pores, reducing the penetration of corrosive agents and significantly improving corrosion resistance. Additionally, friction tests show that the hybrid coating after paraffin sealing exhibit a lower friction coefficient and wear rates. Molecular dynamics simulations (MD) further reveal the distribution of paraffin within the pores and its effect on wear and corrosion resistance. This study demonstrates that MAO combined with paraffin sealing is an effective approach to enhancing the corrosion and tribological properties of 2A12 aluminum alloy, providing new insights for its applications.
研究领域:
材料科学
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表面工程
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高影响因子
Journal of Nanomaterials
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2016
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IF 1.758
Minpeng Liang,Jianxin Zou,Xiaoqin Zeng,Wenjiang Ding
In the present work, a method combining arc plasma evaporation of a metal followed by oxidation in air was developed to produce nanosized metal oxide based composites in large scale. As an example, Fe2O3 based nanocomposites were prepared through such a method. With increasing the oxidation temperature, α-Fe2O3 content in the composites increases, while γ-Fe2O3 and residual α-Fe contents decrease. As anode materials for lithium batteries, the electrochemical properties of nanosized Fe2O3 composites were tested. It was found that the anode materials changed to tiny crystallites and then followed by grain growth during the galvanostatic charge/discharge cycles. A capacity rising was observed for the composites obtained at 400°C and 450°C, which was more prominent with increasing the oxidation temperature. Among these composites, the one obtained at 450°C showed the best performance: a specific capacity of 507.6 mAh/g remained after 150 cycles at a current density of 200 mA/g, much higher than that of the commercial nano-Fe2O3 powder (~180 mAh/g after 30 cycles).
研究领域:
材料科学
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能源存储
·
纳米技术
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高影响因子
FERROELECTRICS
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2017
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IF 0.551
Shaolei Xie,Shuangbin Li,Jiang Xiao,Ying Yao,Yongzhong Jia
PbTiO3 and CaTiO3 ceramics are prepared at temperatures above 2000°C by a direct current arc discharge technique under an argon atmosphere, and the microstructure, components and morphology of each material are investigated. Both samples show the formation of a perovskite structure. Moreover, a tetragonal phase is found in the PbTiO3 ceramic material, and a cubical phase is formed in the CaTiO3 ceramic material. In this work, PbTiO3 and CaTiO3 ceramics were rapidly prepared using a simple DC arc discharge technique; we found this technique of ceramic material synthesis was much faster and better than conventional methods. The whole reaction process only takes 30 seconds because of ultrafast kinetics of crystallization.
研究领域:
材料科学
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陶瓷工程
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2023
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IF 8.6
Chen Li,Wei Liu,Fen Jiao,Congren Yang,Gonghao Li,Shiyang Liu,Wenqing Qin
Electric arc furnace dust (EAFD), an important secondary resource, is categorized as hazardous solid waste which contains multiple heavy metals such as zinc, lead and chromium. Smelting-Reduction is considered as an effective method to recover metal elements from EAFD. To efficiently separate the zinc, lead, iron and slag from EAFD, a novel and clean process developed to enhance reduction and lower smelting temperature through sodium carbonate was proposed herein. Thermodynamic analysis and laboratory experiments were carried out to determine the feasibility and reliability of this new process. The optimal conditions were determined as temperature of 1450 °C, sodium carbonate dosage of 4%, C/O of 0.8, holding time of 30 min and basicity of 0.8, and the corresponding volatilization of Zn and Pb could be 99.78% and 89.47% respectively; besides, the reduction of iron could reach 98.98%. Simultaneously, the recovery of iron reached 98.62% and the grade of iron amounted to 93.8%. The melting reduction process of zinc, lead and iron could be divided into three stages according to both the experimental results and the thermodynamic analysis. The short process which is characteristic of high efficiency and low energy consumption, aims to provide a clean and sustainable approach to utilize EAFD.
研究领域:
冶金工程
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环境科学
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材料科学
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高影响因子
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
·
2014
·Vol. 28
·期 15
·1764-1768
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IF 2.642
Zhong-yao Zhang,Cuiping Li,Chuan-fan Ding,Fuxing Xu,Baoqiang Li,Qibin Huang,Hengxin Xia
RATIONALE The pivotal challenge associated with miniature mass analyzers is their proper design and construction without sacrificing performance. In order to analyze and improve the performance of a miniature linear ion trap with odd and even multipole fields, we designed a novel asymmetrical arc-shaped electrode ion trap (AAEIT), and tested the properties of AAEITs with different dimensions. METHODS A series of asymmetrical ion traps using arc-shaped electrodes were designed to optimize the properties (resolutions and intensity) of the coupling effects between odd and even multipole fields. Using arginine and reserpine, we evaluated the performance of mass resolution, ion intensity ratio and deduced the collision-induced dissociation (CID) efficiency using a self-constructed electrospray ionization mass spectrometry (ESI-MS) platform. RESULTS An AAEIT with field radius dimensions of 5 mm × 5.75 mm exhibits a good performance: its maximum resolution of 833 (FWHM) at m/z 175 was achieved for the side of small electrode. With this AAEIT, a tandem mass (MS/MS) capability with 91.0% CID efficiency was obtained with reserpine ( m/z 609). CONCLUSIONS The results indicated that the AAEIT, comprising both odd and even multipole fields, could act as a qualified linear ion trap mass analyzer with compact structure, high resolution, and high tandem mass analysis efficiency. It has a great potential in miniature mass spectrometry. Copyright © 2014 John Wiley & Sons, Ltd.
研究领域:
分析化学
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质谱技术
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高影响因子
Journal of Central South University
·
2021
·Vol. 28
·期 9
·2701-2710
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IF 1.716
Zhang Du-chao,Liu Ruo-lin,Wang Hao,Liu Wei-feng,Yang Tian-zu,Chen Lin
To recover zinc from electric arc furnace (EAF) dust, a process of primary normal pressure leaching and secondary alkaline pressure leaching is proposed. First, under the alkaline pressure leaching system, the experiment of pure zinc ferrite being reduced by iron powder was carried out. Under the optimal reduction conditions (i.e., temperature of 260 °C, NaOH concentration of 6 mol/L, liquid-to-solid ratio of 50 mL/g, and a 5-fold excess of iron powder), 89% of zinc was extracted. The iron in the reduced residue exists as a magnetite phase. Subsequently, the normal pressure leaching experiment was carried out with EAF dust as raw material, and 66% zinc was leached. The main phase of zinc in normal leaching residue was determined to be zinc ferrite. Then, the normal leaching residue was reduced by iron powder under the alkaline pressure leaching system, and 66.5% of zinc was extracted. After the two-stage leaching process, the leaching rate of zinc in EAF dust can achieve 88.7%. The alkaline pressure leaching solution can be returned as the normal pressure leaching solution, and the magnetite in the alkaline pressure leaching residue can be recovered by magnetic separation.
研究领域:
冶金工程
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环境工程
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高影响因子
JOURNAL OF THERMAL SPRAY TECHNOLOGY
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2022
·Vol. 31
·期 6
·1906-1917
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IF 2.839
Li Ning,Tian Ye,Yang Rui,Zhang Haijun,Li Hua,Chen Xiuyong
This study aimed to prepare a superhydrophobic coating by applying low surface energy (LSE) materials to a rough surface, intending to achieve a corrosion-resistant coating. Polyurethane (PU) and fluorinated polyurethane (FPU) were synthesized via designed routes as LSE materials. Arc-sprayed aluminum (Al) coatings and 316L stainless steel substrates (316L SS) were used as the rough and smooth surfaces, respectively. The synthesized PU/FPU coatings were formed on the Al coatings and 316L SS, and their hydrophobicity and corrosion resistance were evaluated. The water contact angle test showed that the content of the fluorine and the concentration of the PU/FPU could affect the hydrophobicity of the surface. In addition, superhydrophobicity was achieved via applying FPU to a rough Al coating surface (Al-FPU coating). Furthermore, the Al-FPU coating also exhibited better corrosion resistance than that of the PU and the pure Al coatings according to Tafel polarization curves and electrochemical impedance spectra in artificial seawater. The results suggested that surface energy and surface roughness were correlated with hydrophobicity, and the modification via fluorinating can be an effective method to achieve superhydrophobicity and corrosion resistance for thermal-sprayed coatings.
研究领域:
材料科学
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表面工程
·
腐蚀科学
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高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Huijing Li,Long Li,Hao Zhang,Junjie Wei,Zhenyu Xu,Tao Chen
To make soft robotics intelligent, dazzling artificial skin and actuators have been created. However, compared to rigid commercial robots, the sophisticated demands of raw materials become a key challenge for autonomous soft actuators to realize manufacturing repeatability and reproducibility. Inspired by the stem cell, which has the potential to differentiate into multifunctional cells with the same original compositions, a potential multifunctional gel is presented. With well-designed polymer chains, the gel has a salt-induced regulating module, conductivity, and other bionic properties. Making use of this advantage, the gel acts as a double-duty electrode for both the actuator and sensor. An artificial reflex arc is therefore formed by their tight integration via an e-brain: a computing unit that specifically responds to organism intervention. This efficient strategy to obtain diverse components with minimal raw materials is promising for effortlessly fabricating fully soft robotics.
研究领域:
材料科学
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生物工程
·
机器人学
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PubMed
高影响因子
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