TOXICOLOGY IN VITRO
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2020
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IF 2.959
Qian Liu,Wentao Shao,Zhenkun Weng,Xin Zhang,Guipeng Ding,Cheng Xu,Jin Xu,Zhaoyan Jiang,Aihua Gu
Bisphenol A (BPA) has a variety of adverse effects on human health; therefore, BPA analogs are increasingly used as replacements. Notably, recent studies have revealed that BPA exposure induced hepatic lipid accumulation, but few studies are available regarding the similar effects of other bisphenol analogues (BPs). Thus, in the present study, a high-content screening (HCS) assay was performed to simultaneously evaluate the hepatic lipid accumulation of 13 BPs in vitro . The BPs induced lipid deposition in HepG2 cells ranking as below: 4,4′-thiodiphenol (TDP) < bisphenol S (BPS) < 4,4′-dihydroxybenzophenone (DHBP) < tetrabromobisphenol A (TBBPA) < tetrachlorobisphenol A (TCBPA) < bisphenol E (BPE) < bisphenol F (BPF) < bisphenol B (BPB) < bisphenol AF (BPAF) < bisphenol A (BPA) < bisphenol C (BPC) < tetramethylbisphenol A (TMBPA) < bisphenol AP (BPAP). Meanwhile, Oil Red O staining and triacylglycerol detection further validated the lipid accumulation elicited by the latter 8 BPs, which exhibited the more significant effects on lipid deposition. Mechanistically, significantly increased expressions of genes involved in fatty acid synthesis and nuclear receptors and decreased levels of genes associated with fatty acid β-oxidation were observed under BPs treatment. Therefore, the present work is the first to systematically provide direct evidence for BPs-induced hepatic lipid accumulation in vitro via HCS, which can be helpful for safety assessments of BPs.
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MICROCHEMICAL JOURNAL
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2020
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IF 3.594
Qi Zhang,He Mei,Wantong Zhou,Xuedong Wang
Herein, we provide the first report on the effects of Ce 3+ addition on the fluorescence of copper nanoclusters (CuNCs), which have excellent optical properties and lower toxicity as compared to AgNCs and AuNCs. We synthesized glutathione-encapsulated copper nanoclusters (GSH-CuNCs) using a simple one-pot chemical reduction approach. The excitation/emission wavelengths of the GSH-CuNCs were 350/650 nm. Introduction of Ce 3+ triggered an aggregation-induced emission of GSH-CuNCs due to formation of GSH-CuNCs-Ce 3+ complexes, resulting in a prominent fluorescence enhancement (~42-fold) of the mixed system. Fluorescent intensities (FIs) for the GSH-CuNCs-Ce 3+ system were significantly quenched by introduction of p -nitrophenol ( p -NP). The aforementioned quenching mechanism resulted from an inner-filter effect producing nearly unchanged fluorescence lifetime and overlap between UV–Vis absorption of Ce 3+ and the excitation wavelength of GSH-CuNCs. Consequently, a GSH-CuNCs-Ce 3+ -based “ON-OFF” platform was constructed for fluorescent detection of p -NP in water matrices. Under optimized conditions (5-min incubation time, pH = 5.6, 20 mM Ce 3+ ), the FIs of the GSH-CuNCs-Ce 3+ system were linear for p -NP concentrations from 0.5 to 500 μM and achieved a low detection limit of 0.17 μM. Moreover, the as-constructed nanofluoroprobe demonstrated high stability and specificity to p -NP, thereby offering a simple, cheap and robust experimental method for conventional monitoring of p -NP at trace levels in real-world water samples.
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CHEMICAL ENGINEERING JOURNAL
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2020
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IF 10.652
Lei Wang,Yuanyuan Liu,Juan Han,Yihan Liu,Huiling Lan,Chunmei Li,Yun Wang
Enzyme-nanoMOFs, a very recent and emerging green biocatalyst, has been widely researched to pursue the improvement of enzyme stability. However, MOFs coating decreases substrate accessibility and possesses nanometer size, thus restraining enzyme activity and controllable recycling. Here, inspired by natural biomineralization , we created a morphology-dependent intelligent [email protected] biocatalyst via rationally in situ tailoring the morphology of enzyme-nanoMOFs for enhancing the combination of substrate aptamers. The resulting [email protected] nanoflowers achieved an “on-demand” tuning of functionality, where self-enriching substrate by substrate aptamers acted in synergy with [email protected] enzyme mimics to significantly boost catalytic activity during biocatalysis. Moreover, after completing the catalytic reaction , easily magnetic separation and then competitive release to automatically start the cyclic catalysis were provided by automatic structure switch of aptamer-cDNA hybridization and aptamer-substrate binding. The degradation of BPA with laccase-Cu 3 (BTC) 2 @P1 reached 4.4-fold improvement in the catalytic efficiency. Laccase-Cu 3 (BTC) 2 @P1 could be controllably recycled to retain 76% initial activity after 8 catalytic cycles. These catalytic and recyclable performances were much better than laccase-Cu 3 (BTC) 2 . The combination of the unique morphology of enzyme-nanoMOFs and performance of aptamers brings hope for the industrial application of intelligent [email protected] systems.
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Analytical Methods
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2020
·Vol. 13
·期 1
·133-140
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IF 2.596
Jinna Zhang,Haiyang Wang,Longhua Xu,Zhixiang Xu
A novel mesoporous fluorescent molecularly imprinted sensor for selective detection of bisphenol A (BPA) in food materials was fabricated via a semi-covalent imprinting method. The imprinting precursor that served as an alternative template molecule for BPA was prepared via thermally reversible isocyanate bonding, which effectively improved the imprinting efficiency for the molecularly imprinted sensor. Carbon dots (CDs) were embedded in mesoporous silica as signal recognition elements that exhibited quenching upon BPA binding. Subsequently, through the sol–gel process, the molecularly imprinted layer was coated on the CDs silica layer and provided specific recognition sites for BPA. The composite of CDs embedded in the mesoporous molecularly imprinted polymer (CDs@MIP) was characterized with scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, Brunauer–Emmett–Teller measurements and thermogravimetric analysis. The mechanism of carbon dots quenching and the high selectivity of CDs@MIP towards BPA were explored. The linear response range of the sensor was from 0.025 mg L−1 to 2 mg L−1 with a limit of detection of 0.016 mg L−1. The method was successfully applied for the determination of food samples and recoveries ranged from 92.5% to 101.1%. The BPA contents in actual samples were determined using high performance liquid chromatography and the proposed sensor, showing no significant difference between the two methods.
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CHEMOSPHERE
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2020
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IF 5.778
Xiaoping Liao,Caixiang Zhang,Chao Nan,You Lv,Zenghui Fan,Lisong Hu
Manganese oxides (MnO 2 ), important environmental oxides, have drawn significant attention in areas such as detoxification of micro-hazardous organic contaminants with electron-donating functional groups such as –OH. However, studies on whether these oxidized processes might further impact the fate of some esters like organophosphorus pesticide (OPPs) remain poorly understood. Herein, we propose a new mechanism involved in the enhanced removal of methyl parathion in mixtures of MnO 2 and phenol. Specifically, the removal of methyl parathion (up to 73.7%) was significantly higher for a binary system than for MnO 2 alone (approximately 9.3%) and was primarily due to adsorption rather than degradation. The extent of methyl parathion adsorption was dependent significantly on pH, reactant loading and metal ion co-solutes (such as Ca 2+ , Mg 2+ , Fe 3+ and Mn 2+ ). Both spectroscopic (FT-IR, SEM-EDX and XPS) and chromatographic (LC/HRMS) analyses showed that the remarkable increase in the number of organics (e.g., polymers) onto the MnO 2 surface dominated methyl parathion adsorption via hydrogen bonding, n-π and π-π interactions, van der Waals forces and pore-diffusion. The results from this study provided evidence for the role of manganese oxides in adsorption of methyl parathion in soil-aquatic environments involving phenolic compounds .
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CHEMICAL ENGINEERING JOURNAL
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2020
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IF 10.652
Yan Sun,Lu Xu,Pengkang Jin,Xue Bai,Xin Jin,Xuan Shi
It is well known that pristine titanium dioxide (TiO 2 ) is unable to absorb and utilize visible light to degrade organics and reduce hexavalent chromium (Cr(VI)). However, for the first time, this research found that when some organic compounds were mixed with hexavalent chromium, titanium dioxide could not only degrade organic compounds but also reduce hexavalent chromium synchronously under the drive of visible light. The pristine TiO 2 exhibited excellent simultaneity removal of bisphenol A (BPA) and Cr(VI) under visible light irradiation, and almost 100% BPA (50 mg/L) and 100% Cr(VI) (10 mg/L) were removed just within 60 min. Photoluminescence (PL), electrochemical characterization and chemical quenching studies suggested that the reaction mechanism is similar to dye sensitization and electron transfer is responsible for the superior recation. Influences of different reaction conditions were systematically investigated, such as the initial concentration of BPA, the crystal structure of TiO 2 , the catalyst dosage, the initial pH value, and the common inorganic anions. Compared to the rutile, anatase exhibited the most remarkable performance for BPA degradation and Cr(VI) reduction under visible light irradiation. In addition, many other typical refractory organics, such as acetaminophen and tetracycline, have been successfully applied in this photocatalytic system of TiO 2 under visible light irradiation (TiO 2 /Vis system) to synergistically remove self-contamination and Cr (VI) pollution. The findings of the present study provide a valuable insight for sewage treatment, especially the composite wastewater containing organic pollutants and the hexavalent chromium.
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SCIENCE OF THE TOTAL ENVIRONMENT
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2020
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IF 6.551
Keren Lu,Zijun Min,Jiaxing Qin,Penghui Shi,Junfeng Wu,Jinchen Fan,Yulin Min,Qunjie Xu
Herein, we report a method to synthesize nitrogen self-doped hierarchical porous carbon materials derived from chitosan. This method uses potassium hydroxide (KOH) activation and rapid-freezing technology . The catalyst (CA-900Q 1–1) obtained after rapid-freezing and KOH activation treatment show excellent persulfate activation ability. It can remove 20 mg bisphenol A (BPA) within 10 min better than traditional metal oxidate and nanomaterials . In the aquatic environment, CA-900Q 1–1 has a high resistance to inorganic anions. CA-900Q 1–1, possessing a high proportion of graphitic nitrogen, provides a sufficient number of active sites for persulfate activation. In addition, the catalyst yielded sizeable specific surface areas (SSAs) (1756.1 m 2 /g) and a hierarchical pore structure, which helps to improve the mass transfer in the carbon framework. The efficient adsorption of pollutants by the catalyst shortens the time required for target organic molecules to migrate to the catalyst surface and hierarchical pore structure. Furthermore, the catalyst has excellent electrical conductivity ( R = 1.73 Ω), which enables pollutants adsorbed on the catalyst surface to transfer electrons to the persulfate through the N-doped sp 2 -hybrid carbon network faster.
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BIORESOURCE TECHNOLOGY
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2020
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IF 7.539
Xiupeng Jiang,Yuanyuan Yan,Leiyu Feng,Feng Wang,Yingqing Guo,Xianzhong Zhang,Zhenguang Zhang
Bisphenol A (BPA), a typical persistent organic pollutant in waste activated sludge, was chosen to explore its influence on the accumulation of volatile fatty acids (VFAs), which is an important raw material, during anaerobic fermentation. BPA in the range of 0–200 mg/kg dry sludge was beneficial to VFAs production, from 1564 mg chemical oxygen demand (COD)/L in the control to 2095 mg COD/L with 50 mg/kg BPA; the acetic acid yield was 563 and 1010 mg COD/L with 0 and 50 mg/kg BPA, respectively. The abundance of microorganisms that can consume VFAs was reduced and those responsible for producing VFAs was increased by BPA. Homologous genes of related enzymes in the pathways for amino acid metabolism, fatty acid biosynthesis, ABC transporters and quorum sensing were enhanced in the presence of BPA. The abundance of carbohydrate-active enzymes increased with BPA when compared with the control, benefitting VFAs production.
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JOURNAL OF HAZARDOUS MATERIALS
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2020
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IF 9.038
Xin Li,Shengxiao Zhang,MingMing Zhang,Mingwu Yu,Hou Chen,Huawei Yang,Qiang Xu
A novel FeO X nanoparticles supported biomass activated carbon (BAC/FeO X ) composite was prepared through one-pot calcination method with FeCl 3 and cherry stone powder as precursors. The carbonization of biomass, reduction of Fe 3+ , and FeO X anchored on carbon substrate could be achieved at the same time. Characterization with transmission electron microscope (TEM) and scanning electron microscope indicated that nanoscale FeO X distributed uniformly on carbon substrate, and X-ray photoelectron spectroscopy, X-ray diffraction, and high resolution TEM characterization proved that the loaded FeO X was high crystallinity of Fe 3 O 4 and α-Fe 0 . Bisphenol A (BPA) was used to investigate the degradation performance of BAC/FeO X activating peroxydisulfate (PDS). The ratio of raw materials affected degradation efficiency of BPA intensively through the content, valence state, and dispersibility of FeO X nanoparticles, and the optimal material could degrade 20 mg/L BPA completely in 5 min at 0.1 g/L in the presence of 1 g/L PDS. Free radical determination and quenching experiments indicated that both SO 4 •− and •OH were involved in BPA degradation. The degradation pathway was proposed based on the identification of degradation intermediates. The facile synthesis method, high activation efficiency, and low-cost and environmental friendly raw materials made the BAC/FeO X -50 an alternative catalyst for organic pollution water treatment .
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JOURNAL OF MEMBRANE SCIENCE
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2020
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IF 7.183
Yang Yang,Zhu Xiong,Zhu Wang,Yi Liu,Zijun He,Akun Cao,Li Zhou,Lijing Zhu,Shuaifei Zhao
Carbon nanotube (CNT) based adsorbents have attracted extensive research interest for aqueous pollutants removal. However, such adsorbents face the problems of limited adsorption capacities and costly regeneration. Here, we report a highly adsorptive photo-regenerable CNT based multifunctional membrane with excellent self-cleaning properties via the facile vacuum filtration method, followed by FeOOH in-situ anchoring and silver-amino reaction. Various dyes (Rhodamine B, methylene blue, eosin Y and acid orange 7) and emerging contaminants (bisphenol A, amoxicillin and p-nitrophenol) were tested with the CNT based membrane. Our membrane exhibited superior adsorption performance to dyes among CNT based adsorbents reported in literature. In particular, the CNT based composite membrane displayed even better adsorption performance to cationic dyes. The adsorption capacities of the membrane for Rhodamine B and methylene blue were up to 181 and 247 mg/g, respectively. The membrane also had excellent self-cleaning and photo-regenerable properties after severe organic fouling. Our multifunctional CNT based membrane combined the features of adsorption, membrane separation , and catalytic degradation into one system, showing great promise for dye polluted wastewater purification. This study also offers a new strategy to engineer robust adsorptive, self-cleaning and regenerable membranes for wastewater treatment .
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CHEMICAL ENGINEERING JOURNAL
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2020
·
IF 10.652
Min-Ping Zhu,Jia-Cheng E. Yang,Xiaoguang Duan,Shaobin Wang,Darren Delai Sun,Baoling Yuan,Ming-Lai Fu
Immobilizing metal-organic frameworks in macro-supports to form three-dimensional catalysts holds a great promise in environmental remediation, however quantitative structure/property-catalytic activity relationship remains unknown currently. In this work, we constructed Co 2 AlO 4 /CoAl 2 O 4 @Al 2 O 3 monoliths derived from ZIF-67@γ-Al 2 O 3 pellets and systematically investigated their surface chemistry-activity relationships in peroxymonosulfate (PMS) activation for organic degradation. The activities of Co 2 AlO 4 /CoAl 2 O 4 @Al 2 O 3 catalysts were selectively correlated with their ratios of Co 3+ /Co 2+ and O Defect /O Lattice . The optimized Co 2 AlO 4 /CoAl 2 O 4 @Al 2 O 3 demonstrated an excellent catalytic efficacy toward PMS activation for metronidazole removal in a wide pH range (3.29–10.26) and OH was the dominant oxidant for metronidazole oxidation. The catalyst also exhibited desirable performance for eliminating other emerging contaminants and enduring catalytic activity and stability in PMS activation without regeneration. This study provides new prospects in rational design of robust, cost-effective and self-cleaning/repairing three-dimensional Co-based macroscale-catalysts with an outstanding and lasting catalytic activity for water purification.
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CHEMICAL ENGINEERING JOURNAL
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2020
·
IF 10.652
Ningjie Du,Ying Liu,Qiuju Li,Wei Miao,Dandan Wang,Shun Mao
Single-atom catalysts have drawn increasing attention in advanced oxidation due to their unique structure and significant promise in heterogeneous catalysis. Herein, single-atom iron anchored on nitrogen-doped carbon (SAFe-N-C) was synthesized with iron phthalocyanine (FePc) and metal-organic framework (ZIF-8). With thermal treatment and acid leaching, atomically-dispersed Fe-N x sites were successfully formed on the surface of N-C support derived from ZIF-8. The prepared catalyst was demonstrated to activate peroxydisulfate (PDS) for chloramphenicol (CAP) degradation. Compared with N-C, the SAFe-N-C shows 6 times enhanced removal efficiency (from 15.3% to 93.1%) for CAP. Moreover, the catalyst shows high catalytic activity in a wide pH range of 5 to 9 and good resistance to inorganic anions, in which a singlet oxygen-dominated process is found. This study reveals the role of single-atom site in singlet oxygen evolution and offers a new catalytic approach for selective removal of organic pollutants in complex water matrix.
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