FOOD AND CHEMICAL TOXICOLOGY
·
2022
·
IF 5.572
Shanshan Hu,Zhiyuan Lin,Sibo Zhao,Bowen Zhang,Liyong Luo,Liang Zeng
Brain inflammation develops with increased colitis . Pu-erh tea is considered a potential dietary intervention to improve colitis. However, it's unclear whether Pu-erh tea helps alleviate colitis-mediated brain dysfunction . Here, we found that colitis triggered brain dysfunction and increased the risk of depression. Pu-erh tea improved gut-brain barrier function (increased ZO-1 and Occludin) and restored short-chain fatty acids (SCFAs) as well as neurotransmitter release (γ-GABA, 5-HT, and dopamine), which stemmed from the production of butyric acid (BA). Pu-erh tea and BA promoted the production of SCFAs by reshaping the gut microbes (increased Lactobacillus , Akkermansia , Faecalibaculum ), thereby downregulating gut inflammatory protein expression (PI3K/AKT/NF-κB). SCFAs, especially BA, intervened directly in the blood-brain barrier via the gut-brain axis to restore neurotransmitter release. Collectively, our results highlighted that increasing BA through Pu-erh tea consumption may be a key mechanism for improving colitis-mediated brain dysfunction by lowering gut inflammation and balancing gut microbe-gut-brain axis homeostasis . These results provide a promising step that might encourage further investigations of Pu-erh tea as a protective agent for brain function in colitis patients.
研究领域:
胃肠病学
·
神经科学
·
微生物学
·
营养科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2021
·
IF 4.464
Ya Liu,Wenzhu Tang,Gaowei Zhang,Wenhao Chen,Qingze Chen,Chunlin Xiao,Shenghui Xie,Yejun Qiu
Developing stable and efficient electrocatalysts for hydrogen evolution reaction is of great significance for the production of clean hydrogen energy from water splitting. In this work, 3D AgNWs@NiMo/PU electrode was obtained by electrodepositing NiMo alloy onto three-dimensional silver nanowires conductive substrate (3D AgNWs/PU) which was uniformly assembled on the surface of the skeleton of a polyurethane sponge (PU). 3D AgNWs/PU provides good electrolyte permeability, rich active site attachment points, good electronic conductivity and electrocatalytic synergy, which greatly improves the catalytic activity. In addition, 3D AgNWs@NiMo/PU electrode does not need to use adhesive in the process of hydrogen evolution, which can improve the hydrogen evolution performance and stability of the electrode. Specifically, the optimized electrode (AgNWs@NiMo/PU-1200 s) exhibits excellent hydrogen evolution performance by achieving a low overpotential of 32 mV (vs. RHE) at a current density of 10 mA cm −2 , with a Tafel slope of 72 mV dec -1 (in 1 M KOH). More interestingly, it also has good stability after 10 h of stability test. Therefore, this study provides a feasible way to develop stable and efficient 3D HER electrocatalysts.
研究领域:
材料科学
·
能源科学
✓ 已验证
产品关联
DOI
高影响因子
Food & Function
·
2023
·Vol. 14
·期 5
·2313-2325
·
IF 6.1
Sibo Zhao,Shanshan Hu,Kang Sun,Liyong Luo,Liang Zeng
Blue light emitted by smartphones and tablets at night increases the risk of depression. Pu-erh tea has been reported to reduce the risk of depression by regulating tryptophan metabolism, but its underlying protective mechanism on depression induced by blue light at night (BLAN) remains unclear. In this work, two groups of C57BL6/J mice were given water or 0.25% (w/v) Pu-erh tea for 120 days, followed by a 45-day BLAN treatment (400 lux blue light between 21:00 and 23:00) to simulate blue light emitted from electronic equipment. Our results indicated that BLAN induced depression-like behaviors and gut microbiota disorders in healthy mice. Pu-erh tea intake significantly reshaped the gut microbiome (especially Bifidobacterium) and regulated the metabolism of short-chain fatty acids (SCFAs) which protected the integrity of the intestinal barrier. This improvement further reduced blood–brain barrier (BBB) damage and alleviated neuroinflammation by inhibiting MyD88/NF-κB pathways which finally regulated neurotransmitters such as brain-derived neurotrophic factor (BDNF) and serotonin (5-hydroxytryptamine, 5-HT). Collectively, 0.25% (w/v) Pu-erh tea has the potential to prevent BLAN-induced depression-like behaviors by reshaping the gut microbiota and increasing the generation of SCFAs via the gut–brain axis.
研究领域:
神经科学
·
药理学
·
微生物学
·
行为科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2023
·
IF 5.9
Chaoying Hu,Jiawei Li,Xianjie Pan,Yanning Zeng
Conventional polyurethane (PU) networks fabricated from nonrenewable fossil resources are difficult to be recycled, reprocessed, and reshaped because of the permanent covalent cross-linked networks, and the flammability of PU networks limits their wide application. Herein, the novel polyols were synthesized from renewable vanillin and then reacted with hexamethylene diisocyanate (HDI) trimer to obtain versatile bio-based PU networks with dynamic disulfide and imine bonds for the first time. Obtain malleable PU networks that possess excellent reprocessability and self-healing performance, as well as superior fire resistance. The vanillin-based PU networks show a high T 5d of ∼180 °C, high char yield of 23% at 800 °C, fast stress relaxation of ∼38 s at 80 °C, excellent scratch self-healing performance with approximately 100% healing efficiency at 120 °C for 90 min, outstanding flame retardancy with high LOI of ∼30% and UL-94 V0 rating. Additionally, the vanillin-based PU networks display excellent malleability with the activation energy ( E a ) of 30.2–54.8 kJ•mol −1 due to dual dynamic bonds in the networks, which can be recycled in 60 min at 120 °C by hot pressing. Moreover, the vanillin-based PU networks with Schiff base can be degraded rapidly in the mixture of HCl and THF. Briefly, produced PU networks from abundant and renewable resources are significant examples to foster the development of versatile PU network materials.
研究领域:
材料科学
·
聚合物化学
·
可持续材料
·
消防安全工程
✓ 已验证
产品关联
DOI
高影响因子
PROGRESS IN ORGANIC COATINGS
·
2024
·
IF 6.5
Biru Shi,Xiaoling Xu,Jiahui Zhong,Zhenyu Zhang,Haosen Ma,Yu He,Xinxin Tian,Yan Zhou,Xiangdong Liu,Dekun Sheng,Yuming Yang
Hot-melt adhesive (HMA) is commonly used in industrial manufacturing due to its ease of use. However, the direct factors that affect shear strength have been unclear in recent years, making it difficult to prepare hot melt adhesives with high shear strength, which are mostly lower than 6 MPa. In this study, three types of polyurethane HMAs, differing in the position of H-bond motifs, ureidopyrimidinone (UPy), were synthesized and characterized, the most central factor for shear strength, Young's modulus , was firstly found out and proved. Side-chain UPy provides better flexibility and more chain entanglement . The lap shear strength of SPU was about 13.48 MPa, which was the highest shear strength of PU HMA, and remained 73.4 % even after 4 cycles. Compared to the other two samples, the side-chain motifs improved the possibility of forming hydrogen bonds with adherends and increased chain mobility. This led to a more efficient wetting process and strengthened Young's modulus directly, enhancing adhesive property incomparably. This work provides a satisfactory method for achieving high shear strength in HMA.
研究领域:
材料科学
·
化学工程
·
聚合物科学
✓ 已验证
产品关联
DOI
高影响因子
CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2020
·
IF 2.627
Guohao Du,Jianfeng Hu,Jianhui Zhou,Guangwu Wang,Shengli Guan,Hailing Liu,Man Geng,Chuang Lü,Yaoqiang Ming,Jinqing Qu
The self-healing microcapsules can be buried in the coating to improve the anticorrosive ability. In this paper, self-healing microcapsules of polyurea (PU)/melamine resin (MF) double shell were prepared by in-situ polymerization and interfacial polymerization with isocyanate as the core material. Scanning electron microscope was used to observe the microcapsule morphology. The structures of microcapsules prepared with different chain extenders were characterized by Fourier transform infrared spectroscopy . The micromanipulation system was used to loading–holding, loading–unloading and loading to rupture individual microcapsules, so as to explore the mechanical properties of microcapsules. The Young's modulus corresponding to microcapsules was calculated by mathematical model fitting. The self-healing properties of microcapsule coating were characterized by optical microscope . The experimental results showed that the microcapsule shell prepared under optimized conditions had a complete morphology and good mechanical properties . The microcapsule was in the elastic deformation stage under small deformation , and the plastic deformation stage under large deformation . The Young's modulus range of microcapsules was 9.29–14.51 MPa, and the corresponding Young's modulus could be prepared by adjusting the process. The surface crack of the coating containing microcapsule could heal itself after 48 h in a humid environment .
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
EUROPEAN POLYMER JOURNAL
·
2024
·
IF 5.8
Huangying Guo,Haonan Zhang,Wenyao Li,Rijia Jiang,Xiaolong Liang,Xing Zhou
With the rapid development of today’s society, magnetic self-healing materials are widely used in many fields due to their excellent magnetism and self-healing ability. This article presents a magnetic self-healing composite with good mechanical, self-healing and magnetic properties and magnetic drive performance. Tetraethyl orthosilicate (TEOS), silane coupling agent and succinic anhydride (SA) were used for surface modification of NdFeB magnetic particles (MPs) and NdFeB@SiO 2 -COOH MPs was synthesized. Iron(III) ions were added to the self-polymerization process of the natural small molecule thioctic acid (TA) to form the PTA-Fe prepolymer. PTA-Fe prepolymer, isophorone diisocyanate (IPDI) and polyether amine (PEA) reacted to synthesis PTA-Fe-PU matrix with good self-healing performance at room temperature. The prepared NdFeB@SiO 2 -COOH MPs was mixed with the self-healing matrix and cured to obtain the magnetic room-temperature self-healing composite MPTA-Fe-PU. The best tensile strength of the composite was 7.31 MPa and the ultimate elongation was 833 %. After the prepared MPTA-Fe-PU sample strip was completely cut, the incision on the surface almost disapeared and the tensile strength recovered to 6.35 MPa after 12 h self-healing at room temperature. The self-healing efficiency was up to 87 %. The highly efficient self-healing properties were mainly derived from the disulfide bonds exchange reaction and iron(III) ion coordination in the matrix.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Journal of Coatings Technology and Research
·
2024
·
IF 2.3
Huang Zhichao,Wang Lin,Wu Hongfu,Zhang Junfeng,Wang Zhuo,Sun Fu,Duan Huimin,Qi Dongming
Herein, a simple and efficient inorganic particle surface modification strategy was developed to improve the flame retardancy of flammable polyurethane (PU) materials while avoiding the serious degradation of their mechanical properties due to the incorporation of inorganic particles. Novel organic–inorganic hybrid hydroxylation ammonium polyphosphate (OHAPP) was fabricated via an ion-exchange reaction between APP and diethanolamine, and a PU/OHAPP film was prepared by crosslinking OHAPP with reactive PU via in situ polymerization. The curing properties, flame retardancy, and mechanical properties of materials were evaluated. Results showed that the addition of 15 wt% OHAPP in PU increased the tensile strength of the sample by 16% compared to PU alone. The peak heat release rate, total heat released, and total smoke produced from the materials measured via the conical calorimetric method were 337.2 kW/m 2 , 78.1 MJ/m 2 , and 8.9 m 2 , respectively, which were 63.8%, 43.6%, and 15.2% lower than those of PU. Additionally, the flame-retardant mode of action of the PU/OHAPP film was verified. This study is a useful reference for further studies on flame-retardant materials.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Advanced Science
·
2026
·
IF 14.1
Yifan Wang,Yanjun Lv,Qilong Tang,Huaixin Hao,Jianfeng Jia,Gang Ye,Jing Chen,Chao Xu,Zhipeng Wang
Addressing the challenges of nuclear waste management and strategic resource recovery necessitates novel functional materials for the integrated and efficient capture of critical elements. This work reports a class of multifunctional eutectic mixtures (EMs) constructed from crown ether (hydrogen-bond acceptor, HBA) and partially esterified organophosphorus acids (hydrogen-bond donor, HBD). This design integrates the high selectivity of crown ether toward Sr(II) with the strong affinity of organophosphorus ligands for U(VI)/Pu(IV), achieving unprecedented single-step extraction efficiencies exceeding 99.9% for U(VI), 99.8% for Pu(IV), and 99% for Sr(II) under extreme and nearly realistic conditions. This exceptional performance originates from the differentiated metal coordination of crown ether and phosphoric esters, coupled with a synergistic “coordination-encapsulation” effect mediated by the formation of reverse micellar supramolecular structures. Our findings not only provide high-performance materials for the simultaneous recovery of critical radionuclides but also demonstrate the great potential of EMs as a sustainable platform for addressing complex separation scenarios.
✓ 已验证
DOI
PubMed
高影响因子
Separations
·
2025
·Vol. 12
·期 5
·106
·
IF 2.7
Xiaoyun Guo,Junli Wang,Yao Liu,Haojun Zhao,Hui Wang,Wentao Wang,Baole Li,Taihong Yan
Developing a new efficient separation ligand based on the “CHON” principle to address the limitations of phosphorus containing extractants in nuclear fuel reprocessing can help further simplify the process flow and reduce the amount of secondary waste. Building upon this critical need, a novel ligand was developed through a strategic application of the Hard and Soft Acids and Bases (HSAB) theory, integrating a soft donor nitrogen atom into the linear architecture of bis-diglycolamide. This groundbreaking ligand, named N,N′-bis[2-(2-(N,N-dioctylcarbamoyl)ethoxy)ethylacetamido]-N″-diethylenetriamine (TOMDEA-BisDGA), has demonstrated remarkable potential in the extraction of Pu(IV). The study unveils that the ligand demonstrates remarkable selectivity and separation efficiency towards Pu(IV) ions while maintaining an exceptionally low extraction capacity for U(VI) across a wide acidity spectrum of 0.1~6 mol/L. To explain the structure properties of complex formed by the ligand and Pu(IV), a systematic analysis was performed, including slope analysis, proton nuclear magnetic resonance (NMR) titration, and Fourier-transform infrared (FT-IR) spectroscopy. This study explores the coordination and separation behavior of diglycolamide ligands with actinide. This work is expected to provide important information and theoretical bases upon which advanced design and optimization of ligands for high-performance processes for the separation of plutonium might be carried out. Such findings will contribute to the understanding of actinide chemistry and further the design of improved separation methods for nuclear applications.
研究领域:
核化学
·
配体设计
·
放射化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Linjie Wei,Xiubin Xu,Hongchun Mu,Wantong Lin,Jiahui Tang,Jieran Li,Jianwei Liu,Haitao Dong,Danfeng Yu,Xu Wu
Current fluorescent polyurethanes face critical challenges, including cytotoxic fluorescent labels, irreversible damage from mechanical stress, and monofunctional behavior lacking stimulus-responsive sensing capability. To address these limitations, we developed a polyurethane elastomer that merges extreme stretchability, autonomous self-healing, and circular recyclability. Engineered via adipic dihydrazide and 4, 4′-diaminodiphenyl disulfides, the network unites reversible disulfide metathesis with hydrogen-bond dissipation, yielding 10 MPa strength, 3200 % elongation, and 90 % toughness recovery within 72 h. Notch tolerance reaches 1200 % strain, while 75 % ethanol depolymerisation at 25 °C enables solvent-cast recycling (>80 % retention in tensile strength). The matrix confines curcumin, suppressing aggregation-caused quenching and furnishing stable solid-state fluorescence under water for 14 days. Emission color switches from green to yellow in response to substrate polarity. Applications include stamp-sealable anti-counterfeiting inks and real-time pork-freshness sensors that visually report spoilage through pH-triggered fluorescence decay. This work overcomes key limitations in natural fluorophore applications by establishing a structure-property optimization paradigm that simultaneously achieves high performance, environmental sustainability, and multifunctionality for safety-sensitive applications.
✓ 已验证
产品关联
DOI
高影响因子
ACS Omega
·
2026
·
IF 5.2
Shuo Zhang,Zhao Wang,Tao Xie,Zhihao Feng,Xiaowei Huang,Xin Ning,Jinfa Ming
To date, it has been challenging for electromagnetic interference (EMI) shielding materials undergoing external mechanical stimuli containing stretching, bending, or large deformations to maintain excellent EMI shielding effectiveness and long-term structural stability. At the same time, EMI shielding materials require high shielding effectiveness and low reflection, reducing secondary pollution of electromagnetic waves. Herein, porous core–shell polyurethane (PU) fibers featuring a rich porous microstructure are prepared by coaxial wet spinning, with elastic elongation capacity exceeding 1500%. This work explores a porous core–shell PU fiber substrate by loading silver nanowires (AgNWs), forming an interconnected conductive network in the PU fiber matrix. The resultant composite is stable, successfully achieved through the thermal adhesion of PU nanofibers between the AgNW functional layer and the PU substrate layer. The composite (500 mg of PU fiber substrate) loading of 36 mg of AgNWs results in the EMI shielding efficiency of 39.41 dB. While it is stretched under 10% deformation, its EMI shielding efficiency exceeds 23.14 dB. Even if electromagnetic waves are randomly incident from both sides of the composite, it maintains excellent EMI shielding performance. In summary, this type of composite with excellent EMI shielding performance can be used in applications where flexibility, lightweight, and bendable conditions are the primary requirements.
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）