JOURNAL OF APPLIED POLYMER SCIENCE
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2014
·Vol. 131
·期 20
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IF 1.64
Lei Wang,Yandong Li,Jingfen Sun,Yan Lu,Yujiao Sun,Dandan Cheng,Chenxi Li
Because of its interaction with diverse proteins, heparin plays an important role in the regulation of various normal physiological and pathological processes. However, heparin overdose can induce some complications such as hemorrhages and thrombocytopenia. Therefore, it is critical to detect and quantify heparin accurately and quickly. Recently, conjugated polyelectrolytes (CPEs)-based fluorescent probes for heparin sensing have attracted considerable interests. Unfortunately, only few kinds of CPEs such as polyfluorenes derivatives, polythiophene derivatives, are reported and effective in fluorescent assays of heparin by now. This contribution aims to develop a new kind of polyelectrolytes based on poly(pyridinium salt)s derivatives for heparin detection with a light-up signature. An alternative conjugated poly(pyridinium salt)s ( P1 ) containing carbazole segments in the main chain was designed and synthesized, which are weakly emissive in solution but highly luminescent upon binding with heparin. Fluorescence light-up probes for heparin detection based on P1 were developed with high selectivity. P1 shows the similar fluorescence response toward heparin both in a broad pH range of about 3–12 and in the presence of various competing anions. Heparin quantification with a practical calibration range (0–14 µ M ) covering the whole therapeutic dosing levels (0.2–1.2 U mL −1 , 1.7–10 µ M ) is realized based on the polymer probe. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131 , 40933.
研究领域:
高分子化学
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分析化学
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生物传感器
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荧光探针
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生物医学检测
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JOURNAL OF ALLOYS AND COMPOUNDS
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2026
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IF 6.7
Wentong Su,Chunlian Hu,Wei Zhang,Guodong Zhang,Wenke Zhang,Yuantao Chen
Modulating the electronic structure of inorganic semiconductors using biomass is an emerging strategy for developing highly efficient photocatalysts. In this study, Chlorella (Ch) was used as a biological carrier and electron donor, and a bio-inorganic hybrid photocatalyst, Chlorella@ZnIn₂S₄ (ZIS-Ch), featuring bio-induced sulfur vacancy formation, was successfully synthesized via a one-step hydrothermal method. Experimental and characterization results indicate that nitrogen- and oxygen-containing functional groups (–NH 2 , –OH, –COOH) on the Ch surface form interfacial covalent bonds (M–N/O) with Zn 2+ /In 3+ in ZnIn₂S₄, inducing the directed injection of electrons from Ch into the ZnIn 2 S 4 lattice. Concurrently, EPR spectroscopy detected the formation of sulfur vacancies (V S ). Under simulated sunlight and under optimal conditions, the photocatalytic hydrogen production rate of ZIS-Ch40 reached [7.969 mmol⋅g −1 ⋅h −1 ], which is 1.59 times and 5.6 times higher than that of pure ZIS and Ch, respectively, and it maintained good activity even after five cycles. This study provides a new approach for utilizing intact cells to regulate inorganic semiconductor defects and band structures, thereby enabling highly efficient solar hydrogen production.
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Catalysts
·
2026
·Vol. 16
·期 4
·342
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IF 4.5
Yang Deng,Shuhong Wu,Jun Zhu
Driven by the progress of sustainable development, environmental remediation and water treatment have become increasingly important. Photocatalysis, capable of degrading pollutants through light (especially visible light) irradiation, has received widespread research attention. Titanium dioxide(TiO2) is a promising photocatalyst, yet its practical use is limited by low visible-light utilization and rapid photogenerated charge recombination. Herein, an S-scheme TiO2-WO3(Tungsten trioxide) heterojunction was successfully fabricated; the difference in Fermi levels induces a built-in electric field directed from TiO2to WO3, which thus constructs the S-scheme heterojunction. The as-prepared heterojunction exhibits a markedly enhanced transient photocurrent density, with the carrier lifetime prolonged from 2.69 ns to 41.61 ns. Under visible-light irradiation, the heterojunction achieves a methylene blue (MB) removal efficiency of over 95% within 90 min, and its pseudo-first-order kinetic rate constantkreaches 0.032 min−1, which is approximately 16 times that of pure TiO2. Radical trapping experiments confirm that the dominant active species responsible for the catalytic process are photogenerated holes and the hydroxyl radicals derived therefrom.
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Bioresources and Bioprocessing
·
2023
·Vol. 10
·期 1
·1-10
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IF 4.6
Zhang Man,Huang Zheng-Yu,Su Ying,Chen Fei-Fei,Chen Qi,Xu Jian-He,Zheng Gao-Wei
Tetrahydroisoquinoline alkaloids (THIQAs) are ubiquitous compounds with important pharmaceutical and biological activity. Their key N-heterocyclic structural motifs are synthesised via Pictet–Spengler (P–S) reaction by norcoclaurine synthases (NCS) in plants. The synthesis of 1-aryl-tetrahydroisoquinoline alkaloids has attracted increasing attention due to their antitumor and antivirus activities. Herein, the L68T/M97V mutant of NCS from Thalictrum flavum with improved activity was developed by semi-rational design. This mutant not only showed higher catalytic performance (> 96% conversion) toward benzaldehyde and dopamine over the wild-type enzyme, but also catalysed the P–S reaction of the bulky substrate 4-biphenylaldehyde and dopamine with high conversion (> 99%) for the effective synthesis of 1-aryl-THIQA. In terms of stereoselectivity, all products synthesised by the L68T/M97V mutant showed high optical purity (92–99% enantiomeric excess).
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Advanced Healthcare Materials
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2023
·
IF 10
Zhuoran Yang,Chunyu Yang,Dan Yang,Ye Zhang,Qingzhu Yang,Fengyu Qu,Wei Guo
Ferroptosis has recently attracted much attention as an anti-tumor therapy. Evidence suggests that ferroptosis can induce oxidative stress and accumulation of lethal lipid peroxides in cancer cells, leading to cell damage. However, unsuitable pH, H 2 O 2 levels, and high glutathione (GSH) expression in the tumor microenvironment hinder the development of ferroptosis-mediated therapy. In this study, an l -arginine ( l -arg)-modified CoWO 4 /FeWO 4 (CFW) S-scheme heterojunction is strategically designed and constructed for ultrasound (US)-triggered sonodynamic- and gas therapy-induced ferroptosis. CFW not only has excellent Fenton-catalytic activity, outstanding GSH consumption capacity, and excellent ability to overcome tumor hypoxia, but its S-scheme heterostructure can also avoid the rapid combination of electron (e) and hole (h + ) pairs, thereby enhancing the sonodynamic effects. As a precursor of nitric oxide (NO), l -arg is modified on the surface of CFW (CFW@ l -arg) to achieve controlled NO release under US irradiation, thereby enhancing ferroptosis. In addition, poly(allylamine hydrochloride) is further modified on the surface of CFW@ l -arg to stabilize l -arg and achieve controllable NO release. Both in vitro and in vivo results demonstrate that such a multifunctional therapeutic nanoplatform can achieve high therapeutic efficacy through sonodynamic and gas therapy-enhanced ferroptosis. This designed oncotherapy nanoplatform provides new inspiration for ferroptosis-mediated therapy.
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NEW CARBON MATERIALS
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2023
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IF 5.7
Jing-yi Niu,De-qi Jing,Xing-hua Zhang,Wei-guo Su,Shou-chun Zhang
Hollow porous carbon fibers for Li-S battery electrodes were prepared by the KOH activation of carbon prepared from hollow polyacrylonitrile fibers. The fibers had a high specific surface area of 2 491 m 2 ·g −1 , a large pore volume of 1.22 cm 3 ·g −1 and an initial specific capacity of 330 mAh·g −1 at a current density of 1 C. To improve their electrochemical performance, the fibers were modified by treatment with hydrazine hydrate to prepare nitrogen-doped hollow porous carbon fibers with a specific surface area of 1 690 m 2 ·g −1 , a pore volume of 0.84 cm 3 ·g −1 and a high nitrogen content of 8.81 at%. Because of the increased polarity and adsorption capacity produced by the nitrogen doping, the initial specific capacity of the fibers was increased to 420 mAh·g −1 at a current density of 1 C.
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Journal of Environmental Chemical Engineering
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2023
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IF 7.7
Qiang Li,Lijie Wang,Jupu Song,Linshen Zhang,Chunfeng Shao,Hong Li,Hemin Zhang
Construction of heterojunction photocatalysts is a valid tactics to boost the photocatalytic property of catalyst. Herein, a novel S-scheme heterojunction of zero/three dimensional (0D/3D) In 2 S 3 /Bi 2 WO 6 hybrid catalyst was obtained by assembling In 2 S 3 nanoparticles on floriated shaped Bi 2 WO 6 microsphere through a simple precipitation route for the first time. The morphology, structures, composition, chemical and optical properties of the resulting materials were carefully researched through various instruments. The degradation experiments revealed that In 2 S 3 /Bi 2 WO 6 composites exhibited superior photocatalytic behavior for dyes decomposition. The optimized In 2 S 3 /Bi 2 WO 6 composite showed remarkable photocatalytic decomposition Rhodamine B (RhB) and Methylene blue (MB), 16.0 (2.68)-fold and 70.3 (1.66)-fold larger than that of pristine Bi 2 WO 6 (In 2 S 3 ), and it also possessed good stability and reusability. The largely improved photoactivity may derive from the formed S-scheme heterojunction between Bi 2 WO 6 and In 2 S 3 , which accelerated photocarriers disassociation and retained strong redox power. Liquid chromatography-mass spectrometry (LC-MS) was applied to reveal the RhB decomposition pathway. Besides, the S-scheme charge transfer mechanism was well elucidated based on in-situ X-ray photoelectron spectroscopy analysis, density functional theory calculation (DFT), and trapping experiment along with electron paramagnetic resonance (EPR) tests.
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International Journal of Environmental Science and Technology
·
2023
·Vol. 20
·期 11
·11865-11876
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IF 3.1
Xin X.,Liu H.,Sun J.,Gao K.,Jia R.
The composite material based on N- , S- , and Fe-doped TiO 2 (NSFe-TiO 2 ) synthesized by wet impregnation was used as a photocatalyst to rapidly degrade sulfadiazine. The photocatalytic degradation behavior and mechanism of sulfadiazine on NSFe-TiO 2 were investigated for revealing the role of degradation under ultraviolet light. The results showed that compared with TiO 2 , NSFe-TiO 2 markedly improved the efficiency in photocatalytic degradation of sulfadiazine: more than 90% of sulfadiazine could be removed within 120 min by NSFe-TiO 2 dosage of 20 mg L −1 . The process conformed to first-order reaction kinetics model. The parameters such as loaded amount of NSFe-TiO 2 , solution pH value, humic acid concentration and recycle numbers on removal efficiency were also studied. Compared to neutral and alkaline conditions, acidic condition was not conducive to the photocatalysis. HA, Ca 2+ , Cu 2+ and Zn 2+ in the actual water body had mild inhibition on sulfadiazine degradation in UV/NSFe-TiO 2 system. Fragments screened by high-resolution mass spectrometry were conducted to explore the oxidation mechanism and pathways of sulfadiazine degradation. On the whole, UV/NSFe-TiO 2 photocatalysis has a good effect on sulfadiazine removal.
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ELECTROCHIMICA ACTA
·
2023
·
IF 6.6
Xianwei Geng,Chenguang Liu,Chun Zhao,Zhongjie Jiang,Eng Gee Lim,Yongjie Wang,Ivona Mitrovic,Li Yang,Pengfei Song
As a novel two-dimensional (2D) layered material, Ti 3 C 2 T x MXene has excellent electronic conductivity and strong polysulfides adsorption. Its potential for Li-S batteries has been well recoginised since it can compensate conductivity of sulfur and improve cycling stability simultaneously. However, like other 2D materials , the stacking feature of the MXene nanosheet greatly limits its advantages and applications. Herein, a sulfydryl-modified MXene - sulfur cathode is synthesized via simple hydrothermal and copolymerization reactions. Compared to the conventional physical absorption between MXene and polysulfide, it was found that a chemical modification of MXene offers a much robust structure with little stacking on MXene. During the discharge process high-order Li 2 S 4 intermediates were first formed but consumed immediately. The remaining polysulfides are only short chains of Li 2 S, Li 2 S 2 and Li 2 S 3 . This type of cathode can greatly suppress the “shuttle effect” by reducing the generation of soluble high-order polysulfides in the electrolyte, which is attributed to rapid capacity fading. As a result, the cathode achieves an excellent initial specific capacity of 1367 mAh·g −1 at 0.1 C. It also has a high first capacity of 880 mAh·g −1 and remains 715 mAh·g −1 after 500 cycles at 1 C, with a retention rate of 81.3%. Our work provides a new strategy for applying MXene in the Li-S battery field.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2022
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IF 9.965
Shiwei Song,Yanhui Wang,Xueqing Tian,Fanjia Sun,Xiaoxu Liu,Yungang Yuan,Wei Li,Jianbing Zang
For sustained hydrogen generation from seawater electrolysis, an efficient and specialized catalyst must be designed to cope with the slow anode reaction and chloride ions (Cl - ) corrosion. In this work, an S-modified NiFe-phosphate with hierarchical and hollow microspheres was grown on the NiFe foam skeleton (S-NiFe-Pi/NFF), acting as a bifunctional catalyst to enable industrial-scale seawater electrolysis. The introduction of S distorted the lattice of NiFe-phosphate and regulated the local electronic environment around Ni/Fe active metal, both of which enhanced the electrocatalytic activity. Additionally, the existence of phosphate groups repelled Cl - on the surface and enhanced corrosion resistance, enabling stable long-term operation in seawater. The double-electrode electrolyzer composed of the hollow-structured S-NiFe-Pi/NFF as both cathode and anode exhibited a potential of 1.68 V at 100 mA cm −2 for seawater electrolysis. Particularly, to achieve industrial requirements of 500 mA cm −2 , it only required a low cell voltage of 1.8 V and demonstrated a consistent response over 100 h, which outperformed the pair of Pt/C || IrO 2 . This study provides a feasible idea for the preparation of electrocatalysts that are with both highly activity and corrosion resistance, which is crucial for the implementation of industrial-scale seawater electrolysis.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2022
·
IF 24.319
Miaoli Gu,Yi Yang,Liuyang Zhang,Bicheng Zhu,Guijie Liang,Jiaguo Yu
Solar H 2 O 2 generated from O 2 and H 2 O is an economical and green protocol. However, most photocatalysts only perform well in the presence of sacrificial donors or the photocatalysts are composed by organic materials, thus hindering their applicability. Herein, an inorganic matrix, i.e. ZnIn 2 S 4 @BiVO 4 (ZIS@BVO), is constructed as a model catalyst for photocatalytic H 2 O 2 production in non-sacrificial systems. Excellent performance (1.8 mmol g −1 h −1 ) under visible-light is realized, and an apparent quantum yield of 5.18% is realized at 420 nm. Thorough investigation helps us to rationalize its exceptional performance and structural characteristics. Of note, the electron spin resonance spectroscopy results, in combination with scavenger capture experiments, reveal the discovery of an overlooked pathway. Specifically, except for the well-known two-electron oxygen reduction reaction (ORR), the involvement of 1 O 2 intermediate is verified during the H 2 O 2 generation. Beyond presenting high performance of the inorganic composites, this finding also discloses a different reaction path for H 2 O 2 production.
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Biomaterials Science
·
2022
·Vol. 11
·期 3
·894-907
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IF 7.59
Yiran Wang,Mingxi Yang,Jiayi Zhang,Jingyan Ren,Ning Liu,Bin Liu,Laijin Lu,Bai Yang
Myocardial fibrosis (MF) is a critical pathological lesion in the progression of various acute and chronic cardiovascular diseases. However, there is still a lack of clinically effective drugs and treatments for MF therapies. Herein, for the first time, we developed fluorescent sulfur-doped carbonized polymer dots (S-CPDs) as new nano-antioxidants to reduce the cardiomyocyte damage caused by reactive oxygen species (ROS) in the early stage of fibrotic lesions. In vitro results suggested that the pre-protection of S-CPDs significantly increased the survival rate of H9c2 cells under severe oxidative stress, inhibited the isoproterenol (ISO)-induced hypertrophy of myocardial cells through improving the content of mitochondria related proteins and adenosine triphosphate (ATP) in cells. Moreover, S-CPD administration could effectively decrease cardiac hypertrophy and promote heart function in MF rat models. The rapid internalization, high biocompatibility and fluorescence imaging potential of S-CPDs revealed their promising application prospects in the diagnoses and treatments of cardiovascular diseases.
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