LWT-FOOD SCIENCE AND TECHNOLOGY
·
2017
·
IF 2.329
Honest N.E. Kessy,Kai Wang,Lei Zhao,Molin Zhou,Zhuoyan Hu
Enzyme-assisted extraction and biotransformation of phenolic compounds from litchi pericarps were investigated. Pectinase, β-glucosidase and tannase were used individually and sequentially. The effects of various enzymes and hydrolysis conditions on recovery and biotransformation of phenolic compounds were evaluated. The results indicated that the optimum conditions for enzymatic extraction were 3% (w/w) of pectinase, 1% (w/w) of tannase and 1% (w/w) of β-glucosidase, incubation time and temperature were 180 min and 35 °C, respectively. Under these conditions, pectinase treatment was more efficient in liberating phenolic compounds compared to tannase and β-glucosidase. Sequential enzyme treatment produced more phenolic compounds than the untreated litchi pericarps. As revealed by HPLC, apart from the phenolic compounds observed in pectin and pectin–tannase treated litchi pericarps, quercetin was observed in the pectinase-β-glucosidase and pectinase-β-glucosidase-tannase treated samples, indicating that flavonols probably underwent transformation from glycosylated (rutin) to deglycosylated (quercetin) during sequential enzymatic treatments. Ferric reducing antioxidant power, DPPH radical scavenging capacity, and angiotensin I-converting enzyme inhibition capacity of the enzyme produced extracts were significantly improved compared to the untreated sample. These results suggest that enzyme-assisted produced extracts could be a promising ingredient in developing natural functional foods, and in pharmaceutical products against hypertension in humans.
研究领域:
食品科学
·
植物化学
·
药理学
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 33
·16183-16191
·
IF 3.925
Ping Ouyang,Rui Zhang,Jian Zhou,Haiyan Liu,Zhichang Liu,Chunming Xu,Shaojuan Zeng,Qian Su,Xiangping Zhang,Xianghai Meng
The effective electrochemical recovery of metal for bimetallic composite ionic liquid (IL) is related to the ion species and even the reaction mechanism under different Cu(I) contents. Thus, bimetallic composite ILs (Et3NHCl–1.54AlCl3–xCuCl, x = 0–0.23) were synthesized to investigate the Cu(I) speciation, voltammetric behavior and electrodeposition mechanism under different Cu(I) contents. For the cyclic voltammogram, three cathodic peaks of Et3NHCl–1.54AlCl3–0.010CuCl were related to the reduction of Cu(II) to Cu(I), Cu(I) to Cu(0), and Al(III) to Al(0), respectively. Meanwhile, for Et3NHCl–1.54AlCl3–0.23CuCl, the cathodic and anodic peaks were related to the redox reaction of copper. The whole offline detection of bimetallic composite ILs showed that the anodic reaction under low content of Cu(I) (≤ 0.60 wt%) was dominated by the generation of chlorine gas, while the cathodic reaction was related to the potential. However, when the Cu(I) content was higher than 2.23 wt%, only the disproportionation reaction of Cu(I) occurred and CuCl2 was obtained on the anode. Long-term electrodeposition showed that the effective recovery of copper from industrial bimetallic composite IL was realized. This study lays a good foundation for the clear understanding and comprehensive implementation of the resource utilization.
研究领域:
电化学
·
材料科学
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DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2020
·
IF 4.192
Li Hao,Xinchang Gao,Tingyi Zhou,Jinxuan Cao,Yangying Sun,Yali Dang,Daodong Pan
Umami peptides can help reduce the salt content in foods while still maintaining a savory taste. Few studies have reported the bioactivity of umami peptides after consumption. We studied the bioactivities of 12 umami peptides after gastrointestinal digestion. Three umami peptides exhibited angiotensin I-converting enzyme (ACE) inhibitory and antioxidant activity after digestion. Six novel peptides were identified from digestion solutions of the peptides by HPLC-MS/MS. Among them, CC, CCNK, and HCHT had both ACE inhibitory activity (IC50 values were 9.81, 9.00, and 114.99 μM, respectively) and antioxidant activity (strong 1,1-Diphenyl-2-pycryl-hydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) free radical scavenging activities). AHSVRF had strong ACE inhibitory activity. These peptides increased the nitric oxide concentration and decreased the content of endothelin-1 in a medium of human umbilical vein endothelial cells in a dose-dependent manner. Experiments with damaged HepG2 cells showed that peptides CC, CCNK, and HCHT had antioxidant activity through their cytoprotective effects and by reducing the reactive oxygen species content. The results indicated that umami peptides may provide many health benefits after consumption.
研究领域:
食品科学
·
营养学
·
生物化学
·
药理学
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DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2020
·
IF 6.785
Jiao Cao,Shanyu Zhang,Jinyue Zhang,Sha Wang,Wendong Jia,Shuanghong Yan,Yuqin Wang,Panke Zhang,Hong-Yuan Chen,Shuo Huang
Gold(I) compounds are known to bind sulfur-containing proteins, forming the basis in the design of gold(I)-based drugs. However, the intrinsic molecular mechanism of the chemical reaction is easily hidden when monitored in ensemble. We have previously demonstrated that Mycobacterium smegmatis porin A (MspA) can be engineered (MspA-M) to contain a specialized nanoreactor to probe chemical reactions involving tetrachloroaurate(III). Here, we provide further investigations of coordination interactions between dichloroaurate(I) and MspA-M. Gold compounds of different coordination geometry and valence states are as well probed and evaluated, demonstrating the generality of MspA-M. With single-molecule evidence, MspA-M demonstrates a preference for dichloroaurate(I) than tetrachloroaurate(III), an observation in a single molecule that has never been reported. By counting the maximum number of simultaneous ion bindings, the narrowly confined pore restriction also efficiently distinguishes dichloroaurate(I) and tetrachloroaurate(III) according to their differences in geometry or size. The above demonstration complemented a previous study by demonstrating other possible gold-based single-molecule chemical reactions observable by MspA. These observations bring insights in the understanding of gold-based coordination chemistry in a nanoscale.
研究领域:
化学
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纳米技术
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生物物理学
·
材料科学
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DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2020
·
IF 5.977
Dengwang Luo,Chaoyu Zhang,Yao Fang,Yiping Shen,Yuan Liang,Yaokun Xia,Fang Wu,Xiaosong Chen,Jingrong Liu,Jinghua Chen,Chunyan Li,Jianming Lan
Phospholipase A 2 (PLA 2 ) may be a vital biomarker for the prediction and diagnosis of some diseases. Consequently, it is of great significance to quantitatively detect PLA 2 in biologic samples. Herein, on the basis of the principle of luminescence resonance energy transfer (LRET) between upconversion nanoparticles (UCNPs) and SYBR Green I (SG), we proposed a technology for the highly sensitive detection of PLA 2 amount. Therein, as an energy receptor, SG will be quantitatively loaded into liposomes firstly. Then, due to the hydrolysis of liposomes under the catalysis of PLA 2 , SG will be released and inserted into the double-stranded DNA (dsDNA) on the surface of UCNPs, which triggers the LRET because of the shortening of effective spatial distance between UCNPs and SG. Under exciting of NIR light, UCNPs emit luminescence at 476 nm, which makes SG emit fluorescence at 522 nm through LRET. Under optimal conditions, the emission intensity ratio (I 522 nm /I 476 nm ) increased linearly with the PLA 2 amount in the range of 20 U/L to 400 U/L, and the limit of detection (LOD) reached 15 U/L. Here, after comparing with the clinical standard method, it is found that the biosensor is expected to provide a convenient and sensitive assay for the detection of PLA 2 in actual serum samples. Furthermore, such biosensor can also be used to test the inhibitor of PLA 2 .
研究领域:
生物技术
·
分析化学
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纳米技术
·
医学诊断
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DOI
PubMed
高影响因子
MATERIALS & DESIGN
·
2020
·
IF 6.289
Xuefeng Zhou,Xi Cheng,Danlei Xing,Qi Ge,Yan Li,Xianghong Luan,Ning Gu,Yunzhu Qian
Bioactive synthetic scaffolds with 3D porous structure are the most attractive materials among various guided bone regeneration membranes. However, its osteogenic potential is still insufficient. This study was aimed to develop a Calcium surface-anchored Collagen I-PLGA/PCL scaffolds (PP/COL I-pDA-Ca) with enhanced osteogenicity. PP/COL I-pDA-Ca was electrospun from a collagen I-blended PLGA/PCL matrix and then modified by the chelation of Ca-ions via mussel-inspired polydopamine coating. PLGA/PCL, PLGA/PCL-polydopamine, PLGA/PCL-pDA chelated by Ca-ions were used as controls. Osteogenic effects of the scaffolds were examined using MC3T3-E1 cell culture. PP/COL I-pDA-Ca maintained 3D porous architecture with interconnected pores formed by randomly-oriented filamentous fibers and MC3T3-E1 cells cultured on it for 12 h or 24 h were more stretched and spread than those on the controls. PP/COL I-pDA-Ca significantly upregulated α10, α11 and β1 integrin expression after 48 h culture. ALP activity, OCN, OSX, BMP2 and RUNX2 expression of MC3T3-E1 cells cultured on PP/COL I-pDA-Ca scaffolds for 7 and 14 days were substantially enhanced when compared to controls ( p < 0.05). The pDA-based Ca chelation, COL I incorporation and 3D bionic structure promoted cell adhesion and osteogenic differentiation of MC3T3-E1 cells. This novel PP/COL I-pDA-Ca scaffolds is an attractive alternative for guided bone regeneration.
研究领域:
生物材料
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组织工程
·
生物医学工程
·
骨科
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Qingxin Ge,Zhou Zhou,Jing Li,Xiangyang Qu,Qiaoqiao Fang,Zhiliang Han,Rongliang Wu,Huaping Wang,Shiyan Chen
Given the widespread availability of low-grade heat (< 100 °C), its conversion into electricity represents a highly promising green technology. Thermo-electrochemical cells (TECs) have garnered significant attention for their potential in low-grade thermal energy harvesting, largely due to their relatively high thermopower. An efficient approach to achieve high thermopower is establish a high and stable concentration gradient (∆C). However, the ∆C construction process is often limited by a false saturation state in conventional I − /I 3 − TECs. To address this issue, we propose a enhancement strategy that utilizes a non-additive ion effect to enhance the free energy of hydrophobic ions. Specifically, the addition of strongly hydrating anions (SO 4 2− ) disrupts the coordination between weakly hydrating I 3 − ions and cations (K + ) by competitively occupying the K + coordination site. The free energy of I 3 − raise effectively and promote the hydrophobic interaction with methyl cellulose (MC), breaking the false saturation state and enabling a significantly greater ∆C. The implement of this strategy gets a high thermopower of 18.41 mV K −1 in this gel-based TECs. Moreover, a module comprising six series-connected devices produce a stable output of 520 mV under a 5 °C temperature difference. This work highlights the untapped potential of traditional systems for efficient thermal energy harvesting, offering a new strategy to overcome this false saturation state.
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产品关联
DOI
高影响因子
CHEMISTRY LETTERS
·
2016
·Vol. 45
·期 9
·1051-1053
·
IF 1.55
Wang Luanjiao,Rao Pinhua,Yao Wei,Zhang Wenqi
CuSn-codoped CdS (CdS:CuSn) quantum dots (QDs) with different Cu(I) and Sn(IV) doping levels have been successfully synthesized by a simple one-pot procedure. It was found that the doping ratio of Cu(I) and Sn(IV) in CdS QDs significantly affected the photoluminescence (PL) quantum yields (QYs), Stokes shifts, and emission window of as-prepared QDs. Compared to single Cu doping, CuSn codoping further significantly improved the PL QYs of as-prepared QDs (up to 24.6%). The CdS:CuSn QDs may be used as potential emitters in the PL industry.
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Yingying Xu,Xiali Zhang,Shengwei Yang,Jiang Liu,Yan Li,Peng Li,Guanghui Zhang,Jiao Yang,Yingchun Li
Cardiac Troponin I (cTnI), a critical biomarker for diagnosing acute myocardial infarction (AMI), plays an essential role in clinical practice. While traditional lateral flow immunoassays (LFIA) are widely used for cTnI detection due to their simplicity and rapid results, they often suffer from limited quantification capability, low sensitivity, and compromised accuracy, limiting their broader clinical application. To overcome these issues, we developed a dual-signal LFIA (dLFIA) by incorporating Au@CoO nanoparticles (NPs) for quantitative and precise cTnI determination. The synthesized Au@CoO NPs present black color as colorimetric signals and its peroxidase-like activity was adopted to yield chemiluminescence (CL) signals. It is worth noting that sodium perborate was employed to replace hydrogen peroxide as the co-reactant for the aim of enhancing long-term stability and CL intensity. Such dual-signal strategy offers self-checking merit, significantly improving detection reliability. What is more, a portable assay device was designed for automatic release of the reagents involved, further simplifying the detection process. The dLFIA demonstrated a wide linear range with limits of detection of 0.39 ng/mL in colorimetric mode and 0.22 ng/mL in chemiluminescent mode, which are 8 and 15 times more sensitive than traditional LFIA, respectively. This dLFIA platform can act as a promising assay tool for point-of-care testing, particularly in AMI diagnosis and potentially in other applications.
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DOI
高影响因子
Journal of Materials Chemistry C
·
2026
·
IF 5.1
Haocheng Huang,Qiang Lou,Hao Zhang,Xinxin Xu,Zhengjie Xu,Xuan Lu,Hang Zhou
With excellent thermal and chemical stability, tin dioxide (SnO2) has emerged as a promising electron transport layers (ETLs) for the high-efficiency n–i–p perovskite solar cells (PSCs). However, for perovskite films deposited on SnO2, the surface hydroxyl groups of SnO2 and lattice mismatch lead to severe nonradiative charge recombination at the buried interface. Moreover, the inherent brittleness of perovskite renders the buried interface mechanically more vulnerable. In this work, a dipolar π-conjugated molecule, 3,5-diaminobenzotrifluoride (CF3-mDA), is employed as a buffer layer to modify the buried interface of PSCs with a relatively wide bandgap (1.60 eV). This buffer layer effectively coarsens the perovskite grains at the buried interface, increasing the grain size from 381.50 nm to 503.47 nm, and further enhances the mechanical toughness of the buried interface and mitigates the risk of interfacial fracture. Furthermore, it passivates the defects of both SnO2 and perovskite through its functional groups, as well as induces a more favorable energy band alignment. With this buried interface modification, the champion device delivers an average power conversion efficiency (PCE) increased from 18.74% to 21.93% (22.12% under reverse scan, RS, and 21.74% under forward scan, FS), with an average open-circuit voltage (VOC) boosted from 1.188 V to 1.232 V and a significantly suppressed hysteresis. The modified devices also show a higher environmental stability than the control counterparts, maintaining an average 85.20% of their initial PCE after 16 days of storage in ambient air (with 25% relative humidity, RH, and at room temperature, RT).
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产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2026
·
IF 7.5
Shuangshuang Long,Jingwen Wang,Shuqian Meng,Yaxin Liu,Jing Zhang,Zihao Ren,Jiadi Li,Yangyang Xin,Zheng Dong,Baolu Cui,Libing Qian,Wenwu Zhou,Kai Hu,Luyao Wang,Peipei Li,Yaping Zheng,Zhiyuan Yang,Dechao Wang
Porous liquids (PLs), combine the high adsorption capacity of porous solids with the fluidity of liquids, show great promise in selective CO 2 capture. However, current studies on Type I PLs lacks systematic investigations into the regulatory role of porous host particle size and its impact on in-depth analysis of the gas sorption-separation process. Herein, we successfully fabricated PLs by grafting polyether amine oligomer chains onto the surface of size-tailored UiO-66-OH as the porous host, which endow the PLs with good thermal stability, transparency, low viscosity, and promising CO 2 /N 2 separation. UiO-66-OH-PLs were fabricated by grafting polyether amine oligomer steric solvent onto UiO-66-OH via dehydrative condensation. The effect of porous host size on CO 2 separation behavior of UiO-66-OH-PLs and the selective sorption-separation mechanism were systematically investigated using sorption isotherm and kinetic models. UiO-66-OH-PLs exhibit markedly enhanced CO 2 sorption capacity relative to the pure steric solvent, confirming the preservation of accessible cavities in porous hosts. The PLs further exhibit distinct size-dependent physicochemical and sorption properties as decreasing the particle size of UiO-66-OH porous hosts increases oligomer grafting density, reduces bulk viscosity and enhances both CO 2 sorption capacity and CO 2 /N 2 separation selectivity. CO 2 adsorption isotherms are best fitted by the SS-Langmuir-Freundlich model, indicating that CO 2 sorption by UiO-66-OH-PLs is single-component sorption on heterogeneous surfaces, integrating Langmuir monolayer sorption and Freundlich non-ideal sorption characteristics. Kinetic analysis reveals that the optimal pseudo-first-order kinetic model, demonstrating that CO 2 sorption rate is dominated by the sorption-desorption process between adsorbate molecules and adsorbent surface-active sites, rather than intraparticle or liquid film diffusion. This work opens up a promising avenue for the rational design of high-performance PLs that can be tailored to meet the demands of practical industrial chemical separation processes.
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产品关联
DOI
高影响因子
ChemSusChem
·
2026
·Vol. 19
·期 18
·e71090
·
IF 5.9
Yang-Yu Sun,Bao-Hong Xu,Yan-Xi Chen,Ya-Qi Wang,Jun-Jun Liu,Ming-Xiao Deng,Hai-Zhu Sun
Iodine (I 2 ) cathodes for aqueous Zn–I 2 batteries suffer from sluggish redox kinetics and severe polyiodide shuttling, resulting in poor utilization and cycling stability. Herein, graphitic nitrogen-enriched carbonized polymer dots (CPDs) with a core–shell structure are integrated with a self-supporting porous carbon framework to construct a graphitic nitrogen-regulated porous carbon host. The porous framework provides abundant space for iodine accommodation and accessible pathways for mass transport, while CPDs introduce graphitic-N sites that strengthen iodine–host interactions and facilitate interfacial electron transfer. Their cooperative action favors a dominant direct I 2 /I − conversion pathway with substantially suppressed accumulation of soluble polyiodide species, thereby enabling fast iodine redox kinetics and excellent cycling stability. Benefiting from these synergistic effects, the optimized PCF-CPDs/I 2 -0.2 cathode delivers a high specific capacity of 146.1 mAh g −1 at 0.3 A g −1 with 99.6% capacity retention over 500 cycles. At 1 A g −1 , it maintains 117.5 mAh g −1 with 87.1% retention after 4000 cycles. This work demonstrates that coupling porous confinement with CPDs-mediated interfacial regulation provides an effective strategy for developing high-performance Zn–I 2 batteries. Graphical Graphitic-N-enriched carbonized polymer dots (CPDs) are integrated into a self-supporting porous carbon framework (PCF) to couple porous confinement with CPDs-mediated interfacial regulation. The resulting PCF-CPDs/I 2 -0.2 cathode substantially suppresses detectable accumulation of soluble polyiodide species, favors a predominantly direct I 2 /I − conversion pathway, facilitates interfacial charge transfer, improves iodine utilization, and enables long-term cycling stability in aqueous Zn–I 2 batteries.
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DOI
高影响因子
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