INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2020
·
IF 5.162
Zhenguang Liu,Haiyu Ni,Lin Yu,Shuwen Xu,Ruonan Bo,Tianxin Qiu,Pengfei Gu,TianYu Zhu,Jin He,Adelijiang Wusiman,Shaowu Zhu,Jiaguo Liu,Yuanliang Hu,Deyun Wang
Recently, the cubosomes have been widely studied as drug carriers. It has been described that cubosomes could further stimulate the immune response after carrying the immune enhancer. Polygonatum sibiricum polysaccharide (PSP), one of the most important biologically active ingredients of Polygonatum sibiricum , has been reported as an immunostimulant to improve immune responses. This study was aimed to observe the immunomodulation effects of ovalbumin (OVA) absorbed cetyltrimethylammonium bromide-modified Polygonatum sibiricum polysaccharide cubosomes (CTAB-modified PSP-Cubs/OVA). Firstly, the antigen uptake of CTAB-modified PSP-Cubs/OVA by macrophages was determined in vitro. After that, mice were immunized with CTAB-modified PSP-Cubs/OVA. The activation of dendritic cells in lymph nodes, activation of lymphocyte, ratios of CD4 + to CD8 + , the concentrations of OVA-specific IgG in serum and the cytokines concentrations were analyzed. As the results showed, CTAB-modified PSP-Cubs/OVA could promote the production of OVA-specific IgG in serum. The ratio of CD4 + to CD8 + in CTAB-modified PSP-Cubs/OVA group was significantly increased compared with other groups. CTAB-modified PSP-Cubs/OVA could significantly activate dendritic cells and promote lymphocyte proliferation. The results indicated that CTAB-modified PSP-Cubs/OVA could promote the secretion of related cytokines and the proliferation of lymphocytes, stimulate the cellular immune response and increase the level of humoral immunity. Above all, CTAB-modified PSP-Cubs had good adjuvant activity.
研究领域:
免疫学
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药剂学
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生物技术
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DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2024
·Vol. 25
·期 24
·13541
·
IF 4.9
Xu Geng,Yan Wei,Yuanxin Li,Siqi Zhao,Zhengqiang Li,Heng Li,Chen Li
Microbial attack, particularly fungal degradation of cellulose, is a leading cause of paper damage. To address fungal spores and the rising concern of microbial drug resistance, a nano-Germanium dioxide (GeO2)/cetyltrimethylammonium bromide (CTAB) complex (nano-GeO2/CTAB complex) with potent antibacterial properties was synthesized. Its inhibitory effects were evaluated against bacteria, including Gram-positiveStaphylococcus aureusand Gram-negativeEscherichia coli, as well as fungi isolated from paper (Fusariumspp.,Aspergillusspp., andPenicillium citrinum). The nano-GeO2/CTAB complex exhibited significant (p< 0.05) inhibitory effects againstS. aureusandE. coli. Moreover, a 60 min treatment with 1 mg/mL of the complex significantly inhibited the growth of all tested fungi and reduced their biomass after five days of culture, while 4 mg/mL completely deactivated spores. Filter paper pre-treated with the nano-GeO2/CTAB complex showed complete resistance to microbial attack, exhibiting no fungal growth and a clear inhibition zone devoid of bacterial growth. In contrast, untreated controls displayed fungal coverage exceeding 95% within five days. These findings highlight the nano-GeO2/CTAB complex as a promising antimicrobial agent for protecting paper materials from microbial degradation.
研究领域:
材料科学
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微生物学
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文物保护科学
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DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Junyan Cui,Menghui Wan,Zhihua Wang,Yanbao Zhao,Lei Sun
Air particulate pollution from increasing industrialization poses an enormous threat to public health. It is therefore of particular importance to develop air filters with excellent filtration properties and antimicrobial properties. Here we design a novel air filter for outdoor personal protection. The air filter’s composite nanofibrous materials are prepared by electrospinning method using polyacrylonitrile (PAN) as the base polymer, silica dioxide (SiO 2 ) as the electret r and cetyltrimethylammonium bromide (CTAB) as the antimicrobial agent. Fourier-infrared spectroscopy, surface potential, and X-ray photoelectron spectroscopy characterization reveal the successful incorporation of SiO 2 and CTAB into PAN . The air filtration test shows that the composite nanofibrous membrane has outstanding PM 0.3 filtration efficiency (98.5%) and lower pressure drop (76 Pa) at 32 L/min flow rate. Moreover, the durability tests show that the composite nanofibrous membranes have a long lifetime in terms of filtration performance. The filtration efficiency is reduced by only 2% after 48 h. In addition, the antimicrobial properties were tested by implementing both E. coli and S. aureus with up to a 99% bacteriostasis rate. Thus, this work improves the application potential of high-performance air filters for the removal of particulate pollution and may provide useful insights into the design of next-generation air filters suitable for applications in high antibacterial applications.
研究领域:
材料科学
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环境科学
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纳米技术
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生物医学工程
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DOI
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
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2019
·Vol. 319
·期 3
·1251-1259
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IF 1.186
Hui Junjie,Wang Youqun,Liu Yuhui,Cao Xiaohong,Zhang Zhibin,Dai Ying,Liu Yunhai
With the aim of gathering uranium from ground aquatic environment in which uranium mainly occurs in negative species, the montmorillonite (MT) intercalated with cetyltrimethylammonium bromide (CTAB) was fabricated. X-ray diffraction and Fourier transform infrared spectroscopy were utilized to prove the entrance of CTAB into MT. Adsorption of uranium onto CTAB-MT was studied with respect to effect of pH, carbonate, calcium, humic acid, contact time, initial uranium concentration, and temperature. The adsorption negatively depended on pH, carbonate and calcium ion and humic acid concentrations. CTAB-MT had a higher uranium adsorption ability. The maximum monolayer uranium adsorption amount of CTAB-MT calculated by well fitted Langmuir model was determined as 213.31 mg g −1 , preceding 82.17 mg g −1 of MT. The adsorption kinetics was well fitted by pseudo-second-order model. The uptake mechanism involved ion exchange and electrostatic attraction. The adsorption was endothermic and spontaneous. The results demonstrated CTAB-MT was promising to separate uranium from ground water.
研究领域:
环境科学
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化学
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材料科学
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产品关联
DOI
高影响因子
AIP Advances
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2022
·Vol. 12
·期 8
·
IF 1.697
Wei Ming-Zhang,Deng Tian-Song,Zhang Qi,Chen Xi,Cheng Zhiqun,Li Shiqi,Gu Yi-Jie
The roles of CTAB and Ag + have been discovered and given us a deeper understanding of the seed-mediated method in the gold nanorods synthesis. Former work used binary surfactants CTAB + NaOL (sodium oleate) to greatly improve the dimensional tunability and monodispersity of gold nanorods. However, they only used a few of the concentration combinations of the binary surfactants, and the influence of NaOL under this method has not been systematically studied. In this work, we carried out systematic experiments under the variation of NaOL and used transmission electron microscopy and UV–vis-near-infrared spectroscopy to monitor the growth process of the gold nanorods. The results showed that the NaOL contributed to the symmetry breaking process. We discovered the ideal ranges of NaOL concentration under different concentrations of CTAB (10–40 mM). Lower concentrations of NaOL produced many impurities, such as Au spheres, while higher concentrations of NaOL led to the decrease of monodispersity of the obtained gold nanorods. A growth model based on the balance of diffusion/reduction of the growth solution has been proposed in order to explain the formation of the gold nanorods.
研究领域:
材料科学
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纳米技术
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化学
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Qi Ke,Xinyi Zhang,Yuan Yang,Qi Chen,Jianyu Su,Youhong Tang,Liming Fang
Magnetoelectric stimulation is a promising therapy for various disorders due to its high efficacy and safety. To explore its potential in chronic skin wound treatment, we developed a magnetoelectric dressing, CFO@CTAB/PVDF (CCP), by electrospinning cetyltrimethylammonium bromide-modified CoFe2O4 (CFO) particles with polyvinylidene fluoride. Cetyltrimethylammonium bromide (CTAB) serves as a dispersion surfactant for CFO, with its quaternary ammonium cations imparting antibacterial and hydrophilic properties to the dressing. Electrospinning polarizes polyvinylidene fluoride (PVDF) molecules and forms a fibrous membrane with flexibility and breathability. With a wearable electromagnetic induction device, a dynamic magnetic field is established to induce magnetostrictive deformation of CFO nanoparticles. Consequently, a piezoelectric potential is generated on the surface of PVDF nanofibers to enhance the endogenous electrical field in the wound, achieving a cascade coupling of electric–magnetic–mechanical–electric effects. Bacteria and cell cultures show that 2% CTAB effectively balances antibacterial property and fibroblast activity. Under dynamic magnetoelectric stimulation, the CCP dressing demonstrates significant upregulation of TGF-β, FGF, and VEGF, promoting L929 cell adhesion and proliferation. Moreover, it facilitates the healing of diabetic rat skin wounds infected with Staphylococcus aureus within 2 weeks. Histological and molecular biology evaluations confirm the anti-inflammatory effect of CTAB and the accelerated formation of collagen and vessel by electrical stimulation. This work provides insights into the application of magnetoelectric stimulation in the healing of chronic wounds.
研究领域:
生物医学工程
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材料科学
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伤口愈合
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生物材料
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纳米技术
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组织工程
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Wenjuan Wang,Yanfang Huang,Hongfei Ma,Lulu Kou,Bingbing Liu,Hu Sun,Shuzhen Yang,Guihong Han
Eutrophication of water bodies due to excessive phosphate release is becoming a serious issue. Herein, an Fe(III)-fulvic acid carrier with a synergistic effect with a surfactant was fabricated for the first time by a solvothermal method and evaluated for the removal of phosphate via an adsorption flotation strategy. This study indicated that the solvothermal method significantly improved the specific surface area, pore structure and active site distribution of the adsorption carrier and initially enhanced its adsorption performance. In addition, based on the synergistic effect of Fe(III)-fulvic acid and cetyltrimethylammonium bromide (CTAB), the competitive effect of surfactant and target ion in the adsorption flotation process was effectively broken. The theoretical maximum adsorption capacity of Fe(III)-fulvic acid increased from 169.205 ± 0.846 mg·g −1 to 274.725 ± 0.550 mg·g −1 after introducing CTAB, which was improved by 62.32% relative to the adsorption stage. FTIR and XPS analyses verified that the re-enhancement of the adsorption performance of the adsorbent carrier was mainly attributed to the chemisorption of CTAB with the carboxyl groups on the carrier surface, which intensified the electrostatic attraction and ligand exchange between the carrier and phosphate. Additionally, fractal and EDLVO theories revealed that CTAB could obviously improve the floatability of the carrier particles. Concurrently, the regeneration studies suggested that Fe(III)-fulvic acid possessed stable adsorption and flotation separation performance after three cycles. Overall, the Fe(III)-fulvic acid fabricated in this study not only realized the resource utilization of fulvic acid but also had practical application potential for the purification of oxyanions.
研究领域:
环境科学
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水处理
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化学工程
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材料科学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
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2019
·
IF 4.213
Haiyu Ni,Shuwen Xu,Pengfei Gu,Adelijiang wusiman,Yue Zhang,Tianxin Qiu,Zhenguang Liu,Han Ni,Yuanliang Hu,Jiaguo Liu,Yi Wu,Deyun Wang
This study aimed to optimize the preparation conditions for cetyltrimethylammonium bromide-modified Polygonatum sibiricum polysaccharide cubosomes (CTAB-modified PSP-Cubs) by response surface methodology (RSM). Glyceryl-monooleate (GMO) was used as the lipid base for the cubosomes. The optimal preparation conditions of CTAB-modified PSP-Cubs were as follows: the mass percentage of PSP to GMO (X 1 ), Poloxamer 407 (F127) to GMO (X 2 ) and water to GMO (X 3 ) was 1.4%, 9% and 50%, respectively. The encapsulation efficiency (EE) of CTAB-modified PSP-Cubs under the experimental conditions was 62.4 ± 3.6%, which was close to our predicted value. The particle size, polydispersity index (PDI) and zeta potential of CTAB-modified PSP-Cubs were 427.7 ± 8.0 nm , 0.236 ± 0.024 and 19.2 ± 0.4 mV, respectively. Specific modifications were able to slow down in vitro release behaviors and reduce cytotoxicity to some extent. The effects of CTAB-modified PSP-Cubs on splenic lymphocytes were also investigated. When splenic lymphocytes were treated with CTAB-modified PSP-Cubs together with LPS or PHA , the results showed more favorable effects on cellular proliferation than blank cubosomes or free PSP at certain concentrations.
研究领域:
药剂学
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免疫学
·
生物技术
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Han Lu,Mingliang Jin,Qilin Ma,Zhibin Yan,Zhenping Liu,Xin Wang,Eser Metin Akinoglu,Albert van den Berg,Guofu Zhou,Lingling Shui
In this work, we report a quick and controllable method for fabricating Ag nanoparticles (NPs) and nano-assemblies (NAs) on silicon (Si) surface via a galvanic reaction assisted by surfactant hexadecyltrimethylammonium bromide (CTAB). Obtained Si substrates with high density Ag NAs serve as surface-enhanced Raman scattering (SERS) substrates for unlabelled molecular sensing. The addition of CTAB enables not only the electromagnetic enhancement by controllable producing Ag NAs “hotspots”, but also the signal enhancement by enriching probe molecules via hydrophobic interaction. Two concentration regimes of 1.0 × 10 −8 –1.0 × 10 −11 M and 1.0 × 10 −12 –1.0 × 10 −16 M have been obtained for quantitative and qualitative detection of Rhodamine 6G (R6G) in aqueous solution, respectively. As a result, for determination of R6G, the quantitative and qualitative detection limits of 1.0 × 10 −11 and 1.0 × 10 −16 M have been obtained, respectively, with high reproducibility showing the relative standard deviation (RSD) of ∼7.3%. Simulation has been carried out using finite-difference time-domain (FDTD) to evaluate the dependence of electric field on the size and inter-gap of Ag NPs, showing good agreement with experimental results. The high sensitivity also enables SERS characterization of non-resonant and low Raman cross-section biomolecules, for example, amino acids. Such a fabrication process is simple, fast, cheap and reproducible; and therefore, it would be helpful to produce high sensitive SERS substrates to broaden their applications in chemical and biological fields for molecular diagnostics to single-/multiple-molecule detection.
研究领域:
材料科学
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分析化学
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纳米技术
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生物医学工程
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2020
·
IF 7.1
Mengdi Lu,Hu Zhu,Ming Lin,Fang Wang,Long Hong,Jean-Francois Masson,Wei Peng
Block copolymer (BCP) brush-like layer absorbed on optical fibers are shown to address the longstanding challenge of forming dense and well-dispersed gold nanorods (AuNRs) films on highly curved surface, allowing the development of real-time localized surface plasmon resonance (LSPR) biosensors for antigen-antibody interaction. This method requires only solution-based manufacturing processes and a plasma cleaning step to self-assemble AuNRs with various aspect ratios on the optical fibers. Because AuNRs capped with cetyltrimethylammonium bromide (CTAB) have been problematic for biosensing applications due to their cytotoxicity and displacement difficulty in the construction of biosensors, citrate-stabilized AuNRs were prepared from CTAB-stabilized AuNRs via surfactant exchange. For comparison, both a poly(styrene)- b -poly(acrylic acid) (PS- b -PAA) BCP template with CTAB-stabilized AuNRs and a poly(styrene)- b -poly(4-vinyl pyridine) (PS- b -P4VP) BCP template with citrate-stabilized AuNRs were employed for the fabrication of the optical fiber biosensor. The LSPR spectral analysis results demonstrate that the sensitivity of the sensor produced by the PS- b -P4VP templating method was 1.5 times better than that of the sensor produced by the PS- b -PAA templating method, which was due to the improved surface coverage and reduced aggregation of nanoparticles. The detection limit of the PS- b -P4VP-templated sensor for human IgG was 0.6 nM. Furthermore, for citrate-stabilized AuNRs, the PS- b -P4VP templating method also led to a better surface morphology and higher sensitivity as compared to the standard particle absorption methods using alkoxysilanes or polyelectrolytes on identical fibers. The simplicity of the fabrication process and the far superior optical performance of the PS- b -P4VP-templated LSPR optical fiber sensor illustrate the ability to regulate the detection range by tuning the aspect ratios of the AuNRs, and demonstrate its application prospects as a real-time biosensor without cytotoxicity.
研究领域:
材料科学
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纳米技术
·
光学传感
·
生物传感器
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产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 22
·18577-18582
·
IF 3.289
Yichang Yu,Zhangjun Hu,Yalei Zhang,Hongwen Gao
The title composite was synthesized under facile conditions by hydrolysis and co-precipitation. Through comparative studies, it was found that the morphology, structure and properties were affected by hexadecyl trimethylammonium bromide (CTAB) doping. Although the surface area decreases from 53.5 to 7.5 m2 g−1, it was found that CTAB@BiOCl exhibits higher adsorption capacity than the isolated BiOCl, and still maintains good photocatalytic activity, which is a little worse than the isolated BiOCl has. This was caused by the lower content of BiOCl in CTAB@BiOCl, which is less than 70%. The studies show that, in high concentrations of dye-contaminated water, the composite exhibits strong adsorption capacities of 901 mg g−1 to Congo Red (CR) and 699 mg g−1 to Reactive Red 3 (X3B). In the low-concentration case, it is able to process photocatalysis of those dyes. In the recycling experiment, the CTAB@BiOCl composite was regenerated in situ. And CTAB in the composite was almost completely degraded after five cycles, resulting in the regenerated BiOCl. Subsequently, the surface area of the composite increases from 7.5 to 22.62 m2 g−1, and along with this the adsorption capacities to CR and X3B decrease obviously due to the absence of the CTAB component. In addition, the photocatalysis activity of the generated composite has been promoted to be similar to the isolated BiOCl.
研究领域:
环境科学
·
材料化学
·
光催化
·
水处理
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DOI
高影响因子
ACS Omega
·
2021
·
IF 3.512
Qiming Zhuo,Wenli Liu,Hongxiang Xu,He Zhang,Xiaopeng Sun
Attachment behavior is a key component of flotation and has a decisive influence on flotation performance, and the experiment research on the attachment between mineral particles and bubbles still needs further research. In this work, a particle–bubble attachment apparatus and multiple target tracking software were developed. Coal particles were used as the subjects, and the effect of particle properties on the attachment performance was studied from the perspective of the particle group. The particle–bubble attachment experiments indicated that the collision position had an effect on the attachment efficiency, and the attachment efficiency decreased with an increase in the collision angle. The efficiency-weighted attachment angle was proposed to quantitatively describe the attachment performance of coal samples. The efficiency-weighted attachment angle of low-density coal samples was greater than that of high-density coal samples. For particles with different sizes, the efficiency-weighted attachment angle of fine particles was greater than that of coarse particles. Furthermore, SDS weakened the attachment performance between coal particles and bubbles via adsorption on the bubble, and the efficiency-weighted attachment angle decreased as the concentration of the SDS solution increased. CTAB adsorbed on coal particles and bubbles, and the efficiency-weighted attachment angle first increased and then decreased with increasing CTAB concentration.
研究领域:
矿物加工工程
·
表面化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）