CRYSTAL GROWTH & DESIGN
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2022
·
IF 4.01
Mengnan Li,Jinling Wang,Xiaoyong Xu,Guobin Ren,Bin Zhu,Minghuang Hong,Zhong Li
Cycloxaprid (CYC) is a potentially commercially available pesticide with high activity, but its further development is limited due to the poor solubility and stability. In this paper, the co-crystallization strategy is applied to improve the physical and chemical properties of CYC for the first time. The cycloxaprid-succinimide (CYC–SM) co-crystal and the cycloxaprid-trifluoromethanesulfonamide (CYC–TS) co-crystal with a stoichiometric ratio of 1:1 between API and co-crystal former were successfully prepared through experimental screening and systemically characterized by powder X-ray diffraction, nuclear magnetic resonance, differential scanning calorimetry, thermogravimetry, Fourier transform infrared spectroscopy, and single-crystal X-ray diffraction techniques. The weak interaction of CYC–SM and CYC–TS co-crystals was quantified and analyzed by quantum chemistry calculations. Compared with CYC–TS, the molecular orbital and lattice energy calculation results of CYC–SM show lower chemical reactivity and better stability, which is consistent with the results of solid-state and solution stability tests. The partially weak interaction remained in the solution, and the weakly basic nature of SM and the relatively slow release of CYC from CYC–SM contributed to the promoted solution stability of CYC–SM. In addition, due to the introduction of SM molecules, the solubility of CYC–SM was significantly improved. The CYC–SM co-crystal could be a candidate solid-state form that provides an opportunity for the further development of CYC.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2022
·
IF 9.965
Rongying Zhu,Yaodong Yu,Renqin Yu,Jianping Lai,Joey Chung-Yen Jung,Shiming Zhang,Yufeng Zhao,Jiujun Zhang,Zhonghong Xia
It remains a huge challenge to develop methanol oxidation electrocatalysts with remarkable catalytic activity and anti-CO poisoning capability. Herein, PtIrNi and PtIrCo jagged nanowires are successfully synthesized via a facile wet-chemical approach. Pt and Ir components are concentrated in the exterior and Ni is concentrated in the interior of PtIrNi jagged nanowires, while PtIrCo jagged nanowires feature the homogeneous distribution of constituent metals. The PtIrNi and PtIrCo jagged nanowires exhibit mass activities of 1.88 A/mg Pt and 1.85 A/mg Pt , respectively, 3.24 and 3.19 times higher than that of commercial Pt/C (0.58 A/mg Pt ). In-situ Fourier transform infrared spectroscopy indicates that CO 2 was formed at a very low potential for both nanowires, in line with the high ratio of forward current density to backward current density for PtIrNi jagged nanowires (1.30) and PtIrCo jagged nanowires (1.46) relative to Pt/C (0.76). Also, the CO stripping and X-ray photoelectron spectroscopy results substantiate the remarkable CO tolerance of the jagged nanowires. Besides, the two jagged nanowires possess exceptional activities toward ethanol and ethylene glycol oxidation reactions. This work provides a novel line of thought in terms of rational design of alcohol oxidation electrocatalysts with distinctive nanostructures .
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JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
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2022
·Vol. 32
·期 5
·2237-2248
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IF 2.036
Liu Cansen,Zhen Haowen,Huang Qishan,Chen Wanlin,Mai Yongjin,Zhang Liuyan,Jie Xiaohua
The dispersity of incorporated particles is critical for the creation of composite coatings with enhanced performance. Here, we propose a mechanical agitation and ultrasound-assisted pulse electroplating technique for producing exfoliated MoS 2 reinforced cobalt-based composite coatings with improved tribological and electrochemical properties. The dispersity of exfoliated MoS 2 and its corresponding effect on the microstructure, microhardness, tribological and electrochemical behaviors of the resultant composite coatings are systematically investigated. The results reveal that the outstanding dispersity of exfoliated MoS 2 in electrolyte is beneficial to its even distribution and incorporation in the composite coating, endowing the resultant composite coatings with a smooth surface, compact structure, high hardness, remarkable antiwear and friction reduction performance as well as superior corrosion resistance. This study offers a strategy for producing high-performance composite coatings with promising practical applications. Graphical Abstract
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JOURNAL OF ELECTRONIC MATERIALS
·
2022
·Vol. 51
·期 2
·522-531
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IF 2.047
Zheng Jie,Chen Jiali,Tang Yu,Shen Kaiyuan,Xiang Yujie,Shen Lanxian,Ge Wen,Yang Peizhi,Deng Shukang
In this study, β -Zn 4 Sb 3 was prepared using the Zn-NaCl mixed-flux method based on the stoichiometric ratio of Zn/Sb/NaCl = (4− x ):3:(7+ x ) ( x = 0, 0.1, 0.2, 0.3). X-ray diffraction results showed that all samples were hexagonal rhombic crystal structures with the space group \(R\overline{3}c\) . A second phase of ZnSb was detected in the samples with x = 0.2 and x = 0.3. In addition, the crystal-cell volume and lattice parameter of all samples increased for the larger ion radius of Na + than Zn 2+ . The transmission electron microscopy image and corresponding area electron diffraction pattern demonstrated that the prepared samples had a complete crystal structure. All samples had hole conduction and exhibited p-type conduction behavior. The carrier concentration of the material increased with increased Na content and decreased Zn, ranging from 8.89 × 10 19 cm −3 to 17.82 × 10 19 cm −3 . Moreover, the thermal conductivity ( κ ) of x = 0–0.2 samples decreased with increased Na content; however, the sample with x = 0.3 had a higher κ owing to the appearance of a ZnSb phase. Thermogravimetric differential thermal analysis showed that no weight loss occurred below the melting point. Eventually, the sample with the nominal composition of β- Zn 3.8 Sb 3 NaCl 7.2 achieved a ZT value of 1.43 at 690 K.
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OPTIK
·
2021
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IF 2.443
Kai Ye,Xiaoliang Yang,Siguo Xiao
Bi 3+ , Mn 2+ co-doped CaZnGe 2 O 6 red long afterglow materials were prepared by high temperature solid state reaction method. The phosphor has broad excitation band ranging from 220 nm to 350 nm with two peaks at 255 nm and 300 nm and can give blue, green and red emission band peaking at 448 nm, 530 nm and 645 nm, respectively. Due to the emission properties of Bi 3+ ions and the Bi 3+ →Mn 2+ energy transfer, the co-doped Bi 3+ ions can not only enhance the PL luminescence of the phosphor, but also adjust the emission color. After irradiation of 300 nm ultraviolet light , the phosphors exhibits long-persistent red phosphorescence. Thermoluminescence tests demonstrate that the introduction of Bi 3+ ions can increase the trap depth and trap concentration, greatly improving the afterglow time and brightness of the CaZnGe 2 O 6 : Mn 2+ phosphor. The present work might provide reference for designing new rare earth free red long afterglow materials.
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ChemNanoMat
·
2021
·Vol. 7
·期 6
·635-640
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IF 3.154
Chunfeng Cheng,Jiaqi Shao,Pengfei Wei,Yanpeng Song,Hefei Li,Dunfeng Gao,Guoxiong Wang
Graphical Nitrogen and boron co-doped carbon nanospheres shows an excellent catalytic performance for electrochemical CO 2 reduction reaction and achieves a CO Faradaic efficiency of 95.1% at a low overpotential of 310 mV. The electrochemical CO 2 reduction reaction (CO 2 RR) powered by renewable electricity is a promising route to close the carbon cycle, but it suffers from low product selectivity and high overpotential. Here we develop nitrogen and boron co-doped hollow carbon spheres (NB−CS) through the pyrolysis of a mixture comprising low-molecular-weight phenolic resols, melamine and boric acid. The optimized NB−CS catalyst presents high CO 2 RR performance and achieves a CO Faradaic efficiency of 95.1% at a low overpotential of 310 mV, superior to carbon spheres doped with nitrogen or boron alone. Structural and electrochemical characterizations indicate that the efficient CO 2 RR to CO over the NB−CS catalyst is likely ascribed to the unique graphitized architecture along with high conductivity, large surface area and high density of exposed N and B reactive sites. This work highlights opportunities to use cost-effective and readily available carbon nanomaterials as efficient CO 2 RR catalysts.
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Acta Biomaterialia
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2021
·
IF 8.947
Wenjuan Huang,Sijie Zhou,Bojiao Tang,Hongyan Xu,Xiaoxiao Wu,Na Li,Xingjie Zan,Wujun Geng
Proteins play key roles in most biological processes , and protein dysfunction can cause various diseases. Over the past few decades, tremendous development has occurred in the protein therapeutic market due to the high specificity, low side effects, and low risk of proteins. Currently, all protein drugs on the market are based on extracellular targeting; more than 70% of intracellular targets remain un-druggable. Efficient delivery of cytosolic proteins is of significance for protein drugs, advanced biotechnology and molecular cell biology. Herein, we developed a co-assembly strategy for protein-hexahistidine-metal for intracellular protein delivery. Based on the coordinative interaction between His 6 and metal ions, various proteins were encapsulated in situ into nanosized and positively charged protein encapsulation particles( [email protected] ) through a co-assembly process with a high loading capacity and loading efficiency. [email protected] was able to deliver proteins with diverse physicochemical properties through multiple endocytosis pathways, and the protein could quickly escape from endosomes. In addition, the bioactivity of the loaded protein during co-assembly and the intracellular delivery processes were well preserved and could be properly exerted inside cells. Our results demonstrate that this strategy should be a valuable platform for protein delivery and has huge potential in protein-based theranostics. Statement of significance Intracellular targets with protein drugs may provide a new way for the treatment of many refractory disease. Herein, we developed a co-assembly strategy for protein-hexahistidine-metal for efficient intracellular protein delivery. Based on the coordinative interaction between His 6 and metal ions, various proteins were encapsulated in situ into nanosized and positively charged particles ( [email protected] ) with a high loading efficiency. [email protected] was able to deliver different proteins through multiple endocytosis pathways, and the protein could quickly escape from endosomes. In addition, the bioactivity of the loaded protein during co-assembly and the intracellular delivery processes were well preserved and could be properly exerted inside cells. This strategy should be a valuable platform for protein delivery and has huge potential in protein-based theranostics.
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BIOMATERIALS
·
2021
·
IF 12.479
Jichun Yang,Shuojiong Pan,Shiqian Gao,Tianyu Li,Huaping Xu
Carbon monoxide (CO) therapy and antiangiogenesis therapy (AAT) are regarded as promising approaches for cancer treatment. However, the poor tumor targeting ability and inevitable side effects prevent their clinical application. In this study, we developed H 2 O 2 -responsive diselenide-containing micelles that combined CO therapy with chemosensitization therapy and AAT in a single system. Under the interaction of intratumoral H 2 O 2 , CO and gemcitabine (GEM) were released in situ from the micelles to reduce side effects, and CO significantly sensitized the chemotherapeutic effect of GEM by elevating the level of reactive oxygen species (ROS) in human gastric cancer AGS cells. Furthermore, diselenide bonds in the micelles were oxidized to seleninic acid in organic form, which suppressed the expressions of vascular endothelial growth factor (VEGF) and matrix metalloproteinase-2 (MMP-2) to realize AAT. This study provides an integrated solution to combine CO therapy with chemosensitization therapy and AAT together with good biocompatibility .
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Nature Communications
·
2020
·Vol. 11
·期 1
·1-7
·
IF 12.121
Tian Jinshu,Tan Jiangqiao,Zhang Zhaoxia,Han Peijie,Yin Min,Wan Shaolong,Lin Jingdong,Wang Shuai,Wang Yong
Direct oxidation of methane to value-added C 1 chemicals (e.g. HCHO and CO) provides a promising way to utilize natural gas sources under relatively mild conditions. Such conversions remain, however, a key selectivity challenge, resulting from the facile formation of undesired fully-oxidized CO 2 . Here we show that B 2 O 3 -based catalysts are selective in the direct conversion of methane to HCHO and CO (~94% selectivity with a HCHO/CO ratio of ~1 at 6% conversion) and highly stable (over 100 hour time-on-stream operation) conducted in a fixed-bed reactor (550 °C, 100 kPa, space velocity 4650 mL g cat −1 h −1 ). Combined catalyst characterization, kinetic studies, and isotopic labeling experiments unveil that molecular O 2 bonded to tri-coordinated BO 3 centers on B 2 O 3 surfaces acts as a judicious oxidant for methane activation with mitigated CO 2 formation, even at high O 2 /CH 4 ratios of the feed. These findings shed light on the great potential of designing innovative catalytic processes for the direct conversion of alkanes to fuels/chemicals.
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CHINESE JOURNAL OF CATALYSIS
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2021
·
IF 8.271
Longfu Wei,Changlin Yu,Kai Yang,Qizhe Fan,Hongbing Ji
Currently, air pollution is being exacerbated by rapid social, economic, and industrial development. Major air pollutants include volatile organic compounds (VOCs) and CO. Photocatalytic and thermocatalytic technology can be used to convert VOCs and CO into harmless gases effectively. Recently, photothermal synergistic catalysis has aroused much attention because of its higher performance than those of individual photocatalytic and thermocatalytic processes. There have been many reviews on separate photocatalysts and thermocatalysts for the treatment of VOCs and CO, but few reviews have focused on photothermal synergistic catalysis. In this minireview, we concentrate on recent progress into photothermal synergistic catalysis for the efficient removal of VOCs and CO. The treatment of typical VOCs (such as benzene, toluene, ethanol, formaldehyde, acetone, propylene , and propane) and CO are summarized and analyzed. Furthermore, we discuss the use of conventional reactor technology, such as fixed-bed quartz reactors, for VOCs and CO removal. We also discuss the mechanism of the photothermal synergistic catalytic removal of VOCs and CO. Finally, we present perspectives for the photothermal synergistic catalytic removal of VOCs and CO.
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Advanced Science
·
2021
·Vol. 8
·期 8
·2003941
·
IF 16.806
Xian Sun,Xiaochuan Zhang,Xiaohong Ren,Hongyu Sun,Li Wu,Caifen Wang,Xiaohui Ye,Peter York,Zhaobing Gao,Hualiang Jiang,Jiwen Zhang,Xianzhen Yin
The effective pulmonary deposition of inhaled particulate carriers loaded with drugs is a prerequisite for therapeutic effects of drug delivery via inhalation route. Revealing the sophisticated lung scaffold and intrapulmonary distribution of particles at three-dimensional (3D), in-situ, and single-particle level remains a fundamental and critical challenge for dry powder inhalation in pre-clinical research. Here, taking advantage of the micro optical sectioning tomography system, the high-precision cross-scale visualization of entire lung anatomy is obtained. Then, co-localized lung-wide datasets of both cyto-architectures and fluorescent particles are collected at full scale with the resolution down to individual particles. The precise spatial distribution pattern reveals the region-specific distribution and structure-associated deposition of the inhalable particles in lungs, which is undetected by previous methods. Overall, this research delivers comprehensive and high-resolution 3D detection of pulmonary drug delivery vectors and provides a novel strategy to evaluate materials distribution for drug delivery.
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ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Caihong Fang,Xiaomin Jiang,Jinwu Hu,Jiaojiao Song,Na Sun,Deliang Zhang,Long Kuai
Ruthenium nanocrystals with small size and special morphology are of great interest in various catalytic reactions due to their high activities. However, it is still a great challenge to downsize these nanocatalysts to a sub-nano scale (<2 nm). Herein, we reported a synthesis of ultrasmall size and uniform Ru nanoparticles through a rapid one-pot method. The prepared Ru nanocrystal shows a wormlike shape, in which the diameter is as thin as 1.6 ± 0.3 nm and the length is 13.6 ± 4.4 nm. These Ru nanoworms (NWs) are quite steady during the synthetic process even though the reaction time was further prolonged. We also examined their catalytic activity toward CO oxidation by loading Ru NWs on TiO2 to form Ru NWs/TiO2 catalysts. These catalysts exhibit a high activity of 100% CO conversion at 150 °C, which is much lower than the normal Ru NPs/TiO2 nanostructures. Based on our detailed investigations, we proposed that the small size, special morphology, and TiO2 support are the keys for their significantly improved catalytic activity. We believed that these reasonable discoveries provide a methodology and opportunity to get highly active catalysts for CO oxidation by a detailed increase in their active sites.
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