SEPARATION AND PURIFICATION TECHNOLOGY
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2026
·
IF 9.1
Rongpeng Yu,Qinya Huang,Wanyi Wang,Liangyin Xiang,Shakeel Zeb,Zhanchao Liu,Zheng Chuanbo,Yan Liu
This study explores the synthesis and application of a 2D block -shaped covalent organic framework(COF) and its integration into a surface molecularly imprinted polymers(SMIPs) for the selective adsorption of Myricetin(Myr) from food samples. The COF was synthesized using a binary deep eutectic solvent(DES1) composed of choline chloride and glycerol, while the molecularly imprinted polymers(MIPs) were polymerized on the surface of the COF utilizing a ternary deep eutectic solvent(DES2), consisting of choline chloride, acrylamide, and ethylene glycol. After optimizing the proportion of DESs, the resulting 50%-DES applied to COF(DC)-MIP exhibited a high adsorption capacity of 40.04 mg/g within 0.5 h at pH 6.0. The adsorption process, characterized by Langmuir isotherms and pseudo-second-order kinetics, was exothermic. The XPS and UV–Vis spectra confirm the adsorption mechanisms, indicating that Myr adsorption onto the COF-based MIP was predominantly driven by hydrogen bonding and π-π stacking interactions. Due to the COF serving as the matrix material, which enhances the structural stability and solvent resistance of the polymer, the 50%-DC-MIP demonstrated excellent recyclability, maintaining consistent performance over five cycles. Because of excellent selectivity, the 50%-DC-MIP was effectively employed to grape juice, bayberry juice and green tea resulting in satisfactory recoveries of 94.67% to 102.25%, 93.75% to 108.33% and 97.33% to 101.15%, respectively. These findings highlight the potential of COF-based MIPs for the selective extraction and detection of bioactive compounds like Myricetin in complex food samples, aligning with green chemistry principles by utilizing DES as environmentally friendly solvents.
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高影响因子
Chinese Journal of Chromatography
·
2023
·Vol. 41
·期 2
·187-194
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IF 0.7
Liu H,Li Y,Zi M,Chen Z,Duan A,Yuan L.
Covalent organic frameworks （COFs） are an emerging class of porous crystalline materials composed of multidentate organic units connected by covalent bonds. COFs have been demonstrated to exhibit great potential and research value in many fields， including gas storage and separation， photoelectric devices， fluorescence sensors， catalysis， drug delivery， dye and pollutant adsorption， and electronic devices， and so on. The COFs obtained by post-synthesis modification tend to exhibit high crystallinities and porosities， thereby rendering them suitable materials for use in the fields of chiral resolution， asymmetric catalysis， and chromatography. In this work， TpPa-NO 2 was synthesized from 1，3，5-tricarbaldehyde phloroglucinol and 2-nitro-1，4-phenylenediamine， which was then reduced to TpPa-NH 2 . Subsequently， this material was modified with D-glucose via a post-synthesis modification strategy to obtain the TpPa-NH 2 -Glu. TpPa-NH 2 -Glu were characterized by nuclear magnetic resonance （NMR） spectroscopy， Fourier transform-infrared （FT-IR） spectroscopy， X-ray powder diffraction （XRD） analysis， etc. In the XRD pattern， the peaks observed at 4.7°， 8.1°， 11.1°， and 27° were attributed to the TpPa-NH 2 -Glu， and these peaks are consistent with previous reports， thereby confirming the successful synthesis of this derivative. In addition， circular dichroism experiments indicated that the TpPa-NH 2 -Glu exhibited a Cotton effect， further confirming the chiral COF was prepared. Subsequently， this material was immobilized on the surface of spherical silica gel particles via the net-wrapping method to prepare a stationary phase for high performance liquid chromatographic column. Using n -hexane-isopropanol （9∶1， v/v） or methanol-water （9∶1， v/v） as mobile phases at a flow rate of 0.5 mL/min， 16 racemates and two benzene-based positional isomers （ o ， m ， p -nitroaniline and o ， m ， p -Iodoaniline） were successfully resolved by this chiral column. In addition， under methanol-water （9∶1， v/v） mobile phase conditions， five racemates were separated， among which propranolol hydrochloride， warfarin， and metoprolol reached baseline separation. Furthermore， under n -hexane-isopropanol （9∶1， v/v） mobile phase conditions， 11 racemates were resolved， among which ethyl 2-bromopropionate and 3-butyn-2-ol reached baseline separation. Meanwhile， the effect of temperature on the TpPa-NH 2 -Glu liquid chromatography column and the repeatability of the TpPa-NH 2 -Glu liquid chromatography column were also explored. The HPLC column prepared by TpPa-NH 2 -Glu had good repeatability， and its relative standard deviation （RSD） was 1.55% and 1.46%， respectively. It is demonstrated that the TpPa-NH 2 -Glu material has good resolution ability for chiral compounds.
研究领域:
分析化学
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材料科学
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色谱学
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有机化学
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分离科学
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PubMed
高影响因子
Food Analytical Methods
·
2022
·Vol. 16
·期 1
·71-82
·
IF 3.498
Wang Qingying,Chen Lianfang,Li Yongli,Yang Jing,Yang Rui,Yang Xiupei
In this work, a magnetic covalent organic framework (COF) named Fe 3 O 4 @TpPa-NO 2 was designed and synthesized by a solvothermal method employing 1,3,5-triformylphloroglucinol (Tp) and 2-nitro-p-phenylenediamine (Pa-NO 2 ) as the organic units. Fe 3 O 4 @TpPa-NO 2 was explored as an adsorbent for magnetic solid-phase extraction (MSPE) of four pyrethroid insecticides. Fe 3 O 4 @TpPa-NO 2 displayed excellent adsorption capacity in the adsorption test of pyrethroid insecticides. Taking bifenthrin as an example, the adsorption capacity reached 885 mg·g −1 . A sensitive method for the determination of pyrethroid pesticide residues was developed using high-performance liquid chromatography (HPLC) coupled with MSPE. The linearity of the proposed method has a correlation coefficient ( R 2 ) of 0.9992–0.9999 in the range of 15–1000 ng·mL −1 . Under optimal conditions, the limits of detection (LODs) and limits of quantification (LOQs) were 3.98–6.21 and 13.28–22.05 ng·mL −1 , respectively. Furthermore, satisfactory precision and accuracy were obtained with relative standard deviations (RSDs) of 2.58–3.42% and recoveries of 85.7–109.8%. The adsorption mechanism inferred that π-π interactions, hydrophobic interactions, and hydrogen bonding could promote the adsorption of pyrethroids. The developed MSPE-HPLC method has the advantages of rapidity, accuracy, sensitivity, recyclability, and good practical applicability.
研究领域:
分析化学
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环境科学
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食品科学
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高影响因子
Journal of Materials Chemistry B
·
2017
·Vol. 5
·期 22
·4052-4059
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IF 4.543
Heping Wang,Fenglong Jiao,Fangyuan Gao,Junjie Huang,Yan Zhao,Yehua Shen,Yangjun Zhang,Xiaohong Qian
Protein glycosylations play important roles in various biological processes and in the disease progression of organisms. The development of specific enrichment materials and strategies before mass spectrometric analysis was a prerequisite to glycoproteomic analysis due to the difficulty caused by substoichiometric levels of glycoproteins. In this work, novel magnetic covalent organic frameworks (denoted as Fe3O4@TpPa-1) were first developed using only a two-step solvothermal reaction and then applied in the hydrophilic enrichment of glycopeptides. Sea urchin-type composites with super-paramagnetic properties were constructed by in situ growth of TpPa-1 covalent organic frameworks on the surface of magnetic nanoparticles. A total of 37 and 22 glycopeptides could be easily detected from IgG and HRP digests, respectively, by hydrophilic enrichment with the newly developed materials. An ultralow detection limit (28 fmol), satisfactory selectivity and high recovery could be achieved using Fe3O4@TpPa-1. The material's excellent enrichment performance was also demonstrated using glycopeptide analysis in real complex samples. Within three independent replicates, 228 glycopeptides corresponding to 114 glycoproteins could be detected from human serum digests, which is better than the performance obtained by commercial HILIC materials. The results suggest that covalent organic frameworks show potential for application in glycoproteomic studies.
研究领域:
分析化学
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生物化学
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材料科学
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PubMed
高影响因子
JOURNAL OF SEPARATION SCIENCE
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2022
·Vol. 45
·期 9
·1493-1501
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IF 3.614
Chengjiang Zhang,Hongmei Yuan,Zeyi Lu,Yuhuang Li,Lirong Zhao,Zhuomin Zhang,Gongke Li
Covalent organic frameworks with tunable porous crystallinity and outstanding stability have exhibited fascinating pretreatment performance as ideal extraction media. Herein, the β-ketoenamine-linked TpPa-1 synthesized by 1,3,5-triformylphloroglucinol and paraphenylenediamine was employed as the absorbent for online micro-solid phase extraction of trace bisphenols combined with high-performance liquid chromatography detection. A series of characterizations indicated that the TpPa-1 possessed large surface areas, high stability, and hydrophobicity. The main experimental parameters affecting the extraction efficiency were optimized in detail. Compared with four commercial sorbents, the TpPa-1 exhibited superior enrichment capacity for extracting bisphenols. Under the optimum conditions, the established method demonstrated a wide linear range and high sensitivity with the limit of detection ranging from 0.05–0.06 μg/L. Furthermore, the developed method was successfully applied to determine bisphenols in plastic samples. Bisphenol A was actually detected in a transparent box with a concentration of 0.31 μg/g, and the recoveries of the four bisphenols in the plastic samples were 80.5–116% with the relative standard deviation less than 9.2%. Such performance was attributed to recognition affinity, including the π-π affinity, hydrophobic effect, and hydrogen bond. These results demonstrated that TpPa-1 possessed great potential to be an excellent pretreatment medium for online separation and analysis of trace analytes in complex samples.
研究领域:
分析化学
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环境科学
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DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Changzhe Zhou,Haojie Li,Longlong Wang,Tao Fu,Guangli Liu,Xiaoran Shen,Huazhang Zhao
Polyester membranes are increasingly utilized in wastewater treatment due to their chlorine resistance. Nonetheless, they face challenges such as limited permeability. The integration of covalent organic frameworks (COFs) can significantly enhance the performance of nanofiltration membranes. However, the heterogeneous dispersion of COFs in solution results in poor compatibility with polyester membranes, leading to increased membrane defects and compromising nanofiltration performance. This study presents the development of COFs-polyester hybrid membranes via a simple one-step in-situ co-polymerization method. During the interfacial polymerization (IP), p-phenylenediamine (Pa) and 1,3,5-triformylphloroglucinol (Tp) were integrated into a β-cyclodextrin (β-CD) aqueous solution and a trimesoyl chloride (TMC) organic solution, respectively. The uniform dispersion of COFs monomers within the IP monomer solution addressed heterogeneity issues, improving compatibility with polyester membranes. The in-situ co-polymerized COFs not only enhanced the sieving capabilities but also improved the hydrophilicity, and free volume of the membranes. The optimized membranes demonstrated a permeance of 105 L/m 2 ·h·bar, with rejection rates of 98.5 % for Congo red and 6 % for Na 2 SO 4 . Moreover, these membranes exhibited remarkable resistance to chlorine, organic solvents, and antifouling capabilities. This study offers novel insights into the application of COFs in polyester membranes, providing a straightforward, cost-effective, and scalable integration strategy.
研究领域:
材料科学
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环境工程
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高影响因子
TALANTA
·
2023
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IF 6.1
Qingying Wang,Lianfang Chen,Xiaoyan Cui,Jie Zhang,Yaohui Wang,Xiupei Yang
Herein, a covalent organic framework (COF) was grown on a magnetic metal-organic framework (MOF) by a solvothermal method for the efficient extraction of bisphenols (BPs). The magnetic solid-phase extraction (MSPE) of four bisphenols (bisphenol A, bisphenol B , bisphenol AF and bisphenol C) was carried out without adjusting the pH and salt concentration. When 30 mg Fe 3 O 4 @NH 2 -MIL-88(Fe)@TpPa was used to adsorb for 25 min, 6 mL methanol was used to elute for 20 min, and the extract was detected by high-performance liquid chromatography (HPLC). The proposed method has a low detection limit of 0.011–0.036 ng mL −1 , a wide linear range of 0.05–100 ng mL −1 , and a correlation coefficient (R 2 ) of 0.9980–0.9998. The intra-day and inter-day precisions are 0.74–2.54% and 1.68–3.72%, respectively. Bisphenol A was determined by applying the proposed method to the determination of actual milk samples. The standard addition experiment showed that the relative recovery of the four bisphenols was 85.70–119.7%. Pseudosecond-order, first-order, Langmuir and Freundlich models were applied to explore the adsorption characteristics of Fe 3 O 4 @NH 2 -MIL-88(Fe)@TpPa. In general, the established Fe 3 O 4 @NH 2 -MIL-88(Fe)@TpPa-MSPE-HPLC-UV method exhibits attractive sensitivity, simple manipulation, and excellent reusability, and it has excellent prospects for the detection of trace BPs in complex milk matrices.
研究领域:
分析化学
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环境科学
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食品科学
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PubMed
高影响因子
APPLIED SURFACE SCIENCE
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2022
·
IF 7.392
Mei-Ling Xu,Jia-Ran Li,Xiu-Mei Wu,Ting Yu,Guan-Ying Qin,Fu-Ji Wang,Li-Na Zhang,Kui Li,Xin Cheng
Covalent organic frameworks (COFs) as an emerging porous material have exhibited excellent application prospects in the field of photocatalysis. Nevertheless, the overall water splitting using solar energy by COF-based photocatalysts remains a huge challenge due to the rapid charge recombination and insufficient redox catalytic capacity. Herein, for the first time, the novel Fe-MOF-derived α-Fe 2 O 3 and FeP-PC was designed and adopted as dual co-catalysts to facilitate the separation and utilization efficiency of charge carriers and activate the overall water splitting performance of the ketoenamine based TpPa-1-COF, with both the porous α-Fe 2 O 3 and FeP-PC acting as the framework supporting to effectively prevent the agglomeration of TpPa-1-COF during the fabrication and photocatalytic process. Meanwhile, the construction of Z-scheme heterostructures and the connection of covalent bonds in the interface of α-Fe 2 O 3 /TpPa-1-COF/FeP-PC effectively facilitate the separation and transport of charge. Consequently, the optimal α-Fe 2 O 3 /TpPa-1-COF/FeP-PC excites very competitive photocatalytic overall water splitting performance.
研究领域:
材料科学
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光催化技术
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能源转换
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高影响因子
Journal of Inorganic and Organometallic Polymers and Materials
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2023
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IF 4
Zhang Xue-Feng,Chang Tian-Long,Guo Na,Jia Guo-Liang,Li Xiao-Bing,Zhao Zhao-Ye,Wang Hui,Wang Jun-Chuan,Wu Xiang-Feng,Pan Cheng-Si,Liu Lei,Yang Lin-Lin
Fe-based MOFs (Fe-MOFs) are excellent photocatalysts and have synergy well with Fenton reagents relative to other MOFs. In this work, a series of uniformly covered NH 2 -Fe-MIL-88B@TpPa-1-COF composites were synthesized using an in-situ anchoring growth strategy, which used F127 as functional molecule to decorate NH 2 -Fe-MIL-88B nanoparticles to eliminate their surface electrostatic repulsion with Tp molecules during the subsequent coating procedure. Meanwhile, the -NH 2 groups in the skeleton of NH 2 -Fe-MIL-88B could also be used as anchors to covalently connect TpPa-1-COF shell and migration channels for effective charge transfer. This uniformly covered core–shell structure would endow these composites with much more contact area and imine bond linkage between the Fe-MOFs core and COFs shell. Compared with the random packing structure, the uniformly covered Fe-MOF@COF-3 composite possessed a higher proportion of Fe 2+ to Fe 3+ . As a result, the optimized Fe-MOF@COF-3 catalyst could achieve the highest photo-Fenton degradation efficiency of 93.9% for tetracycline hydrochloride (TC⋅HCl), which was much higher than 54.8% of pure NH 2 -Fe-MIL-88B. In addition, the uniform TpPa-1-COF shell could further effectively enhance the stability of NH 2 -Fe-MIL-88B by protecting Fe ions from leaching, and the toxicity of the water samples treated with our photo-Fenton degradation process declined obviously. All these merits will endow Fe-MOF@COF-3 photo-Fenton catalyst great potential application value as in the field of environmental governance.
研究领域:
材料科学
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环境科学
·
催化
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Fusheng Pan,Weixiong Guo,Yanlei Su,Niaz Ali Khan,Hao Yang,Zhongyi Jiang
Covalent organic frameworks (COFs) are emerging as crystalline porous materials for advanced membranes, due to their regular pore structures and high porosity. The fabrication of defect-free ultrathin COFs membranes is still very challenging, since the poor COF-substrate affinity hampers the nucleation of COF crystallites. In this work, a facile direct growth method was developed to deposit continuous imine-based COF layer (TpPa-1, synthesized by the Schiff-base reactions of 1,3,5-triformylphloroglucinol (Tp) with p-phenylenediamine (Pa-1)). Aldehydes groups were firstly immobilized on polyacrylonitrile (PAN) porous substrate as the nucleation sites to promote the growth of continuous TpPa-1 layer via a good COF-to-substrate adhesion. Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM) and X-ray diffractometer (XRD) confirmed the formation of COF layer. The TpPa-1/HPAN membrane exhibited high water flux of 418.5 L/(m 2 h MPa) under the operation pressure of 0.1 MPa and excellent dyes rejection (93.91% for Orange GII and over 99% for Methyl blue, Congo red and Alcian blue). The high separation performance, coupled with its facile fabrication and remarkable stability, may render imine-based COFs membrane promising for wastewater treatment.
研究领域:
材料科学
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环境工程
·
化学工程
·
膜技术
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高影响因子
Small
·
2022
·Vol. 18
·期 25
·2201340
·
IF 15.153
Ge Yan,Xiaodong Sun,Kailai Zhang,Yu Zhang,Hui Li,Yuhai Dou,Ding Yuan,Hongwei Huang,Baohua Jia,Hao Li,Tianyi Ma
2D covalent organic frameworks (COFs) are considered as one kind of the most promising crystalline porous materials for solar-driven hydrogen production. However, adding noble metal co-catalysts into the COFs-based photocatalytic system is always indispensable. Herein, through a simple solvothermal synthesis method, TpPa-1-COF, a typical 2D COF, which displays a wide light absorption region, is rationally combined with transition metal phosphides (TMPs) to fabricate three TMPs/TpPa-1-COF hybrid materials, named Ni 12 P 5 (Ni 2 P or CoP)/TpPa-1-COF. The incorporated TMPs can be served as electron collectors for accelerating the transfer of charges on TpPa-1-COF, thus the composites are demonstrated to be efficient photocatalysts for promoting water splitting. Benefitting from the richer surface reactive sites and lower H* formation energy barrier, the Ni 12 P 5 can most effectively improve the photocatalytic performance of the TpPa-1-COF, and the H 2 evolution rate can reach up to 31.6 µmol h −1 , approximately 19 times greater than pristine TpPa-1-COF (1.65 µmol h −1 ), and is comparable to the Pt/TpPa-1-COF (38.8 µmol h −1 ). This work is the first example of combining COFs with TMPs to construct efficient photocatalysts, which may offer new insight for constructing noble-metal-free COF-based photocatalysts.
研究领域:
材料科学
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化学
·
能源科学
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催化
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DOI
PubMed
高影响因子
ACS Applied Polymer Materials
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2023
·
IF 5
Zhipeng Zhao,Huimeng Feng,Dong Qin,Wen Li,Wei Wang,Shougang Chen
Herein, we designed and synthesized a two-dimensional covalent organic framework (2D-COF) of a Schiff base using a mechanical chemical grinding method. Moreover, capsaicin@chitosan (CAP@CS) microcapsules were loaded on a TpPa-1 COF by a physical adsorption method to prepare composites (CAP@CS/TpPa-1), which realized the pH-sensitive controlled release of the fungicide CAP, dispersed in fluorocarbon resin to prepare an intelligent coating with environmentally friendly long-term antifouling performance. TpPa-1 improves the antibacterial efficiency by increasing the dispersity of CAP@CS in the resin. Therefore, a CAP release amount of 2 wt % composite coating can meet the minimum bacteriostatic concentration of 37.5 μg/mL required for antifouling. Importantly, pH-responsive controlled release caused by the protonation of CS and the electrostatic interaction between CAP@CS and TpPa-1 COF and increased bacterial contact area by CAP@CS reunion inhibited by TpPa-1 COF improve the bactericidal efficiency of the composite. The composite coating has excellent corrosion resistance, mainly because COF extends the propagation path of the corrosive medium.
研究领域:
材料科学
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化学
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生物医学工程
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环境科学
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高影响因子
危险品化学品经营许可证（带存储）