INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
·
IF 8.2
Weijie Lin,Shuai Wu,Shibo Han,Jie Xie,Hongshen He,Qiuxia Zou,Dezhong Xu,Dengwen Ning,Ajoy Kanti Mondal,Fang Huang
The highly conductive and elastic three-dimensional mesh porous material is an ideal platform for the fabrication of high electrical conductivity conductive aerogels. Herein, a multifunctional aerogel that is lightweight, highly conductive and stable sensing properties is reported. Tunicate nanocellulose (TCNCs) with a high aspect ratio, high Young's modulus , high crystallinity, good biocompatibility and biodegradability was used as the basic skeleton to prepare aerogel by freeze-drying technique. Alkali lignin (AL) was used as the raw material, polyethylene glycol diglycidyl ether (PEGDGE) was used as the cross-linking agent, and polyaniline (PANI) was used as the conductive polymer. Preparation of aerogels by freeze-drying technique, in situ synthesis of PANI, and construction of highly conductive aerogel from lignin/TCNCs. The structure, morphology and crystallinity of the aerogel were characterized by FT-IR, SEM, and XRD. The results show that the aerogel has good conductivity (as high as 5.41 S/m) and excellent sensing performance. When the aerogel was assembled as a supercapacitor, the maximum specific capacitance can reach 772 mF/cm 2 at 1 mA/cm 2 current density, and maximum power and energy density can reach 59.4 μWh/cm 2 and 3600 μW/cm 2 , respectively. It is expected the aerogel can be applied in the field of wearable devices and electronic skin.
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Catalysts
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2023
·Vol. 13
·期 5
·878
·
IF 3.9
Yue Huang,Renhao Si,Yi Wei
Lignin is a crucial raw material for the synthesis of phenol due to its high oxygen concentration; however, the selectivity of phenol in pyrolysis products is low. This study chose cerium oxide as the coupling agent for molten salts, and the reaction’s process conditions—including temperature and catalyst dosage—were examined. The influence of metal loading on the reaction and byproducts of catalytic pyrolysis was examined. The outcomes demonstrated that the best monophenol production was accomplished at 550 °C and an Fe loading of 15 wt.%, with 93.93 wt.% monophenols in the bio-oil. While methoxy was more easily broken and rearranged, producing more monophenols, the presence of the catalyst enhanced the oxidation of Cα-OH and the breaking of β-O-4 bonds, which is significant for the study of lignin pyrolysis.Keywords:molten carbonates;pyrolysis;deoxidation;monophenols;lignin
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INDUSTRIAL CROPS AND PRODUCTS
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2023
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IF 5.9
Fuyuan Lu,Shuzhen Ni,Xiangxi Meng,Chuanling Si,Menghua Qin,Yan Wang,Yingjuan Fu,Xiaoqian Chen
The majority of current oral drugs are hydrophobic, and have the toxic side effects to the gastrointestinal tract, which limit their therapeutic efficacy. In order to improve the performance of drug formulations, the development of new functional materials is crucial for the technological breakthroughs in the pharmaceutical industry. The antimicrobial and antioxidant properties of lignin nanoparticles (LNPs) give them great potential for application in this field. LNPs consist of a hydrophilic shell and hydrophobic core, which is particularly suitable for the capsulation of hydrophobic drugs, and then it would increase the stability and solubility of drugs and reduced the irritation to the stomach. In this study, alkali lignin (AL) was fractionated by 80% methanol to obtain targeted MAL with low molecular weight, high phenolic hydroxyl content and good homogeneity. The LNPs was prepared by quaternization modification of MAL and self-assembling in an ethanol/water mixture. Their application in the hydrophobic oral drug delivery system was evaluated and Ibuprofen (IBU) was used as a drug pattern. The effect of solvent exchange time (24 h, 36 h, 48 h and 60 h) on the formation process of IBU-loaded LNPs (IBU-LNPs) was investigated. The in vitro release experiments were conducted and it revealed that IBU release occurred priority in the intestine rather than the stomach, which were meeting the release requirements of ideal oral carrier. In addition, IBU-LNPs showed non-cytotoxic against the L929 cells and improved the bioavailability of IBU drugs. Therefore, this work proposes a preparation method of the smart lignin nanoparticle by screening characteristic lignin with higher reactivity and by modulating the solvent exchange time during the preparation process. Overall, LNPs showed the great potential of application in pharmaceuticals industry and was demonstrated a promising and green product.
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FOOD CHEMISTRY
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2023
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IF 8.8
Yanchao Liu,Min Zheng
Foodborne pathogens seriously endanger people's health and cause significant economic losses. Therefore, it is of great significance to design potent packaging materials with the function of alleviating food spoiling and extending shelf life. Here, three BODIPY derivatives (named as N-BDPI, B-BDPI and P-BDPI) were synthesized by substituting the 8-position of BODIPY with naphthalene, biphenyl and pyridine groups, respectively, and their photophysical properties as well as antibacterial capacities were characterized. The results demonstrated that N-BDPI had the best singlet oxygen generation ability and could completely kill S. aureus under light irradiation with the minimum inhibitory concentration of only 50 nmol/L. In addition, 1.0% [email protected] /AL composite film was fabricated by doping N-BDPI into polyvinyl alcohol (PVA) and alkaline lignin (AL) exhibited high antibacterial activity on Gram-positive bacteria. The coating of strawberries with 1.0% [email protected] /AL film not only effectively inhibited the mildew of strawberries, but also extended their shelf life.
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BIORESOURCE TECHNOLOGY
·
2023
·
IF 11.4
Qi Li,Ruiying Gao,Yucheng Li,Bo Fan,Cuiluan Ma,Yu-Cai He
Lignin is a critical biopolymer for creating a large number of highly valuable biobased compounds. Vanillin, one of lignin-derived aromatics, can be used to synthesize vanillylamine that is a key fine chemical and pharmaceutical intermediate. To produce vanillylamine, a productive whole-cell-catalyzed biotransformation of vanillin was developed in deep eutectic solvent − surfactant − H 2 O media. One newly created recombinant E. coli 30CA cells expressing ω-transaminase and L -alanine dehydrogenase was employed to transform 50 mM and 60 mM vanillin into vanillylamine in the yield of 82.2% and 8.5% under 40 °C, respectively. The biotransamination efficiency was enhanced by introducing surfactant PEG-2000 (40 mM) and deep eutectic solvent ChCl:LA (5.0 wt%, pH 8.0), and the highest vanillylamine yield reached 90.0% from 60 mM vanillin. Building an effective bioprocess was utilized for transamination of lignin-derived vanillin to vanillylamine with newly created bacteria in an eco-friendly medium, which had potential application for valorization of lignin to value-added compounds.
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Polymers
·
2023
·Vol. 15
·期 8
·1947
·
IF 5
Linfei Zhou,Xiangyu You,Lingjie Wang,Shijie Qi,Ruichen Wang,Yasumitsu Uraki,Huijie Zhang
Lignin-based carbon fibers (LCFs) with graphitized structures decorated on their surfaces were successfully prepared using the simultaneous catalyst loading and chemical stabilization of melt-spun lignin fibers, followed by quick carbonization functionalized as catalytic graphitization. This technique not only enables surficial graphitized LCF preparation at a relatively low temperature of 1200 °C but also avoids additional treatments used in conventional carbon fiber production. The LCFs were then used as electrode materials in a supercapacitor assembly. Electrochemical measurements confirmed that LCF-0.4, a sample with a relatively low specific surface area of 89.9 m2g−1, exhibited the best electrochemical properties. The supercapacitor with LCF-0.4 had a specific capacitance of 10.7 F g−1at 0.5 A g−1, a power density of 869.5 W kg−1, an energy density of 15.7 Wh kg−1, and a capacitance retention of 100% after 1500 cycles, even without activation.Keywords:lignin;carbon fiber;catalytic graphitization;supercapacitor;electrochemical performance
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CATALYSIS COMMUNICATIONS
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2023
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IF 3.7
Zhouqi Tian,Yongmig Zeng,Hongmei Zhao,Jing Yang,Hongxi Zhang
Rare earth catalysts have gained considerable attention in the catalytic depolymerization of lignin. However, their structure-performance relationship was rarely reported. This work demonstrated that the different morphologies of Sm 2 O 3 exhibited remarkable structure-activity relationships in the catalytic oxidation of lignin. Four different morphologies of samarium oxides, namely rod-like, tube-like, octahedral, and multilayer were investigated. Rod-like Sm 2 O 3 catalyst exhibited optimum activity in the oxidation of lignin model molecules and real lignin. The {222} crystal surface of the Sm 2 O 3 catalyst was proved to play a key role. β-O-4, C α -C β , and C sp2 -C sp2 chemical bonds in lignin were synchronously broken.
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ACS Applied Bio Materials
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2023
·
IF 4.7
Yeyan Chao,Shengkai Yu,Hua Zhang,Dirong Gong,Jingrui Li,Fan Wang,Jing Chen,Jin Zhu,Jing Chen
With the development of antimicrobial resistance, rapid and effective killing of bacteria is required for infected wound healing after skin trauma. Herein, we reported a one-pot reaction strategy to prepare a composite hydrogel with antibacterial activity through high-efficiency photothermal therapy. We take poly(vinyl alcohol) as the matrix, and lignin-derived from biomass was introduced into the hydrogel to increase the tensile strength of the prepared hydrogel to 108.58 kPa, and the elongation at break reaches 200.8%. The electrostatic interaction between lignin and chitosan enhanced the reactivity of lignin. Carbon nanotubes endow the hydrogel with photothermal antibacterial activity that can kill more than 97% of either Escherichia coli or Staphylococcus aureus within 5 min, avoiding the problem of bacterial resistance. Experimental evaluation on mice showed that the hydrogel could effectively promote wound healing of full-thickness skin defects. The hydrogels with good mechanical properties, antioxidant activity, and excellent photothermal antibacterial ability show good potential to repair the damaged tissue and are expected to be used in the clinical transformation of wound dressing.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2023
·
IF 8.6
Wei Wu,Yingying Zhao,Junjie Qi,Chunli Li,Jing Fang,Boyang Xu,Gaojin Lyu,Gang Li,Hao Li
The synthesis and application of conventional polymeric flocculants suffer from low flocculation efficiency and toxic residues; therefore, there is an urgent need to develop green and efficient flocculants and corresponding technologies. An amphiphilic copolymer (NPL) was synthesized by a “grafting to” strategy, using acrylamide, 3-chloro-2-hydroxypropyltrimethylammonium chloride, and kraft lignin. NPL consists of a lignin core that is attached to a polyacrylamide branched chain and a cationic group, and has the properties of an amphoteric polyelectrolyte . This structure demonstrates superior flocculation performance on suspended solids. Two typical clay suspensions, kaolin and bentonite, were selected to evaluate the flocculation performance of NPL. The results showed that the turbidity of kaolin and bentonite could be reduced to 2.08 NTU and 0.31 NTU, respectively, by using NPL in combination with polymeric aluminum chloride. The synergistic effect of charge neutralization and bridging was confirmed as the main mechanism of flocculation on the two clay suspensions by a series of characterization techniques, such as zeta potential determination, particle size analysis , and focused beam reflectance measurement. The treatment of high-turbidity wastewater/feedwater with NPL was investigated, and was found to significantly improve the effluent quality. The use of NPL is efficient, environmentally friendly, and technically feasible, and shows excellent potential for the treatment of wastewater.
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BIOMACROMOLECULES
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2023
·
IF 6.2
Shuang Qi,Bo Jiang,Caoxing Huang,Yongcan Jin
With the rapid increase of diabetes cases in the world, there is an increasing demand for slowing down and managing diabetes and its effects. It is considered that a viable prophylactic treatment for type 2 diabetes mellitus (T2DM) is to reduce carbohydrate digestibility by controlling the activities of α-amylase and α-glucosidase to control postprandial hyperglycemia and promote the growth of intestinal beneficial bacteria. In this work, the effects of sulfonated lignin with different sulfonation degrees (0.8 mmol/g, SL1; 2.9 mmol/g, SL2) on the inhibition of α-amylase and α-glucosidase and the proliferation of intestinal beneficial bacteria in vitro were investigated. The results showed that both SL1 and SL2 can inhibit the activity of α-amylase and α-glucosidase. The inhibition capacity (IC50, 32.35 μg/mL) of SL2 with a low concentration (0–0.5 mg/mL) to α-amylase was close to that of acarbose to α-amylase (IC50, 27.33 μg/mL). Compared with the control groups, the bacterial cell concentrations of Bifidobacteria adolescentis and Lactobacillus acidophilus cultured with SL1 and SL2 increased in varying degrees (8–36%), and the produced short-chain fatty acids were about 1.2 times higher. This work demonstrates the prospect of sulfonated lignin as a prebiotic for the prevention and treatment of T2DM, which provides new insights for opening up a brand new field of lignin.
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ENVIRONMENTAL MICROBIOLOGY
·
2019
·Vol. 21
·期 5
·1847-1863
·
IF 5.147
Lu Lin,Xiaopeng Wang,Lanfang Cao,Meiying Xu
Summary Lignin is one of the largest carbon reservoirs in the environment, playing an important role in the global carbon cycle. However, lignin degradation in bacteria, especially non-model organisms, has not been well characterized either enzymatically or genetically. Here, a lignin-degrading bacterial strain, Pseudomonas putida A514, was used as the research model. Genomic and proteomic analyses suggested that two B subfamily dye-decolorizing peroxidases (DypBs) were prominent in lignin depolymerization, while the classic O 2 -dependent ring cleavage strategy was utilized in central pathways to catabolize lignin-derived aromatic compounds that were funnelled by peripheral pathways. These enzymes, together with a range of transporters, sequential and expression-dose dependent regulation and stress response systems coordinated for lignin metabolism. Catalytic assays indicated these DypBs show unique Mn 2+ independent lignin depolymerization activity, while Mn 2+ oxidation activity is absent. Furthermore, a high synergy between DypB enzymes and A514 cells was observed to promote cell growth (5 × 10 12 cfus/ml) and lignin degradation (27%). This suggested DypBs are competitive lignin biocatalysts and pinpointed limited extracellular secretion capacity as the rate-limiting factor in bacterial lignin degradation. DypB production was, therefore, optimized in recombinant strains and a 14,141-fold increase in DypB activity (56,565 U/l) was achieved, providing novel insights for lignin bioconversion.
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ENERGY & FUELS
·
2019
·
IF 3.021
Zhiguo Dong,Haiping Yang,Peiao Chen,Zihao Liu,Yingquan Chen,Lei Wang,Xianhua Wang,Hanping Chen
In this study, the chemical structure of corn straw lignin and the catalytic pyrolysis behavior at 350–650 °C in a fixed bed was investigated, with TiO2-based catalysts (load Cu, Fe, and Mo) respective to phenolic compounds production. It was found that β-O-4 is the most frequent linkage in corn straw lignin, up to 89%. The highest selectivity (79%) and yield (21.17 mg/(g lignin)) of phenols was obtained at 450 °C for lignin pyrolysis. TiO2 addition enhanced the production of bio-oil with more phenols formed, and the selectivity of phenols reached 86%, with the yield up to 23.64 mg/(g lignin). With Cu or Fe loading, the yield and selectivity of phenols decreased, but the content of aromatic ketones increased obviously. But with Mo addition, the yield and selectivity of phenols increased apparently to 26.72 mg/(g lignin) and 89%, respectively, especially for monophenols and guaiacols. This suggests that the thermal catalytic activity of TiO2 can be further improved by doping a specific metal.
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