MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 9
·1-9
·
IF 6.232
Song Yiju,Qiao Jingwen,Li Wenjun,Ma Chaoyun,Chen Siyu,Li Hongling,Hong Chenglin
A molybdenum disulfide based graphite phase carbon nitride (MoS 2 /g-C 3 N 4 ) which is supported by a platinum-copper nanoparticle (PtCu) Z-type catalyst was created in this study. The catalyst exploits optoelectronic synergistic effect with large surface area, good catalysis, and biocompatibility to amplify the signal. The electrode impedance of the synthesized MoS 2 /g-C 3 N 4 -PtCu was reduced five times in visible light compared with dark conditions, thereby improving the detection of carcinoembryonic antigen (CEA). At a voltage of − 0.4 V, the immunoprobe constructed with this material is used for CEA detection. A linear relationship between 100 fg mL −1 and 80 ng mL −1 concentrations was achieved with a minimum detection limit of 33 fg mL −1 (S/ N = 3). The recovery rate was 103–104%, and the relative standard deviation was 2.9–3.8%. This implies that the sandwich immunosensors have good reproducibility, selectivity, and stability and can be used in various applications.
Graphical Abstract
研究领域:
生物医学工程
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
Environmental Earth Sciences
·
2016
·Vol. 75
·期 2
·1-8
·
IF 0
Li Hongbing,Zhang Xinying,Liu Xiaoyan,Hu Xing,Wang Qian,Hou Yunyun,Chen Xueping,Chen Xiao
Rhizodeposition is considered as a main strategy for plants to regulate its rhizospheric microorganisms. However, effect of rhizodeposition on degradation of polycyclic aromatic hydrocarbons (PAHs), and the alterations of soil structure and microbial community are still unclear, especially in metal–PAHs co-contaminated soils. The study focused on illustrating the microcosm changed by rhizodeposition to find out the dominating factors for the dissipation of pyrene. The analysis results with Fourier transform infrared spectroscopy (FT-IR) showed that the relative abundance of some functional groups in humic acids was amplified by rhizodeposition effect. A result was observed that soluble fraction of lead was rapidly transformed into other fractions by the rhizodeposits. It was found that the rhizodeposition effect exhibited considerable improvement in the degradation of pyrene especially in the lead–pyrene co-contaminated soils. Phospholipid fatty acid analysis (PLFA) showed substantial differences in microbial communities between incubation time and rhizodeposition effect. The studied results further revealed the removal mechanism of pyrene in pyrene–lead co-contaminated soils.
研究领域:
环境科学
·
微生物学
✓ 已验证
DOI
BIOPROCESS AND BIOSYSTEMS ENGINEERING
·
2018
·Vol. 42
·期 2
·279-290
·
IF 2.139
Bin Zou,Yanhong Chu,Jiaojiao Xia
A novel and highly stable biomimetic oxidase sensor system was designed for catehol detection. FePP used as biomimetic horseradish peroxidase (HRP) was immobilized onto modified multi-walled carbon nanotubes (MWCNTs). Functional groups such as –OH, –NH 2 and –COOH were introduced onto the surface of MWCNTs to provide biomimetic microenvironment for iron porphyrins (FePP). Stable biomimetic enzyme electrode has been developed to detect catechol as a simple, economical and efficient method. At optimal condition, the detection limit of OH-MWCNTs/FePP/Nafion was 3.754 × 10 − 6 M. After stored at − 4 °C for 35 days, the oxidation current value still maintained 98.3% of initial activity. In repetitive nature test, relative standard deviation (RSD) of oxidation current remained within 1.0% after ten consecutive measurements in the same concentration of catechol solution, while most of reported oxidase sensor was within 2.0% under the same condition.
研究领域:
分析化学
·
生物传感技术
·
环境监测
✓ 已验证
DOI
PubMed
高影响因子
SN Applied Sciences
·
2020
·Vol. 2
·期 4
·1-12
·
IF 0
Xiao Haimei,Cai Lei,Chen Shan,Zhang Zhaohui
In this work, a facile protein imprinted polymer based on magnetic rich-amine mesoporous silica/graphene oxide was synthesized using dopamine as the functional monomer and bovine hemoglobin as the template molecule. Fe 3 O 4 nanoparticles were introduced onto graphene oxide by an inverse microemulsion method for facilitating surface polymerization dopamine imprinted layer. The protein adsorption test showed that the imprinted layer based on magnetic rich-amine mesoporous silica/graphene oxide can significantly shorten the adsorption equilibrium time of the imprinted polymer toward bovine hemoglobin. Under optimized conditions, the imprinting factor and maximum adsorption capacity of the magnetic imprinted polymer toward bovine hemoglobin was 2.09 and 164.5 mg g −1 , respectively. Several experimental parameters including temperature and pH of solution, type and volume of elution solvent, washing solvent, extraction time were investigated in detail. Combined with magnetic solid phase extraction and high performance liquid chromatography, the magnetic imprinted polymers was successfully applied to rapid separate and enrich bovine hemoglobin from bovine serum with the recoveries of 84.6–102.5%.
研究领域:
生物化学
·
材料科学
·
分析化学
✓ 已验证
DOI
Frontiers of Environmental Science & Engineering
·
2020
·Vol. 14
·期 3
·1-11
·
IF 4.053
Zhu Feng,Yao Zhijian,Ji Wenliang,Liu Deye,Zhang Hao,Li Aimin,Huo Zongli,Zhou Qing
In this study, a hydrophilic resin named GCHM was fabricated based on poly( N -vinyl pyrrolidone- co -divinylbenzene), characterized, and applied as a solid-phase extraction (SPE) material. Up to 44 pharmaceuticals and personal care products (PPCPs) belonging to 10 classes were recovered in environmental water samples. Different variables affecting extraction, such as adsorbent amount, sample pH, and loading speed, were optimized. Under optimal conditions, the average absolute recovery of 44 PPCPs was 75.6% using GCHM, indicating a better performance than the commercial Oasis ® HLB. SPE with home-made hydrophilic polymeric sorbent followed by ultra-performance liquid chromatography and tandem mass spectrometry was validated, and the method achieved good linearity ( r 2 >0.991, for all analytes). In addition, the method detection limits of target compounds ranged from 0.03 to 0.6 ng/L. The developed method was applied to determine PPCPs in 10 environmental water samples taken from the Yangtze River, Huaihe River, and Taihu Lake, 1 groundwater sample from Changzhou in Jiangsu Province, 1 wastewater sample from Xiamen and 2 seawater samples from the Jiulong River in Fujian Province, China. In these samples, 22 compounds were determined at levels ranging from 0.5 to 1590 ng/L.
研究领域:
环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
Frontiers of Chemical Science and Engineering
·
2023
·Vol. 17
·期 11
·1765-1775
·
IF 4.5
Xu Jialiang,Jian Jian,Dan Yixiao,Song Jie,Meng Lingxi,Deng Pei,Sun Weijie,Zhang Yusheng,Xiong Jinhua,Yuan Zhengqiu,Zhou Hu
A stable and recyclable of BiOBr/silk fibroin-cellulose acetate composite film was prepared by blending-wet phase transformation and in situ precipitate technology. The cellulose acetate film modified by silk fibroin formed a finger-shaped porous structure, which provided a large space for the uniform growth of BiOBr nanosheets and facilitated the shuttle flow of dyes in film. The morphology, phase structure, and optical properties of the composite films were characterized using various techniques, and their photocatalytic performance for dye wastewater was evaluated under visible light irradiation. Results showed that the BiOBr/SF-CA composite film exhibited efficient photocatalytic activity with 99.9% of rhodamine B degradation rate. Moreover, the composite film maintained high catalytic stability because Bi as the active species deposited on the film showed almost no loss. Finally, the possible photocatalytic mechanisms in the BiOBr/SF-CA composite film were speculated through radical-trapping experiments and electron spin resonance testing.
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2022
·Vol. 38
·期 5
·1258-1262
·
IF 2.726
Zhang Xingcong,Zhong Yunzhu,Chen Hongyu,Cheng Yujie,Sun Qingdi,Zhang Hao,He Qian,Zhang Ying,Guo Guanghui,He Xiaohui,Ji Hongbing
Through screening Ce precursors and pyrolysis temperatures [Ce(acac) 3 as Ce precursors and pyrolysis at 900 °C], zeolitic imidazolate framework-8(ZIF-8) derived nitrogen-doped carbon supported cerium single atom catalyst(Ce 1 /NC) is successfully prepared by ball milling method. The Ce 1 /NC catalyst exhibits exceptional catalytic performance in the selective oxidation of saturated C-H bonds in aromatic compounds, e.g. , 91% conversion and 99% selelctivity can be achieved in the oxidation of ethylbenzene to acetophenone under mild reaction conditions.
研究领域:
催化化学
·
材料科学
✓ 已验证
DOI
高影响因子
Biomass Conversion and Biorefinery
·
2022
·
IF 4.05
Zhao Rui,Xiao Na,Liu Yufei,Zhan Wei,Wu Zhengshun
In order to solve the pollution problem of agricultural waste and realize the harmlessness, reduction and resource of abandoned rice husk, silica was successfully extracted from rice husk by sol–gel method and used for methane decomposition to produce hydrogen. The effects of reaction temperature and mass fraction of sodium carbonate on the yield of silica were studied. When the reaction temperature was 120℃ and Na 2 CO 3 was 9 wt.%, the yield of silica was 52.3%. The effects of acid on the pyrolysis behavior of rice husk and the purity and the specific surface area of derived silica were investigated. The results showed that the thermal stability of rice husk and the purity of SiO 2 were improved after acid pretreatment. Compared with the silica sample prepared without acid pretreatment (4.7m 2 /g), the specific surface area of the silicon dioxide pretreated by HAc (SiO 2 -HAc) increased to 27m 2 /g. Rice husk-derived silica was used as a catalyst to produce hydrogen from methane decomposition, SiO 2 -HAc showed good catalytic activity, and the conversion of methane increased from 17.01% to 38.83%. This change was attributed to the formation of –Si‒C‒ species, which promoted the decomposition of methane. On this basis, Ni/SiO 2 -HCl and Ni/SiO 2 -HAc catalysts were prepared by loading metal Ni on the surface of rice husk-derived silica, and the conversion of methane increased to 74.33% and 60.73%, respectively.
研究领域:
环境科学
·
材料科学
·
催化化学
✓ 已验证
DOI
高影响因子
Microbiome
·
2017
·Vol. 5
·期 1
·1-18
·
IF 8.496
Hill Cian J.,Lynch Denise B.,Murphy Kiera,Ulaszewska Marynka,Jeffery Ian B.,O’Shea Carol Anne,Watkins Claire,Dempsey Eugene,Mattivi Fulvio,Tuohy Kieran,Ross R. Paul,Ryan C. Anthony,O’ Toole Paul W.,Stanton Catherine
Background The gut is the most extensively studied niche of the human microbiome. The aim of this study was to characterise the initial gut microbiota development of a cohort of breastfed infants ( n = 192) from 1 to 24 weeks of age. Methods V4-V5 region 16S rRNA amplicon Illumina sequencing and, in parallel, bacteriological culture. The metabolomic profile of infant urine at 4 weeks of age was also examined by LC-MS. Results Full-term (FT), spontaneous vaginally delivered (SVD) infants’ microbiota remained stable at both phylum and genus levels during the 24-week period examined. FT Caesarean section (CS) infants displayed an increased faecal abundance of Firmicutes ( p < 0.01) and lower abundance of Actinobacteria ( p < 0.001) after the first week of life compared to FT-SVD infants. FT-CS infants gradually progressed to harbouring a microbiota closely resembling FT-SVD (which remained stable) by week 8 of life, which was maintained at week 24. The gut microbiota of preterm (PT) infants displayed a significantly greater abundance of Proteobacteria compared to FT infants ( p < 0.001) at week 1. Metabolomic analysis of urine at week 4 indicated PT-CS infants have a functionally different metabolite profile than FT (both CS and SVD) infants. Co-inertia analysis showed co-variation between the urine metabolome and the faecal microbiota of the infants. Tryptophan and tyrosine metabolic pathways, as well as fatty acid and bile acid metabolism, were found to be affected by delivery mode and gestational age. Conclusions These findings confirm that mode of delivery and gestational age both have significant effects on early neonatal microbiota composition. There is also a significant difference between the metabolite profile of FT and PT infants. Prolonged breastfeeding was shown to have a significant effect on the microbiota composition of FT-CS infants at 24 weeks of age, but interestingly not on that of FT-SVD infants. Twins had more similar microbiota to one another than between two random infants, reflecting the influence of similarities in both host genetics and the environment on the microbiota.
研究领域:
微生物学
·
儿科
·
分子生物学
✓ 已验证
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 9
·1-10
·
IF 6.232
Li Zi-Ling,Zhang Zi-Yang,Zhao Teng-Wen,Meng Chun-Yan,Zhang Qian-Ying,Wang Man-Man
A novel zeolite imidazole framework@hydroxyapatite composite (ZIF-8@HAP) was constructed via in-situ growth and developed for efficient dispersive solid-phase extraction (DSPE) of three benzodiazepines from urine samples. The prepared composite was characterized by scanning electron microscopy, energy-dispersive spectrometer, Fourier-transform infrared spectrometry, X-ray diffractometry, zeta potential analyzer, and nitrogen adsorption-desorption experiment. Characterization results showed typical dodecahedron ZIF-8 crystals that were uniformly located on the surface of rod-like HAP. The combination of ZIF-8 and HAP made the surface area significantly enhanced from 4.68 to 205.44 m 2 g −1 . Compared with a commercial C 18 adsorbent, ZIF-8@HAP exhibited superior removal performance for interfering components from urine and offered better extraction properties for the analytes. The prepared ZIF-8@HAP was applied as an adsorbent in DSPE, and the main experimental parameters, including pH and ionic strength of solution, adsorbent amount, adsorption time, elution solvent, and volume, were investigated. Under optimal conditions, the adsorption for 250 ng mL −1 of each analyte in 4 mL of urine was accomplished within 2 min using 60 mg of adsorbent. The method of ZIF-8@HAP–based DSPE followed by high-performance liquid chromatography gave enhancement factors of 13.3–15.3, linear ranges of 2.5–500 ng mL −1 , and limits of detection ( S/N = 3) of 0.7–1.4 ng mL −1 . The relative recoveries at three spiked levels ranged from 88.7 - 102% with intra-day and inter-day precisions from 3.0 - 10.3% and 2.3 - 12.3%, respectively. These results indicated that the proposed strategy had promising applicability for convenient, rapid, and efficient determination of benzodiazepines in urine samples. Graphical abstract In-situ fabrication of ZIF-8@HAP composite for dispersive solid-phase extraction of benzodiazepines in urine samples.
研究领域:
分析化学
·
医学检测
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
Journal of Advanced Ceramics
·
2022
·Vol. 11
·期 10
·1530-1541
·
IF 11.534
Zhang Chang,Hu Xiangchen,Nie Zhiwei,Wu Cong,Zheng Nan,Chen Shaojie,Yang Yihang,Wei Ran,Yu Jiameng,Yang Nan,Yu Yi,Liu Wei
Garnet-type oxide is one of the most promising solid-state electrolytes (SSEs) for solid-state lithium-metal batteries (SSLMBs). However, the Li dendrite formation in garnet oxides obstructs the further development of the SSLMBs seriously. Here, we report a high-performance garnet oxide by using AlN as a sintering additive and Li as an anode interface layer. AlN with high thermal conductivity can promote the sintering activity of the garnet oxides, resulting in larger particle size and higher relative density. Moreover, Li 3 N with high ionic conductivity formed at grain boundaries and interface can also improve Li-ion transport kinetics. As a result, the garnet oxide electrolytes with AlN show enhanced thermal conductivity, improved ionic conductivity, reduced electronic conductivity, and increased critical current density (CCD), compared with the counterpart using Al 2 O 3 sintering aid. In addition, Li symmetric cells and Li∣LiFePO 4 (Li∣LFP) half cells using the garnet electrolyte with the AlN additive exhibit good electrochemical performances. This work provides a simple and effective strategy for high-performance SSEs.
研究领域:
材料科学
·
电化学
·
能量存储
✓ 已验证
DOI
高影响因子
MEDICINAL CHEMISTRY RESEARCH
·
2022
·Vol. 31
·期 6
·936-948
·
IF 2.351
Hu Shijia,Li Yunqi,Kan Weiqiong,Ding Tingting,Gu Haijun,Zhang Ting,Yi Zhengfang,Chen Yihua
A series of diphenyl- N -heteroaromatic compounds were designed, synthesized, and evaluated for anticancer efficacies (antimigration and antiproliferation) against human cancer cell lines. The favorable 2 H -1,2,3-triazole compound 4a was optimized, leading to the discovery of compounds 4b and 4c with more potent antimigratory and antiproliferative activities. The transwell assay showed that compounds 4b and 4c dose-independently inhibited the migration of the two cancer cell lines (human breast cancer cell line MDA-MB-231 and pancreatic cancer cell line PANC1) with the low IC 50 values of 0.24 and 0.47 µM, respectively. The sulforhodamine-B (SRB) assay showed that compounds 4b and 4c inhibited the proliferation of PANC1 cells with the IC 50 values 0.86 µM and 1.41 µM, respectively. These results indicate that compounds 4b and 4c with 1,2,3-triazole scaffold may be further developed as potent anticancer agents in the future.
A series of novel diphenyl- N -heteroaromatics based on our previous published research work were synthesized and evaluated for their antimigration efficacies against MDA-MB-231 and PANC1 human cancer cell lines. Compound 4c dose-independently inhibited the migration of the two cancer cell lines (MDA-MB-231 and PANC1) with low IC 50 values 0.32 µM and 0.24 µM respectively.
研究领域:
药理学
·
肿瘤学
·
有机化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）