Biology-Basel
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2025
·Vol. 14
·期 11
·1498
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IF 3.5
Senyue Liu,Yang Feng,Zhipeng Huang,Chengyan Mou,Qiang Li,Yongqiang Deng
Simple SummaryIn 2024 summer, the endangered Yangtze sturgeon in China suffered large-scale deaths, which was an urgent problem to solve. This study aimed to identify the cause of the disease and provide a basis for protecting the Yangtze sturgeon and preventing such diseases. The findings revealed that the bacterial co-infection (Streptococcus iniae, Klebsiella pneumoniae, Edwardsiella tarda, and Bacillus cereus) triggered by high temperature and high humidity environmental stress was closely related to this large-scale death event. And these bacteria all exhibited resistance to commonly used antibiotics in aquaculture. This was the first time multiple bacterial co-infection was found in Yangtze sturgeon, so protection should shift from focusing on a single bacterium to multiple ones, and ecological prevention measures are needed. These findings help protect this rare species, guide disease prevention in aquaculture, and safeguard aquatic ecological security.The Yangtze sturgeon (Acipenser dabryanus) is designated as critically endangered in the IUCN Red List and is a first-class protected species in China. During the summer of 2024, it suffered lethal disease outbreaks. Comprehensive pathological and microbiological analyses were conducted to clarify the etiology. Clinically, infected sturgeon exhibited systemic manifestations including cutaneous ulcers, hemorrhagic septicemia, and diffuse necrosis in liver, kidney and heart tissues. Histopathologically, infected sturgeon showed liver hepatocyte vacuolation/necrosis, renal glomerular atrophy, and cardiac epicardial thickening with lymphocyte/eosinophil infiltration; Gram staining revealed co-localized Gram-positive/negative bacteria in lesions, and TEM identified diverse bacterial morphotypes. Through isolation and molecular identification, four bacterial pathogens were characterized:Streptococcus iniae,Klebsiella pneumoniae,Edwardsiella tarda, andBacillus cereus.Bacterial load detection revealed the presence of these pathogens in lesion tissues. Antimicrobial susceptibility testing indicated multidrug resistance to florfenicol, tetracycline, and ampicillin (commonly used antibiotics in aquaculture), while high sensitivity to ceftazidime, ceftriaxone, and ciprofloxacin was observed. Thus, we infer that sustained high-temperature stress triggered bacterial co-infection is closely related to this large-scale death incident. This is the first evidence of polymicrobial infection in the Yangtze sturgeon, emphasizing the significance of shifting from a single-pathogen perspective to a multi-pathogen framework, and highlighting the urgency of implementing ecological prevention strategies for this species.
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JOURNAL OF MATERIALS SCIENCE
·
2026
·
IF 3.9
Li Qingqing,Liu Yufeng,Zhu Tianyu,Xu Defeng,Hu Hang
Breast cancer stands as the most prevalent type of cancer globally and the leading cause of cancer-related deaths among women. Owing to the substantial side effects associated with conventional treatments such as chemotherapy and radiotherapy, drug delivery systems have been proposed to co-deliver drugs with varying physicochemical properties to tumor cells, thereby achieving a synergistic therapeutic effect. Herein, we designed novel liposomes by membrane hydration method to co-deliver crocetin (CRO) and the chemotherapeutic drug docetaxel (DTX) for the treatment of breast cancer in order to potentiate the efficacy of chemotherapy. The prepared DTX-CRO liposomes (DTX-CRO-Lip) were characterized by transmission electron microscopy (TEM) and dynamic light scattering analysis. DTX-CRO-Lip showed homogeneous spherical morphology and the mean particle size of 75.35 ± 0.52 nm, polydispersity index of 0.26 ± 0.01, and zeta potential of -0.16 ± 0.19 mV. The in vitro drug release study and MTT assays showed that DTX-CRO-Lip had sustained drug release effects and synergistic antitumor effect. The in vivo antitumor efficacy was verified on 4T1 tumor-bearing mice. DTX-CRO-Lip showed the best antitumor efficacy and no apparent side effects, suggesting that it is a promising drug delivery system for the synergistic treatment of breast cancer.
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JOURNAL OF SOLID STATE CHEMISTRY
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2019
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IF 2.291
Li Wang,Danni Shao,Jianyu Guo,Siyong Zhang,Yan Lu
In this paper, a new porous Co-coordination polymer, with the merits of high specific surface areas and high nitrogen content, is synthesized as the electrode material to enhance the electrical performance of supercapacitor . Its electrochemical performance is investigated in the electrolyte of 3 M KOH. The nitrogen doping Co-coordination polymer product at 140 °C exhibits the highest specific capacitance of 512 F g -1 at a current density of 1 A g -1 . Excellent cycle performance is observed. The capacitance value remains 97.4% even after 40000 cycles. More significantly, the Co-coordination polymer exhibits the energy density of 13.27 Wh kg -1 at a power density of 2913 W kg -1 .
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ENERGY & FUELS
·
2023
·
IF 5.3
Guolin Cao,Zhuomin Jin,Yuebing Dong,Qiyong Shi
LiNi0.8Co0.1Mn0.1O2 (NCM811) is considered a cathode material with great commercial potential. However, Li/Ni mixing, residual lithium compounds, and side reaction limited the popularity of Ni-rich batteries. Thus, a simple strategy is employed to realize a comodification of Na+ and Y3+. As demonstrated in the XPS results, the residual lithium compounds (Li2CO3/LiOH) and side reaction products are inhibited. The capacity retention rate of the modified NCM811 is 86.4% after 300 cycles at 1C, 34.5% higher than that of the pristine. Na+ expands the space of the Li+ slab, thereby reducing the charge transfer resistance and inhibiting the mixed discharge of cations. Meanwhile, Y3+ decreased the lattice along c-axis to restrict the movement of cations (Ni2+) into the Li site, with improving the exchange of Li+. The formed LiYO2 coating layer restrains the direct contact between the electrolyte and the electrode material so that side reactions are inhibited, reducing the electrochemical resistance.
研究领域:
材料科学
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电化学
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储能技术
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锂离子电池
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ACS Applied Materials & Interfaces
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2012
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IF 4.525
Jiantao Lin,Caihong Li,Yi Zhao,Jianchan Hu,Li-Ming Zhang
To develop biocompatible nanofibrous membranes for wound healing, we investigated the coelectrospinning of two proteins (collagen and zein) in aqueous acetic acid solution. It was found that the combination of zein could improve the electrospinnability of collagen. For the resultant electrospun membrane, its fiber diameter, surface wettability, mechanical, and in vitro degradable properties as well as cell adhesive ability could be modulated by the change of collagen/zein blending ratio. Moreover, berberine drug could be incorporated in situ into the electrospun nanofibrous membrane for its controlled release and antibacterial activity. The addition of berberine showed little effects on the fiber morphology and cell viability. In addition, the wound healing performance of the as-obtained nanofibrous membranes was examined in vivo by using female Sprague–Dawley rats and histological observation.
研究领域:
生物医学工程
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组织工程
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药物递送
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纳米技术
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伤口护理
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JOURNAL OF ALLOYS AND COMPOUNDS
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2022
·
IF 6.371
Lei Wang,Xudong Liu,Mu Zhang,Xiaoguo Bi,Zhixin Ma,Jinsheng Li,Jialin Chen,Xudong Sun
(Nb 0.5 Ga 0.5 ) x Ti 1−x O 2 (x = 0.05%,0.2%,0.5%,1%,5%) single crystals were prepared by Verneuil method. Even if the doping amount is 0.05%, the dielectric permittivity (ε′) is obviously higher than that of pure rutile TiO 2 (260), reaching more than 10 4 . As the doping amount x increase, the ε′ increases, and reaches the maximum value when x = 5%, but the dielectric loss increases correspondingly. The best dielectric performance (ε′=1.0 ×10 5 , tanδ=0.034 under 1 kHz) is obtained when the doping amount is 0.5%. Even at 10 6 Hz, the dielectric loss is only 0.019, much lower than the reported ceramic samples. This may be due to the fact crystalline materials can effectively reduce defects such as grain boundary, second phase, porosity and segregation. The dielectric spectra, impedance analysis, XPS and DC bias results show that the colossal permittivity (CP) properties could be attributed to EPDD polarization. With the increase of doping concentration (>1%), the hopping polarization occurs, resulting in a slight increase in dielectric loss. These results indicate that TiO 2 crystal materials with lower dielectric loss are good candidates for dielectric materials. Taking TiO 2 crystal as the research object, we can have a clearer understanding of the origin of TiO 2 dielectric properties and the influence of doping ion content, which is of great significance to the development of TiO 2 -based dielectric materials.
研究领域:
材料科学
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介电材料
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晶体生长
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固体物理
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Energy Sources Part A-Recovery Utilization and Environmental Effects
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2016
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IF 0.455
Baoxia Li,Wenjuan Wei
In order to investigate the role of the lignin in the co-pyrolysis process of the sludge and the cellulose, the co-pyrolysis process was carried out in a thermogravimetry analyzer. The result shows that when the proportion of the sludge:cellulose:lignin was 1:1:0.4, the main co-pyrolysis temperature range was narrower, the ultimate pyrolysis weight loss was more, and the synergistic effect had a longer duration time. When the pyrolysis temperature was below 400°C, the addition of the lignin could promote the co-pyrolysis process of the cellulose and the sludge, such as the decrease of the activation energy E.
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Acta Crystallographica Section B-Structural Science Crystal Engineering and Materials
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2026
·Vol. 82
·期 2
·
IF 2.5
Liang J.-F.,Wang Y.-T.,Xie M.,Li D.
Single-crystal X-ray diffraction is one of the most reliable techniques for elucidating the molecular structures, while it requires high-quality single crystals. The crystalline mate (CM) strategy has recently emerged as an effective method to induce rapid and selective co-crystallization. Here, we demonstrate that this strategy can be reliably extended to ionic systems using the neutral trinuclear silver pyrazolate complex Ag3Pz3 as a crystallization mate. By regulating solvent polarity, two co-crystals of silver pyrazolate berberine hydrochloride Ag3Pz3·BCl, SF (sandwich form) and NSF (non-sandwiched form), were obtained. In SF, neutral Ag3Pz3 simultaneously engages the Cl− anion via π-acid/base contacts and the berberine cation through weak Ag⋯O coordination. Remarkably, SF can also be crystallized directly from crude Coptis chinensis extract without prior purification. In NSF, due to the influence from methanol or ethanol, Ag3Pz3 rearranges into a rare anionic Ag3Pz4 cluster that serves as the counterion to berberine. These results establish solvent polarity as a decisive factor governing CM-mediated co-crystal assembly and broaden the applicability of the crystalline-mate concept to ionic systems.
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JOURNAL OF ENVIRONMENTAL MANAGEMENT
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2026
·
IF 9.2
Mingda Hua,Yang Cao,Meilan Zhang,Haiyan Zhou,Shicheng Zhang
As a hazardous pollutant, ammonia (NH 3 ) poses significant environmental and health risks. This study synthesized multifunctional NH 3 -adsorption biochar through co-pyrolysis of food waste digestate (FWD) and wood waste (WW), focusing on the physicochemical properties of derived biochar and their contributions to NH 3 adsorption. The optimized conditions enabled biochar with tunable production yields (25.8-67.9 wt%) and enhanced porosity (specific surface area reaching up to 331 m 2 /g). Thermogravimetric mass spectrometry combined with multiple spectral analyses uncovered a three-stage devolatilization process and tracked the structural transformations of the resultant biochar. Additionally, acid washing was applied to selectively remove surface-bound metallic salts from high-ash-content FWD-WW co-pyrolysis biochar, thereby liberating more active sites. Langmuir and Freundlich adsorption equilibrium models were systematically applied to evaluate the NH 3 adsorption performance of the biochar with/without modification, revealing a maximum adsorption capacity of 124.2 mg/g at 25 °C (1 bar). Adsorption kinetics and thermodynamics indicated that NH 3 adsorption occurred predominantly via spontaneous physisorption, enhanced by chemisorption at Brønsted acid sites (-COOH/Si-OH) and Lewis acid sites (Fe 3+ /Al 3+ ). This study demonstrates a waste-to-adsorbent strategy through controlled co-pyrolysis and surface engineering for sustainable air pollution mitigation.
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ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19.9
Danyang Ren,Yuqi Wang,Da Gao,Liubing Dong,Shaobo Wang,Xuanhao Wang,Yuqian Meng,Ruimin Chen,Chiye Li,Junhui Shi,Yonggang Yin
The proliferation of distributed Internet of Things (IoT) nodes and wearable electronics demands sustainable, high-performance power sources capable of harvesting ambient mechanical energy. However, current piezoelectric energy harvesters (PEHs) face a critical efficiency–mechanics–sustainability trilemma. Here, we report a fully water-processed, bio-derived piezocomposite that overcomes these limitations by coupling Schottky-type interfacial electronic engineering with a dynamically hydrogen-bonded molecular network. We demonstrate that in situ synthesized copper–piezoceramic (Cu@KNN; KNN, (Na 0.5 K 0.5 )NbO 3 ) Schottky-type interfaces introduce built-in electric fields to actively regulate charge transport, thereby suppressing polarization screening and intensifying local field distribution to maximize polarization efficiency and the piezoelectric response—a fundamental departure from traditional passive dielectric tuning. Concurrently, we engineer a cellulose matrix where small-molecule modifiers (glucose and urea) reorganize the rigid structure into a dynamic network that accommodates deformation through reversible hydrogen-bond breaking and reformation. The resulting harvester exhibits exceptional stretchability (up to 269% strain) and durability (>8000 cycles), delivering a high pressure sensitivity of 1.67 V kPa −1 and an instantaneous power output of ∼940 µW—sufficient to directly power commercial electronics and charge energy storage units. This work establishes a scalable, eco-friendly paradigm for designing mechanically adaptive energy harvesters, paving the way for sustainable, self-powered bio-integrated electronics.
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ACS Catalysis
·
2026
·
IF 13.6
Jieting He,Ying Tao,Yu Liang,Liang Zhao,Xiaoyang Jerry Huang,Rena Oh,Shi-Gang Sun,Lei Liu,Jinxiang Dong
Hydrogenation of aromatic compounds under mild conditions remains challenging because of the high stability of aromatic π systems. Here, we report a physically mixed catalyst comprising rhodium (Rh) and cobalt (Co) nanoparticles embedded in montmorillonite (MMT) that overcomes this limitation. The enhanced activity arises from dynamic interparticle cooperation: Rh nanoparticles selectively dissociate H2, and the resulting hydrogen intermediates are transferred through particle collisions to Co nanoparticles, where aromatic hydrogenation occurs. This cooperative process can be finely regulated by tuning the oxidation states of the individual metal nanoparticles, leading to catalytic performance surpassing that of corresponding Rh−Co alloy catalysts (initial rate: 45 vs 9 μM s-1). Combined experimental and computational investigations reveal that cooperative catalysis can be quantitatively described using linear regression analysis and thereby be predicted through the rate ∼k × (Co2+/Co3+)/(Rh0/Rh3+). Our findings establish a data-driven statistical approach for designing high-performance bimetallic catalysts based on dynamic interparticle interactions.
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Journal of Physical Chemistry C
·
2026
·
IF 3.4
Zhilin Yang,Weimin Huang,Hua Yang
To address the issues of energy depletion and environmental pollution caused by the combustion of fossil fuels, electrocatalytic overall water splitting for hydrogen production is one of the very promising approaches. The key to the large-scale application of electrocatalytic overall water splitting lies in the search for low-cost, high-content, and high-performance electrocatalysts. In this paper, through a two-step process of carbonization followed by phosphination, the P-modified Co2C@Co/NF composite material (P–Co2C@Co/NF) was successfully designed and synthesized. P–Co2C@Co/NF exhibits excellent performance in hydrogen evolution reactions (HER) and oxygen evolution reactions (OER). Under alkaline conditions, the overpotential for HER and OER can reach 10 mA cm–2 current density with only 75 mV and 246 mV respectively. P–Co2C@Co/NF demonstrates excellent overall water splitting capability, requiring only 1.63 V of driving voltage to achieve 10 current density. This provides a new method for enhancing the electrocatalytic performance of heteroatom-modified transition metal compounds.
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