ANALYTICA CHIMICA ACTA
·
2020
·
IF 5.977
Dengwang Luo,Chaoyu Zhang,Yao Fang,Yiping Shen,Yuan Liang,Yaokun Xia,Fang Wu,Xiaosong Chen,Jingrong Liu,Jinghua Chen,Chunyan Li,Jianming Lan
Phospholipase A 2 (PLA 2 ) may be a vital biomarker for the prediction and diagnosis of some diseases. Consequently, it is of great significance to quantitatively detect PLA 2 in biologic samples. Herein, on the basis of the principle of luminescence resonance energy transfer (LRET) between upconversion nanoparticles (UCNPs) and SYBR Green I (SG), we proposed a technology for the highly sensitive detection of PLA 2 amount. Therein, as an energy receptor, SG will be quantitatively loaded into liposomes firstly. Then, due to the hydrolysis of liposomes under the catalysis of PLA 2 , SG will be released and inserted into the double-stranded DNA (dsDNA) on the surface of UCNPs, which triggers the LRET because of the shortening of effective spatial distance between UCNPs and SG. Under exciting of NIR light, UCNPs emit luminescence at 476 nm, which makes SG emit fluorescence at 522 nm through LRET. Under optimal conditions, the emission intensity ratio (I 522 nm /I 476 nm ) increased linearly with the PLA 2 amount in the range of 20 U/L to 400 U/L, and the limit of detection (LOD) reached 15 U/L. Here, after comparing with the clinical standard method, it is found that the biosensor is expected to provide a convenient and sensitive assay for the detection of PLA 2 in actual serum samples. Furthermore, such biosensor can also be used to test the inhibitor of PLA 2 .
研究领域:
生物技术
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分析化学
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纳米技术
·
医学诊断
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DOI
PubMed
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2017
·
IF 2.329
Honest N.E. Kessy,Kai Wang,Lei Zhao,Molin Zhou,Zhuoyan Hu
Enzyme-assisted extraction and biotransformation of phenolic compounds from litchi pericarps were investigated. Pectinase, β-glucosidase and tannase were used individually and sequentially. The effects of various enzymes and hydrolysis conditions on recovery and biotransformation of phenolic compounds were evaluated. The results indicated that the optimum conditions for enzymatic extraction were 3% (w/w) of pectinase, 1% (w/w) of tannase and 1% (w/w) of β-glucosidase, incubation time and temperature were 180 min and 35 °C, respectively. Under these conditions, pectinase treatment was more efficient in liberating phenolic compounds compared to tannase and β-glucosidase. Sequential enzyme treatment produced more phenolic compounds than the untreated litchi pericarps. As revealed by HPLC, apart from the phenolic compounds observed in pectin and pectin–tannase treated litchi pericarps, quercetin was observed in the pectinase-β-glucosidase and pectinase-β-glucosidase-tannase treated samples, indicating that flavonols probably underwent transformation from glycosylated (rutin) to deglycosylated (quercetin) during sequential enzymatic treatments. Ferric reducing antioxidant power, DPPH radical scavenging capacity, and angiotensin I-converting enzyme inhibition capacity of the enzyme produced extracts were significantly improved compared to the untreated sample. These results suggest that enzyme-assisted produced extracts could be a promising ingredient in developing natural functional foods, and in pharmaceutical products against hypertension in humans.
研究领域:
食品科学
·
植物化学
·
药理学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Qingxin Ge,Zhou Zhou,Jing Li,Xiangyang Qu,Qiaoqiao Fang,Zhiliang Han,Rongliang Wu,Huaping Wang,Shiyan Chen
Given the widespread availability of low-grade heat (< 100 °C), its conversion into electricity represents a highly promising green technology. Thermo-electrochemical cells (TECs) have garnered significant attention for their potential in low-grade thermal energy harvesting, largely due to their relatively high thermopower. An efficient approach to achieve high thermopower is establish a high and stable concentration gradient (∆C). However, the ∆C construction process is often limited by a false saturation state in conventional I − /I 3 − TECs. To address this issue, we propose a enhancement strategy that utilizes a non-additive ion effect to enhance the free energy of hydrophobic ions. Specifically, the addition of strongly hydrating anions (SO 4 2− ) disrupts the coordination between weakly hydrating I 3 − ions and cations (K + ) by competitively occupying the K + coordination site. The free energy of I 3 − raise effectively and promote the hydrophobic interaction with methyl cellulose (MC), breaking the false saturation state and enabling a significantly greater ∆C. The implement of this strategy gets a high thermopower of 18.41 mV K −1 in this gel-based TECs. Moreover, a module comprising six series-connected devices produce a stable output of 520 mV under a 5 °C temperature difference. This work highlights the untapped potential of traditional systems for efficient thermal energy harvesting, offering a new strategy to overcome this false saturation state.
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产品关联
DOI
高影响因子
Nature Energy
·
2026
·
IF 70.1
Zhao Qiangqiang,Zhang Bingqian,Hui Wei,Gao Kun,Ji Hongpei,Sun Xiuhong,Feng Xiaopeng,Peng Cheng,Wang Kaiyu,Gao Caiyun,Zhang Chenyang,Wang Han,Zhang Qi,Su Zhenhuang,Wang Xiao,Wang Li,Pang Shuping,De Wolf Stefaan,Wang Kai
Incorporating two-dimensional (2D) perovskite phases at the interfaces of three-dimensional (3D) perovskite solar cells improves device performance. These 2D structures form in the bulk and at interfaces of the perovskite film by adding long-chain ammonium salts into the perovskite, but achieving them exclusively at the buried interface remains challenging. Here we sequentially graft thioglycolic acid and oleylamine onto SnO 2 nanoparticles. The strong chemical bond between thioglycolic acid and oleylamine ensures that cation exchange with formamidinium iodide, a perovskite precursor, occurs only during thermal annealing, creating a 2D/3D perovskite structure solely at the bottom interface. This localized 2D layer accelerates 3D phase formation, enhances perovskite crystallization and reduces defect concentration at the interface by over tenfold. The resulting solar cells achieve power conversion efficiencies of 26.19% (certified 26.04%, 0.09 cm 2 ), 23.44% (aperture area of 21.54 cm 2 , certified 22.68%) and 22.22% (aperture area of 64.80 cm 2 ), respectively.
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产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 33
·16183-16191
·
IF 3.925
Ping Ouyang,Rui Zhang,Jian Zhou,Haiyan Liu,Zhichang Liu,Chunming Xu,Shaojuan Zeng,Qian Su,Xiangping Zhang,Xianghai Meng
The effective electrochemical recovery of metal for bimetallic composite ionic liquid (IL) is related to the ion species and even the reaction mechanism under different Cu(I) contents. Thus, bimetallic composite ILs (Et3NHCl–1.54AlCl3–xCuCl, x = 0–0.23) were synthesized to investigate the Cu(I) speciation, voltammetric behavior and electrodeposition mechanism under different Cu(I) contents. For the cyclic voltammogram, three cathodic peaks of Et3NHCl–1.54AlCl3–0.010CuCl were related to the reduction of Cu(II) to Cu(I), Cu(I) to Cu(0), and Al(III) to Al(0), respectively. Meanwhile, for Et3NHCl–1.54AlCl3–0.23CuCl, the cathodic and anodic peaks were related to the redox reaction of copper. The whole offline detection of bimetallic composite ILs showed that the anodic reaction under low content of Cu(I) (≤ 0.60 wt%) was dominated by the generation of chlorine gas, while the cathodic reaction was related to the potential. However, when the Cu(I) content was higher than 2.23 wt%, only the disproportionation reaction of Cu(I) occurred and CuCl2 was obtained on the anode. Long-term electrodeposition showed that the effective recovery of copper from industrial bimetallic composite IL was realized. This study lays a good foundation for the clear understanding and comprehensive implementation of the resource utilization.
研究领域:
电化学
·
材料科学
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DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2014
·
IF 6.451
Pengjuan Ni,Yujing Sun,Haichao Dai,Jingting Hu,Shu Jiang,Yilin Wang,Zhuang Li
Glutathione (GSH) plays an important role in the biological system and serves many cellular functions. Since all of the biothiols possess similar functional groups, it is still challenging to selectively detect GSH over cysteine (Cys) and homocysteine (Hcy). In this work, a novel and simple colorimetric method for discriminative detection of glutathione (GSH) over Cys and Hcy is developed. The proposed method is based on the fact that Ag [I] ion could oxidize 3,3′,5,5′,-tetramethylbenzidine (TMB) to the oxidized TMB to induce a blue color and an absorption peak centered at 652 nm. However, the introduction of GSH could cause the reduction of oxidized TMB and it could also combine with Ag + , both of which result in a blue color fading and a decrease of the absorbance at 652 nm. Based on this finding, we propose a method to qualitatively and quantitatively detect GSH by naked eyes and UV–vis spectroscopy, respectively. The proposed method shows a low detection limit of 0.1 µM by naked eyes and 0.05 µM with the help of UV–vis spectroscopy. In addition, this method has great potential in discriminatively detecting GSH over other amino acid and biothiols. More importantly, this method is simple and fast without the preparation of nanomaterials and has also been successfully applied to the detection of GSH in biological fluids.
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DOI
高影响因子
Advanced Physics Research
·
2022
·Vol. 2
·期 4
·2200056
·
IF 0
Kuangnan Lyu,Gaochao Liu,Maxim S. Molokeev,Zhiguo Xia
Near-infrared (NIR) phosphor-converted light-emitting diodes (pc-LEDs) are desired for optoelectronic and biomedical applications, while the development of target broadband NIR phosphors still remains a significant challenge. Herein, a kind of Cr 3+ -doped AlNbO 4 phosphors with a broad NIR emission ranging from 650 to 1400 nm under 450 nm excitation are reported. A giant red-shift emission peak from 866 to 1020 nm together with broadened full width at half-maximum of 320 nm is achieved simply by varying the doped Cr 3+ concentrations. Structural and spectroscopy analysis demonstrate that a concentration-dependent site-occupation of Cr 3+ emitters in different Al 3+ sites is responsible for the tunable NIR luminescence. The as-fabricated NIR pc-LED based on optimized AlNbO 4 :Cr 3+ phosphor exhibits great potential in night-vision applications. This work provides a novel design principle on the Cr 3+ -doped AlNbO 4 phosphor with tunable broadband luminescence from NIR-I to NIR-II, and these materials can be employed in NIR spectroscopy applications.
研究领域:
光学材料
·
生物医学光学
·
光电子学
·
无机功能材料
·
分子影像
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DOI
PROCESS BIOCHEMISTRY
·
2018
·
IF 2.616
Qi Liu,Junfen Wan,Xuejun Cao
Spiramycin I is a main component of spiramycin and a structural analogue of neospiramycin I, which is an impurity in spiramycin production. Molecular imprinting technology (MIT) has many advantages in selectivity and environmental compatibility in biomolecular separation. In this study, core-shell molecularly imprinted polymers (MIPs) were prepared for spiramycin I. Methyl methacrylate (MMA) was used to prepare the seed core, and acrylamide (AM)/methacrylic acid (MAA) was chosen to prepare the shell. The structure of polymerized MIPs was successfully characterized by transmission electron microscopy, dynamic light scattering, Fourier transform infrared spectroscopy and elemental analysis. The adsorption results showed that MIPs polymerized by different monomers exhibited very different adsorption for spiramycin I. MIPs with monomeric AM achieved a fast mass transfer, high adsorption capacity and high selectivity. Then, these MIPs were applied to separate spiramycin I from the fermentation broth in the chromatographic column, and its recovery and purity were 61% and 83%, respectively. Finally, regeneration of the MIP chromatographic column was studied to explore its recycling performance in application.
研究领域:
高分子化学
·
分析化学
·
分离科学
·
制药技术
✓ 已验证
DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2023
·
IF 3.6
Qi Chen,Fang Lei,Ying Shi,Luqiao Yin,Xiaoxiao Ji,Jianjun Xie,Lei Zhang,Lingcong Fan
The all-inorganic perovskite CsPbI 3 quantum dots are difficult to achieve pure red stable luminescence due to their poor lattice thermodynamic stability and non-radiative recombination loss caused by surface halide vacancies. Therefore, the pure red perovskites are usually achieved by mixing the composition of halides (Br and I). In this work, CsPb(Br/I) 3 quantum dots (QDs) were synthesized by the hot-injection method under the synergistic effect of homophthalic acid (HA), 2-bromoethanesulphonic acid sodium salt (SBES), and oleylamine (OAm). By adjusting the molar ratio of passivates, the synergistic effect of multiple ligands can not only passivate the unliganded Pb 2+ -related defects on the surface of NCs, but also increase the formation energy of halide vacancies. Meanwhile, due to the bidentate structure of HA, smaller size of perovskites nanocrystals were obtained. Eventually, synergistic boost in device performance is achieved for color-by-blue white light-emitting diodes (WLEDs) with CIE coordinates of (0.3319, 0.3297) and have an external quantum efficiency (EQE) of 10.13%. This strategy paves an efficient way for improving the efficiency and stability of CsPb(Br/I) 3 NCs.
研究领域:
材料科学
·
纳米技术
·
光电子学
·
钙钛矿量子点
·
发光二极管（LED）
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DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2024
·
IF 3.3
Junhu Cai,Xiang Zhang,Yu Chen,Wenzong Lai,Wenyan Zhang,Zexi Lin,Yun Ye,Sheng Xu,Tailiang Guo,Jiajun Luo,Enguo Chen
Inorganic metal halide perovskite quantum dots (PQDs) have recently emerged as promising candidates for color conversion materials in Micro-LED displays, due to their outstanding color purity, high absorption coefficient, tunable emission wavelength . However the inferior stability and undesirable photoluminescence quantum yield (PLQY) restrict their particle applications. Herein, CsPbX 3 /PMMA (X = Br, I) composites with improved stability and optical performance were successfully prepared by a general and mild in-situ polymerization strategy. The ester carbonyl (C O) group in MMA formed complexes with Pb 2+ , leading to the in-situ thermal polymerization of polymethyl methacrylate (PMMA) under the action of the initiator. The multifunctional PMMA can efficiently passivate halogen vacancies while acting as a barrier against the degradation caused by heat, water, and oxygen. As a result, the PLQYs and stability of PMMA-coated CsPbX 3 PQDs have been significantly improved. When implementing CsPbX 3 /PMMA/PDMS composites as color conversion layers in Micro-LEDs, they achieve an impressive color gamut of 127.23% with excellent stability. We believe our work will stimulate the exploration of perovskite/polymer composites for industrial Micro-LED applications.
研究领域:
材料科学
·
光学工程
·
显示技术
✓ 已验证
DOI
高影响因子
INORGANICA CHIMICA ACTA
·
2026
·
IF 3.3
Karima El Mir,Hao-Yu Zhu,Juan-Juan Shao,Yu-Wen Su,Paul Kwizera,Fang-Ming Wang,Li-Zhuang Chen
Five new copper iodide complexes ( 1–5 ) were prepared by the solvent evaporation method of cuprous iodide with derivatives of 2-(1 H -imidazol-1-yl) pyrimidine ( L 1 -L 5 ). All of them are daylight white emissions among 5079–6483 K and have good thermal stabilities. Their internal quantum yields (IQYs) range from 17% to 66%. By modifying the ligand's pyrimidine ring with different groups, they successfully adjust distances of Cu…Cu in Cu 2 I 2 rhomboid dimers and further influences their optical properties, which is confirmed by electronic structure calculations employing density functional theory (DFT). This research will be very helpful for understanding the structure-activity relationship of copper (I) iodide hybrid materials. And all these complexes can be used in solid-state lighting and other optoelectronic devices.
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DOI
高影响因子
ChemSusChem
·
2026
·Vol. 19
·期 18
·e71090
·
IF 5.9
Yang-Yu Sun,Bao-Hong Xu,Yan-Xi Chen,Ya-Qi Wang,Jun-Jun Liu,Ming-Xiao Deng,Hai-Zhu Sun
Iodine (I 2 ) cathodes for aqueous Zn–I 2 batteries suffer from sluggish redox kinetics and severe polyiodide shuttling, resulting in poor utilization and cycling stability. Herein, graphitic nitrogen-enriched carbonized polymer dots (CPDs) with a core–shell structure are integrated with a self-supporting porous carbon framework to construct a graphitic nitrogen-regulated porous carbon host. The porous framework provides abundant space for iodine accommodation and accessible pathways for mass transport, while CPDs introduce graphitic-N sites that strengthen iodine–host interactions and facilitate interfacial electron transfer. Their cooperative action favors a dominant direct I 2 /I − conversion pathway with substantially suppressed accumulation of soluble polyiodide species, thereby enabling fast iodine redox kinetics and excellent cycling stability. Benefiting from these synergistic effects, the optimized PCF-CPDs/I 2 -0.2 cathode delivers a high specific capacity of 146.1 mAh g −1 at 0.3 A g −1 with 99.6% capacity retention over 500 cycles. At 1 A g −1 , it maintains 117.5 mAh g −1 with 87.1% retention after 4000 cycles. This work demonstrates that coupling porous confinement with CPDs-mediated interfacial regulation provides an effective strategy for developing high-performance Zn–I 2 batteries. Graphical Graphitic-N-enriched carbonized polymer dots (CPDs) are integrated into a self-supporting porous carbon framework (PCF) to couple porous confinement with CPDs-mediated interfacial regulation. The resulting PCF-CPDs/I 2 -0.2 cathode substantially suppresses detectable accumulation of soluble polyiodide species, favors a predominantly direct I 2 /I − conversion pathway, facilitates interfacial charge transfer, improves iodine utilization, and enables long-term cycling stability in aqueous Zn–I 2 batteries.
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DOI
高影响因子
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