MICROCHEMICAL JOURNAL
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2025
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IF 5.1
Lulu Cui,Weijie Shi,Houshen Li,Xiuxian Zhao,Shiyun Ai,Xiangju Meng,Shuhong Sun,Zeyi Guo
For bimetallic nanozymes, the closeness between the two elements is closely related to their properties, but achieving tight contact between the two components still faces challenges. Herein, copper was introduced by the coordination effect between the organic ligand in Ce-MOF and Cu 2+ , then a series of Cu-CeO 2 nanozymes were obtained by thermal treatment. The content of copper can be easily controlled and the spindle-shaped structure assembled by multilayer flakes can be obtained. The total antioxidant capacity (TAC) detection program based on the excellent peroxidase (POD)-like activity of the as-prepared Cu-CeO 2 nanozyme showed a wide linear detection range and ideal detection limits for ascorbic acid (AA), glutathione (GSH), Trolox and cysteine (Cys). More importantly, this method can be applied in TAC detection of commercial samples. This work provided a method for the design of high performance bimetallic nanozymes and developed a sensor that can be applied to detect TAC in vitamin C tablets and beverages.
研究领域:
材料科学
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生物医学工程
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分析化学
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
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IF 9.6
Yan Ge,Caiyi Fan,Qiyue Zhang,Hui Yang,Saisai Yuan,Bin Xu
In situ synthesis of S-scheme COF/Ce-MOF heterojunctions significantly enhances photocatalytic H 2 O 2 production under ambient conditions. The directional charge separation, precise band alignment, and synergistic dual active sites of the heterojunction enable efficient, stable, and selective H 2 O 2 generation. The CRM (Ce-MOF/COF) heterojunction delivers an H 2 O 2 yield that is 11.2-fold higher than pristine Ce-MOF and 3.1-fold higher than pure COF. Moreover, the CRM heterojunction maintains excellent productivity over a 6-h reaction period. In situ X-ray photoelectron spectroscopy (XPS) and density functional theory (DFT) analyses revealed not only the elemental composition and chemical states at the heterojunction interface but also the interfacial electronic redistribution and band alignment responsible for the enhanced photocatalytic performance. Specifically, the combined experimental and theoretical results confirmed the presence of strong interfacial coupling, the formation of an internal electric field, and the establishment of an S-scheme charge transfer pathway, all of which contribute to efficient charge separation and the preservation of high redox potentials, thereby enabling superior H 2 O 2 generation activity. Overall, this work not only deepens the understanding of MOF-based photocatalysts but also provides valuable design principles for constructing next-generation heterojunction materials with superior efficiency in photocatalytic H 2 O 2 production for environmental remediation.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2019
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IF 3.218
Xiaolong Tu,Yu Xie,Xue Ma,Feng Gao,Lei Gong,Dingwen Wang,Limin Lu,Guangbin Liu,Yongfang Yu,Xigen Huang
Metal–organic frameworks (MOFs) as porous materials have been widely used in electrochemical sensing field. Unfortunately, their low electrical conductivity and poor stability in the aqueous solution limit their application. To overcome these shortcomings, in this study, a novel reduced graphene oxide-encapsulated Ce-MOF (RGO@Ce-MOF) composite was synthesized by using a simple and green method. Ce-MOF and GO were firstly casted onto glassy carbon electrode, respectively, and then GO was reduced to RGO through electrochemical reduction strategy. The proposed encapsulated structure of RGO@Ce-MOF effectively improved the stability of Ce-MOF by preventing decomposition of MOF in solution. The combination of RGO and Ce-MOF can also significantly promote the conductivity of composite. Then, the obtained RGO@Ce-MOF composite was utilized as electrode material for the detection of dichlorophen (Dcp), a halogenated phenolic intermediate for synthesis of pesticide. The electrochemical properties of the proposed sensor were investigated by electrochemical techniques in detail. Benefiting from the synergy between Ce-MOF and RGO, the RGO@Ce-MOF can be used to detect Dcp with a wide linear range from 0.02 μM to 10 μM and a low detection limit of 0.007 μM (S/N = 3). Furthermore, the RGO@Ce-MOF electrode showed acceptable reproducibility and good selectivity. This method was applied to detect Dcp in the real samples with satisfying results.
研究领域:
材料科学
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环境科学
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分析化学
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DOI
高影响因子
ANALYTICA CHIMICA ACTA
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2025
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IF 6
Yimeng Li,Jiayao Wang,Yi Ran,Yiwei Liu,Xiaopeng Hu
Background A dual-mode fluorescence/colorimetric aptasensor was developed for the sensitive detection of isocarbophos, an organophosphorus pesticide posing significant public health risks. Using Zn,Ce-MOF nanocomposites, this sensor integrated magnetic separation and signal amplification. This integrated biosensing strategy offers a promising tool for environmental safety assurance and food quality control applications. Results The Zn,Ce-MOF nanozyme of this sensor serves as both a carrier of 3,3′,5,5′-tetramethylbenzidine (TMB) and oxidase mimic, facilitating enzyme-free TMB oxidation. The dual-readout system enables self-validating detection through independent channels (fluorescence LOD: 0.06 ng mL −1 ; colorimetric LOD: 0.09 ng mL −1 ), with robust performance, high interferent selectivity, and reproducibility. Practical validation in spiked agricultural samples yielded recovery rates of 97.7–113.6 %, confirming the platform's suitability for field-deployable pesticide monitoring. Significance This work developed a fluorescence/visual aptasensor with self-assembled TMB/Au/Zn,Ce-MOF probes for one-step magnetic separation dual-mode detection. This integrated biosensing strategy improves detection efficiency and accuracy, offering a general strategy for multimodal biosensors.
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Polymers
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2024
·Vol. 16
·期 12
·1747
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IF 4.7
Qi Cheng,Xiaoyu Du,Zuyao Fu,Zhaoyang Ding,Jing Xie
Increasing concern over the safety of consumable products, particularly aquatic products, due to freshness issues, has become a pressing issue. Therefore, ensuring the quality and safety of aquatic products is paramount. To address this, a dual-mode colorimetric–fluorescence sensor utilizing Ce-MOF as a mimic peroxidase to detect H2S was developed. Ce-MOF was prepared by a conventional solvothermal synthesis method. Ce-MOF catalyzed the oxidation of 3,3’,5,5’-tetramethylbenzidine (TMB) by hydrogen peroxide (H2O2) to produce blue oxidized TMB (oxTMB). When dissolved, hydrogen sulfide (H2S) was present in the solution, and it inhibited the catalytic effect of Ce-MOF and caused the color of the solution to fade from blue to colorless. This change provided an intuitive indication for the detection of H2S. Through steady-state dynamic analysis, the working mechanism of this sensor was elucidated. The sensor exhibited pronounced color changes from blue to colorless, accompanied by a shift in fluorescence from none to light blue. Additionally, UV–vis absorption demonstrated a linear correlation with the H2S concentration, ranging from 200 to 2300 µM, with high sensitivity (limit of detection, LOD = 0.262 μM). Fluorescence intensity also showed a linear correlation, ranging from 16 to 320 µM, with high selectivity and sensitivity (LOD = 0.156 μM). These results underscore the sensor’s effectiveness in detecting H2S. Furthermore, the sensor enhanced the accuracy of H2S detection and fulfilled the requirements for assessing food freshness and safety.
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Analytical Methods
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2024
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IF 2.7
Tongxiao Zhao,Baokang Jin
Carbohydrate antigen 19-9 (CA19-9) is an important marker for pancreatic cancer, ovarian cancer and other tumors, and its rapid and stable detection is the basis for early diagnosis and treatment. In this paper, a label-free electrochemical immunosensor for the sensitive detection of CA19-9 has been developed. First, the synthesis of two novel core–shell bimetallic nanomaterials, namely Ce-MOF-on-Fe-MOF and Fe-MOF-on-Ce-MOF, was accomplished using the MOF-on-MOF approach. The poor electrical conductivity of MOF materials was addressed by incorporating polyethylenimide (PEI) functionalized rGO with Ce-MOF-on-Fe-MOF and Fe-MOF-on-Ce-MOF nanomaterials. Simultaneously, toluidine blue (Tb) was employed as a redox probe and physically adsorbed onto the synthesized materials, resulting in the formation of two nanomaterials: rGO@Ce-MOF-on-Fe-MOF@Tb and rGO@Fe-MOF-on-Ce-MOF@Tb. The fundamental characterization reveals that the sensing performance of the rGO@Ce-MOF-on-Fe-MOF@TB-based immune sensor surpasses that of the rGO@Fe-MOF-on-Ce-MOF@TB-based immune sensor, which is attributed to the fact that, unlike the interlayer-constrained structure of Fe-MOF-on-Ce-MOF, in Ce-MOF-on-Fe-MOF, Ce-MOF penetrates into Fe-MOF to form a heterogeneous structure due to the relatively large pore size of Fe-MOF, which better combines the excellent biocompatibility and strong anchoring effect of Fe MOFs on antibodies, as well as the high electrochemical activity and conductivity of Ce-MOF, to enhance sensing performance. The proposed label-free immunosensor based on rGO@Ce-MOF-on-Fe-MOF@Tb has a wide linear range (1–100 000 mU mL−1), a low detection limit (0.34 mU mL−1), good stability, reproducibility, and repeatability, and satisfactory applicability, which provides a potential platform for clinical applications.
研究领域:
肿瘤学
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生物传感技术
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材料科学
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Biomaterials Advances
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2026
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IF 6.7
Yuhang Zhang,Jingxu Wang,Weiming Yu,Yuting Zhang,Jiaxin Jiang,Yu Chen,Zhe Ji
BA@Ce-MOF exhibits SOD/CAT-like enzyme activities and antioxidant effects. • In situ formation of hydrogel via thiol-ene photo-click chemistry reaction. • The ROS-responsive oxidation of thioether bonds in the hydrogel network accelerates drug release. • Promotes osteogenesis, angiogenesis, and M2 macrophage polarization in vivo. The hyperglycemic and reactive oxygen species (ROS)-rich microenvironment in diabetes readily incites inflammation, and the persistent inflammation exacerbates bone resorption, severely hindering the repair of diabetic alveolar bone defects. The alendronate used in clinical practice can inhibit bone resorption but lacks osteoinductive activity and cannot modulate the inflammatory milieu; traditional Chinese medicine monomers possess anti-inflammatory potential but are limited by low bioavailability. Herein, we developed a multifunctional nanocomposite hydrogel via a hierarchical integration strategy using carbon dots and Ce-MOF nanozymes to promote diabetic alveolar bone repair. In this system, the Ce-MOF, exhibiting superoxide dismutase (SOD)-and catalase (CAT)-like activities, scavenges ROS and enables the sustained release of carbon dots composed of alendronate and baicalin, achieving synergistic antioxidant and antibacterial effects. The hydrogel, formed from vinyl-group-grafted chitosan and thiolated sodium alginate via rapid in situ photoclick chemistry, adapts to irregular defect shapes; the thioether bonds formed in its crosslinked structure enable ROS-triggered acceleration of BA@Ce-MOF nanoparticle release. In vitro, the BA@Ce@CSSA hydrogel demonstrated excellent biocompatibility. Its SOD/CAT activities and the antioxidant function of the monomer synergistically eliminated ROS and induced macrophage M2 polarization for immunomodulation. Concurrently, it enhanced osteogenic differentiation by upregulating RUNX2 and OPN expression. In vivo, Micro-CT and histomorphometric analyses confirmed that BA@Ce@CSSA significantly accelerated and improved the quality of bone regeneration. In summary, this study presents a hierarchically designed therapeutic strategy that effectively promotes bone regeneration by integrating antioxidant, anti-inflammatory, pro-angiogenic, and pro-osteogenic functions within a ROS-responsive hydrogel system, offering a promising approach for treating alveolar bone defects under diabetic conditions.
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高影响因子
JOURNAL OF CATALYSIS
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2025
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IF 6.5
Juan Chen,Linmeng Wang,Hongyi Gao,Rushuo Li,Zhiyuan Liu,Tao Ban,Shunzheng Zhao,Jichao Yang,Ge Wang
Single-atom catalysts (SACs) catalysts have unique electronic properties and geometric structures, offering maximum atom-utilization efficiency. Noble metal-free SACs anchored within metal–organic frameworks (MOFs) enable precise tuning of electronic structures and significantly enhance catalytic activity beyond conventional porous materials. Herein, we synthesized the synthesis of Cu(I)/Ce-MOF-808-EA by anchoring atomically dispersed Cu(II) species onto the open Ce 6 nodes of the Ce-MOF-808 framework, followed by in situ reduction to Cu(I) via ethanol treatment and thermal activation processes. The atomic dispersion and valence transformation of Cu sites on Ce-MOF-808 were confirmed by X-ray Absorption Spectroscopy (XAS), high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM), and X-ray photoelectron spectroscopy (XPS). The resulting Cu(I)/Ce-MOF-808-EA exhibited outstanding catalytic performance for the hydrogenation of Dicyclopentadiene (DCPD), achieving 100 % conversion, 91.54 % selectivity toward Dihydrodicyclopentadiene (DHDCPD), and 8.45 % selectivity toward Tetrahydrodicyclopentadiene (THDCPD) at 100 °C, 2 MPa. Notably, Cu(I)/Ce-MOF-808-EA outperformed other transition metal catalysts (Co/Ce-MOF-808-EA, Ni/Ce-MOF-808-EA and Zn/Ce-MOF-808-EA). For the first time, Density Functional Theory (DFT) calculations, combined with experimental investigations, revealed a low-energy reaction pathway for DCPD hydrogenation, wherein Cu(I) sites, in cooperation with adjacent oxygen atoms, act as bi-active centers to heterolytically cleave H 2 into proton and hydride species (*H δ+ -H δ- ) for subsequent hydrogenation. This study underscores the potential of MOFs as versatile platforms for engineering single-atom catalysts with enhanced catalytic properties.
研究领域:
化学
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材料科学
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催化
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高影响因子
ELECTROCHIMICA ACTA
·
2025
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IF 5.6
Zhenwu Zhong,Min Liu,Zhaoxiang Qi,Ying Wang,Wenjun Zhang,Yan Zhang,Ying Qi,Hongyu Mi,Jian Cheng,Shu Yin,Yahong Xie
This study presents a facile synthesis of cerium-based metal–organic frameworks (Ce-BTC) and their subsequent pyrolysis into nanorod-shaped CeO 2 -BTC for interfacial engineering in carbon-based perovskite solar cells (C-PSCs). The optimized FTO/SnO 2 /CH 3 NH 3 PbI 3 /CeO 2 -BTC/Carbon architecture achieves a maximum power conversion efficiency (PCE) of 14.63%, representing a 31.09% enhancement over the baseline device. This improvement stems from multiple synergistic effects: CeO 2 -BTC demonstrates exceptional charge extraction capability, establishes superior interfacial contact, and directly coordinates with perovskite through Pb-O bond formation. Furthermore, the C=O groups effectively anchor uncoordinated Pb 2 + ions, modulating perovskite crystallization kinetics and improving film quality. Subsequent hot-pressing treatment elevates the champion device PCE to 15.12% through enhanced interfacial compactness. Remarkably, the optimized devices retain 93.26% of initial efficiency after 700 h of ambient air exposure without encapsulation, demonstrating exceptional environmental stability. This work provides a comprehensive strategy for developing high-performance, durable carbon-based perovskite photovoltaics through rational interface engineering.
研究领域:
材料科学
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纳米技术
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光伏技术
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化学工程
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高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2025
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IF 4.6
Xinzhuang Wei,Yaming Zhao,Huifeng Zhang,Qiong Jia
With the extensive use of neonicotinoid pesticides like thiamethoxam (TMX), there is a growing need to develop sensitive and selective methods to monitor its residue levels. In this study, we developed a fluorescence sensor based on terbium/cerium metal-organic framework combined with molecularly imprinted polymer (Tb/Ce MOF@MIP) for TMX detection. Through systematic optimization of synthesis conditions and detection conditions, the sensor was successfully employed for the determination of TMX, exhibiting high selectivity, along with a linear detection range of 1–50 μM and a limit of detection of 0.8 μM. In addition, the practical applicability of the sensor was validated in real samples including apples, tea, and soil, and the accuracy was assessed through recovery experiments.
研究领域:
分析化学
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环境监测
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食品安全
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材料科学
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农药残留检测
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PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Tengru Xie,Luwei Wang,Hexiang Wang,Chuan Cao,Chenliu Tang,Xiang Hu
Antibiotics cannot be completely removed through traditional treatment technologies, leading to their accumulation in the aquatic environment and posing a serious threat to human health. MOF-derived carbon is a promising material for the degradation of antibiotics. Herein, in this study, a novel Co/Ce-MOF electrode was rapidly prepared by one-step electrodeposition at room temperature. Then the Co/Ce-MOF electrode was carbonized to obtain MOF-derived carbon composite electrode (Co/Ce-C350Air). The ceftazidime (CAZ) degradation efficiency achieved 96.59% within 60 min under the optimum conditions ([CAZ] = 5 mg/L, [Na 2 SO 4 ] = 50 mM, current density = 0.8 mA/cm 2 , electrode gap = 2 cm and initial pH = 5.6) and the degradation process of CAZ conformed to first-order reaction kinetics. Furthermore, the removal efficiency of CAZ maintained at 94.92% even recycling for 6 times, demonstrating the good electrochemical stability of the Co/Ce-C350Air composite anode. The synergistic effect between Co and Ce metals improved the catalytic performance and stability of the Co/Ce-C350Air electrode. Radical quenching experiments and electron paramagnetic resonance (EPR) spectra results revealed that surface hydroxyl radicals were the main active species in the degradation of CAZ. The main intermediate products were identified by high-performance liquid chromatography-mass spectrometry (HPLC-MS) and the possible degradation pathway was proposed. In addition, toxicity tests with Ecological Structure Activity Relationships (ECOSAR) software results indicated that the toxicity of the intermediate products was lower than that of CAZ. This work provided a safe and effective strategy for the degradation of antibiotics in the electrochemical oxidation system.
研究领域:
环境科学
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材料科学
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电化学工程
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高影响因子
CATALYSIS COMMUNICATIONS
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2023
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IF 3.7
Lirong Lv,Zhongguo Zhang,Sheng Wang,Yue Shan,Liangliang Wang,Tongzhou Xu,Peiran He
A series of Y Ce catalysts were prepared using Y-loaded (Y = Cu, Co, Mn) Ce-based metal–organic framework as a precursor. Mn-loaded CeO 2 exhibited significantly better catalytic activity in the catalytic oxidation of ethyl acetate (EA) than noble metal catalyst. The relationship between the physicochemical properties of Y Ce catalysts and catalytic activity was studied by different characterization methods. The enhanced catalytic activity was attributed to the strong interaction between the transition metals and Ce, high specific surface area, abundant lattice defects, more oxygen vacacies and higher O latt /(O latt + O ads + O w ) molar ratios. The main intermediates in the oxidation of EA were ethanol, acetic acid, acetone, acetaldehyde and diethyl ether.
研究领域:
化学
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材料科学
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高影响因子
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