Nature Communications
·
2025
·
IF 15.7
Yang Sinian,Zhao Shunshun,Xu Haojie,Wang Xinwei,Huang Xuanrui,Yang Qi,Chen Yong,Wang Guoxiu,Chen Shimou
Aqueous zinc-ion batteries have emerged as a promising system for safe and sustainable energy storage. However, their practical application is hindered by detrimental interfacial side reactions and inadequate low-temperature performance. Herein, we report the design of a gradient chaotropic ionic liquid (IL)-based aqueous electrolyte (Emim⁺-TFA⁻/OTf⁻-Zn 2+ -H 2 O), which can simultaneously fulfil the conflicting demands of dendrite-free zinc deposition and low-temperature operation. By forming an antifreeze electrolyte with a hydrophobic yet salt-philic interface, the proposed formulation overcomes the limitations of conventional IL-based systems that rely on H 2 O-lean compositions, complex additives, or elaborate solvent mixtures. Thus, the assembled zinc-ion cells exhibit improved zinc plating/stripping stability. At a current density of 0.1 mA cm −2 and 0.1 mAh cm −2 , the Zn | |Zn symmetric cells endure prolonged zinc plating/stripping, exceeding 13,000 h at −30 °C and 6690 h at −40 °C. In full cells, Zn | |VO 2 @VO maintains nearly 100% capacity retention over 3500 cycles at 0.2 A g −1 and −40 °C. This gradient chaotropic Zn 2+ electrolyte design provides a versatile platform for effective antifreeze Zn 2+ solvation chemistry and accelerated interfacial ion transport, enabling high-performance zinc batteries in subzero environments.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 11
·5034-5042
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IF 3.925
Fubin Fu,Xueyan Zhang,Shengquan Zhou,Wei Shi,Jiangmin Li,Jiajia Yu,Yanzhao Rao,Lei Wu,Jing Cao
In this work, we designed two non-salen coumarin Schiff base chiral fluorescent probes 3,3′-((1E,1′E)-(((1,2)-cyclohexane-1,2-diyl)bis(azaneylylidene))bis(methaneylylidene))bis(7-methoxy-2H-chromen-2-one) (L1) and 3,3′-((1E,1′E)-(((1,2)-cyclohexane-1,2-diyl)bis(azaneylylidene))bis-(methaneylylidene))bis(2H-chromen-2-one) (L2), which have outstanding circular dichroic CD signals but almost show no circularly polarized luminescence (CPL) signals. By adding metal ions that can effectively inhibit photo-induced electron transfer (PET), it was observed that L1 can be used as a highly sensitive dual detection ion probe for Mg2+ and Zn2+ as Mg2+ and Zn2+ can turn on the CPL emission of L1. Moreover, (S,S)-L1 has exquisite recognition ability for the enantiomer of the chiral drug D/L-camphorsulfonate and showed reversible fluorescence “on/off” response with Zn2+ and EDTA. It was also found that L2 manifested selective recognition ability for Zn2+.
研究领域:
化学
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分析化学
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光学
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高影响因子
Membranes
·
2025
·Vol. 15
·期 9
·277
·
IF 3.6
Lei Ni,Qiancheng Cui,Zhe Wang,Xueting Zhang,Jun Ma,Wenjuan Zhang,Caihong Liu
The inherent hydrophobicity of poly(vinylidene fluoride) (PVDF) ultrafiltration membranes leads to severe membrane fouling when processing proteinaceous solutions and organic contaminants, significantly limiting their practical applications. This study presents a novel metal-ion mediated co-deposition strategy for fabricating high-performance antifouling poly(vinylidene fluoride) (PVDF) hollow fiber ultrafiltration membranes. Through Zn2+coordination-driven self-assembly, a uniform and stable composite coating of dopamine (DA), tannic acid (TA), and ZIF-8 nanoparticles was successfully constructed on the membrane surface under mild conditions. The modified membrane exhibited significantly enhanced hydrophilicity, with a water contact angle of 21° and zeta potential of −29.68 mV, facilitating the formation of a dense hydration layer that effectively prevented protein adhesion. The membrane demonstrated exceptional separation performance, achieving a pure water permeability of 771 L/(m2∙h∙bar) and bovine serum albumin (BSA) rejection of 97.7%. Furthermore, it showed outstanding antifouling capability with flux recovery rates exceeding 83.6%, 74.7%, and 71.5% after fouling by BSA, lysozyme, and ovalbumin, respectively. xDLVO analysis revealed substantially increased interfacial free energy and stronger repulsive interactions between the modified surface and protein foulants. The antifouling mechanism was attributed to the synergistic effects of hydration layer formation, optimized pore structure, additional water transport pathways from ZIF-8 incorporation, and electrostatic repulsion from negatively charged surface groups. This work provides valuable insights into the rational design of high-performance antifouling membranes for sustainable water treatment and protein separation applications.
研究领域:
膜科学与技术
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环境工程
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材料化学
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分离科学
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水处理技术
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生物材料
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纳米材料应用
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界面工程
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PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Xiaoyu Yuan,Ran Tang,Zhi Jia,Yutong Chen,Jie Liu,Yanan Liu
The current focus on inhibiting β-Amyloid (Aβ) aggregation has shown great limitations for the management of Alzheimer's disease (AD). Multi-target strategies that synergistically exert neuroprotective effects and alleviate oxidative stress are effective strategies to modulate the AD microenvironment. Herein, a novel Zn 2+ -responsive nano-drug delivery platform (NWP) is developed using palladium nanoclusters (Pd NCs) as carriers, loaded with nerve growth factor (NGF), capped by supramolecular nanovalves containing carboxyl pillars[5]arenes (WP5) for the treatment of AD. Pd NCs have both OH elimination and catalase activities to alleviate oxidative stress. The larger specific surface area could significantly improve the loading capacity of NGF. The supramolecular nanovalve constructed by WP5 achieves precise targeting and controlled release of NGF with Zn 2+ responsiveness, thereby improving the utilization of loading drugs. In vitro and in vivo experiments demonstrates that NWP effectively scavenges reactive oxygen species (ROS), protects neuronal cells from oxidative damage and modulates microglial polarization (the pro-inflammatory M1-phenotype microglial transition to the anti-inflammatory M2-phenotype), thus reducing the release of pro-inflammatory factors and alleviating neuroinflammation. Furthermore, intracerebral injection of NWP significantly ameliorates the learning and memory deficits of AD model mice. Overall, this Zn 2+ -responsive multi-target therapy provides a new option for AD.
研究领域:
神经科学
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纳米技术
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药学
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生物医学工程
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高影响因子
CHINESE JOURNAL OF CHEMICAL ENGINEERING
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2022
·
IF 3.898
Guangyuan Chen,Tong Zhou,Meng Zhang,Zhongxiang Ding,Zhikun Zhou,Yuanhui Ji,Haiying Tang,Changsong Wang
Struvite (MAP) crystallization technology is widely used to treat ammonia nitrogen in waste effluents of its simple operation and good removal efficiency. However, the presence of heavy metal ions in the waste effluents causes problems such as slow crystallization rate and small crystal size, limiting the recovery rate and economic value of the MAP. The present study was conducted to investigate the effects of concentrations of three heavy metal ions (Cu 2+ , Zn 2+ , and Pb 2+ ) on the crystal morphology, crystal size, average growth rate, and crystallization kinetics of MAP. A relationship was established between the kinetic rate constant K t calculated by the chemical gradient model and the concentrations of heavy metal ions. The results showed that low concentrations of heavy metal ions in the solution created pits on the MAP surface, and high level of heavy metal ions generated flocs on the MAP surface, which were composed of metal hydroxides, thus inhibiting crystal growth. The crystal size, average growth rate, MAP crystallization rate, and kinetic rate constant K t decreased with the increase in heavy metal ion concentration. Moreover, the K t demonstrated a linear relationship with the heavy metal concentration ln( C / C* ), which provided a reference for the optimization of the MAP crystallization process in the presence of heavy metal ions.
研究领域:
环境科学
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化学工程
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水处理
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高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2023
·
IF 5.8
Bo Zhou,Ben-Xu Jia,Ming-Jin Zhang,Yan-Jun Tan,Wei-Yuan Liang,Xiang Gan,Hong-Tao Li,Xiaoli Yang,Xing-Can Shen
Zn 2+ and H 2 S are essential to maintain normal prostate function, and sometimes can evolve into weapons to attack and destroy prostate cancer (PCa) cells. Nevertheless, how to achieve the targeted and effective release of Zn 2+ and H 2 S, and reverse the concentration distribution within PCa tumor cells still highly challenging. Herein, combined with these pathological characteristics of prostate, we proposed a tumor microenvironment (TME) responsive Zn 2+ -interference and H 2 S-mediated gas synergistic therapy strategy based on a nanoplatform of tannic acid (TA) modified zinc sulfide nanoparticles ( [email protected] ) for the specific treatment of PCa. Once the constructed pH-responsive [email protected] internalized by cancer cells, it would instantaneously decomposed in acidic TME, and explosively release excess Zn 2+ and H 2 S exceeding the cell self-regulation threshold. Meanwhile, the in situ produced Zn 2+ and H 2 S synergistic enhancement of cell apoptosis, which is evidenced to increase levels of Bax and Bax/Bcl-2 ratio, release of Cytochrome c in cancer cells, contributing to inhibit the growth of tumor. Moreover, the TA in cooperation with Zn 2+ specifically limits the migration and invasion of PCa cells. Both in vitro and in vivo results demonstrate that the Zn 2+ -interference in combination with H 2 S-mediated gas therapy achieves an excellent anti-tumor performance. Overall, this nanotheranostic synergistic therapy provides a promising direction for exploring new strategies for cancer treatment based on specific tumor pathological characteristics, and provides a new vision for promoting practical cancer therapy.
研究领域:
癌症生物学
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纳米医学
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诊疗学
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药学
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Xiaoting Yu,Shanghua Xing,Mingqian Tan
Nanoparticles (NPs) possessing nanoscale dimensions and remarkable antioxidant activity were synthesized via a green hydrothermal method utilizing Auricularia auricula fermentation broth, referred to as AFNPs. The functional groups on the surface of the AFNPs significantly contributed to the formation of AFNPs-Zn 2+ . The AFNPs-Zn 2+ appeared a zinc retention rate of 40.80 % after gastrointestinal digestion. When compared to typical zinc supplements, AFNPs-Zn 2+ did not exhibit visible cytotoxicity or hemolysis. Furthermore, AFNPs-Zn 2+ demonstrated the ability to mitigate cell damage resulting from zinc deficiency. In vivo experiments showed that AFNPs-Zn 2+ were mainly observed in the stomach, intestine, kidney, and testis after oral administration. In vivo distribution experiments indicated predominant presence of AFNPs-Zn 2+ in the stomach, intestine, kidney, and testis following oral administration. This study highlights the potential for Auricularia auricula NPs to serve as the efficient, stable, and safe nanocarriers for Zn 2+ .
研究领域:
纳米技术
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材料科学
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生物技术
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营养学
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毒理学
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PubMed
高影响因子
SOLAR ENERGY MATERIALS AND SOLAR CELLS
·
2020
·
IF 6.984
Qingyi Huang,Sheng Cao,Yuwei Liu,Yi Liang,Juquan Guo,Ruosheng Zeng,Jialong Zhao,Bingsuo Zou
Zn 2+ -based electrochromic is a newly born technology in recent years and has attracted the attention of most researchers due to its low cost and high safety. The design of high-performance Zn 2+ -based electrochromic devices , such as large light modulation and fast color change, is still a challenge. Here, we report the improvement of Zn 2+ -based electrochromic properties by morphology control, using common electrochromic material WO 3 as the research model. The hexagonal WO 3 films with shape of nanorods and nanoflakes were prepared by hydrothermal method , where the diameter of the nanorods and the thickness of the nanoflakes are almost the same. The electrochromic characterization of WO 3 nanorods and nanoflakes at 550 nm showed that their modulation ranges were 72.4% and 61.0%, their coloration times were 3 and 9 s, their bleaching times were 2.2 and 7 s, and their coloration efficiencies were 67.6 and 53.8 cm 2 C -1 , respectively. Compared with WO 3 nanoflakes, the excellent Zn 2+ -based electrochromic properties of WO 3 nanorods show rapid electron transfer kinetics caused by large surface area. Furthermore, the prototype electrochromic devices with WO 3 nanorods were fabricated, which showed good specific capacitance and excellent electrochromic performance. The fast and large optical modulation synchronous as well as good energy storage makes the electrochromic device become a potential intelligent power supply. This morphology dependent electrochromic work provides a new vision for the construction of high-performance Zn 2+ - based electrochromic devices.
研究领域:
材料科学
·
电化学
·
纳米技术
·
能源存储
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Mengwei Han,Yuzhu Qian,Xinni Li,Nailiang Wang,Ting Song,Li Liu,Xianyou Wang,Xiongwei Wu,Man-Kay Law,Bei Long
Developing insertion-type anode is key to advancing “rocking chair” zinc-ion batteries, though there are few reported insertion-type anodes. Herein, the Bi 2 O 2 CO 3 is a high-potential anode, with a special layered structure. A one-step hydrothermal method was used to prepare Ni-doped Bi 2 O 2 CO 3 nanosheet , and also a free-standing electrode consisting of Ni-Bi 2 O 2 CO 3 and CNTs was designed. Both cross-linked CNTs conductive networks and Ni doping improve charge transfer. Ex situ tests (XRD, XPS, TEM, etc.) reveal the H + /Zn 2+ co-insertion mechanism of Bi 2 O 2 CO 3 and that Ni doping improves its electrochemical reversibility and structural stability. Therefore, this optimized electrode offers a high specific capacity of 159 mAh g −1 at 100 mA g −1 , a suitable average discharge voltage of ≈0.400 V, and a long-term cycling stability of 2200 cycles at 700 mA g −1 . Besides, the Ni-Bi 2 O 2 CO 3 //MnO 2 “rocking chair” zinc-ion battery (based on the total mass of cathode and anode) delivers a high capacity of ≈100 mAh g −1 at 50.0 mA g −1 . This work provides a reference for designing high-performance anode in zinc-ion batteries.
研究领域:
材料科学
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电化学
·
能源存储
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DOI
高影响因子
Advanced Science
·
2023
·
IF 15.1
Lin Ding,Minli Liang,Yuanyuan Li,Mei Zeng,Meiting Liu,Wei Ma,Fuming Chen,Chenchen Li,Rui L. Reis,Fu-Rong Li,Yanli Wang
Tumor extracellular matrix (ECM) not only forms a physical barrier for T cells infiltration, but also regulates multiple immunosuppressive pathways, which is an important reason for immunotherapy failure. The cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) pathway plays a key role in activating CD8 + T cells, maintaining CD8 + T cells stemness and enhancing the antitumor effect. Herein, a zinc-organometallic framework vaccine (ZPM@OVA-CpG) prepared by self-assembly, which achieves site-directed release of Zn 2+ in dendritic cell (DC) lysosomes and tumor microenvironment under acidic conditions, is reported. The vaccine actively targets DC, significantly enhances cGAS-STING signal, promotes DC maturation and antigen cross-presentation, and induces strong activation of CD8 + T cells. Meanwhile, the vaccine reaches the tumor site, releasing Zn 2+ , significantly up-regulates the activity of matrix metalloproteinase-2, degrades various collagen components of tumor ECM, effectively alleviates immune suppression, and significantly enhances the tumor infiltration and killing of CD8 + T cells. ZPM@OVA-CpG vaccine not only solves the problem of low antigen delivery efficiency and weak CD8 + T cells activation ability, but also achieves the degradation of tumor ECM via the vaccine for the first time, providing a promising therapeutic platform for the development of efficient novel tumor vaccines.
研究领域:
癌症免疫学
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药学
·
生物医学工程
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分子生物学
·
免疫疗法
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PubMed
高影响因子
JOURNAL OF POWER SOURCES
·
2019
·
IF 7.467
Hu Luo,Yingming Wang,Gongwei Wang,Li Xiao,Juntao Lu,Lin Zhuang
Redox electrochemical capacitors , using soluble redox couples to utilize the “dead weight” of the electrolyte to add faradaic charge, are considered as an effective strategy to increase the energy storage capacity of the electro-chemical double-layer capacitors. In this work, we report a new aqueous dual-redox electrochemical capacitor, using Zn 2+ /Zn as the anolyte and Br 3 ˉ/Brˉ as the catholyte. The electrolyte contains 1 M ZnBr 2 , 0.1 M TPABr and 2 M Zn(OTf) 2 . The theoretical voltage gap of the two redox couples is larger than 1.7 V, which is expected to be an advantage for higher specific energy. Tetrapropyl ammonium cation (TPA + ) has been used as a complex agent to solve the Br 3 ˉ cross diffusion issue. To avoid the generation of [TPA] 2 [ZnBr 4 ] precipitation, an appropriate amount of Zn(OTf) 2 has been added to the electrolyte to adjust the Zn/Br ratio. After adding these two additives, the coulombic efficiency of the dual-redox EC has been increased from 90% to 99%, and the open-circuit voltage loss (24 h) has been dropped from 31% to 5%. The newly configured Zn/OTf/TPA/Br redox EC exhibits a specific energy of 110 W h/kg at 1 A/g, a high power density (7 kW/kg) and stable cycling over 6000 cycles.
研究领域:
电化学
·
能源存储
·
材料科学
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DOI
高影响因子
ENVIRONMENTAL POLLUTION
·
2019
·
IF 5.714
Xing Cao,Weibing Wang,Rui Ma,Shichang Sun,Junhao Lin
In order to exhaustively investigate the physical and chemical mechanisms of heavy metal immobilization in sludge incineration residue (SIR)-based magnesium potassium phosphate cement (MKPC), this work investigated the influence of Pb 2+ and Zn 2+ on the compressive strength and microstructure of SIR-based MKPC, and the efficiency of Pb and Zn immobilization. Taking the difference of Ksp (solubility product) of different heavy metal compounds as the entry point, the physical and chemical mechanisms of Pb and Zn immobilization, and the competitive mechanism between coexisting ions, were comprehensively analyzed. It was discovered that Pb 2+ is in the form Pb 3 (PO 4 ) 2 , and Zn 2+ is immobilized in the form Zn 2 (OH)PO 4 [Zn 3 (PO 4 ) 2 is preferentially formed, when the pH > 7, Zn 3 (PO 4 ) 2 is converted to Zn 2 (OH)PO 4 ]. The low solubility of heavy metal phosphates is the main reason that Pb 2+ and Zn 2+ are well immobilized. The preferential formation of Pb 3 (PO 4 ) 2 (K sp = 8 × 10 −43 ) and Zn 3 (PO 4 ) 2 (K sp = 9.0 × 10 −33 ) reduced the amount of MgKPO 4 ·6H 2 O (K sp = 2.4 × 10 −11 ), resulting in a decrease in compressive strength. Besides, coexisting Pb 2+ and Zn 2+ has a competitive effect: Pb 2+ will weaken the immobilization efficiency of Zn 2+ . The new exploration of these mechanisms provide a theoretical basis for rationally adjusting the Magnesia/Phosphate ratio to enhance the compressive strength and improve the efficiency of heavy metals immobilization.
研究领域:
环境科学
·
材料科学
·
化学工程
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PubMed
高影响因子
危险品化学品经营许可证（带存储）