Nature Communications
·
2026
·
IF 18.1
Jia Junqi,Liu Yu,Yu Jiamin,Wang Jingwei,Zhang Yiting,Fang Yuan,Yu Ying,Sun Zhongxing,Li Zhuoning,Tang Yin,Shao Juejia,Zhang Yanjun,Song Hai,Ulianov Sergey V.,Huang Jing,Fang Dong
Histone H3 lysine 36 dimethylation (H3K36me2) plays a key role in transcriptional elongation and chromatin organization, yet how its deposition is spatially controlled across the genome remains unclear. Here, we identify TOP1 as a critical recruiter of the H3K36me2 methyltransferase NSD2 to gene bodies. Disruption of the TOP1–NSD2 interaction reduces H3K36me2 at gene bodies, impairs RNA polymerase II release, and represses transcription. Remarkably, loss of this recruitment increases H3K36me2 at repetitive sequences, licensing their aberrant transcriptional activation. We show that NSD2 is primarily responsible for depositing H3K36me2 at these loci. We further identify MTA1 as a recruiter of NSD2 to repetitive elements via recognition of the GATC consensus sequence. Together, TOP1 and MTA1 spatially partition NSD2 across the genome, enabling H3K36me2 to serve dual roles in regulating canonical gene expression and acting as an active mark for the transcriptional activation of repetitive sequences.
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WATER AIR AND SOIL POLLUTION
·
2026
·Vol. 237
·期 21
·1248
·
IF 3.5
Zhang Liping,Mu Ran,Liu Siying,Li Huitong,Cui Yujing,Yan Zhao,Sun Runchao
Polyethylene glycol-400 (PEG-400), a critical lubricant in photovoltaic silicon wafer slicing, is highly recalcitrant to biodegradation and environmentally persistent. Direct discharge of PEG-400 not only induces water eutrophication and disrupts aquatic ecosystems but also poses chronic health risks to humans through long-term environmental accumulation and water contamination. However, conventional wastewater treatment technologies exhibit limited efficiency in removing PEG-400. In this study, the degradation of PEG-400 was systematically investigated using an O 3 + H 2 O 2 + Mn-Cu/γ-Al 2 O 3 catalytic oxidation process. Single-factor experiments combined with response surface methodology were employed to optimize the catalyst preparation and reaction parameters. Finally, the degradation mechanism and pathway are revealed. The results showed that the Mn-Cu/γ-Al 2 O 3 catalyst prepared under the conditions of 0.1 mol/L impregnation concentration, 500℃ calcination temperature, and 2 h calcination time achieved the optimal catalytic activity. Under the optimal conditions of O 3 concentration of 60 mg/L, H 2 O 2 dosage of 1.8 mmol/L, catalyst dosage of 4 g/L, gas flow rate of 400 mL/min, and reaction time of 90 min, the removal rate of PEG-400 reached 100%, with COD and TOC removal rates of 76.3% and 53.76%, respectively. Radical quenching experiments confirmed that ·OH, ·O 2 − and 1 O 2 were the dominant reactive oxygen species. FTIR and GC–MS analysis revealed that PEG-400 degraded via ether bond cleavage into intermediate products (e.g., aldehydes, carboxylic acids), which verified non-toxicity by T.E.S.T software, and ultimately mineralized into CO 2 and H 2 O.
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Science China-Materials
·
2026
·
IF 7.7
Zhang Chenxu,Li Ziyan,Zhao Linfei,Li Yajun,Yin Qing,Zhao Danyang,Li Yongzhi,Xiao Bin,Meng Qingkun,Ren Yaojian,Xue Xiaolan,Wei Fuxiang,Sui Yanwei,Wu Xiangfeng,Qi Jiqiu,Ho Johnny C.
Electrochemical water splitting is crucial for the scalable production of green hydrogen; however, the practical implementation requires cost-effective electrocatalysts with high activity and durability. This study introduces a low-cost, three-dimensional (3D) nanoporous ZrVFeCoNi material, fabricated via chemical dealloying, at just 0.16% of the cost of Pt. The structure-activity relationship between its microstructure and hydrogen evolution reaction (HER) performance was systematically explored. The lattice defect effects from multiphase intermetallic compounds, combined with multi-metal synergy, optimize H + adsorption energy and electron transfer kinetics. The 3D nanoporous design provides a high electrochemical surface area with abundant active sites, thereby enhancing electrolyte penetration and reducing interfacial mass transfer resistance. Consequently, the ZrVFe-CoNi electrode exhibits outstanding HER performance, requiring only a 38 mV overpotential to reach 10 mA cm −2 and maintaining stable operation for 1000 h at 500 mA cm −2 . Integrated into a full water electrolyzer (ZrVFeCoNi ∥ IrO 2 /Ni), the system achieves a cell voltage of 1.60 V at a current density of 400 mA cm −2 . Advanced characterization and density functional theory (DFT) calculations reveal that interfacial interactions and charge transfer at heterointerfaces drive the catalytic activity, showcasing the potential of 3D nano-structured multiphase intermetallic compounds as high-performance electrocatalysts for green hydrogen systems.
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CURRENT MICROBIOLOGY
·
2026
·Vol. 83
·期 10
·554
·
IF 2.8
Zheng Xiaoyan,Dong Xinyi,Aziz Sadat Abdulla,Mao Sichao,Liu Yongwang,Xu Xinyi,Chen Xingxiang
Chronic diarrhea in pets features high incidence, often causing vitamin B12 deficiency. Probiotics, which can alleviate or even treat chronic diarrhea by improving intestinal microbial balance, have shown promise. Previously, our laboratory isolated a strain of Limosilactobacillus reuteri (CLAB) with vitamin B12-producing capability from canine feces. However, it had suboptimal palatability and insufficient efficacy against chronic diarrhea and vitamin B12 deficiency. In this study, the CLAB was combined with Enterococcus faecalis and Saccharomyces cerevisiae to formulate a compound probiotic paste. The properties of the paste were comprehensively evaluated via a series of experiments including sensory evaluation, pH testing, microbial colony counting, palatability tests, disease activity index scoring, histopathological analysis, biochemical indicator analysis, and RNA quantification. The results demonstrated that the paste exhibited good stability, safety, and favorable palatability in both dogs and cats. Meanwhile, it significantly alleviated chronic diarrhea and vitamin B12 deficiency in mice. Specifically, the high-dose compound probiotic paste decreased myeloperoxidase and malondialdehyde levels in diarrheic mice from approximately 15.9 and 2.5 nmol/mgprot to about 4.2 and 1.7 nmol/mgprot; increased the total antioxidant capacity content and superoxide dismutase activity from approximately 0.5 nmol/mgprot and 1.0 U/mgprot to about 0.6 nmol/mgprot and 1.6 U/mgprot; and downregulated the relative mRNA levels of interleukin-6, interleukin-1β and tumor necrosis factor-α from approximately 2.1, 2.1 and 2.7 to about 1.2, 1.1 and 1.3, respectively. In conclusion, this study supports the potential use of the compound probiotic paste for preventing and treating chronic diarrhea and improving vitamin B12 deficiency in pets.
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 10
·669
·
IF 5.4
Yang Zitong,Deng Jingyu,Zhang Yili,Qi Wenkai,Zhang Yuxia
A self-signaling electrochemical sensor based on molecular imprinting technology for the detection of Bisphenol A (BPA) in food samples. The sensor was constructed through sequential modification of the electrode with reduced graphene oxide (RGO) and CoNiFe Prussian blue analogue (CoNiFe-PBA), followed by electropolymerization of an MIP film using BPA as template and o-phenylenediamine as monomer. CoNiFe-PBA provides an intrinsic signal at ~ 0.47 V without external probes, originating from synergistic redox interactions among Co, Ni, and Fe. BPA rebinding reduces the signal via steric hindrance, enabling sensitive detection in food samples. Under optimal conditions, the sensor demonstrated a wide linear detection range (0.5–500 nM) and a low detection limit (0.19 nM). Owing to its high selectivity, sensitivity, and accuracy, the sensor offers a reliable approach for precise quantification of trace BPA in complex food matrices. Graphical abstract
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Nature Communications
·
2026
·
IF 18.1
Zhang Jiakang,Yan Wenjian,Peng Cheng,Zhu Mingzhe,Li Zhipeng,Jiang Haokun,Sun He,Lan Mengjiao,Ma Mingjun,Wu Weilin,Liao Yuanyuan,Yan Cui,Su Huaigang,Zhou Zhongmin
Tin dioxide (SnO 2 ) stands as a premier electron transport layer in n-i-p perovskite solar cells (PSCs), yet interfacial defect-induced carrier recombination and energy-level misalignment impede its commercialization. Herein, we engineer a multifunctional polymeric interlayer by introducing polymerizable dimethyldiallylammonium chloride (DADMAC) at the SnO 2 /perovskite interface. The densely cross-linked P-DADMAC network reinforces mechanical interlocking, enhancing interfacial adhesion and stress dissipation. Concurrently, chloride ions (Cl⁻) from P-DADMAC synergistically passivate defects at both the perovskite buried interface and SnO 2 surface, inducing a graded n + -type band bending. This energy-band engineering reduces the heterojunction energy-level offset by 0.24 eV, thereby facilitating efficient charge extraction and minimizing non-radiative losses. Consequently, n-i-p devices achieve a power conversion efficiency (PCE) of 26.34% with a fill factor (FF) of 85.84% (certified: 26.27%), while a 25 cm 2 module (active area: 14 cm 2 ) attains 22.03% PCE (FF > 80%). This work establishes a paradigm for interfacial multifunctionalization in high-performance photovoltaics.
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DOI
PubMed
高影响因子
Science China-Chemistry
·
2026
·
IF 9.8
Wang Jingyi,Shang Tongxin,Sun Yafei,Yang Qian,Zuo Jiahui,Yao Guohua,Shen Wenzhong,Peng Linkai,Lv Wei,Wan Ying
Homogeneous catalysts have great promise for accelerating the sulfur reduction reaction (SRR) and improving sulfur utilization in Li-S batteries without sacrificing energy density. We report that the d charge of the metal site in metal porphyrin (MTPP) catalysts, which is related to the ligand exchange ability by S species, is linearly correlated to the turn-over frequency (TOF) and apparent activation energy ( E a ) in the SRR. MnTPP with a d charge of 1.22 e results in a high TOF of \(37 \, {\rm mol}_{{\rm Li}_{2}{\rm S}} \, {\rm mol}_{\rm metal}^{-1} \, {\rm s}^{-1}\) for Li 2 S precipitation. Lithium-sulfur batteries assembled with the MnTPP catalyst had a low shuttle constant of 0.018 h −1 , as well as a high reversible capacity of 994 mAh g −1 at 1 C and a stable cycling performance with a low capacity decay per cycle of 0.08% after 500 cycles. This work establishes an electronic structure-activity relationship for porphyrin-based catalysts in SRR and provides a strategy for the design of homogeneous catalysts for Li-S batteries.
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Communications Materials
·
2026
·
IF 9.1
Zhang Yuan,Pan Yong,Wu Lijie,Cao Jianguo,Su Xueqiong,Xu Jie,Xie Haixia,Gao Dongwen
This paper presents a method for enhancing the environmental stability of all-inorganic perovskite quantum dots (CsPbBr₃) through ligand engineering. To address the challenge of insufficient stability when directly exposed to the natural environment, the study employed trioctylphosphine, lead stearate, and chlorobenzene as solvents. The results indicate that the modified quantum dots exhibited self-healing behavior after 30 days of exposure to corrosive solutions used in LED fabrication processes, with a significant recovery in photoluminescence intensity. Compared to CsPbBr₃, the intensity increased by 29-fold, 104-fold, 250-fold, and 65-fold after exposure to water, ZnO, TiO₂, and Poly(3,4-ethylenedioxythiophene)-poly(styrene sulfonate) solutions, respectively. Additionally, their luminescence intensity at 100 °C increased by 116%. Stability tests under various natural atmospheric conditions confirmed that the time to complete failure reached 1900 h, 5950 h, approximately 3 years, and approximately 24.5 years in humid-hot, forest, laboratory, and low-temperature environments, respectively. These self-healing quantum dots provide valuable insights for quantum dot stability research and the outdoor application of devices.
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高影响因子
Reaction Kinetics Mechanisms and Catalysis
·
2026
·
IF 2.1
Sun Min,Zhang Yihu,Li Bin,Wang Haiyan,Chen Peng,Li Zijiong
Nitrogen and phosphorus co-doped carbon dots (N/P-CD) were successfully synthesized via a facile and controllable electrochemical exfoliation strategy. In this approach, heteroatom doping is achieved through electrolyte engineering. Compared with conventional high-temperature or multistep synthetic methods, this strategy enables precise regulation of nitrogen and phosphorus incorporation simply by tuning the electrolyte composition, thereby providing an effective platform for the controllable modulation of the electronic structure of carbon dots. The electrocatalytic performance of N/P-CD toward the oxygen reduction reaction (ORR) was systematically evaluated in alkaline media. Benefiting from the synergistic effect between nitrogen and phosphorus dopants, the catalyst exhibits significantly enhanced intrinsic activity. Specifically, compared with undoped carbon dots, the onset potential and half-wave potential are positively shifted by 142 mV and 141 mV. Moreover, compared with the singly doped samples (N-CD and P-CD), N/P-CD exhibits a higher onset potential (0.86 V) and half-wave potential (0.76 V), demonstrating electrocatalytic activity comparable to that of the commercial Pt/C electrode. N/P-CD also demonstrated excellent electrochemical stability, as no significant shift in the CV curves was observed after 5,000 cycles, indicating the outstanding stability of the material. This study demonstrates that N/P-CD, as a low-cost and non-precious metal ORR electrocatalyst, shows promising potential in alkaline oxygen reduction systems and can serve as a scalable and environmentally friendly alternative to conventional Pt-based catalytic systems.
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POLYMER BULLETIN
·
2026
·Vol. 83
·期 8
·406
·
IF 4.2
Li Jiheng,Li Pengfei,Yin Manli,Wang Li,Yang Xiao
Conjugated microporous polymers (CMPs), due to their high surface area, permanent pores and varied molecular structure, have attracted great attention in the past decade. However, it is difficult for most of them to disperse in water because of their hydrophobic molecular skeleton. Thus, they can barely be used in wastewater treatment. Herein, we synthesized three CMPs, two of which contained triphenylamine moieties, and introduced sulfonic group by mild sulfonation reaction. The sulfonated CMPs exhibited excellent dispersity in water and fast removal of cationic dyes property. Especially, the maximum Q e of methylene blue was up to 1330 mg/g due to high surface area, porous structure and a great deal of sulfonic groups. We hope this research can further expand the application scope of CMPs in wastewater treatment.
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高影响因子
Waste and Biomass Valorization
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2026
·
IF 3.1
Shi Demei,Li Mengyu,Zhang Ding,Rong Qian,Yuwen Chao
Inexpensive iron-based catalysts with partially filled 3d orbitals are one of the most prospective catalysts for converting spent polymers into hydrogen-rich gases by microwave. However, most iron-based catalysts synthesized have poor microwave absorption, especially the FeAl catalyst synthesized by microwave combustion, which are mixed with disposable medical masks (DMMs) heated to 201 °C in 1200 W microwave field within 15 min with very slow heating efficiency. Here, the introduction of Cu into the FeAl catalyst led to the catalyst lattice reconstruction and the creation of lattice defects and oxygen vacancies, which improved the electrical conductivity and dielectric properties of the catalyst (FeCuAl). The mixture of FeCuAl catalyst and DMMs can be rapidly heated to about 800 °C within 10 min. The increase of microwave power accelerated the pyrolysis reaction process of DMMs and promoted the effective collision of active centers with hydrocarbons, leading to a decrease in dehydrogenation efficiency. The content of non-condensable gas increased from 73.91 to 80.63 wt% and the hydrogen content decreased from 39.81 to 32.48 vol% as the increase of microwave power from 900 to 1500 W. This work improves the dielectric properties of iron-based catalysts by doping-induced defects, which provides ideas for the development of advanced microwave pyrolysis catalysts. Graphical The alternative text for this image may have been generated using AI.
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JOURNAL OF ELECTRONIC MATERIALS
·
2026
·
IF 2.8
Hou Dusong,Gao Danhong,Liu Hongwei,Deng Hanling,Lu Qianyao,Xiong Fan,Shao Hengwei,Lu Yuanyuan,Wang Mengxin,He Xinjian,Huang Sheng
The advancements in flexible display technology impose stringent demands on the optical properties and environmental stability of perovskite luminescent materials. Addressing the core challenges of poor environmental stability and optical performance degradation in methylammonium lead bromide (MAPbBr 3 ) quantum dots, this study proposes a dual-stability strategy combining “internal crystallization regulation” with “external physical protection.” A ZnO/MAPbBr 3 /PVDF composite film was prepared through synergistic modification with zinc oxide (ZnO) and polyvinylidene fluoride (PVDF), with the optimal ZnO content identified as 40 μL. Under these conditions, the composite film exhibited a green light emission full width at half maximum (FWHM) as low as 19.88 nm and a photoluminescence quantum yield (PLQY) of 76.06%, demonstrating high color purity. After heating at 100°C for 60 min, the PL intensity decayed by only 30%, and after 168 h of immersion in water, it retained 65% of its initial PL intensity, indicating significantly enhanced environmental tolerance. When this film served as the green conversion layer integrated with red CsPbI 3 quantum dot films and GaN blue LEDs to form a white light-emitting diode (WLED), the device achieved a color gamut coverage of 126% of the NTSC standard and 94% of the Rec. 2020 specification. Research indicates that ZnO enhances crystalline integrity by regulating MAPbBr 3 nucleation and growth, while PVDF forms a compact hydrophobic barrier. Their combined effect enhances both the film’s optical performance and environmental stability, enabling WLEDs with ultrawide color gamut that meet the requirements of high-performance flexible display and lighting applications.
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