MICROCHEMICAL JOURNAL
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2025
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IF 5.1
Xiaoyun Qin,Qinyuan Lou,Yiying Ling,Zhihao Zheng,Xiaomei Qin,Fenghua Chen,Jianbo Zhao,Yanghai Gui,Huishi Guo,Chao Zhao,Zhen Zhang
In the process of industrial wastewater discharge, water pollution remains a pressing challenge, with heavy metal pollution being the most critical issue. Electrochemical sensors offer advantages such as rapid response time, ease of integration with microprocessors for on-site testing. This paper proposes the use of self-assembled polystyrene (PS) microspheres as electrode modification materials, leveraging their ordered assembly structure to reduce signal differences between electrodes from different batches, thereby preparing an electrochemical sensor with good repeatability for the determination of heavy metal ions (HMIs) Cu(II), Zn(II), and Pb(II). The experiment employed square wave anodic stripping voltammetry (SWASV) to collect the stripping currents. The designed sensor exhibited sensitivities of 0.905 μA/μM, 0.408 μA/μM, and 0.264 μA/μM, as well as limits of detection (LODs) of 0.13 μM, 0.25 μM, and 0.29 μM (S/N = 3) for Cu(II), Zn(II), and Pb(II), respectively. To enhance detection accuracy, peak current, full stripping current, and feature current were respectively input combined with machine learning (ML) algorithms to construct prediction models to evaluate the performance of the sensor. The results demonstrated that the constructed RF-Feature model significantly improved detection accuracy. It demonstrated excellent reliability, with R 2 values of 0.9952, 0.9973, and 0.9976, and root mean square error (RMSE) values of 0.6580 μM, 0.5838 μM, and 0.8164 μM, for Cu(II), Zn(II), and Pb(II), respectively. The detection range was 1 μM to 70 μM. Furthermore, the effectiveness of the sensor in practical applications was validated by detection in real wastewater samples from industrial and hospital emissions. These results were validated using an inductively coupled plasma mass spectrometry (ICP-MS) method.
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JOURNAL OF NANOBIOTECHNOLOGY
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2023
·Vol. 21
·期 1
·1-19
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IF 10.2
Qiu Lei,Shen Renbin,Wei Lei,Xu Shujuan,Xia Wei,Hou Yan,Cui Jinxin,Qu Rong,Luo Jiale,Cao Jian,Yang Jie,Sun Jing,Ma Ronglin,Yu Qiang
Patients with inflammatory bowel disease (IBD) always suffer from severe abdominal pain and appear to be at high risk for colorectal cancer. Recently, the co-delivery of targeted drugs and gut microbiota has developed into an attractive strategy. A new strategy using gut microbiota fermentation to overcome the interspace diffuse resistance from the mucus layer to control drug release in inflammatory bowel sites (IBS sites) has not yet been available. Here, we designed an alginate hydrogel microsphere encapsulating bifidobacterium (Bac) and drug-modified nanoscale dietary fibers (NDFs). The hydrogel microsphere is responsible for protecting drugs from acidic and multi-enzymatic environments and delivering drugs to the colorectum. Subsequently, the fermentation of Bac by digesting NDFs and proteins as carbon and nitrogen sources can promote drug release and play a probiotic role in the gut microbiota. In vitro evidence indicated that small-sized NDF (NDF-1) could significantly promote short-chain fatty acid (SCFA) expression. Notably, NDF-1 hydrogel microspheres showed a boost release of 5-ASA in the IBS sites, resulting in the amelioration of gut inflammation and remodeling of gut microbiota in chronic colitis mice. This study developed a controlled release system based on microbial fermentation for the treatment of IBD.
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Catalysts
·
2026
·Vol. 16
·期 1
·69
·
IF 4
Lin-Yu Jiao,Ze-Long Sun,Wen-Yu Luo,Fei Wen,Jun-Bo Ye,Kang-Lai Chen,Long Xu,Bin Tian,Shan-Shan Liu
In recent years, biomass utilization has attracted extensive attention. Herein, hexagonal/cubic ZnIn2S4(ZIS) heterojunction catalysts were synthesized via a solvothermal method for the selective oxidation of 5-hydroxymethylfurfural (HMF) to 2,5-diformylfuran (DFF). The results demonstrated that the constructed heterojunctions effectively promoted carrier separation. The optimal catalyst achieved an HMF conversion rate of 88.8% and a DFF yield of 86.6% within 1 h in the open air. X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) characterizations confirmed the successful fabrication of the composite phase structure and revealed a porous spherical morphology. Equivalent circuit fitting of electrochemical impedance spectroscopy (EIS) data indicated that the hexagonal/cubic heterojunctions possessed the lowest charge transfer resistance (Rct = 5825 Ω), which effectively reduced interfacial charge transfer resistance and accelerated the transport of photoinduced carriers. Radical quenching experiments and electron paramagnetic resonance (EPR) spectroscopy identified superoxide radicals (·O2−) as the primary reactive species. Meanwhile, density functional theory (DFT) calculations elucidated the formation of the built-in electric field and the charge transfer mechanism. This work’s construction of Type-II ZIS heterojunctions effectively addressed the issue of rapid carrier recombination in pristine ZIS materials, providing a feasible strategy for biomass valorization.
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Foods
·
2025
·Vol. 14
·期 12
·2142
·
IF 5.1
Zile Wang,Dongdong Chen,Xiaomei Zheng,Yuqing Li,Shaoqian Jiang,Yanfei Chen,Jingjian Jia,Libo Yu,Tao Peng
Staphylococcus aureus(S. aureus) poses a significant threat to public health and safety, and enhancing the monitoring ofS. aureusin food is essential to curb and prevent foodborne transmission. In order to obtain strains for more convenient and rapid use in quality control or quantitative analysis, this study designed a ready-to-use “ball-in-ball” microsphere based on a novel cryoprotectant combined with drop freeze-drying technology. When using a cryoprotectant that contains 1.5% bovine serum albumin, 4.5% trehalose, 8.2% polyethylene glycol 8000, and 4.1% D-mannitol, the survival rate ofS. aureuscan reach 98.2 ± 2.6%. This cryoprotectant effectively preventsS. aureusfrom shrinking, deforming, and damaging cell walls. Additionally, it shows desirable protective efficiency for other Gram-positive bacteria. The molding of microspheres is efficient and cost-effective, demonstrating good uniformity and stability without the need for pre-freezing. The moisture content and the count ofS. aureusshowed no significant changes over 90 days at −20 °C. In the simulated contaminated sample, the recovery rate ofS. aureusin milk and green tea was 83.1–93.7%. This study could provide a practical approach to improve the monitoring efficiency ofS. aureusand shows potential as a generalized strategy for preparing ready-to-use strains related to food safety.
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ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Hongyu Dong,Panpan Tang,Xinran Wang,Ke Li,Yiwen Wang,Dong Wang,Hui Liu,Shuting Yang,Chuan Wu
Developing efficient and low-cost multifunctional electrocatalysts is important for electrochemical devices. In this work, a cost-effective Pt/NiO composite with very limited Pt loading (from 0.5 to 3%) was controllably synthesized through facile hydrothermal procedures. The composite demonstrated the improved catalytic performance as applied to the nonaqueous Li–O2 batteries and the alkaline fuel cells. Regarding the alkaline fuel cells, 1% Pt/NiO composite gave rise to the best Pt distribution and thus exhibited the optimized electrochemical conductivity and properties as suggested by the significantly improved electrochemical reversibility. Meanwhile, the demonstrated 1% Pt/NiO composite presented high catalytic capability as electrode for Li–O2 batteries, which allowed for much improved capacity utilization, high cycling stability, high initial capacity (2329 mAh/g), and no obvious voltage drop during cycling. Such multiple advantages of prepared composite electrode material offer new prospects and application as multifunctional electrocatalysts for both Li–O2 batteries and alkaline fuel cells.
研究领域:
材料科学
·
电化学
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APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Lixin Wang,Jiahao Sun,Ji'an Sun,Yuchen Yang,Yuge Wang,Ziwei Zhang,Xiyang Jin,Weiyang Lv
Layered double oxides (LDOs)-based materials have received widespread interests in advanced oxidation processes (AOPs) due to their adjustable layered structure and superior stability, while the evolution of LDOs as high-efficiency catalysts is hindered by their easy aggregation and weak conductivity. Here, we report a novel strategy to simultaneously overcome the agglomeration and poor conductivity of LDOs via calcining the mixture of polystyrene microsphere supported MgFeAl-LDH and urea, in which the introduction of hollow structure and nitrogen-doped carbon composition can not only significantly increase the specific surface area to expose more active sites, but also remarkably improve conductivity to accelerate electron transfer, giving rise to the outstanding performance of the final catalyst (HC@LDH-CN) in peroxymonosulfate (PMS) activation. Systematic characterizations and experiments further confirm that O 2 •− radicals play the dominant role in HC@LDO-CN/PMS system, which can altogether remove the model pollutant bisphenol A (BPA) in 10 min with k obs to be 0.403 min −1 . Particularly, the HC@LDO-CN still maintains extraordinary catalytic activity for BPA degradation in an extremely high-salt wastewater (100 mM). Our strategy thereby provides an innovative notion to synthesize efficient PMS-based catalysts for organic pollutant degradation in high saline water.
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CHEMICAL ENGINEERING JOURNAL
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2022
·
IF 16.744
Haiqiang Qi,Guifang Pan,Xuelin Shi,Zhirong Sun
The heterogeneous electro-Fenton (hetero-EF) technology is an attractive but challenging method used to degrade organic pollutants . The development of a catalysts for the stable and efficient degradation of pollutants under neutral conditions remains a challenging task. In this study, a microsphere catalyst consisting of magnetic Cu–Fe–FeC 3 on nitrogen-doped biochar (Cu–Fe–Fe 3 C@NDB) was prepared using chitosan as the carrier material in a two-step process. A hetero-EF system using Cu–Fe–Fe 3 C@NDB as the catalyst was constructed to efficiently degrade amoxicillin. The catalyst exhibited a wide pH application range, a good stability, and a low metal ion leaching . The main reasons behind the remarkable catalytic performance and excellent stability of the Cu–Fe–Fe 3 C@NDB catalyst are: (i) The presence of a core–shell structure, in which Cu–Fe bimetallic particles are wrapped in the structure of biomass carbon to slow down the loss of the metal active component in the catalyst and maintain its stability; (ii) The uniform dispersion of nanoparticles on the surface of the Cu–Fe–Fe 3 C@NDB catalyst, N-doped carbon, and the combined effect of Cu and Fe, which are beneficial to improve the charge transfer efficiency and regulate the electronic structure, which in turns improve the activity of the catalyst. This work demonstrates that the efficient degradation of pollutants under neutral conditions can be achieved and provides useful information for the design and synthesis of efficient and stable catalysts in hetero-EF reaction systems.
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Materials Today Communications
·
2020
·
IF 2.678
Lili Wang,Panpan Hao,Xiaomeng Chu,Yujuan Sun,Xuteng Xing,Shaojie Liu,Erjun Tang,Xiaodong Xu
With 2,2,6,6-tetramethylpiperidin-4-yl methacrylate (TMPM) and styrene (St) as monomers, the block copolymer brush of PS-PSt-PTMPM was grafted on micro-sized polystyrene microsphere via the electron transfer regenerated catalyst atom transfer radical polymerization (ARGET ATRP). The piperidine groups of PTMPM block were then oxidized to nitroxide radicals by 3-chlorobenzoic acid and PSt block was sulfonated with sulfuric acid to give the dual-functionalized block copolymer brush of PS-PSH-PTMA containing both nitroxide radicals and sulfonic acid groups. PS-PSH-PTMA was used for the direct esterification of methacrylic acid (MAA) and methoxy poly(ethylene glycol) (MPEG) for synthesis of methoxy poly(ethylene glycol) methyl acrylates (MPEGMA) instead of free acid catalyst of p-toluene sulfonic acid and free inhibitor of 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO), since the immobilized TEMPO units prevented the undesired radical self-polymerisation and the immobilized sulfonic acid residues catalyzed the esterification. The results showed that the esterification rate of MPEGMA with PS-PSH-PTMA as catalyst and inhibitor was over 99% and the reaction rate was twice as high as that with p-toluene sulfonic acid as catalyst and TEMPO as inhibitor. Furthermore, PS-PSH-PTMA could be easily recovered by filtration and the recycling performance was excellent.
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MARINE POLLUTION BULLETIN
·
2019
·
IF 3.782
Ji Yang,Zheng-Zhong Lin,Zhi-Yong Huang
A fluorescence probe was delicately designed for the detection of malachite green (MG) in water and fish samples. Through the electrostatic self-assembly of CdTe QDs on the surface of polystyrene (PS) microspheres, the fluorescence signal was amplified. After grafting molecularly imprinted film, the fluorescence probe of MIP@PS@CdTe was fabricated and applied to the detection of MG based on fluorescence quenching . The linear range of MG detection was 0.01–20 μmol L − 1 , and the detection limit was 4.7 nmol L − 1 (3 σ , n = 9) which was much lower than those of the previous reports. The recoveries of MG in aquaculture water and fish samples ranging from 87.6% to 105.4% illustrated that the detection by MIP@PS@CdTe probe was accurate and reliable.
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ANALYTICA CHIMICA ACTA
·
2023
·
IF 6.2
Meijie Ren,Yongzhen Dong,Jianlong Wang,Jianhan Lin,Lijie Qu,Yang Zhou,Yiping Chen
Aflatoxin B 1 is a carcinogenic contaminant in food or feed, and it poses a serious health risk to humans. Herein, a computer vision-assisted smartphone microscope imaging digital (SMID) immunosensor based on the click chemistry-mediated microsphere counting technology was designed for the detection of aflatoxin B 1 in peanuts. In this SMID immunosensor, the modified polystyrene (PS) microspheres were used as the signal probes and were recorded by a smartphone microscopic imaging system after immunoreaction and click chemistry reaction. The number of PS probes is adjusted by aflatoxin B 1 . The customized computer vision procedure was used to efficiently identify and count the obtained PS probes. This SMID immunosensor enables sensitive detection of aflatoxin B 1 with a linear range from 0.001 ng/mL to 500 ng/mL, providing a simple, sensitive, and portable tool for food safety supervision.
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INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2023
·
IF 5.8
Liqun Jiang,Ziyao Wang,Yan Wang,Shuo Liu,Ya Xu,Cong Zhang,Lei Li,Sujia Si,Bingmei Yao,Wenjin Dai,Huiyang Li
The re-education of tumor-associated macrophages (TAMs) is an effective strategy to inhibit the growth and metastasis of lung cancer. We have reported that chitosan could re-educate the TAMs and then inhibit cancer metastasis; however, the re-exposure of chitosan from the chemical corona on their surface is critical for this effect. In this study, a strategy was proposed to re-expose the chitosan from chemical corona, and a sustained H 2 S generation was applied to enhance the immunotherapy of chitosan. To achieve this objective, an inhalable microsphere (namely F/Fm) was designed, which could be degraded by the matrix metalloproteinase in lung cancer, releasing two kinds of nanoparticles ; in an external magnetic field, these nanoparticles can aggregate with each other, and β-cyclodextrin on the surface of one nanoparticle can be hydrolyzed by amylase on the surface of another nanoparticle, leading to the re-exposure of chitosan in the inner layer of β-cyclodextrin and the release of diallyl trisulfide for H 2 S generation. In vitro , the expression of CD86 and secretion of TNF-α by TAMs was increased by F/Fm, proving the re-education of TAMs, and the apoptosis of A549 cells was promoted with the migration and invasion being inhibited. In the Lewis lung carcinoma-bearing mouse, the F/Fm re-educated the TAMs and provided a sustained generation of H 2 S in the region of lung cancer, effectively inhibiting the growth and metastasis of lung cancer cells. This work provides a new strategy for the treatment of lung cancer in combination of re-education of TAMs by chitosan and the adjuvant chemotherapy by H 2 S.
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CERAMICS INTERNATIONAL
·
2019
·
IF 3.45
Huiqin An,Min Li,Wei Wang,Zhaotao Lv,Congying Deng,Jingyuan Huang,Zhen Yin
The novel ternary reduced graphene oxide/1D TiO 2 nanotubes/3D ZnIn 2 S 4 microspheres (rGO/TiO 2 /ZIS) heterostructured photocatalyst with high-efficiency H 2 production capacity under visible light illumination is designed and prepared in this work. In rGO/TiO 2 /ZIS system, the 1D TiO 2 nanotubes are tightly inserted in the interspace of flower-like ZnIn 2 S 4 microspheres, which are further covered by rGO, leading to an intimate contact among ZnIn 2 S 4 , TiO 2 and rGO. The exquisite design of rGO/TiO 2 /ZIS makes it possess remarkable superiority in photocatalysis . Firstly, the unique 3D microsphere structure of ZIS increases the surface area and visible light absorption ability caused by their unique hollow structure. More importantly, the matched CB and VB positions between ZIS and TiO 2 contribute to separate photogenerated holes and electrons of ZIS efficiently under visible light; then, the separated electrons on TiO 2 are further transferred to rGO due to the superior-strong electron-attracting ability of rGO. At last, the thoroughly suppressing recombination of photogenerated holes and electrons is achieved by the mutually-reinforcing synergy among ZIS, TiO 2 and rGO, and thus the hydrogen generation capacity of ZIS is significantly enhanced. The H 2 production amount and rate of rGO/TiO 2 /ZIS (2.0 wt% rGO and 50 wt% ZIS) after 10 h are 4623 μmol/g and 462.3 μmol/g/h, respectively, which is 71.1 times of pristine TiO 2 and 1.6 times of ZIS under the same condition. The apparent quantum yield of rGO/TiO 2 /ZIS (2.0 wt% rGO and 50 wt% ZIS) in 10 h is about 0.6888%. This excellent photocatalytic performance is ascribed to the mutually-reinforcing synergy among ZIS, TiO 2 and rGO, which can be confirmed by X-ray photoelectron spectroscopy, photoelectrochemical measurements and photoluminescence spectrum. Based on the photocatalytic and characterization results, the corresponding mechanism is proposed.
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