FOOD CHEMISTRY
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2025
·
IF 9.8
Xingyu Wang,Pingping Liu,Haijie Ca,Cheng Zhao,Weihao Wu,Haixia Zhou,Yayao Song,Zhaohuan Zhang,Yong Zhao,Yongheng Zhu
Listeria monocytogenes ( LM ) , a foodborne pathogen renowned for its cold tolerance, often poses a contamination threat to dairy products, underscoring the urgent need for rapid detection methods to prevent outbreaks. Herein, urchin-like WO 3 nanostructures modified with Ag nanoparticles are employed to construct a highly active surface, which exhibits excellent sensing performance for 3-hydroxy-2-butanone (3H2B), a characteristic biomarker of LM . The 1.0 wt% Ag-WO 3 -based sensor characterized by high sensitivity (R a /R g = 92.7@30 ppm 3H2B), satisfactory repeatability, and potential for practical applications. Furthermore, confirmed that the chemical sensitization effect of Ag nanoparticles significantly reduces reaction activation energy. The developed gas sensor achieves highly accurate detection of LM at trace concentrations in dairy products. These insights could pave the way for the development of more efficient food safety diagnostics, ultimately contributing to enhanced public health protection.
研究领域:
食品安全
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生物传感器
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纳米材料
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微机电系统（MEMS）
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分析化学
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产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2016
·Vol. 183
·期 3
·1107-1114
·
IF 4.831
Sun Xue-cheng,Lei Chong,Guo Lei,Zhou Yong
We report on a giant magnetoresistance (GMR) based immunosensor for the carcinoembryonic antigen (CEA) labeled with superparamagnetic microparticles (Dynabeads). The GMR sensor contains 200 GMR strips and was fabricated by micro-electromechanical system (MEMS) technology. This system can detect Dynabeads in concentrations down to 10 ng⋅mL −1 . Sandwich immunoassays were employed on the surface of a gold film modified with a self-assembled monolayer and using biotinylated secondary antibody against CEA and streptavidinylated Dynabeads. With DC magnetic fields in the range of 40 to 90 Oe, CEA can be detected with a detection limit as low as 10 pg⋅mL −1 . Samples spiked with different concentrations of CEA can be distinguished clearly, and the method is deemed to be well suited for clinical use.
Make use of antigen-antibody immune reaction, Dynabeads that conjugated with polyclonal CEA antibodies were captured onto the surface of Au film which immobilize of monoclonal CEA antibodies. Under the dc magnetic field magnetizing, the superparamagnetism Dynabeads induced a weak magnetic field that can be detected by the nearby GMR sensor, which reveals the presence of CEA. GMR: giant magneto-resistance CEA: carcinoembryonic antigens.
研究领域:
生物传感器
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生物医学工程
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分子诊断
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癌症研究
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产品关联
DOI
高影响因子
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
·
2022
·Vol. 32
·期 6
·065009
·
IF 2.282
Minjie Zhu,Rui Liu,Hongbo Sang,Xiaohui Du,Shuai Liu,Xinyu Liu,Kemeng Ji,Yanwei Xiong,Xiaojuan Li,Yifang Liu,Lingyun Wang
This paper reports a method for the preparation of glass by reflowing commercial mixed micro and nano powders. High-quality micro-structure glass is formed by a microfabrication process combined with reflow process of the mixed micro and nano powders. The quality of glass prepared by different components was investigated and analyzed. Characterization of the formed glass micro-structure was performed by combining scanning electrical microscopy, energy dispersive spectroscopy, x-ray diffraction, and x-ray photoelectron spectroscopy. The glass reflow results were compared with the anodic bonding sample, which showed micro-structure glass prepared by our method was well-formed with high density and transparency. These results may inspire new possibilities for glass-based microsystems and MEMS applications.
研究领域:
材料科学
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微制造技术
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纳米技术
·
光学
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DOI
高影响因子
CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Chenchen Zhou,Jia Man,Jianyong Li,Bin Qi,Zesheng Hua,Chenxu Liu,Minyi Zhang,Jianfeng Li
Anisotropic ceramic microparticles have been extensively studied in various fields such as mechanical transmission, wave absorbing, structural materials, and abrasives owing to their remarkable properties. The shape of the microparticles plays an important role in their functions. Here, we presented a facile and tunable microfluidic approach to fabricate the ceramic microparticles (∼370 μm in diameter) with the bowl shape, which have been quite challenging for synthesizing to date. Double UV lights were applied to shape the microparticles. By tailoring the cross angle and the intensities of both UV lights, bowl-shaped ceramic microparticles with different opening sizes (0–340 μm) and hollow spherical ceramic microparticles with different-sized through-holes ( f = 0–0.265) were fabricated. These obtained ceramic microparticles hold great potentials to be used as the micro-components in sewage filters, micro ball valves, MEMS , micro-robots, and so forth.
研究领域:
材料科学
·
微流控技术
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纳米技术
·
机械工程
·
环境工程
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产品关联
DOI
高影响因子
Advanced Science
·
2023
·
IF 15.1
Yi-Wei Hu,Yu-Heng Wang,Fang Yang,Ding-Xin Liu,Guang-Hao Lu,Sheng-Tao Li,Zhi-Xiang Wei,Xiang Shen,Zhuang-De Jiang,Yi-Fan Zhao,Qian Pang,Bai-Yang Song,Ze-Wen Shi,Shareen Shafique,Kun Zhou,Xiao-Lian Chen,Wen-Ming Su,Jia-Wen Jian,Ke-Qi Tang,Tie-Long Liu,Ya-Bin Zhu
Electrical stimulation (ES) is proposed as a therapeutic solution for managing chronic wounds. However, its widespread clinical adoption is limited by the requirement of additional extracorporeal devices to power ES-based wound dressings. In this study, a novel sandwich-structured photovoltaic microcurrent hydrogel dressing (PMH dressing) is designed for treating diabetic wounds. This innovative dressing comprises flexible organic photovoltaic (OPV) cells, a flexible micro–electro–mechanical systems (MEMS) electrode, and a multifunctional hydrogel serving as an electrode–tissue interface. The PMH dressing is engineered to administer ES, mimicking the physiological injury current occurring naturally in wounds when exposed to light; thus, facilitating wound healing. In vitro experiments are performed to validate the PMH dressing's exceptional biocompatibility and robust antibacterial properties. In vivo experiments and proteomic analysis reveal that the proposed PMH dressing significantly accelerates the healing of infected diabetic wounds by enhancing extracellular matrix regeneration, eliminating bacteria, regulating inflammatory responses, and modulating vascular functions. Therefore, the PMH dressing is a potent, versatile, and effective solution for diabetic wound care, paving the way for advancements in wireless ES wound dressings.
研究领域:
生物医学工程
·
伤口愈合
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糖尿病
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电刺激
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光伏技术
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生物电子学
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组织工程
·
感染控制
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产品关联
DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Dongze Lv,Ziwen Tang,Yingzhi Wang,Jiaquan Xu,YeJia Wu,Guoqiang Wu,Jin Xie
3D hand reconstruction is an advanced technology in human-machine interaction (HMI), robotic control, and medical rehabilitation applications. However, methods based on optical cameras and data gloves suffer from high equipment costs, complex algorithms, susceptibility to ambient light interference, and high drift of inertial measurement units (IMUs). Here, a soft electronic skin (E-skin) for 3D hand reconstruction, inspired by human biology is proposed, which integrates a multi-sensor fusion of stretchable carbon nanotubes (CNTs) strain sensors and microelectromechanical system (MEMS) ultrasonic transducers. A straightforward screen-printing process is introduced- to fabricate a multi-layer stacked structure of the E-skin. The substrates of both the E-skin and strain sensors use the same material, a polyethylene glycol (PEG) mixed polydimethylsiloxane (PDMS) adhesive (PPA), which strengthens the bonding between the layers. The optimized PPA exhibits a low modulus (186 kPa), high elongation (>220%), and strong adhesion (1.2 N cm −1 ), while the PPA-CNT composite strain sensor demonstrates excellent sensitivity linearity (0.99) and minimal resistance drift over 500 stretching cycles. The PPA material combines the waterproof and biocompatible properties of PDMS, while also achieving high adhesion and softness, allowing it to maintain conformal contact during finger bending (strain >70%) without glue or bandage. A Quantile Regression Neural Network (QRNN) algorithm is introduced to improve dynamic accuracy and robustness in finger joint angle detection. The system's application in gesture recognition and VR interaction is demonstrated, achieving high accuracy in sign language recognition and robust hand tracking.
研究领域:
生物医学工程
·
柔性电子学
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人机交互
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机器人技术
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传感技术
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人工智能
·
虚拟现实
·
信号处理
·
材料科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2016
·
IF 3.014
Haibo Li,Pengcheng Zhang,Gan Li,Junbo Lu,Quanwen Wu,Yuejiao Gu
Stress as an important parameter of thin films can seriously affect on the properties, performance and long-term stability of the films. Here, we propose a semiquantitative method based on Raman spectroscopy for the stress measurement on nonstoichiometric ceria oxide films . The “chemical strain” of lattice caused by oxygen deficits was a main obstacle factor for the stress measurement of CeO 2−δ films, which was overcome through the calibration of lattice vibration peaks by the normalized intensity of Ce 3+ ions in Raman spectra . A compressive stress about −1.38 ∼ −1.50 GPa was obtained on an oxidated Ce film, which was verified by the substrate-curvature method. Based on the proposed method, Raman spectroscopy could be expanded to wider application fields as an in-situ stress measurement tool, such as in the fields of oxygen-ion-conducting solid electrolytes , oxidation film of alloys, microelectronics and MEMS devices, etc.
研究领域:
材料科学
·
固态离子学
·
薄膜物理
·
微纳电子器件
·
MEMS
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DOI
高影响因子
危险品化学品经营许可证（带存储）