Inorganic Chemistry Frontiers
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2022
·Vol. 9
·期 14
·3590-3597
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IF 7.779
Qiang Wang,Wen Song,Yang Lan,Liling Cao,Ling Huang,Daojiang Gao,Jian Bi,Guohong Zou
KBe2BO3F2 (KBBF) with a perfect honeycomb hexagonal layered structure is the sole practical deep-ultraviolet (DUV) nonlinear optical material which could generate DUV coherent light through direct frequency doubling. However, the layered growth habit and the toxicity of Be severely hinder its extensive applications. Herein, a non-centrosymmetric fluoride carbonate, KLi2CO3F, was successfully developed via chemical co-substitution with KBBF as the prototype. KLi2CO3F preserves the structural merits of KBBF, containing neatly arranged infinite planar [Li2CO3F2]∞ layers. In particular, compared with the weak interlayer K–F electrostatic attraction in KBBF, KLi2CO3F presents a stronger interlayer binding energy induced by the shorter and stronger Li–F bonds, which effectively overcomes the layered tendency of crystal growth. Simultaneously, KLi2CO3F exhibits a large birefringence of approximately 0.102@546 nm and a short ultraviolet absorption edge down to 190 nm, indicating that it is a promising DUV birefringent material.
研究领域:
材料科学
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光学
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晶体学
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DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2022
·
IF 4.326
Mengchen Li,Zhiyu Zhu,Junteng Liu,Junsu Jin,Le Du,Jianguo Mi
A macroporous organic adsorbent was designed and prepared using the template method, with acrylamide (AM) as the skeleton, glycidyl methacrylate (GMA) as the shell, and F-127 and Pluronic block copolymer (P123) as surfactants, and grafted with polyethyleneimine (PEI). Solid adsorbents were used for carbon dioxide capture. The effect of the AM/GMA mass ratio on the spherical morphology, through-hole structure, specific surface area, hardness, hydrophobicity, and thermal stability was comprehensively investigated, and the CO2 adsorption performance of the PEI-modified adsorbent was studied. Surface area and morphology characterization showed that after the introduction of GMA, the wall thickness and roughness increased, and the specific surface area and the mass of GMA first showed a positive correlation and then a negative correlation. In addition, the thermal stability was slightly reduced, and the hydrophobicity was greatly improved. The CO2 adsorption results revealed that the organic adsorbents exhibited higher adsorption capacity and faster adsorption kinetics than conventional CO2 capture materials, and their simple synthesis enables their industrial application. The study revealed that the preparation of PEI-modified adsorbents with a core–shell structure greatly improved thermal stability and selectivity. When the PEI loading was 50 wt %, the CO2 capacity of the core–shell microspheres reached 3.11 mmol·g–1 at 40 °C, and desorption can be completed at 85 °C. The proposed material has a good industrial application prospect and shows an excellent lifetime performance.
研究领域:
材料科学
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环境工程
·
化学工程
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DOI
高影响因子
Advanced Healthcare Materials
·
2024
·
IF 10
Xuan Qin,Haoliang Shi,Zhen Wen,Binbin Chu,Hongyang Li,Houyu Wang,Yao He,Xuhui Sun
Electrotherapy is of great interest in the field of tissue repair as an effective, well-tolerated, and noninvasive treatment. Triboelectric nanogenerator (TENG) has shown advantages in promoting wound healing due to its peak output characteristic and low Joule heating effect. However, it is limited in infected wound healing due to poor antimicrobial capacity. Here, a wearable triboelectric stimulator (WTS) is developed that consists of a flexible TENG (F-TENG) and a triboelectric-responsive drug delivery hydrogel (TR-DDH) for healing of bacterium-infected wounds. F-TENG can generate pulsed current to wounds by converting mechanical energy from body movements. Polypyrrole is prone to reduction and volume contraction under electrical stimulation, resulting in desorption of curcumin nanoparticles (CUR NPs) from the polypyrrole in TR-DDH. Therefore, the highly efficient and controllable release of CUR NPs can be achieved by triboelectric stimulation. According to the in vitro and in vivo experiments, WTS has the greatest antimicrobial effect and the fastest promotion of infected wound healing compared to treatment with electrical stimulation or curcumin. Finally, the safety assessment demonstrates that the WTS has excellent tissue safety for chronic wound healing. Synergistic therapy with WTS provides an efficient strategy for chronic wound healing and smart-responsive drug delivery systems.
研究领域:
生物医学工程
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纳米技术
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伤口愈合
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药物递送系统
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电疗
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抗菌研究
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DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2019
·
IF 5.256
Jun Yao,Min Chen,Nannan Li,Chaohui Liu,Mei Yang
As an ideal alternative to bisphenol A (BPA), bisphenol S (BPS) has similar biotoxicity, teratogenicity , carcinogenicity and mutagenicity as BPA. Nevertheless, to date, a fast, sensitive and portable method for meeting on-site measurement of BPS had not been established. Hence, it was particularly urged to develop a fast and highly sensitive method for tracing BPS. Currently, a novel molecularly imprinted polymer (MIP) electrochemical sensor had been successfully fabricated for the detection of BPS, wherein the composite of three-doped carbon quantum dots (B, N, F-CQDs) and silver nanoparticles (AgNPs) were utilized as an electron conducting layer, and MIP was applied as recognition element of target molecules. The step-by-step fabrication process and the adsorption capacity of the modified electrode were evaluated by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and chronocoulometry (CC). The results indicated that the synergy between B, N, F-CQDs and AgNPs dramatically improved the sensitivity of the electrode and achieved the amplification of the electrical signal. Meanwhile, the electrochemical activities of BPS were explored by CV and differential pulse voltammetry (DPV). And, the various parameters relating to the electrochemical kinetic properties of BPS were calculated. To the best of our knowledge, this was rarely reported in peer journals. The MIP remarkably improved the selectivity of the sensor owing to the specific recognition of the imprinted cavities. The linear response range of the new sensor was 1 × 10 −8 M to 5 × 10 −5 M with a detection limit of 1.12 × 10 −8 M and the electrode designed in this paper could meet the requirement of trace-level measurement of BPS in biological and environmental samples. Additionally, the sensor was used to determine BPS in plastic products with good anti-interference and acceptable recovery.
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DOI
PubMed
高影响因子
Cell Reports
·
2023
·
IF 8.8
Yingqi Liu,Xuemei Yao,Youbo Zhao,De Fang,Lei Shi,Li Yang,Guanbin Song,Kaiyong Cai,Liqi Li,Qin Deng,Menghuan Li,Zhong Luo
The tumor microenvironment (TME) plays decisive roles in disabling T cell-mediated antitumor immunity, but the immunoregulatory functions of its biophysical properties remain elusive. Extracellular matrix (ECM) stiffening is a hallmark of solid tumors. Here, we report that the stiffened ECM contributes to the immunosuppression in TME via activating the Rho-associated coiled-coil-containing protein kinase (ROCK)-myosin IIA-filamentous actin (F-actin) mechanosignaling pathway in tumor cells to promote the generation of TRIM14-scavenging nonmuscle myosin heavy chain IIA (NMHC-IIA)-F-actin stress fibers, thus accelerating the autophagic degradation of cyclic guanosine monophosphate (GMP)-AMP synthase (cGAS) to deprive tumor cyclic GMP-AMP (cGAMP) and further attenuating tumor immunogenicity. Pharmacological inhibition of myosin IIA effector molecules with blebbistatin (BLEB) or the RhoA upstream regulator of this pathway with simvastatin (SIM) restored tumor-intrinsic cGAS-mediated cGAMP production and enhanced antitumor immunity. Our work identifies that ECM stiffness is an important biophysical cue to regulate tumor immunogenicity via the ROCK-myosin IIA-F-actin axis and that inhibiting this mechanosignaling pathway could boost immunotherapeutic efficacy for effective solid tumor treatment.
研究领域:
癌症生物学
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免疫学
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细胞生物学
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生物物理学
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DOI
PubMed
高影响因子
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