SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Yilin Wang,Pengjuan Ni,Shu Jiang,Wangdong Lu,Zhen Li,Hanmeng Liu,Jing Lin,Yujing Sun,Zhuang Li
In this paper, a novel, selective and eco-friendly biosensor has been fabricated and applied for sensitive detection of antibiotic oxytetracycline (OTC). This fluorescent biosensor was based on carbon quantum dots (CDs), H 2 O 2 and Fe 3 O 4 magnetic nanoparticles (Fe 3 O 4 MNPs). Herein, we firstly demonstrated that the fluorescence of CDs decreased apparently in the presence of OTC, H 2 O 2 and Fe 3 O 4 MNPs. The fluorescence quenching of CDs not only is caused by the hydroxyl radical produced from the Fenton reaction and complexation of Fe 3 O 4 MNPs with OTC, but also might be related to the inner filter effect (IFE) between CDs and OTC, which improved the selectivity and sensitivity of the fabricated biosensor. Under the optimal experiment conditions, the relative fluorescence intensity of the CDs decreased linearly with the increasing concentration of OTC from 25 nM to 1.75 μM. The detection limit of the fabricated biosensor on OTC was 9.5 nM at a signal-to-noise ratio of 3. Compared with other current protocols, the method described here displayed a few advantages including simplicity, low cost and rapid detection. The precision and reproducibility of the proposed sensor were also acceptable Significantly, the practicality of this sensitive sensor for OTC detection in drugs was further validated, revealing the advantages of high simplicity, sensitivity and selectivity. Hence, the developed biosensor might provide a useful and practical tool for OTC determination and related food safety analysis and clinical diagnosis.
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2021
·Vol. 25
·期 3
·1073-1081
·
IF 2.647
Jin Xin,Lv Mengmeng,Pan Qing,Fang Shu,Zhu Ningning
We describe a label-free electrochemical aptasensor for adenosine triphosphate (ATP) assay based on bifunctional Fe 3 O 4 @Au nanocomposites. Due to the introduction of Au nanoparticles, the resulting bifunctional Fe 3 O 4 @Au nanocomposites can be easily modified with ATP-specific aptamer molecules through Au–S interaction to build the nanoprobe and used to immobilize on a glassy carbon electrode simply with the assistance of a magnet. Once exposed to the target ATP, the current signal obtained at nanoprobe-containing magnetic glassy carbon electrode decreases immediately. The decrease in sensor current is a result of the less methylene blue adsorbed on the aptamer caused by the fact that the ATP-specific aptamer prefers to bind with ATP rather than with methylene blue. The decrease in sensor current can be used for electrochemical determination of ATP, for example, to determine ATP in human serum samples.
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2020
·
IF 4.389
Zideng Dai,Wen Wen,Zhaoming Guo,Xue-Zhi Song,Kun Zheng,Xinyu Xu,Xiuyu Qi,Zhenquan Tan
In this study, we integrated chemotherapy and photothermal therapy in a magnetically targeted doxorubicin-loaded Fe 3 O 4 @SiO 2 nanodrug system. Size-controllable magnetic Fe 3 O 4 @SiO 2 core-shell nanoparticles were synthesized via a solvothermal method and a modified Stǒber method. A molecular anticancer drug, namely, doxorubicin, was loaded onto Fe 3 O 4 @SiO 2 nanocomposites to form a magnetically targeted drug delivery system. This drug delivery system exhibits pH-sensitive effects on drug loading and release. The drug loading rate in a neutral environment is higher than that in an acidic environment; the opposite property is observed for the release rate. In addition, the magnetic Fe 3 O 4 @SiO 2 nanocomposites exhibit a satisfactory photothermal effect under NIR (808 nm) irradiation. The temperature can increase to 55 °C after only 10 min of irradiation, which effectively induces apoptosis of cancer cells in vitro . The cytotoxicity and cellular uptake of Fe 3 O 4 @SiO 2 @DOX nanodrugs were evaluated in A549 lung cancer cells. After treatment with Fe 3 O 4 @SiO 2 @DOX that contains only 10 μg/mL of DOX, 82.8% of A549 lung cancer cells can be killed. Furthermore, 81.3% of A549 lung cancer cells are killed after incubation with Fe 3 O 4 @SiO 2 @DOX that contains only 0.5 μg/mL of DOX and 15 min of NIR irradiation, thereby suggesting an excellent synergistic chemo-photothermal effect in tumour therapy. Our results suggest a new approach for the synthesis of a multifunctional, highly targeted, size-controlled nanodrug for tumour synergistic therapy.
✓ 已验证
DOI
PubMed
高影响因子
POLYMER ENGINEERING AND SCIENCE
·
2025
·
IF 3.2
Huiqiao Xu,Kaijun Wang,Yunping Li,Jing Wang,Jiale Wu,Jiangfeng Mou,Rui Chen,Yafei Wang,Xinyue Wang,Jin Hu
To overcome the challenges of insufficient flexibility and limited absorption performance in conventional electromagnetic wave (EMW) absorbers, this study synthesized a flexible ternary composite composed of EGaIn/TPU/Fe 3 O 4 via ultrasonic dispersion and magnetic stirring encapsulation. Due to the synergistic interaction between the liquid metal conductive network, Fe 3 O 4 magnetic loss units, and the elastic TPU matrix, the composite simultaneously exhibits excellent mechanical flexibility and EMW absorption. With 5 vol% Fe 3 O 4 loading, the composite achieves a minimum reflection loss (RL min ) of −41.4 dB and an effective absorption bandwidth (EAB) of 2.25 GHz at 1.5 mm, while maintaining outstanding mechanical properties (including tensile strength of 10.9 MPa, elongation at break of 658.7%, and elastic modulus of 3.56 MPa). This “conductive-magnetic-flexible” synergistic design provides valuable guidance for the developing of next-generation flexible stealth coatings and wearable electromagnetic shielding materials. Highlights Conductive-magnetic-flexible design is enabled by EGaIn/Fe 3 O 4 /TPU composites. Composites exhibit strong mechanical stability and wearable properties. The synergistic EGaIn/Fe 3 O 4 /TPU structure achieves excellent MA performance.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2018
·Vol. 6
·期 22
·3762-3769
·
IF 4.776
Jiao Ma,Lingjie Song,Hengchong Shi,Huawei Yang,Wei Ye,Xin Guo,Shifang Luan,Jinghua Yin
Improving the detection sensitivity of enzyme linked immunosorbent assay (ELISA) is of the utmost importance for meeting the demand of early disease diagnosis. In this work, a sensitive solid substrate for ELISA, i.e., hierarchical iron oxide magnetic microspheres, Fe3O4@mSiO2@poly[poly(ethylene glycol) methacrylate-co-glycidyl methacrylate], was developed via a novel surface-initiated photoiniferter-mediated polymerization (SI-PIMP) strategy. The magnetic microspheres consist of a magnetic Fe3O4 core that gives a high magnetic response, a 3D backbone, a mesoporous SiO2 middle layer, that facilitates microsphere stability and provides anchoring sites, and polymer brushes, that serve as an antifouling and oriented antibody immobilization layer. As a result, the as-prepared microspheres possess a high antibody loading capacity, an enhanced detection signal and a dramatically improved sensitivity, resulting in a 25-fold improvement over conventional ELISA solid substrates.
✓ 已验证
DOI
PubMed
高影响因子
Journal of Materials Chemistry B
·
2022
·Vol. 10
·期 30
·5784-5795
·
IF 7.571
Jingbo Lin,Jiaxin Zhang,Kuang Wang,Shengdi Guo,Wuli Yang
Ferroptosis, as a form of cell death different from apoptosis, is very promising for the treatment of cancer in nonapoptotic systems. Since iron is a key component in the induction of ferroptosis in cells, the use of iron-based nanomaterials in treating cancer through ferroptosis is of great significance. Therefore, in this study, magnetic nanoparticles (MNP) were coated with the zwitterionic polymer poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC), and then loaded with sorafenib (SRF) to obtain drug-loaded composite nanoparticles MNP@PMPC-SRF. Fe3O4 provided a large number of ferric/ferrous ions as an iron source, releasing Fe2+ for the regulation of the ferroptosis process and enhancing the effect of the induced cellular ferroptosis on the treatment of colon cancer with SRF. The zwitterionic polymer PMPC effectively extended the blood circulation time, resulting in an enhanced tumor accumulation of the nanodrug. MNP@PMPC-SRF exhibited good biocompatibility for in vivo application and showed an excellent tumor inhibitory effect on HCT116 tumor-bearing nude mice.
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2017
·
IF 6.216
Zhiman Yang,Xiaoshuang Shi,Meng Dai,Lin Wang,Xiaohui Xu,Rongbo Guo
Potential of effluents from biological hydrogen production process to improve ciprofloxacin (CIP) removal was investigated using ciprofloxacin-degrading enrichments in the presence of Fe 3 O 4 nanoparticles . Effluent addition clearly promoted CIP removal, which was 61%, 38% and 16% higher than those in the enrichments amended with fecal sewage , biogas digestate and water, respectively. Experiments of sterilization and organic components of effluents indicated that the organic substances served as co-metabolic substrate to facilitate CIP removal, where ethanol was the preferred co-metabolic substrate. Although the effluent addition changed the bacterial community composition which corresponded to the changes in the relative abundances of dominant genera in the enrichments, CIP removal performance remained unchanged. The increased Fe (II) concentrations indicated that there might be a positive relationship of CIP removal with the microbial reduction of Fe (III) to Fe (II) in Fe 3 O 4 in the effluents-amended enrichments. It was proposed that the organic substances in the effluents might serve as the co-metabolic substrate to promote CIP removal by CIP-degrading and Fe (III)-reducing bacteria.
✓ 已验证
DOI
高影响因子
ELECTROANALYSIS
·
2020
·Vol. 33
·期 3
·723-732
·
IF 2.544
Lincai Peng,Yingjie Luo,Hongping Xiong,Shun Yao,Minghui Zhu,Hang Song
A novel enzymatic biosensing platform toward glucose is achieved with nanocomposite of magnetic nanoparticles (Fe 3 O 4 −CS−CD) and multi-walled carbon nanotubes (MWCNTs). The synergistic effect of chitosan, β-cyclodextrin and MWCNTs can facilitate electron transfer between enzyme and electrode based on the promoting results of the cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The new biosensors exhibited direct electron transfer (DET) from enzyme to electrode after glucose oxidase (GOx) was immobilized on the modified electrode with the nanocomposite. Consequently, the enzymatic glucose biosensor displayed a considerably wide linear range (40 μM to 1.04 mM) with a high sensitivity of 23.59 μA mM −1 cm −2 , low detection limit of 19.30 μM, good selectivity, reproducibility and repeatability for detecting glucose. In addition, the current response still retained at 93.4 % after 25 days. Furthermore, the practical application of glucose biosensor was test in human serum samples with satisfactory accuracy, demonstrating promising and practical potential in biomedical diagnostics.
✓ 已验证
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2022
·
IF 4.326
Haiyang Li,Xuanhe Ru,Ying Song,Huanping Wang,Chenhui Yang,Shuirong Zheng,Lei Gong,Xiaoguang Zhang,Hongji Duan,Zhenguo Liu,Qiuyu Zhang,Yanhui Chen
There is a pressing demand for efficient electromagnetic interference (EMI) shielding materials with strong electromagnetic wave absorption and low reflection for the protection of next-generation communication technologies and wearable electronic devices. In this work, silicone rubber/MXene/Fe3O4 (SRMF) composites with a sandwich-like structure were fabricated using vacuum-assisted dipping and curing. The top and bottom layers of the SRMF composites are magnetic layers containing Fe3O4 particles and silicone rubber (SR), while the middle layer is a 3D conductive network of MXene aerogel film and SR. This sandwich-like structure enables the composites to effectively shield incident electromagnetic waves and improve the absorption of electromagnetic waves through a mechanism of “absorption–reflection–reabsorption”. The electromagnetic shielding performance of a sandwich-structured SR composite containing 1.2 wt % MXene and 20 wt % Fe3O4 reached 55.5 dB, which was higher than that of a blended SRM1.2F20b composite containing the same proportion of MXene and Fe3O4 (23.1 dB), while the power coefficient of reflectivity was 0.65. The SRMF composites also retained their EMI shielding performance after 1000 bending cycles and displayed good tensile strength. These flexible SRMF composites have broad application prospects in the field of electromagnetic protection of wearable devices.
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 48
·21853-21868
·
IF 4.682
Yang Hongzhi,He Tianpei,Wu Yaohui,Luo Jinhua,Zhang Aihua,Chen Xiaoyong,Zeng Yelin,Wang Yonghong,Zhao Yunlin,Wang Guangjun
A novel PbMoO 4 @MBC (MBL-2) magnetic heterojunction photocatalyst was prepared by the successful loading of Fe 3 O 4 with PbMoO 4 onto the highly conductive BC surface through the integration of co-precipitation and pyrolysis. Using advanced characterization methods could reveal the composition, morphology, and optoelectronic properties of the material. The results showed that using BC as the electron transfer interface provided a pathway for charge transfer between Fe 3 O 4 and PbMoO 4 , and importantly, the PbMoO 4 @MBC (MBL-2) nanocomposite had a large specific surface area, excellent magnetic response, high light absorption capacity for efficient carrier separation, and thus the photocatalytic activity was high. The degradation rate of MBL-2 for TC under visible light was as high as 89%. More importantly, PbMoO 4 @MBC (MBL-2) possessed good stability and reusability. The Z-scheme electron transfer pathway for improved photocatalytic performance was proposed by radical capture experiments and electron spin resonance (ESR) measurement analysis. Graphical abstract
✓ 已验证
DOI
高影响因子
DALTON TRANSACTIONS
·
2017
·Vol. 47
·期 5
·1666-1673
·
IF 4.029
Yan Lv,Lin Yue,Qian Li,Baoyi Shao,Sen Zhao,Haitao Wang,Shijia Wu,Zhouping Wang
Herein, the design and synthesis of a multifunctional (Fe3O4-NaYF4:Yb,Tm)@TiO2 photocatalyst through a facile sol–gel process combined with electrostatic self-assembly has been reported. Particularly, as an upconversion sensor, NaYF4:Yb,Tm nanoparticles have the ability to convert near-infrared (NIR) light into ultraviolet (UV) emissions, so that the catalytic body TiO2 can indirectly utilize the NIR part of sunlight but not UV light. The excellent photocatalytic activity of the hybrid samples is evaluated using a model of the degradation of methylene blue (MB). Most importantly, the obtained materials exhibit remarkable magnetic properties because of the addition of a magnetic component (Fe3O4), therefore, the photocatalysts possess desired recyclability and reusability, which is significant for actual applications. Finally, the possible photocatalysis mechanism of the nanohybrids is discussed and hydroxyl radicals (OH˙) are confirmed as the main reactive species.
✓ 已验证
DOI
PubMed
高影响因子
RUSSIAN JOURNAL OF APPLIED CHEMISTRY
·
2020
·Vol. 93
·期 9
·1399-1411
·
IF 0.69
Sun Li,Wu Xiaohong,Zhou Youning,Wang Chunpu,Meng Zhonghua,He Jian
Abstract The halloysite-iron oxide (Fe 3 O 4 –HNTs) hybrid material is prepared using a halloysite nanotube as precursor, and the Fe 3 O 4 is immobilized on the halloysite with subsequent modification using 3-aminopropyltriethoxysilane. The influence of pH, urea hydrolysis, and the concentration of ferric chloride, polyvinyl alcohol on the synthesis of Fe 3 O 4 –HNTs hybrid materials were investigated. FT-IR was used to understand the modification of surface functionality, while the surface morphology and surface heteroatom were investigated through SEM and XPS, respectively. The phase purity of the hybrid material was studied using XRD pattern. The investigation demonstrated that the dispersion of Fe 3 O 4 –HNTs composite in epoxy resin is better than HNTs, and a significance improvement in corrosion resistance of epoxy coatings (EP) was observed. Moreover, an attempt was made to understand the mechanism of Fe 3 O 4 –HNTs/epoxy coating.
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）