CHEMICAL ENGINEERING JOURNAL
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2026
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IF 12.5
Qiang Zhou,Jian Wang,Yangmingxu Meng,Yi Li,Xianglong Zhao,Zexuan Meng,Jiuxi Sui,Lu Yang,Jiajia Chen,Xuanbing Wang,Ji Gong,Guangqiang Pan,Yuchan Zhang,Guangchao Zang
Silicon carbide (SiC) nanoelectrodes show promise for intracellular molecule monitoring but face challenges due to high resistance and chemical inertness, which necessitate functional surface modification to improve detection Performance. In this study, we address the bottlenecks of insufficient functional groups in nanowires prepared by traditional chemical vapor deposition (CVD) and poor conductivity of polymer modification methods, via a novel conductive functionalized hydrothermal carbon coating (HTCC) interface engineering approach. Rooted in the inherent tendency of carbon nanospheres to self-assemble and adhere tightly via intermolecular interactions during hydrothermal synthesis, the approach uniformly coats the surface of inert SiC nanowires with a hydrothermal carbon layer endowed with high conductivity, stability, and abundant functional groups. The Pt/Pd-Cs-HTCC@SiC constructed based on this strategy has been successfully applied to the in-situ monitoring of intracellular reactive oxygen species (ROS), revealing the mechanism by which glutathione (GSH) blocks tau protein phosphorylation by inhibiting the p38 mitogen-activated protein kinase (p38-MAPK) pathway, thereby alleviating the hepatotoxicity of microcystin-LR (MC-LR). This study provides a surface engineering approach for SiC nanoelectrodes and offers crucial scientific insight into the hepatotoxicity mechanisms of environmental toxins.
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MICROCHEMICAL JOURNAL
·
2026
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IF 5.2
Mengjie Su,Aiteng Zhou,Zijian Chen,Mengwei Li,Yi Yao,Zhengyuan Ding,Yaqiu Zhou,Qianying Qiu,Chunmei Yu
For promptly reflecting heavy metal exposure and accumulation levels in human body, flexible electrochemical sensing platforms based on sweat analysis have garnered significant attention ascribed to their ability to non-invasively monitor sweat heavy metal levels. Here, a flexible electrochemical sensor on the basis of antimony nanoparticle (AMNP) modified screen-printed electrode (SPE) was developed for the simultaneous detection of Zn and Pb ions in sweat. The synthesized AMNP with high specific surface area and excellent electrocatalytic performance possessed satisfied adsorption and enrichment capacity for Zn and Pb ions, while markedly amplified stripping voltametric signals. The detection range of the sensor covered the normal physiological concentration range of sweat Zn and Pb ions. The sensor successfully achieved in-situ measurement of trace Zn and Pb ions in sweat, and the results were verified using inductively coupled plasma mass spectrometry (ICP-MS) with satisfactory consistency. This electrochemical sensing platform offers an accessible and non-invasive strategy for the monitoring of heavy metal ions in sweat, opening up possibilities for creating wearable devices applied for assessing health conditions and clinical diagnosis as well as treatment related to heavy metal exposure.
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ULTRASONICS SONOCHEMISTRY
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2026
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IF 10.2
Shuai Wang,Haiping Sun,Xiyu Lv,Jingna Li,Defeng Du,Fei Guo,Chao Zhang
Fructus Tribuli (FT), the dried ripe fruit of Tribulus terrestris L., is recognized for its antihypertensive properties, which are enhanced by stir-frying without adjuvants. However, research on its polysaccharides with therapeutic potential remains limited. This study optimized the ultrasound-assisted extraction (UAE) of FT polysaccharides (FP) using response surface methodology, yielding a maximum extraction yield of 2.182 ± 0.29% under the conditions of liquid–solid ratio 20:1 mL/g, 51 min, 62 °C, and precipitation ethanol concentration of 95%. Subsequently, FP and stir-fried FT polysaccharides (SFP) were isolated, and their structural differences and antihypertensive effects were systematically compared. Structural analysis revealed notable differences between FP and SFP. Furthermore, the extraction resulted in a higher polysaccharide yield for SFP. In spontaneously hypertensive rats, both FP and SFP attenuated hypertension and vascular injury, modulated gut microbiota, increased short-chain fatty acids, and enhanced intestinal barrier function effects that were more pronounced with SFP. Mechanistically, both polysaccharides inhibited the aortic TLR4/MyD88 pathway. These results suggest that stir-frying modifies polysaccharide structure, thereby improving gut microbiome regulation, barrier protection, and vascular outcomes, highlighting the value of processing in enhancing polysaccharide efficacy. Thus, stir-frying amplifies therapeutic effects through bioactive macromolecular remodeling, advancing the understanding of Traditional Chinese medicine processing principles.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2026
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IF 6.7
Lijuan Meng,Wenwen Zhang,Guoyan Mo,Yu Gao,Lu Cao,Huabing Yang,Tianxiang Zhu,Lei Xiong,Hongtao Liu
Xyloglucan oligosaccharides (XyGOs) are emerging prebiotics with limited sustainable production strategies. Here, two endoxyloglucanases, XyGH5 and XyGH74, from the bacterium Paenibacillus sp. XP01 were identified. Genetic knockout revealed their synergistic role in bacterial growth on xyloglucan. Biochemical characterization showed that XyGH74 exhibited superior activity (Vmax = 76.25 U/mg) and thermal stability (optimum at 70 °C) compared to XyGH5, with its carbohydrate-binding modules (CBMs) crucially enhancing catalytic efficiency and substrate affinity. We further employed the highly efficient XyGH74 to produce tamarind xyloglucan oligosaccharides (TXOS). In vitro fermentation with human gut microbiota demonstrated that TXOS significantly modulated microbial composition, enriching beneficial genera such as Bacteroides and Parabacteroides, and notably enhanced the production of short-chain fatty acids, particularly butyrate, compared to the native polysaccharide. This study provides direct genetic evidence for synergistic glycoside hydrolase function in vivo and establishes XyGH74 as a robust enzymatic tool for scalable, high-value prebiotic production with enhanced health benefits.
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PubMed
高影响因子
DRYING TECHNOLOGY
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2026
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IF 3.2
Quanquan Li,Yue Zhao,Hongwei Luan,Ying Bu,Wenhui Zhu,Xuepeng Li
The effects of air-impingement jet drying (AID) at temperature of 40–70 °C on red sea bream surimi powder were studied. Results showed that water activity was below 0.5 in all groups. Total volatile basic nitrogen (TVB-N) levels were significantly below 30 mg/100 g. The 40 °C treatment group showed the most uniform surface morphology after rehydration, with the highest water-holding capacity (WHC) and gel strength. Fourier transform infrared (FTIR) spectroscopy revealed changes in C–H, C = O, C = C, and CH2 groups. Lactic acid, citric acid, and succinic acid contributed significantly to the taste, while 5′-nucleotides contributed relatively less. Electronic tongue showed that T40 was more bitter and aftertaste, while the electronic nose revealed that T70 had higher levels of inorganic sulfides, nitrogen oxides, short-chain alkanes, and aromatic compounds. Overall, T50 represents the optimal conditions for AID-dried surimi powder. These findings provide a scientific foundation for optimizing the AID drying process.
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FOOD MICROBIOLOGY
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2026
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IF 5.4
Qifeng Wu,Nana Zhang,Yichun Sun,Zhengfang Qi,Rongrong Zhang,Anyan Wen,Likang Qin,Haiying Zeng
Targeted enrichment of tocopherols in fungal fermentation systems remains a significant metabolic engineering challenge. This study presented a novel strategy employing homogentisic acid (HGA) modulation to efficiently enhance tocopherol production in the M. purpureus -fermented coix seed (MFCS) system. Three strategies of exogenous HGA supplementation (Exo-HGA), endogenous HGA accumulation (End-HGA), and the combination of exogenous HGA supplementation and endogenous HGA accumulation (Exo+End-HGA) were systematically investigated. While End-HGA optimally promoted lovastatin, pigment, and biomass, the Exo+End-HGA strategy (supplemented with 250 ug/mL Exo-HGA) achieved superior tocopherol enrichment. The contents of total, α-, and γ-tocopherol reached 225.407, 64.022, and 161.385 μg/mL, respectively, corresponding to a 1.86-fold increase in total tocopherol compared with the control group. A total of 2,425 differentially expressed metabolites were identified. The significant accumulation of HGA, concomitant increases in γ-tocotrienol and menatetrenone (VK2), along with a decline in ubiquinone precursors such as 4-hydroxybenzoic acid derivatives, suggested that HGA specifically activated the tocopherol biosynthesis pathway. KEGG pathway analysis further revealed that HGA upregulated the shikimate and methylerythritol phosphate/mevalonate (MEP/MVA) pathways, thereby coordinating the redistribution of carbon flux and repressing competing routes such as phenylpropanoid and alkaloid biosynthesis, ultimately facilitating tocopherol enrichment. This study elucidated the metabolic network underlying HGA-mediated tocopherol enrichment in MFCS, providing a the oretical foundation and potential targets for enhancing tocopherol production through microbial metabolic engineering strategies.
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PubMed
高影响因子
FOOD RESEARCH INTERNATIONAL
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2026
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IF 8.8
Bo Li,Lin Zhang,Ding-Tao Wu,Qin Yuan,Shengpeng Wang,Mao-Ling Tan,Mei-Lin Feng,Yi-Chen Hu,Liang Zou,Zi-Peng Wang,Ya-Nan Cao,Jing-Wei Huang
Tartary buckwheat sprout pectic polysaccharides (TP) have demonstrated notable immunostimulatory activity in vitro. Nevertheless, the in vivo function and how structural features dictate its immunostimulatory activity through gut microbiota modulation are still unclear. To fill this gap in our understanding, we compared in vivo immunostimulatory effects of TP and its derivatives featuring key structural modifications: a lower esterification degree (TP-LDE: 4.72% vs. TP: 28.04%) or a lower molecular mass (TP-LMW: 0.957 × 10 4 Da vs. TP: 8.191 × 10 4 Da). Results demonstrated that TP and its derivatives (TP-LDE, TP-LMW) counteracted cyclophosphamide (CTX)-induced immunosuppression by restoring gut microbiota balance, short-chain fatty acid (SCFA) levels, intestinal barrier function, and systemic immunity. Notably, the derivatives, particularly TP-LMW, exhibited superior immunostimulatory activity to the native TP in enhancing serum cytokines (TNF-α and IFN-γ) and serum immunoglobulin IgA, promoting SCFA (propionic acid and butyric acid) production, and maintaining intestinal barrier function (enhanced expression of ZO-1 and occludin), confirming that reducing either the molecular mass or the esterification degree enhances TP's immunostimulatory potency. Furthermore, all treatments reversed CTX-induced dysbiosis by increasing Muribaculaceae while suppressing dysbiosis-linked genera (e.g., Lachnospiraceae_NK4A136_group , Colidextribacter , and Oscillibacter ). In contrast, only TP-LDE uniquely and significantly enriched the beneficial genera Bacteroides , Prevotellaceae_UCG_001 , and Parabacteroides . Taken together, this work elucidates how structural features govern the immunostimulatory activity of TP, which provides a foundation for developing TP and its derivatives into functional foods for improving and maintaining host immunity.
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JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
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2026
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IF 3.4
Wang Yue,Tang Xiaohan,Zhao Huarong,Pan Yue,Zhang Dingnan,Liu He,Zhu Danshi
Most studies only preliminarily assessed the effects of non-grain supplemental levels on the physicochemical and nutritional properties of steamed bread, and few further analyzed the ways to improve its quality by changing the properties of raw materials themselves. This study investigated the effect of Monascus -fermented autoclaved whole soybean flour (FAWSF) and autoclaved whole soybean flour (AWSF) as wheat flour substitutes in making steamed bread. The contents of protein and soluble dietary fiber were higher in FAWSF than in AWSF. Steamed bread substituted with FAWSF significantly reduced the degree of crystallization and retrogradation. Furthermore, the steamed bread with 5% FAWSF was better than the control in terms of specific volume, texture, total phenolic content, and soybean isoflavones, improving the overall quality of steamed bread. Therefore, FAWSF is a promising new food ingredient.
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Food Analytical Methods
·
2026
·Vol. 19
·期 4
·138
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IF 3
Wang Hui,Wang Zhaoxia,Qin Jijun,Zhong Feifei,Kong Xiangling,Chen Meimei,Han Shilei,Zhang Lei,Yuan Yuan,Yin Fangping,Zhou Peng
This study developed a comprehensive strategy to identify and quantify a novel vardenafil analogue, SLX-2101, which was detected as an undeclared adulterant in functional foods. The compound was initially screened and characterized using ultra-performance liquid chromatography–quadrupole time-of-flight mass spectrometry (UHPLC-UV-Q-TOF/MS), and its structure was confirmed via nuclear magnetic resonance (NMR) spectroscopy and comparison with a custom-synthesized reference standard. A quantitative ultra-performance liquid chromatography–tandem mass spectrometry (UHPLC-QqQ/MS) method was established and validated, demonstrating good linearity (1.0–100.0 μg/L, r > 0.997), with a limit of detection of 0.3 μg/kg and a limit of quantification of 1.0 μg/kg. Mean recoveries ranged from 74.2% to 115.8% across various food matrices, with relative standard deviations between 0.4% and 12.5%. Application to 61 commercial samples revealed SLX-2101 in two functional wines marketed for their purported aphrodisiac effects at concentrations of 19.3 mg/kg and 1.3 × 10 3 mg/kg. The validated method enables reliable surveillance of this emerging adulterant, thereby providing a practical solution to address the critical gap left by conventional targeted screening protocols.
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 3
·209
·
IF 5.4
Li Shaohui,Hao Sijia,Li Wen,Meng Ran,Wang Qiang,Wang Yuqing,Wang Lei,Liu Xinjing,Zhou Yuanyuan,Wang Haitong,Zhang Dongxia,Zhou Xibin
A ternary structure (CuO/CN/LDH) composed of LDH-anchored g-C 3 N 4 nanosheets loaded with CuO nanoparticles was successfully constructed via hydrothermal and co-precipitation methods, and a colorimetric sensing platform for hexavalent chromium (Cr(VI)) detection was proposed. The engineered nanomaterial demonstrates significantly enhanced oxidase-mimetic activity in the presence of Cr(VI), enabling rapid catalytic oxidation of 3,3’,5,5’-tetramethylbenzidine (TMB) with distinct chromogenic response. Mechanistic investigations reveal that Cr(VI) facilitates the conversion of dissolved oxygen into superoxide anions via redox cycling, thereby accelerating TMB oxidation. The sensor exhibits exceptional analytical performance with high accuracy (recoveries of 97.3-103.8%) and sensitivity (detection limit of 25 nM) in aqueous sample analysis. The sensor demonstrated excellent selectivity against common interfering metal ions, as well as high stability (still above 95% for 8 weeks). Notably, an innovative paper-based analytical device was developed in conjunction with smartphone-assisted colorimetric detection, achieving on-site visual quantification of Cr(VI) within 15 min. This integrated system provides a field-deployable solution for environmental monitoring, combining operational simplicity with reliable detection capabilities. This study addresses the main limitations of Cr(VI) sensors, such as their dependence on complex instruments and poor stability of natural enzymes, and demonstrates low detection limits, excellent selectivity, and long-term stability. In addition, the proposed methodology advances current sensing technologies by merging nanomaterial engineering with portable detection platforms, demonstrating significant potential for heavy metal surveillance in water quality management. Based on this, this study also constructed a paper-based colorimetric detection sensor.
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JOURNAL OF CHEMICAL CRYSTALLOGRAPHY
·
2026
·Vol. 56
·期 1
·27
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IF 0.7
Ni Yingjia,Jin Shouwen,Hong Ruyu,Hong Huiling,Gao Rui,Wang Daqi
The hydrothermal reaction of the Cd( O Ac) 2 with the 2-methylimidazole (mim) in the presence of the monocarboxylic acids produced five unpublished mim-derived coordination compounds of Cd(mim) 2 (ibu) 2 (1) (Hibu = ibuprofen), Cd(mim) 2 (sal) 2 (2) (Hsal = salicylic acid), Cd(mim) 2 (pba) 2 (3) (Hpba = 3-phenoxybenzoic acid), Cd(mim) 2 (tba) 2 (4) (Htba = 2,4,6-trichlorobenzoic acid), and Cd(mim) 2 (tmba) 2 (5) (Htmba = 2,4,6-trimethoxybenzoic acid) and they are structurally characterized by the EA, IR spectra, TG and SCXRD analysis. The X-ray investigations declared that all these coordination compounds demonstrated the mononuclear graphs with the pseudo-tetrahedral/octahedral/square-pyramidal geometries around the Cd 2+ . The mim molecules take the coordination mode of the monodentate by only using its imidazole ring N atoms. The CO 2 − coordinated to the Cd 2+ ion in monodentate, and chelating bidentate types. The intricate intra- and intermolecular traditional H-bonds are uncovered by the X-ray crystallographic studies, which mediate the discrete systems into the 1D–2D supramolecules. Graphical Five mononuclear Cd 2+ complexes with the pseudo-tetrahedral/octahedral/square-pyramidal coordination geometries have been synthesized and characterized, the intricate intra- and intermolecular traditional H-bonds mediate the discrete systems into the 1D-2D supramolecules.
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CELLULOSE
·
2026
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IF 4.6
Xin Yasen,Wang Miaomiao,Zou Ziwei,Wang Zongde,Song Fei,Huang Chen,Wu Ting,Zou Xiuxiu
Cellulose fiber (CF) is widely used as a flexible substrate in material science and bio-medical engineering. However, a majority of traditional research focuses solely on overcoming the bottleneck of CF in mechanical properties and improving resistance characteristics attributed to self-defects, ignoring the selection of non-toxic reinforcing agent and green, efficient and scalable production demands. In this work, a clean and scalable strategy, sizing process of waterborne emulsion was proposed for reinforcing CF paper. This innovative approach focused on controlling the insertion of 2D tung oil anhydride (TOA) layer based on the thermoset of TOA in the thermal reaction to form ester bond between cellulose and TOA due to the high chemical activity of TOA. Accordingly, the extensive ester bonds between CF and TOA enhanced cross-linking density and interfacial adhesion between CF, resulting in excellent tensile strength and toughness. Particularly, TOA/CF paper showed a tensile strength of 87.62 MPa, Young's modulus of 2.98 GPa and impact strength of 31.26 kg . f/mm 2 when the added content of TOA was 7 wt%. Moreover, the TOA/CF paper exhibited better hydrophobicity (water contact angle of 117° ± 3°) and thermal stability than pure CF paper. The developed TOA/CF paper featuring green and high yield fabrication has promising applications as a flexible substrate in various industries.
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危险品化学品经营许可证（带存储）