JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2023
·
IF 6.1
Muhammad Noman,Azizullah,Temoor Ahmed,Yizhou Gao,Hui Wang,Xiaohui Xiong,Jiajing Wang,Jiajun Lou,Dayong Li,Fengming Song
The ubiquitin–proteasome system (UPS) regulates protein quality or control and plays essential roles in several biological and biochemical processes in fungi. Here, we present the characterization of two UPS components, FonDoa1 and FonDoa4, in watermelon Fusarium wilt fungus, Fusarium oxysporum f. sp. niveum (Fon), and their biological functions. FonDoa1 localizes in both the nucleus and cytoplasm, while FonDoa4 is predominantly present in the cytoplasm. Both genes show higher expression in germinating macroconidia at 12 h. Deletion of FonDoa1 or FonDoa4 affects vegetative growth, conidiation, conidial germination/morphology, apoptosis, and responses to environmental stressors. FonDoa1, but not FonDoa4, positively regulates autophagy. The targeted disruption mutants exhibit significantly attenuated pathogenicity on watermelon due to defects in the infection process and invasive fungal growth. Further results indicate that the WD40, PFU, and PUL domains are essential for the function of FonDoa1 in Fon pathogenicity and environmental stress responses. These findings demonstrate the previously uncharacterized biological functions of FonDoa1 and FonDoa4 in phytopathogenic fungi, providing potential targets for developing strategies to control watermelon Fusarium wilt.
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DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
·
2024
·
IF 4.3
Shuoxing Yang,Hongping Wu,Zhanggui Hu,Jiyang Wang,Yicheng Wu,Hongwei Yu
Introducing F– anions or substituting F– anions with IO3– groups has been proven to be ideal strategies for designing novel noncentrosymmetric (NCS) and polar materials, yet systematic investigation into the effect of F– anions or the substitution of IO3– for F– anions on structures and properties remains rarely explored. Herein, two new gallium iodates, NaGa(IO3)2F2 (1) and NaGa(IO3)4 (2), were successfully designed and synthesized based on NaGa(IO3)3F by introducing more F– anions and replacing F– anions with IO3 groups, respectively. Structurally, in compound 1, the adjacent [GaF3(IO3)3]3– polyanions are connected in an antiparallel manner, resulting in a complete cancellation of local polarity. While in compound 2, all IO3 groups in 2D [Ga(IO3)4]∞– layers are aligned, leading to large macroscopic polarization. Additionally, chemical substitution also results in a qualitative improvement in the functional properties of compound 2. It possesses strong SHG response (12 × KDP @1064 nm) and broad optical transparency, coupled with large birefringence (0.21 @1064 nm), showcasing its promise as a promising nonlinear optical (NLO) crystal. The effects of chemical substitution between F– anions and IO3– groups on the structures and properties are discussed in detail.
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DOI
PubMed
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2024
·
IF 4.1
Yuxiang Jiao,Yifei Li,Huaijun Tang,Shanglan Xian,Yonghui He,Long Wang,Jinghao Zhang
Herein, a cationic iridium(III) complex [(ppy) 2 Ir(IPP)]PF 6 (ppy: 2-phenylpyridine; IPP: 2-(1 H -imidazo[4,5- f ][1,10]phenanthrolin-2-yl)phenol) was synthesized. Under the excitation of 328 nm (λ ex = 328 nm) UV light, this complex emitted bright yellow orange light (500 ∼ 700 nm, λ em,max = 582 nm), the Stokes shift was up to 254 nm, mainly due to excited-state intramolecular proton transfer (ESIPT) occurring in its ancillary ligand IPP. [(ppy) 2 Ir(IPP)]PF 6 was very sensitive to Ni 2+ , which was caused by the ESIPT being hindered by the coordination of [(ppy) 2 Ir(IPP)]PF 6 with Ni 2+ . Its bright yellow orange light disappeared within 1 min when Ni 2+ (1.0 equiv.) was added in its solution (in DMSO/H 2 O, v/v = 999/1), therefore, it can be used for “turn-off” chemiluminescent detection of Ni 2+ . The recognition of [(ppy) 2 Ir(IPP)]PF 6 to Ni 2+ was not interfered by many common metal ions (such as Na + , K + , Li + , Mg 2+ , Al 3+ , Ca 2+ , Fe 3+ , Ag + , Zn 2+ , Hg 2+ , Co 2+ , Pb 2+ , Mn 2+ , Ba 2+ or Cr 3+ ), however, Cu 2+ was an interfering metal ion, but its interference can be completely masked by thiourea. The detection limit was as low as 3.31 × 10 −7 mol∙L -1 (0.331 μM). The Job’s plot analysis revealed that the stoichiometry of [(ppy) 2 Ir(IPP)]PF 6 with Ni 2+ was 1:1, its detecting mechanism based on ESIPT effect was demonstrated by 1 H NMR spectra and density functional theory (DFT) calculation.
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高影响因子
ENERGY CONVERSION AND MANAGEMENT
·
2023
·
IF 10.4
Pengcheng Zhu,Xuepeng Luo,Xinran Lin,Zhichong Qiu,Rongrui Chen,Xiangcheng Wang,Yaling Wang,Yuan Deng,Yanchao Mao
Flexible thermoelectric devices (f-TEDs) can realize direct energy conversion between heat and electricity, which hold great prospects in wearable power source and personal thermal management. However, conventional f-TEDs made from intrinsically flexible thermoelectric materials have low power density, and elastomer sealed bulk thermoelectric materials-based f-TEDs can hardly achieve active cooling. Additionally, these f-TEDs usually are not self-healable and recyclable, which easily occur fractures in wearable applications. Here, we developed a self-healable and recyclable f-TED by integrating dynamic covalent thermoset polyimine with liquid metal and thermoelectric legs. This f-TED achieves a normalized power density of 1.54 μW·cm −2 ·K −2 , and can deliver a record 13.8 °C on-body cooling effect with a high coefficient of performance (COP) at 3.91 under 7 °C temperature difference, which leads to a low power consumption of ∼ 38 W for the cooling of regular human body. Based on the f-TED, we further developed a personal thermal management system, which can keep body within comfort zone at different surrounding temperatures, also realize healthcare function for fever or sprained ankle. Compared with conventional thermoelectric devices, this f-TED can simultaneously achieve self-healability, recyclability, flexibility, large normalized power density, and high on-body cooling effect with low power consumption. Such f-TED could open up new opportunities to develop devices for wearable energy harvesting and personal thermal management.
研究领域:
材料科学
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热电学
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可穿戴技术
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能量收集
·
个人热管理
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DOI
高影响因子
ACS Applied Energy Materials
·
2025
·
IF 5.5
Dongxue Fan,Kai Cui,Yang Li,Caiqin Miao,Qun Wang,Xiaohong Wu
Flexible perovskite solar cells (F-PSCs) have demonstrated remarkable potential for next-generation wearable platforms. Nonetheless, the reduction of open-circuit voltage (VOC) at the interface within F-PSCs poses a significant barrier to improving the photoelectric conversion efficiency (PCE). Herein, we reported an effective “two birds with one stone” strategy by utilizing carbon dots (CDs) as a multifunctional treatment modulator to modify the SnO2 electron transport layer (ETL) and buried interface. On the one hand, CDs were explored to passivate trap states associated with Sn dangling bonds and oxygen vacancies on SnO2 surfaces through Lewis acid–base coordination, thereby enhancing the electron mobility of SnO2 films and facilitating charge extraction from perovskite layers. On the other hand, the functional groups (including carboxyl, fluorine, and amino) on CDs enable the formation of coordination and hydrogen bonding with PbI2, promoting the formation of high-quality perovskite films with reduced defect densities. The collective enhancements effectively mitigate trap-assisted charge recombination and interfacial energy loss, significantly reducing the device voltage deficit and enabling F-PSCs to attain a PCE of 22.97% with enhanced VOC from 1.06 to 1.18 V. Notably, CDs-incorporated devices demonstrate exceptional operational durability, maintaining 83% of initial PCE after 400 h of continuous illumination (AM 1.5G) in an air atmosphere and retaining 81% PCE following 4000 cyclic bending tests (6 mm radius). This methodology establishes a robust framework for simultaneously enhancing both the efficiency and stability in FAPbI3-based F-PSCs.
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高影响因子
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2023
·
IF 5.7
Weijia Guo,Zhiyu Ma,Yutian Lu,Zhenxing Yue
High- Q and temperature-stable ceramics are indispensable in microwave engineering. However, medium-permittivity ( ε r ∼ 60, named as K60) microwave dielectric ceramics that meet the above demands are yet to be synthesized. High- Q Ba 4 Sm 9.33 Ti 16.5 Al 2 O 54 (BSTA) and Ca 0.6 Sm 0.27 Ti 0.8 Al 0.27 O 3 (CSTA) ceramics have large resonant frequency temperature coefficients ( τ f ) with opposite signs. The composites of the two are expected to have good dielectric properties , but there will be obvious diffusion when they are compounded with each other by sintering after directly mixing the raw powder, which would lead to severe deterioration in dielectric properties. In this work, the undesired diffusion can be effectively avoided by stacking two or three ceramic layers together, which are achieved by two methods named adhesive bonding and spark-plasma-sintering (SPS) cofiring. The finite element method (FEM) analysis with COMSOL Multiphysics proposed in this work can precisely predict the microwave dielectric properties of layered ceramics, helping to determine the ratio of different layers to reach near-zero τ f . The adhesive-bonded layered ceramics exhibit excellent dielectric properties: ε r = 62.2, Q × f = 21,400 GHz, and τ f = –0.7 ppm/°C. The SPS-cofired layered ceramics can be fabricated in one time, partially solving the problem of sintering mismatch between different layers, together with superior properties of ε r = 59.8, Q × f = 19,780 GHz, and τ f = –0.6 ppm/°C. These layered ceramics could fill the gap of high- Q and temperature-stable K60 microwave dielectric ceramics. The layer-stacking process and related FEM simulations can be used to design more high- Q and temperature-stable microwave dielectric ceramics and devices.
研究领域:
材料科学
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陶瓷
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微波工程
·
介电材料
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DOI
高影响因子
Inorganic Chemistry Frontiers
·
2022
·Vol. 9
·期 14
·3590-3597
·
IF 7.779
Qiang Wang,Wen Song,Yang Lan,Liling Cao,Ling Huang,Daojiang Gao,Jian Bi,Guohong Zou
KBe2BO3F2 (KBBF) with a perfect honeycomb hexagonal layered structure is the sole practical deep-ultraviolet (DUV) nonlinear optical material which could generate DUV coherent light through direct frequency doubling. However, the layered growth habit and the toxicity of Be severely hinder its extensive applications. Herein, a non-centrosymmetric fluoride carbonate, KLi2CO3F, was successfully developed via chemical co-substitution with KBBF as the prototype. KLi2CO3F preserves the structural merits of KBBF, containing neatly arranged infinite planar [Li2CO3F2]∞ layers. In particular, compared with the weak interlayer K–F electrostatic attraction in KBBF, KLi2CO3F presents a stronger interlayer binding energy induced by the shorter and stronger Li–F bonds, which effectively overcomes the layered tendency of crystal growth. Simultaneously, KLi2CO3F exhibits a large birefringence of approximately 0.102@546 nm and a short ultraviolet absorption edge down to 190 nm, indicating that it is a promising DUV birefringent material.
研究领域:
材料科学
·
光学
·
晶体学
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DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2022
·
IF 4.326
Mengchen Li,Zhiyu Zhu,Junteng Liu,Junsu Jin,Le Du,Jianguo Mi
A macroporous organic adsorbent was designed and prepared using the template method, with acrylamide (AM) as the skeleton, glycidyl methacrylate (GMA) as the shell, and F-127 and Pluronic block copolymer (P123) as surfactants, and grafted with polyethyleneimine (PEI). Solid adsorbents were used for carbon dioxide capture. The effect of the AM/GMA mass ratio on the spherical morphology, through-hole structure, specific surface area, hardness, hydrophobicity, and thermal stability was comprehensively investigated, and the CO2 adsorption performance of the PEI-modified adsorbent was studied. Surface area and morphology characterization showed that after the introduction of GMA, the wall thickness and roughness increased, and the specific surface area and the mass of GMA first showed a positive correlation and then a negative correlation. In addition, the thermal stability was slightly reduced, and the hydrophobicity was greatly improved. The CO2 adsorption results revealed that the organic adsorbents exhibited higher adsorption capacity and faster adsorption kinetics than conventional CO2 capture materials, and their simple synthesis enables their industrial application. The study revealed that the preparation of PEI-modified adsorbents with a core–shell structure greatly improved thermal stability and selectivity. When the PEI loading was 50 wt %, the CO2 capacity of the core–shell microspheres reached 3.11 mmol·g–1 at 40 °C, and desorption can be completed at 85 °C. The proposed material has a good industrial application prospect and shows an excellent lifetime performance.
研究领域:
材料科学
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环境工程
·
化学工程
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DOI
高影响因子
Advanced Healthcare Materials
·
2024
·
IF 10
Xuan Qin,Haoliang Shi,Zhen Wen,Binbin Chu,Hongyang Li,Houyu Wang,Yao He,Xuhui Sun
Electrotherapy is of great interest in the field of tissue repair as an effective, well-tolerated, and noninvasive treatment. Triboelectric nanogenerator (TENG) has shown advantages in promoting wound healing due to its peak output characteristic and low Joule heating effect. However, it is limited in infected wound healing due to poor antimicrobial capacity. Here, a wearable triboelectric stimulator (WTS) is developed that consists of a flexible TENG (F-TENG) and a triboelectric-responsive drug delivery hydrogel (TR-DDH) for healing of bacterium-infected wounds. F-TENG can generate pulsed current to wounds by converting mechanical energy from body movements. Polypyrrole is prone to reduction and volume contraction under electrical stimulation, resulting in desorption of curcumin nanoparticles (CUR NPs) from the polypyrrole in TR-DDH. Therefore, the highly efficient and controllable release of CUR NPs can be achieved by triboelectric stimulation. According to the in vitro and in vivo experiments, WTS has the greatest antimicrobial effect and the fastest promotion of infected wound healing compared to treatment with electrical stimulation or curcumin. Finally, the safety assessment demonstrates that the WTS has excellent tissue safety for chronic wound healing. Synergistic therapy with WTS provides an efficient strategy for chronic wound healing and smart-responsive drug delivery systems.
研究领域:
生物医学工程
·
纳米技术
·
伤口愈合
·
药物递送系统
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电疗
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抗菌研究
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DOI
高影响因子
CERAMICS INTERNATIONAL
·
2025
·Vol. 51
·期 21
·34195-34202
·
IF 5.6
Zelai Cheng,Xi wang,Mingshan Qu,Xiuling Yang,Xian Jian,Hua Su
With the advent of fifth-generation technology, high-performance microwave dielectric materials with low dielectric constant are urgently needed to enable the miniaturization and integration of communication devices. This study presents the synthesis and characterization of a composite comprising SrCu 0.95 Mn 0.05 Si 4 O 10 (SCSMn) and Ba 3 V 2 O 8 (BV) ceramics, designed for LTCC applications. In a solid-state reaction method, the composition of the synthesized composite was tailored to adjust the τ f value and lower the sintering temperature . The results indicate that the composition of 47.5 wt% SCSMn and 52.5 wt% BV sintered at 925 °C exhibits optimal microwave dielectric properties , including ε r of 8.86, a Q × f of 33860 GHz, and a τ f of 3 ppm/°C. Microstructural analysis revealed that interionic diffusion during sintering induced amorphous phase formation and an increased concentration of defect-associated Cu + and V 5+ species. Concomitant modifications in bond valence summation (BVS) parameters and global instability index (GII) values within the composite ceramics were observed, which collectively account for the discrepancies between theoretical predictions and experimental dielectric properties . The composite material also demonstrated excellent impedance matching and radiation performance when utilized as a substrate for simulating a slot-coupled antenna, validating its promising potential for LTCC applications .
研究领域:
材料科学
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微波工程
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陶瓷与复合材料
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电子材料
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低温共烧陶瓷(LTCC)
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DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2019
·
IF 5.256
Jun Yao,Min Chen,Nannan Li,Chaohui Liu,Mei Yang
As an ideal alternative to bisphenol A (BPA), bisphenol S (BPS) has similar biotoxicity, teratogenicity , carcinogenicity and mutagenicity as BPA. Nevertheless, to date, a fast, sensitive and portable method for meeting on-site measurement of BPS had not been established. Hence, it was particularly urged to develop a fast and highly sensitive method for tracing BPS. Currently, a novel molecularly imprinted polymer (MIP) electrochemical sensor had been successfully fabricated for the detection of BPS, wherein the composite of three-doped carbon quantum dots (B, N, F-CQDs) and silver nanoparticles (AgNPs) were utilized as an electron conducting layer, and MIP was applied as recognition element of target molecules. The step-by-step fabrication process and the adsorption capacity of the modified electrode were evaluated by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and chronocoulometry (CC). The results indicated that the synergy between B, N, F-CQDs and AgNPs dramatically improved the sensitivity of the electrode and achieved the amplification of the electrical signal. Meanwhile, the electrochemical activities of BPS were explored by CV and differential pulse voltammetry (DPV). And, the various parameters relating to the electrochemical kinetic properties of BPS were calculated. To the best of our knowledge, this was rarely reported in peer journals. The MIP remarkably improved the selectivity of the sensor owing to the specific recognition of the imprinted cavities. The linear response range of the new sensor was 1 × 10 −8 M to 5 × 10 −5 M with a detection limit of 1.12 × 10 −8 M and the electrode designed in this paper could meet the requirement of trace-level measurement of BPS in biological and environmental samples. Additionally, the sensor was used to determine BPS in plastic products with good anti-interference and acceptable recovery.
研究领域:
分析化学
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环境科学
·
材料科学
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DOI
PubMed
高影响因子
Cell Reports
·
2023
·
IF 8.8
Yingqi Liu,Xuemei Yao,Youbo Zhao,De Fang,Lei Shi,Li Yang,Guanbin Song,Kaiyong Cai,Liqi Li,Qin Deng,Menghuan Li,Zhong Luo
The tumor microenvironment (TME) plays decisive roles in disabling T cell-mediated antitumor immunity, but the immunoregulatory functions of its biophysical properties remain elusive. Extracellular matrix (ECM) stiffening is a hallmark of solid tumors. Here, we report that the stiffened ECM contributes to the immunosuppression in TME via activating the Rho-associated coiled-coil-containing protein kinase (ROCK)-myosin IIA-filamentous actin (F-actin) mechanosignaling pathway in tumor cells to promote the generation of TRIM14-scavenging nonmuscle myosin heavy chain IIA (NMHC-IIA)-F-actin stress fibers, thus accelerating the autophagic degradation of cyclic guanosine monophosphate (GMP)-AMP synthase (cGAS) to deprive tumor cyclic GMP-AMP (cGAMP) and further attenuating tumor immunogenicity. Pharmacological inhibition of myosin IIA effector molecules with blebbistatin (BLEB) or the RhoA upstream regulator of this pathway with simvastatin (SIM) restored tumor-intrinsic cGAS-mediated cGAMP production and enhanced antitumor immunity. Our work identifies that ECM stiffness is an important biophysical cue to regulate tumor immunogenicity via the ROCK-myosin IIA-F-actin axis and that inhibiting this mechanosignaling pathway could boost immunotherapeutic efficacy for effective solid tumor treatment.
研究领域:
癌症生物学
·
免疫学
·
细胞生物学
·
生物物理学
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DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）