APPLIED SURFACE SCIENCE
·
2026
·
IF 6.9
Yifei Huang,Hongliang Dai,Hongye Bai,Weiqiang Fan
Biomass materials as an abundant renewable resource could replace traditional fossil fuels and non-renewable materials, providing a new solution to achieve sustainable development. In this paper, Ce-modified Co(OH) 2 /Cu 2 O composite catalysts were prepared by an electrodeposition method, and the CoOOH/CuOOH dual active sites were successfully obtained through an electrochemical reconfiguration strategy, and the experimental results showed that the incorporation of Ce induced the formation of high-valent Co and Cu species, which improved the activity of electrocatalytic HMF oxidation. At 0.55 V vs Hg/HgO, the HMF conversion reached 100%, the FDCA yield was 95.04% and the Faraday efficiency was up to 98.47%. These results confirm the effectiveness of Ce-based non-precious metal catalysts in electrochemical reconstruction strategies and demonstrate their potential application in the high-value conversion of biomass derivatives. This finding not only provides a solid research basis for the development of highly efficient catalysts, but is also expected to promote the development of related technological fields.
✓ 已验证
产品关联
DOI
高影响因子
Food Bioscience
·
2024
·
IF 4.8
Hua-Wei Zhang,Ke Cheng,Jing-Jing Tang,Ling-Zhi Liu,Ruo-Xuan Qin,Yi-Nuo Sun,Jiang-Hua Zhang,Da-Yong Zhou
To synthesize structured phospholipids (SPLs) in an efficient and green manner is of great significance. Herein, novel Fe 3 O 4 @SiO 2 - Aspergillus oryzae lipase (AOL)/copper phosphate trihydrate nanoflowers (FLCNs) were prepared by coprecipitation method and then characterized by energy-dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, and vibrating sample magnetometer etc. FLCN activity was further evaluated by promoting functional medium-chain SPL (MCSPL) or short-chain SPL (SCSPL) synthesis via biotransesterification between soybean lecithins and medium-chain fatty acids (MCFAs) or short-chain fatty acids (SCFAs) under optimal reaction conditions. Moreover, FLCNs and free AOLs were comparatively assayed in enzymatic properties. As a result, FLCNs were successfully fabricated with sufficiently large surfaces and numerous enzyme active sites. Owing to these structural features, after reacting at 40 °C for 36 h with FLCN dosage of 6% and substrate mass ratio of 1:3:3, FLCNs exhibited much more excellent activity in MCSPL synthesis with 88.30 ± 0.63% of MCFA incorporation than benchmark enzymes and heterogeneous functional materials. Most significantly, in the first biosynthesis of functional SCSPLs facilitated by FLCNs, much superior SCFA incorporation of 66.55 ± 0.73% was obtained. Notably, FLCNs also possessed convenient magnetic separability together with superior pH and temperature tolerances, thermal and storage stabilities, and recyclability to free AOLs. In brief, the present investigation provides a new biological strategy for effective, economic, convenient, and eco-friendly SPL synthesis in food and pharmaceutical industries, highlighting its merits in functional lipid production.
研究领域:
食品科学
·
生物工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Nano Research
·
2023
·
IF 9.9
Yang Limin,Qu Linjiao,Zhang Xiaolong,Li Mingming,Liu Zhen
Enzyme-inorganic hybrid nanoflowers (HNFs) have shown excellent sensing capabilities due to their large specific surface area as well as the simplicity and mildness of the preparation process. However, coupling HNFs to electrodes to fabricate a uniform and controllable enzymatic electrochemical sensing interface remains a challenge. Here, we proposed an aptamer-induced in-situ fabrication strategy for preparing an HNF-based electrochemical sensor with ideal performance. Central to this strategy is the introduction of acetylcholinesterase (AChE)-specific binding aptamer (Apt), which induces the in-situ growth of AChE-copper phosphate (Cu 3 (PO 4 ) 2 ) HNFs on the surface of carbon paper (CP). In addition, a dense gold nanoparticle (AuNP) layer was electrodeposited on the CP for anchoring Apt and further extending the electroactive surface area. The prepared AChE-Cu 3 (PO 4 ) 2 HNF/Apt/AuNP/CP biosensor exhibited a wide detection range from 1 to 10 7 pM for the four organophosphorus inhibitors, including isocarbophos, dichlorvos, methamidophos, and parathion, with detection limits down to 0.016, 0.028, 0.071, and 0.113 pM, respectively. With the reactivation of pralidoxime chloride, the electrode can still recover 98.1% of the response after five times of repeated use. In real sample detection, the biosensor achieved high recoveries from 96.45% to 100.13%. The detection target may be extendable to other AChE inhibitors (e.g., drugs for Alzheimer’s disease). This study demonstrates for the first time the feasibility of using aptamers as an inducer to fabricate an electrochemical enzyme sensing interface in-situ . This strategy can be used to fabricate other enzyme-based biosensors and therefore has broader applications.
研究领域:
分析化学
·
生物传感器
·
电化学
·
纳米技术
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Xian Jiang,Bing Liu,Qinghong Zeng,Fuchao Yang,Zhiguang Guo
To alleviate the economic and environmental damage caused by industrial discharges of oily wastewater, materials applied for efficient oil/water separation are receiving significant attention from researchers and engineers. Among others, switchable wettable materials for bidirectional oil/water separation show great potential for practical applications. Inspired by mussels, we utilized a simple immersion method to construct a polydopamine (PDA) coating on a peony-like copper phosphate surface. Then, TiO2 was deposited on the PDA coating surface to build a micro–nano hierarchical structure, which was modified with octadecanethiol (ODT) to obtain a switchable wettable peony-like superhydrophobic surface. The water contact angle of the obtained superhydrophobic surface reached 153.5°, and the separation efficiency was as high as 99.84% with a flux greater than 15,100 L/(m2·h) after 10 separation cycles for a variety of heavy oil/water mixtures. Notably, the modified membranes have a unique photoresponsiveness, transforming to superhydrophilic upon ultraviolet irradiation, achieving separation efficiencies of up to 99.83% and separation fluxes greater than 32,200 L/(m2·h) after 10 separation cycles for a variety of light oil/water mixtures. More importantly, this switch behavior is reversible, and the high hydrophobicity can be restored after heating to achieve efficient separation of heavy oil/water mixtures. In addition, the prepared membranes can maintain high hydrophobicity under acid–base conditions and after 30 sandpaper abrasion cycles, and damaged membranes can be restored to superhydrophobicity after a brief modification in the ODT solution. This simple-to-prepare, easy-to-repair, robust membrane with switchable wettability shows great potential in the field of oil/water separation.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Jiadong Chen,Xiao Song,Yinna Wu,Junwei Zhu,Wenbin Liu
BSA@Cu 3 (PO 4 ) 2 hybrid nanoflower as nanozyme with tyrosinase mimic activity. • Salt hydrate Na 2 CO 3 ·10H 2 O as essential cofactor for catalysis in organic solvent. • High catalytic performance for oxidation diphenol to o-quinone. • N Cu coordination as nucleation sites for HNF and active sites tyrosinase mimetics. • Production of melanin-like amino acid surfactants from ethyl caffeate. Amino acid surfactants are widely used in daily life and food industry. Melanin-like amino acid surfactant (MLAAS) is a novel type surfactant. Herein, a robust nanozyme with tyrosinase mimetic activity was first developed by fabricating BSA@Cu 3 (PO 4 ) 2 organic-inorganic hybrid nanoflower (HNF) using bovine serum albumin and copper ions as an organic and inorganic components, respectively. HNF nanozyme biomimetically oxidized ethyl caffeate to o-quinone, achieving yield of 59.57% in organic solvents with Na 2 CO 3 ·10H 2 O as essential cofactor. Michaelis constant was 15.05 mM and turnover number was 6.32 s −1 . It exhibited broad substrate scope toward diphenols and outstanding stability in various organic solvents. o-Quinone was conjugated with leucine to produce MLAAS, which possessed excellent emulsifying and foaming capacities with a critical micelle concentration of 8.12 mM. It presents a novel strategy by combination of HNF and salt hydrate for production of amino acid surfactant with promising emulsification and foaming potential in food processing. Download: Download high-res image (144KB) Download: Download full-size image
✓ 已验证
DOI
PubMed
高影响因子
TALANTA
·
2023
·
IF 6.1
Chen Cui,Xinyao Lin,Jie Lv,Hang Guo,Lu Shen,Guoqiang Xiang,Wenjie Zhao,Dechen Jiang
Designing innovative electrochemiluminescence (ECL) immunosensors is critical for the detection of biomarkers with a low concentration and the precise evaluation of clinical diseases. Herein, a Cu 3 (hexahydroxytriphenylene) 2 (Cu 3 (HHTP) 2 ) nanoflake-based sandwich-type ECL immunosensor was constructed for C-Reactive Protein (CRP) detection. The Cu 3 (HHTP) 2 nanoflake , an electronically conductive metal–organic framework (MOF), has a periodically arranged porous structure with a cavity size of 2 nm, which not only accommodates a large amount of Ru(bpy) 3 2+ but also confines the spatial diffusion of active species. Therefore, the Ru(bpy) 3 2+ -loaded Cu 3 (HHTP) 2 nanocomplex (Ru@CuMOF) as an ECL emitter exhibits an enhanced ECL efficiency. The ECL resonance energy transfer (ECL-RET) was accomplished by combining Ru@CuMOF used as a donor with gold nanoparticles-functionalized graphene oxide nanosheets (GO-Au) utilized as an acceptor. This should be ascribed to the fact that the ECL emission spectrum of Ru@CuMOF shows the strongest signal intensity at 615 nm, overlapping with the absorption spectrum of GO-Au at 580–680 nm. Targeted detection of CRP in human serum samples was achieved by the sandwich-type immunosensor based on the ECL-RET mechanism with a 0.26 pg mL −1 detection limit. The electro-activated hybrids of Cu 3 (HHTP) 2 and ECL emitters provide a new sensing strategy for the high-sensitivity detection of disease markers.
研究领域:
生物医学工程
·
分析化学
·
临床诊断
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Lei Wang,Yuanyuan Liu,Juan Han,Yihan Liu,Huiling Lan,Chunmei Li,Yun Wang
Enzyme-nanoMOFs, a very recent and emerging green biocatalyst, has been widely researched to pursue the improvement of enzyme stability. However, MOFs coating decreases substrate accessibility and possesses nanometer size, thus restraining enzyme activity and controllable recycling. Here, inspired by natural biomineralization , we created a morphology-dependent intelligent [email protected] biocatalyst via rationally in situ tailoring the morphology of enzyme-nanoMOFs for enhancing the combination of substrate aptamers. The resulting [email protected] nanoflowers achieved an “on-demand” tuning of functionality, where self-enriching substrate by substrate aptamers acted in synergy with [email protected] enzyme mimics to significantly boost catalytic activity during biocatalysis. Moreover, after completing the catalytic reaction , easily magnetic separation and then competitive release to automatically start the cyclic catalysis were provided by automatic structure switch of aptamer-cDNA hybridization and aptamer-substrate binding. The degradation of BPA with laccase-Cu 3 (BTC) 2 @P1 reached 4.4-fold improvement in the catalytic efficiency. Laccase-Cu 3 (BTC) 2 @P1 could be controllably recycled to retain 76% initial activity after 8 catalytic cycles. These catalytic and recyclable performances were much better than laccase-Cu 3 (BTC) 2 . The combination of the unique morphology of enzyme-nanoMOFs and performance of aptamers brings hope for the industrial application of intelligent [email protected] systems.
研究领域:
生物技术
·
纳米技术
·
催化
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 48
·期 1
·228-236
·
IF 3.3
Yan Wang,Haoran Li,Daqing Chen,Danhua Ge,Xiaojun Chen
Herein, a simple solvothermal method was used to prepare a CuSx/g-C3N4 (CSG) heterojunction as an efficient oxygen activator containing sulfur vacancies (SVs). The as-prepared catalyst can activate oxygen to effectively degrade tetracycline (TC). The degradation rate of TC (20 mg L−1) reached 98.9% in 90 min over CSG (0.02 g L−1) under an air atmosphere, which maintained good performance within a wide pH range of 6–10. It was almost unaffected by any light source and water quality, indicating a highly efficient oxygen activator and good stability. Moreover, the trapping experiments and EPR results revealed that the main reactive oxygen species (ROSs) were singlet oxygen (1O2) and hydroxyl radicals (˙OH). CSG (4 : 1) enabled the activation of oxygen-produced ROS for removing TC even in the dark, which was in accordance with the EPR results. In addition, the CSG catalyst exhibited a good removal performance in practical wastewater treatment. Our study demonstrated that the CSG catalyst had the potential to remove organic pollutants from wastewater.
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 11
·2413
·
IF 4.2
Shi Wang,Ping Li,Junyi Wang,Jun Gong,Helin Lu,Xiaobo Wang,Quan Wang,Ping Xue
The realization of efficient and accurate detection of biomolecules has become a key scientific issue in the field of life sciences. With the rapid development of nanotechnology, electrochemical sensors constructed from the superior physical and chemical properties of nanomaterials show faster and more accurate detection. Among nanomaterials, two-dimensional conductive MOF (2D cMOF) is considered to be a star material in electrochemical sensors due to its remarkable conductivity, high porosity, and stability. In this paper, a Cu3(HHTP)2/SPE electrochemical sensor for the detection of ascorbic acid (AA) was constructed by modifying 2D cMOF (Cu3(HHTP)2) on the surface of the screen-printed electrode (SPE). The sensor exhibited excellent catalytic activity in the detection of AA, with a lower detection limit of 2.4 μmol/L (S/N = 3) and a wide linear range of 25–1645 μmol/L. This high catalytic activity can be attributed to the abundant catalytic sites in Cu3(HHTP)2and the rapid electron transfer between Cu+and Cu2+, which accelerates the oxidation of AA. This work lays a foundation for the subsequent development of MOFs with special electrochemical catalytic properties and the integration of 2D cMOF into intelligent electrical analysis devices.
研究领域:
纳米技术
·
电化学
·
生物传感器
·
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Di Yang,Jie Cai,Md Rayhan,Qiuping Fu,Lulu Xiong,Danping Chen,Zhenchao Wang,Bingqian Liu
First application of Cu 3 (BTC) 2 -based composite as a photoelectrochemical platform for trace-level lead ion detection. • Synergistic integration of DNAzyme amplification and exciton-plasmon interaction for enhanced sensitivity. • A Weighted Least Squares (WLS)-based calibration framework to minimize matrix effects, ensuring reproducible and reliable outcomes. The accurate monitoring of lead ions (Pb 2+ ) in complex environmental matrices demands ultrasensitive and robust sensing technologies. Herein, we engineer a DNAzyme-driven “signal-on” photoelectrochemical (PEC) aptasensor based on a precisely controlled layer-by-layer self-assembled TiO 2 /Cu 3 (BTC) 2 hierarchical architecture. By exploiting the spatial precision of this architecture, we position Au nanoparticles (AuNPs) in optimal proximity to the Cu 3 (BTC) 2 framework to facilitate efficient exciton-plasmon interaction (EPI)-mediated photocurrent quenching. Target Pb 2+ triggers the specific cleavage of substrate DNA (sDNA), detaching the Au/PAMAM-hairpin DNA conjugates, thereby restoring the photocurrent proportionally to Pb 2+ concentration. This self-assembled platform achieves exceptional sensitivity with a broad linear range (10 −12 to 10 −6 mol/L) and an ultralow detection limit of 0.97 pM. Crucially, to mitigate heteroscedasticity and matrix interference, a weighted least squares (WLS) calibration model is integrated, which assigns higher statistical weights to low-concentration measurements, significantly enhancing quantitative reliability. The sensor demonstrates satisfactory recoveries in real water samples, establishing a standardized and robust paradigm for trace heavy metal monitoring. This study develops a DNAzyme-driven signal-on PEC aptasensor for trace Pb 2+ detection. A novel Cu 3 (BTC) 2 composite serves as the first PEC substrate for this application. It enhances charge separation efficiency. The sensor synergistically integrates exciton-plasmon interaction with DNAzyme amplification for dual signal enhancement. A WLS-based calibration framework is also incorporated. It standardizes signal processing, mitigates matrix effects, and ensures reproducible quantification in real water samples. Download: Download high-res image (109KB) Download: Download full-size image
✓ 已验证
DOI
高影响因子
TALANTA
·
2026
·
IF 6.7
Zihao Zhao,Jianlong Li,Jinmi Zhang,Qiang Li,Sheng Li,Yingbo Shi,Xiaoli Xiong
The simultaneous determination of dopamine and uric acid in complicated biological matrices remains challenging due to overlapping electrochemical signals and interference from coexisting species. Herein, a machine learning-assisted electrochemical sensor based on a Cu 3 (HHTP) 2 /COOH-MWCNTs hybrid is developed for the simultaneous determination of these analytes. Benefiting from the unique π-π stacking and π-d conjugation characteristics of Cu 3 (HHTP) 2 , as well as the excellent coordination effect between COOH-MWCNTs and Cu 2+ and the good dispersibility of carbon nanotubes themselves, the composite material exhibits more prominent surface activity, significantly boosting the exposure of active sites and accelerating the electron transfer kinetics at the electrode-electrolyte interface. On this basis, we constructed an electrochemical sensing platform for the simultaneous detection of DA and UA in human serum samples. The sensor show excellent performance with dual linear ranges of 0.5–15 and 15–80 μM for DA, and 1–200 and 200–350 μM for UA, achieving low LODs of 0.039 μM and 0.083 μM, respectively (S/N = 3). Furthermore, machine learning (ML) algorithms were employed to optimize electrochemical signal processing, enabling more accurate and robust analysis of complex data. The proposed approach achieved successful application in the simultaneous determination of DA and UA in human serum matrix samples.
✓ 已验证
DOI
PubMed
高影响因子
APPLIED CATALYSIS A-GENERAL
·
2020
·
IF 5.006
Xu Yang,Wu Liu,Fenghua Tan,Zhaoxia Zhang,Xindi Chen,Tengda Liang,Chuande Wu
Catalyst deactivation caused by the metal sintering/leaching is still a great challenge confronted by the scientists. Herein, we report a robust strategy to in situ synthesize mesoporous silica supported highly dispersed copper catalyst by homogeneously hybridizing the silica and metal-organic framework (MOF) copper benzene-1,3,5-tricarboxylate (Cu 3 (BTC) 2 ). We find the introducing silica is the key to the formation of homogeneous hybridization by regulating the growth of Cu-BTC crystallite, yielding various metal dispersion and reducibility during calcination; while the added BTC ligands acts as porous initiator, promoting the accessibility of copper centers for reactants. The optimized CuO#SiO 2 – s1 with molar ratio Cu/Si of 0.23, exhibits excellent catalytic performance towards the furfural hydrogenation, showing a high activity as 9.2 mol FF mol Cu −1 h −1 , nearly 100 % furfural alcohol selectivity and minimized activity decline (<5%) after 5 repeated run. This work could open up a new avenue for the synthesis of mesoporous silica supported highly dispersed metal catalyst for hydrogenation.
研究领域:
化学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）